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1. 发明授权

KR100530843B1 동충하초 추출물을 유효성분으로 포함하는 항염 조성물 有权
标题翻译：含有作为有效成分的提取物和角质层提取物的抗炎组合物
公开(公告)号：KR100530843B1
公开(公告)日：2005-11-23
申请号：KR1020020070016
申请日：2002-11-12
申请人： 주식회사 웰스킨 , 박경찬
发明人： 박경찬 , 권선방 , 김동석 , 최혜령 , 황인아 , 박서형 , 김순겸
IPC分类号： A61K36/068 , A61P29/00
摘要： 본 발명은 동충하초 추출물을 유효성분으로 포함하는 항염 조성물에 관한 것이다. 본 발명은 인터루킨-1의 생산을 억제하여 피부염증을 억제하는 효과가 우수하고, 인체에 안전한 동충하초 추출물을 포함하는 항염조성물을 제공한다.

2. 发明公开

KR1020040041912A 동충하초 추출물을 유효성분으로 포함하는 항염 조성물 有权
标题翻译：含有丝氨酸钠的抗炎组合物作为有效成分提取物
公开(公告)号：KR1020040041912A
公开(公告)日：2004-05-20
申请号：KR1020020070016
申请日：2002-11-12
申请人： 주식회사 웰스킨 , 박경찬
发明人： 박경찬 , 권선방 , 김동석 , 최혜령 , 황인아 , 박서형 , 김순겸
IPC分类号： A61K36/068 , A61P29/00
CPC分类号： A61K36/062 , A61K8/9706 , A61K36/068 , A61Q19/005 , Y10S514/886
摘要： PURPOSE: Provided is an anti-inflammatory composition containing Cordyceps militaries extract as an effective composition, which inhibits the production of interleukin-1 to have excellent inhibition effect on skin inflammation and is harmless to the human body. CONSTITUTION: An anti-inflammatory composition is characterized by containing as an effective composition, 0.00001-10 wt.% of Cordyceps militaries extract which is obtained by using an extraction solvent selected from the group consisting of water, methanol, ethanol, petroleum ether, chloroform, ethylacetate, normal butanol, acetone, 1,3-butylene glycol, hexane, diethyl ether, normal propanol and iso-propanol.
摘要翻译：目的：提供含有冬虫夏草军事提取物作为有效组合物的抗炎组合物，其抑制白细胞介素-1的产生对皮肤炎症具有优异的抑制作用，对人体无害。构成：抗炎组合物的特征在于，含有作为有效成分的0.00001-10重量％的冬虫夏草军事提取物，其通过使用选自水，甲醇，乙醇，石油醚，氯仿中的提取溶剂而得到乙酸乙酯，正丁醇，丙酮，1,3-丁二醇，己烷，乙醚，正丙醇和异丙醇。

3. 发明授权

KR101198146B1 백반증 완화용 화장품 조성물 有权
标题翻译：用于减轻白癜风的化妆品组合物
公开(公告)号：KR101198146B1
公开(公告)日：2012-11-12
申请号：KR1020070048916
申请日：2007-05-18
申请人： 주식회사 웰스킨
发明人： 박경찬 , 박서형
IPC分类号： A61K31/05 , A61Q19/02 , A61K8/34
摘要： 본 발명은 벤젠디올(benzenediol) 유도체를 포함하는 백반증 완화용 화장품 조성물에 관한 것이다. 더욱 상세하게는 멜라닌 세포의 증식 및 이동을 촉진하여 백반증을 완화하는 벤젠디올(benzenediol) 유도체를 포함하는 백반증 완화 효과를 갖는 화장품 조성물에 대한 것이다.
백반증

4. 发明授权

KR100773475B1 인돌-3-아세트산을 포함하는 광감작제, 및 이를 포함하는광역학적 치료용 키트 有权
标题翻译：含有吲哚-3-乙酸的光敏剂及含有它们的光动力疗法药盒
公开(公告)号：KR100773475B1
公开(公告)日：2007-11-05
申请号：KR1020060063841
申请日：2006-07-07
申请人： 주식회사 웰스킨
发明人： 김동석 , 김소영 , 박경찬
IPC分类号： A61K31/405 , A61K31/404 , A61P35/00
CPC分类号： A61K31/405 , A61K41/0057
摘要： A novel photosensitizer is provided to show relatively high tumor tissue selectivity and minimum side effects. And a composition and a kit for photodynamic therapy comprising the same are provided. A photosensitizer comprises an indole-3-acetic acid represented by the formula(1). A composition for treating cancer comprises 0.001-30 wt.% of the indole-3-acetic acid having the photodynamic activity and is formulated into liquid, semi-solid, solid or aerosol. A kit for treating cancer of skin, digestive organs, urinary organs, genital organs, respiratory organs, circulatory organs, brain and nervous system comprises the composition and a light source for radiating light having a wavelength of 280-1,000 nm and the strength of 1-100J/cm^2.
摘要翻译：提供了一种新颖的光敏剂来显示相对较高的肿瘤组织选择性和最小的副作用。并提供了包含该组合物和用于光动力疗法的试剂盒。光敏剂包含由式（1）表示的吲哚-3-乙酸。用于治疗癌症的组合物包含0.001-30重量％的具有光动力学活性的吲哚-3-乙酸，并且配制成液体，半固体，固体或气溶胶。用于治疗皮肤，消化器官，泌尿器官，生殖器官，呼吸器官，循环器官，脑和神经系统的癌症的试剂盒包括用于辐射波长为280-1,000nm的光的组合物和光源，强度为1 -100J /平方公分。

5. 发明公开

KR1020060069979A 상지 추출물을 포함하는 항염증제 无效
标题翻译：白介素-1介导的抗炎组合物，其含有从破乳细胞分离的提取物
公开(公告)号：KR1020060069979A
公开(公告)日：2006-06-23
申请号：KR1020040108585
申请日：2004-12-20
申请人： 주식회사 웰스킨
发明人： 박경찬 , 권선방 , 김동석 , 박서형
IPC分类号： A61K36/605 , A61P17/00
CPC分类号： A61K36/605 , A61K2236/33 , Y10S514/857
摘要： 본 발명은 상지 추출물을 포함하는 항염증제에 관한 것이다. 특히 본 발명은 인체에 안전하며 인터루킨-1의 생산 및 피부홍반 형성을 억제할 수 있는 상지 추출물을 포함하는 항염증제를 제공한다.
상지, 인터루킨-1, 항염, 홍반 형성 억제

6. 发明授权

KR100514315B1 매트릭스 메탈로프로테아제-1을 억제하는 피부노화 방지용 약학 조성물 有权
标题翻译：包含CORDYCEPS SP的组合物或PAEEILOMYCES JAPONICA提取物抑制基质金属蛋白酶的活性
公开(公告)号：KR100514315B1
公开(公告)日：2005-09-13
申请号：KR1020030000549
申请日：2003-01-06
申请人： 주식회사 웰스킨
发明人： 박경찬 , 권선방 , 최혜령 , 박서형 , 윤진아 , 김순겸
IPC分类号： A61K36/066 , A61P9/10 , A61P29/00 , A61P25/28
摘要： 본 발명은 동충하초 추출물을 포함하는 매트릭스 메탈로프로테아제 억제용 조성물에 관한 것이다. 특히 본 발명은 세포외기질을 분해하는 매트릭스 메탈로프로테아제의 활성을 억제하여 매트릭스 메탈로프로테아제에 의한 질병을 예방 또는 치료할 수 있는 동충하초 추출물, 또는 코디세핀 및 이의 유도체를 유효성분으로 포함하는 매트릭스 메탈로프로테아제 억제용 조성물을 제공한다.

7. 发明授权

KR100458701B1 스핑고리피드 또는 그 대사산물을 함유하는 미백 화장료조성물 有权
标题翻译：关于我们关于我们
公开(公告)号：KR100458701B1
公开(公告)日：2004-12-03
申请号：KR1020000058715
申请日：2000-10-06
申请人： 주식회사 웰스킨
发明人： 박경찬
IPC分类号： A61K8/68 , A61Q19/02
摘要： PURPOSE: A whitening cosmetic composition containing sphingolipid or its metabolite is provided, therefore Akt/PKB can be deactivated to inhibit the growth of melanin cells, and the activity of tyrosinase can be inhibited, to decrease the formation of melanin. CONSTITUTION: The whitening cosmetic composition having inhibiting effect on the growth of melanin cells and formation of melanin contains sphingolipid or its metabolite as active ingredient, in which the sphingolipid or its metabolite, particularly active-ceramide is added into the whitening cosmetic composition in an amount of 0.01 to 30.0 wt.%. The whitening cosmetic composition can be formulated into lotion, emulsion, cream, mask pack or the like.
摘要翻译：目的：提供一种含有鞘脂或其代谢物的增白化妆品组合物，因此可以使Akt / PKB失活以抑制黑色素细胞的生长，并且可以抑制酪氨酸酶的活性，从而减少黑色素的形成。构成：对黑色素细胞生长和黑色素形成具有抑制作用的美白化妆品组合物含有鞘脂或其代谢物作为活性成分，其中鞘脂或其代谢物，特别是活性神经酰胺以一定量为0.01至30.0重量％。增白化妆品组合物可以配制成洗剂，乳剂，霜剂，面膜包装等。

8. 发明授权

KR100445405B1 항산화 및 항균 작용을 갖는 자영지의 수용성 추출물을포함하는 조성물 有权
标题翻译： 항산화및항균작용을갖갖자영추추
公开(公告)号：KR100445405B1
公开(公告)日：2004-08-25
申请号：KR1020010046639
申请日：2001-08-01
申请人： 주식회사 웰스킨
发明人： 박경찬 , 최영 , 김순겸 , 김의종
IPC分类号： A61K8/97 , A61Q19/08 , A61Q17/00
摘要： PURPOSE: Provided is a composition which comprises Ganoderma sinense water-soluble extract having anti-oxidation activity particularly to 1,1-diphenyl-2-picrylhydrazyl radical and hydrogen peroxide protection activity, as well as antibacterial activity. CONSTITUTION: The composition characteristically comprises Ganoderma sinense water-soluble extract which is obtained by the steps of: extracting Ganoderma sinense with 70% ethyl alcohol; concentrating the extract at 50 deg.C then adding purified water thereto to separate a first water soluble extract and a water insoluble extract; adding petroleum, chloroform, ethylacetate and butanol sequentially to the water soluble extract at room temperature to obtain their fractions; adding an extraction solvent to the fractions to obtain a second water soluble extract; and pressure-concentrating and drying each supernatant .
摘要翻译：目的：提供一种组合物，该组合物含有特别是对1,1-二苯基-2-苦基肼基具有抗氧化活性和过氧化氢保护作用以及抗菌活性的灵芝提取物水溶性提取物。构成：该组合物的特征在于含有通过以下步骤获得的灵芝水溶性提取物：用70％乙醇提取灵芝提取物; 将提取物在50℃浓缩，然后向其中加入纯化水以分离第一水溶性提取物和水不溶性提取物; 在室温下将石油，氯仿，乙酸乙酯和丁醇依次加入到水溶性提取物中以获得它们的级分; 向所述级分中加入提取溶剂以获得第二水溶性提取物; 并浓缩并干燥每个上清液。

9. 发明授权

KR100445404B1 홍경천 추출물을 포함하는 미백 조성물 有权
标题翻译： 홍경천추출물을포함하는미백조성물
公开(公告)号：KR100445404B1
公开(公告)日：2004-08-25
申请号：KR1020010046636
申请日：2001-08-01
申请人： 주식회사 웰스킨
发明人： 박경찬 , 최영 , 김순겸
IPC分类号： A61K8/97 , A61Q19/02
摘要： PURPOSE: A whitening composition containing a Rhodiola rosea extract which has excellent whitening action and safety to a human body as a main component is provided which has a toxicity inhibiting action on hydrogen peroxide-inducing cells, an effect of inhibiting human tyrosinase activity and a melamine production-inhibiting action. CONSTITUTION: The whitening composition contains 0.001 to 10% by weight of a Rhodiola rosea extract, based on the total weight of the composition. The Rhodiola rosea extract is extracted from one or more solvents selected from the group consisting of ethanol, petroleum ether, chloroform, ethyl acetate and butanol. The composition is formulated into an emollient lotion, skin lotion, nourishing cream, massage cream, essence, pack, adhesive skin patch or gel.
摘要翻译：目的：提供一种含有玫瑰红景天提取物的美白组合物，其对人体的美白作用和安全性优异，作为主要组分，其对过氧化氢诱导细胞具有毒性抑制作用，抑制人酪氨酸酶活性的作用和三聚氰胺生产抑制作用。构成：基于组合物的总重量，增白组合物含有0.001-10重量％的红景天提取物。红景天提取物是从一种或多种选自乙醇，石油醚，氯仿，乙酸乙酯和丁醇的溶剂中提取的。该组合物被配制成润肤乳液，润肤液，滋养霜，按摩霜，精华液，包装，粘贴性皮肤贴剂或凝胶。

10. 发明公开

KR1020030012564A 항산화 및 항균 작용을 갖는 자영지의 수용성 추출물을포함하는 조성물 有权
标题翻译：包含具有抗氧化和抗细菌活性的GANODERMA SINENSE水溶性提取物的组合物
公开(公告)号：KR1020030012564A
公开(公告)日：2003-02-12
申请号：KR1020010046639
申请日：2001-08-01
申请人： 주식회사 웰스킨
发明人： 박경찬 , 최영 , 김순겸 , 김의종
IPC分类号： A61K8/97 , A61Q19/08 , A61Q17/00
摘要： PURPOSE: Provided is a composition which comprises Ganoderma sinense water-soluble extract having anti-oxidation activity particularly to 1,1-diphenyl-2-picrylhydrazyl radical and hydrogen peroxide protection activity, as well as antibacterial activity. CONSTITUTION: The composition characteristically comprises Ganoderma sinense water-soluble extract which is obtained by the steps of: extracting Ganoderma sinense with 70% ethyl alcohol; concentrating the extract at 50 deg.C then adding purified water thereto to separate a first water soluble extract and a water insoluble extract; adding petroleum, chloroform, ethylacetate and butanol sequentially to the water soluble extract at room temperature to obtain their fractions; adding an extraction solvent to the fractions to obtain a second water soluble extract; and pressure-concentrating and drying each supernatant .
摘要翻译：目的：提供具有抗氧化活性的灵芝水溶性提取物，特别是1,1-二苯基-2-苦基肼基和过氧化氢保护活性以及抗菌活性的组合物。构成：该组合物特征性地包含灵芝水溶性提取物，其通过以下步骤获得：用70％乙醇提取灵芝; 将提取物浓缩在50℃，然后加入纯水以分离第一水溶性提取物和水不溶性提取物; 在室温下将石油，氯仿，乙酸乙酯和丁醇依次加入到水溶性提取物中以得到它们的级分; 向所述馏分中加入萃取溶剂以获得第二水溶性提取物; 并对每种上清液进行压力浓缩和干燥。

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