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    • 3. 发明公开
    • 청결한 피부를 촉진하기 위한 방법
    • 用烷醇胺促进清洁皮肤的组合物和方法
    • KR1020020027200A
    • 2002-04-13
    • KR1020010060901
    • 2001-09-29
    • 존슨 앤드 존슨 컨수머 캄파니즈, 인코포레이티드
    • 콜커티스가노폴스키이리나루켄바흐엘빈
    • A61K8/41A61Q17/00A61Q19/00
    • A61K8/41A61Q19/00
    • PURPOSE: A method reducing the number and severity of acne papules on mammalian skin is provided by topically applying a composition containing alkanolamine in a cosmetically acceptable carrier. Whereby, the composition is effective for promoting clear skin in a patient who is afflicted with acne vulgaris, and safe for continuous use over a long time period. CONSTITUTION: The composition contains about 0.1 to 10% by weight of alkanolamine represented by the formula(1) and additionally about 0.01 to 5% by weight of tyrosine in a cosmetically acceptable carrier. In formula, X, Y and Z are selected from the group consisting of hydrogen, C1-3 alkyl group, C2-4 alkanol group, wherein at least one of X, Y or Z is a C2-4 alkanol group bearing at least one hydroxyl group and optionally at least one carboxyl group. The alkanolamine is selected from the group consisting of ethylaminoethanol, methylaminoethanol, dimethylaminoethanolamine, isopropanolamine, triethanolamine, isopropanoldimethylamine, 2-butanolamine, choline and serine.
    • 目的:通过在美容上可接受的载体中局部施用含有链烷醇胺的组合物来提供减少哺乳动物皮肤上的痤疮丘疹的数量和严重程度的方法。 因此,该组合物可有效促进患有寻常痤疮的患者的清晰皮肤,并可长期安全使用。 构成:组合物含有约0.1至10重量%的由式(1)表示的链烷醇胺,另外在化妆品可接受的载体中含有约0.01至5重量%的酪氨酸。 在式中,X,Y和Z选自氢,C 1-3烷基,C 2-4链烷醇基团,其中X,Y或Z中的至少一个是带有至少一个 羟基和任选的至少一个羧基。 链烷醇胺选自乙基氨基乙醇,甲基氨基乙醇,二甲基氨基乙醇胺,异丙醇胺,三乙醇胺,异丙醇二甲基胺,2-丁醇胺,胆碱和丝氨酸。
    • 4. 发明公开
    • 염증과 홍반의 완화방법
    • 减少炎症和红细胞的方法
    • KR1020020027198A
    • 2002-04-13
    • KR1020010060816
    • 2001-09-28
    • 존슨 앤드 존슨 컨수머 캄파니즈, 인코포레이티드
    • 콜커티스가노폴스키이리나알레레스마가렛클라크패티루켄바흐엘빈
    • A61K31/198
    • A61K8/44A61K8/41A61K31/133A61K31/198A61K45/06A61K2800/75A61Q19/00
    • PURPOSE: Provided is a method for ameliorating redness or inflammation of mammalian skin by topically applying a composition containing an effective amount of a compound selected from alkanolamine, tyrosine or mixtures thereof and a cosmetically acceptable carrier. Whereby, the composition can be used in the treatment of various skin disorders inducing inflammation and erythema. CONSTITUTION: A composition comprising an effective amount of a compound selected from alkanolamine represented by the formula(1), tyrosine or mixtures thereof and a cosmetically acceptable carrier is topically applied to ameliorate redness or inflammation of mammalian skin. In formula, X, Y and Z are selected from the group consisting of hydrogen, C1-3 alkyl group, C2-4 alkanol group, wherein at least one of X, Y or Z is a C2-4 alkanol group bearing at least one hydroxyl group and optionally at least one carboxyl group.
    • 目的:提供一种通过局部施用含有有效量的选自烷醇胺,酪氨酸或其混合物的化合物和美容上可接受的载体的组合物来改善哺乳动物皮肤的发红或炎症的方法。 因此,组合物可用于治疗诱发炎症和红斑的各种皮肤疾病。 构成:包含有效量的选自式(1)所示的链烷醇胺,酪氨酸或其混合物和美容上可接受的载体的化合物的组合物被局部施用以改善哺乳动物皮肤的发红或炎症。 在式中,X,Y和Z选自氢,C 1-3烷基,C 2-4链烷醇基,其中X,Y或Z中的至少一个是带有至少一个 羟基和任选的至少一个羧基。