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    • 5. 发明授权
    • 신규한 혈소판 유래 성장 인자(PDGF) B 폴리펩타이드및 이의 유전자
    • 신규한혈소판유래성장인자(PDGF)B폴리펩타이드및이의유전자
    • KR100742313B1
    • 2007-07-24
    • KR1020060025774
    • 2006-03-21
    • 주식회사 굿메디
    • 배현수강문규신민규홍무창정환석조종운이상문쇼캣파베츠김창숙이화진이은아노삼웅고은정
    • C07K14/71C07K14/00
    • A novel polypeptide of platelet derived growth factor B(PDGF B) and a gene thereof are provided to improve wound-healing effects compared to human platelet derived growth factor B, so that the platelet derived growth factor B is useful for promotion of cell growth, development and differentiation, healing of wound, and treatment of degenerative nerve disease, ischemic nerve disease or nerve disorders. The polypeptide of platelet derived growth factor B(PDGF B) has the amino acid sequence of SEQ ID NO:2. The gene encoding the platelet derived growth factor B(PDGF B) polypeptide has 78th-803th nucleotides in the nucleotide sequence of SEQ ID NO:1 and is isolated from the deer young antler(Cervi parvum Cornu). A composition for promotion of cell growth, development and differentiation, wound healing, and treating degenerative nerve disease, ischemic nerve disease or nerve disorders comprises the polypeptide of platelet derived growth factor B(PDGF B).
    • 提供了一种新的血小板衍生生长因子B多肽(PDGF B)及其基因,以提高与人血小板衍生生长因子B相比的伤口愈合作用,使得血小板衍生生长因子B可用于促进细胞生长, 发育和分化,伤口愈合以及退行性神经疾病,缺血性神经疾病或神经疾病的治疗。 血小板衍生生长因子B(PDGF B)的多肽具有SEQ ID NO:2的氨基酸序列。 编码血小板衍生生长因子B(PDGF B)多肽的基因在SEQ ID NO:1的核苷酸序列中具有第78-803个核苷酸,并且从鹿幼鹿(Cervi parvum Cornu)分离。 用于促进细胞生长,发育和分化,伤口愈合和治疗退行性神经疾病,缺血性神经疾病或神经障碍的组合物包含血小板衍生生长因子B(PDGF B)的多肽。