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1. 发明授权

KR101355678B1 나노섬유시트 형태의 의료용 지지 필름 및 그의 제조방법 有权
标题翻译：纳米纤维片的医用背衬膜及其制备方法
公开(公告)号：KR101355678B1
公开(公告)日：2014-01-28
申请号：KR1020120089320
申请日：2012-08-16
申请人： 주식회사 원바이오젠 , 금오공과대학교 산학협력단
发明人： 김원일 , 권오형 , 박미란 , 김성환
IPC分类号： D04H1/728 , D04H1/4358 , A61L15/22 , A61F13/00 , A61F13/15
CPC分类号： D04H1/728 , A61F2013/00646 , A61F2013/15544 , A61L15/225 , D04H1/4358
摘要： The present invention relates to a nanofiber sheet-type medical support film prepared using electrospinning, and a preparation method thereof. The present invention prepares a nanofiber sheet-type medical support film which is porous and has a nano-sized fiber diameter, by: introducing a water-soluble polymer such as a ethylene oxide/propylene oxide block copolymer into a hydrophilic polyurethane resin, which is a main component, to mix the same; electrospinning the obtained mixture to obtain a nanofiber nonwoven fabric; infiltrating the nanofiber nonwoven fabric in a solvent to dissolve and remove a hydrophilic polymer component; and drying the obtained product. The medical support film obtained according to the present invention has remarkable longitudinal and transverse elasticity, has excellent elasticity and moisture transpiration due to a porous structure inside the film, and shows remarkable biocompatibility due to the minimized residual amount of an organic solvent. [Reference numerals] (AA) F-68 (no addition, 0c); (BB) Surface; (CC,EE) Before impregnation; (DD,GG) After impregnation (24h); (FF) Cross section
摘要翻译：本发明涉及使用静电纺丝制备的纳米纤维片状医用支撑膜及其制备方法。本发明通过将亲水性聚氨酯树脂等环氧乙烷/环氧丙烷嵌段共聚物等水溶性聚合物引入到亲水性聚氨酯树脂中，制备多孔性纳米纤维直径的纳米纤维片状医用载体膜，主要组成部分，混合使用; 静置所得混合物，得到纳米纤维无纺织物; 在溶剂中渗透纳米纤维无纺织物以溶解并除去亲水性聚合物组分; 并干燥得到的产品。根据本发明获得的医用支撑膜具有显着的纵向和横向弹性，由于膜内的多孔结构而具有优异的弹性和湿度蒸腾，并且由于有机溶剂的残留量的最小化，显示出显着的生物相容性。（标号）（AA）F-68（无添加，0c）; （BB）表面; （CC，EE）浸渍前; （DD，GG）浸渍后（24h）; （FF）横截面

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