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    • 1. 发明公开
    • 멜라토닌의 새로운 용도
    • 莫拉汀的新用途
    • KR1020130084047A
    • 2013-07-24
    • KR1020120004749
    • 2012-01-16
    • 전북대학교산학협력단
    • 박상열정재교이유진설재원김재훈박양규이주희
    • A61K31/4045A61K31/40A61P25/28A61P25/00
    • A61K31/4045A23L33/10
    • PURPOSE: Melatonin and a composition containing the same are provided to selectively suppress neurotoxin caused by prion without an effect on cell survival rate and to be used in pharmaceutical products and foods which effectively prevent or treat prion disease. CONSTITUTION: A pharmaceutical composition for preventing or treating prion disease contains melatonin as an active ingredient. The prion disease is selected among: Creutzfeldt-Jakob disease, Kuru disease, Gerstmann-Strsyndrome, and fatal familial insomnia in humans; bovine spongiform encephalopathy (BSE) in cattle; scrapie in sheep; chronic wasting disease (CWD) in deer; and transmissible mink encephalopathy (TME) in mink. A food composition for preventing or treating prion disease contains melatonin.
    • 目的:提供褪黑素及其含有组合物以选择性抑制由朊病毒引起的神经毒素而不影响细胞存活率,并用于有效预防或治疗朊病毒疾病的药物和食品中。 构成:用于预防或治疗朊病毒疾病的药物组合物含有褪黑激素作为活性成分。 朊病毒病选自:Creutzfeldt-Jakob病,Kuru病,Gerstmann-Strsyndrome和人类致命的家族性失眠症; 牛海绵状脑病(BSE); 羊羔羊 鹿的慢性消耗性疾病(CWD); 和貂貂传染性貂脑病(TME)。 用于预防或治疗朊病毒疾病的食物组合物含有褪黑激素。