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1. 发明公开

KR1020110022013A 송악 추출물을 함유하는 미백 화장료 조성물 无效
标题翻译：化妆品组合物，用于包含HEDERA RHOMBEA的提取物的皮肤白化
公开(公告)号：KR1020110022013A
公开(公告)日：2011-03-04
申请号：KR1020110007040
申请日：2011-01-24
申请人： 재단법인 제주테크노파크
发明人： 김기옥 , 한종헌 , 고광효 , 이정아 , 김행범 , 강민철 , 이주엽 , 김봉석 , 고영국 , 진호경 , 안승현 , 진희철 , 이건국 , 이강태
IPC分类号： A61K8/97 , A61Q19/02 , A61Q19/00
CPC分类号： A61K8/97 , A61K36/25 , A61K2236/333 , A61K2236/51 , A61Q19/02 , Y10S514/844
摘要： PURPOSE: A method for preparing Hedera rhombea extract which suppresses melanogenesis and tyrosinase activity is provided to treat melasma, dots, freckles, or hyperpigmentation during pregnancy. CONSTITUTION: A whitening cosmetic composition contains 25-100ug/ml of Hedera rhombea as an active ingredient. A method for preparing ethyl acetate from Hedera rhombea comprises: a step of washing and drying Hedera rhombea by hot air; a step of pulverizing Hedera rhombea; a step of precipitating pulverized Hedera rhombea in an organic solvent, leaching, and filtering; a step of repeating leaching and filtering two or three times; a step of decompressing and freeze-drying to obtain a powder; and a step of partitioning the Hedera rhombea extract with ethyl acetate. The organic solvent is 70% ethanol.
摘要翻译：目的：提供一种抑制黑色素生成和酪氨酸酶活性的Hedera rhombea提取物的方法，用于治疗怀孕期间的黑斑病，斑点，雀斑或色素沉着过度。构成：美白化妆品组合物含有25-100ug / ml Hedera rhombea作为活性成分。一种从海棠菱形体制备乙酸乙酯的方法，包括：用热空气洗涤和干燥新西兰菱形的步骤; 粉碎Hedera rhombea的一个步骤; 在有机溶剂中沉淀粉红色的菱形菱形的步骤，浸出和过滤; 重复浸出过滤两三次的步骤; 减压和冷冻干燥以获得粉末的步骤; 和用乙酸乙酯分配Hedera菱形提取物的步骤。有机溶剂为70％乙醇。

2. 发明授权

KR100829083B1 생리활성을 갖는 애기달맞이 추출물 有权
标题翻译：具有生理活性的OENOTHERA LACINIATA提取物
公开(公告)号：KR100829083B1
公开(公告)日：2008-05-16
申请号：KR1020060071100
申请日：2006-07-28
申请人： 재단법인 제주테크노파크
发明人： 박수영 , 정용환 , 이욱재 , 이정아 , 김지영 , 윤원종 , 오대주
IPC分类号： A61K36/185 , A61P39/06
摘要： 본 발명은 생리활성을 갖는 애기달맞이 추출물에 관한 것이다.
본 발명의 생리활성을 갖는 애기달맞이 추출물은, 애기달맞이(
Oenothera
laciniata ) 전초(全草)를 준비하고, 음건한 다음 분쇄하여 미세분말로 만들어 80 % 에탄올에 침적하고, 이 에탄올 침적물을 초음파를 이용하여 1 시간씩 3 회 추출한 다음, 추출액의 상층액을 회수하여 감압 농축하고, 농축물을 물에 현탁시킨 후, 현탁액을 헥산, 디클로로메탄, 에틸아세테이트, 부탄올로 순차적으로 추출하여 애기달맞이 추출물을 제조하는 것으로 구성된다.
본 발명에 의해 항산화활성, 항염활성, 항암활성 및 항균활성의 생리활성이 뛰어난 애기달맞이 추출물이 제공되며, 애기달맞이 추출물을 활성성분으로 포함하는 생리활성이 뛰어난 조성물이 제공된다.
애기달맞이, 추출, 항산화활성, 항염활성, 항암활성, 항균활성

3. 发明授权

KR100829081B1 항산화활성과 항염증활성을 갖는 뱀톱추출물 有权
标题翻译：具有抗氧化活性和抗炎活性的LYCOPODIUM SERRATUM THUNB提取物
公开(公告)号：KR100829081B1
公开(公告)日：2008-05-16
申请号：KR1020070005487
申请日：2007-01-18
申请人： 재단법인 제주테크노파크
发明人： 박수영 , 정용환 , 이욱재 , 윤원종 , 이정아 , 김지영 , 오대주
IPC分类号： A61K36/11 , A61P39/06 , A61P29/00
摘要： An extract of Lycopodium serratum Thunb is provided to show excellent anti-oxidative and anti-inflammatory activities, thereby being used as a composition for preventing and improving inflammation. An extract of Lycopodium serratum Thunb having the antioxidative activity is characterized in that it is prepared by drying the Lycopodium serratum Thunb in the shade, pulverizing the same into fine powder, precipitating the powder in 80% ethanol, extracting the ethanol precipitate using ultrasonic wave, concentrating supernatant of the extract under reduced pressure, suspending the concentrate with water, and then extracting the suspension with hexane, dichloromethane, ethyl acetate and butanol in sequence.
摘要翻译：提供雪松龙提取物以显示优异的抗氧化和抗炎活性，从而用作预防和改善炎症的组合物。具有抗氧化活性的番茄红素提取物的特征在于通过在阴凉处干燥番茄红素制备，将其粉碎成细粉末，将粉末沉淀在80％乙醇中，用超声波提取乙醇沉淀，在减压下浓缩提取物的上清液，用水悬浮浓缩物，然后依次用己烷，二氯甲烷，乙酸乙酯和丁醇萃取悬浮液。

4. 发明授权

KR100768084B1 생리활성을 갖는 암대극추출물 有权
标题翻译：具有生理活性的EUPHORBIA JOLKINI提取物
公开(公告)号：KR100768084B1
公开(公告)日：2007-10-18
申请号：KR1020060062299
申请日：2006-07-04
申请人： 재단법인 제주테크노파크
发明人： 박수영 , 정용환 , 이욱재 , 김지영 , 이정아 , 윤원종 , 오대주
IPC分类号： A61K36/47 , A61P39/06 , A61P31/04 , A61P29/00
CPC分类号： A61K36/47 , A23V2200/02 , A23V2200/302 , A61K2236/15 , A61K2236/17 , A61K2236/333 , Y10S514/886
摘要： A composition comprising an extract of Euphorbia jolkini having excellent physiological activity is provided to secure excellent anti-oxidizing, anti-inflammatory and antibacterial activities. A composition comprises an extract of Euphorbia jolkini. The extract is obtained by crushing Euphorbia jolkini dried in the shade using a mill, precipitating the obtained fine powder in ethanol and extracting it using ultrasonic wave three times per one hour, concentrating recovered supernatant of the extract under reduced pressure, suspending the concentrate in water, and extracting the suspension with hexane, dichloromethane, ethylacetate and butanol in sequence.
摘要翻译：提供包含具有优异生理活性的大戟科提取物的组合物以确保优异的抗氧化，抗炎和抗菌活性。组合物包含大戟草提取物。提取物是通过使用研磨机在阴凉处破碎的大戟捣碎获得的，将得到的细粉末在乙醇中沉淀并用超声波将其每小时提取三次，减压浓缩萃取液的回收上清液，将浓缩物悬浮于水中并依次用己烷，二氯甲烷，乙酸乙酯和丁醇萃取悬浮液。

5. 发明授权

KR101162761B1 비만 예방 또는 치료용 조성물 有权
标题翻译：用于预防或治疗肥胖的组合物
公开(公告)号：KR101162761B1
公开(公告)日：2012-07-05
申请号：KR1020080007278
申请日：2008-01-23
申请人： 재단법인 제주테크노파크
发明人： 김기옥 , 한종헌 , 고광효 , 이정아 , 김행범 , 강민철 , 이주엽 , 김봉석 , 진호경 , 안승현 , 진희철
IPC分类号： A61K31/35 , A61K31/352 , A61K36/752 , A61P3/04
摘要： 본 발명은 비만 예방 또는 치료용 조성물에 관한 것으로, 구체적으로는 미성숙 감귤 추출물 또는 이로부터 분리한 리모시트린-3-글루코즈(limocitrin-3-glucose), 8-메톡시 퀘르세틴 3-오-[6”-(3”′-하이드록시-3”′-메틸-글루타로일)-베타-디-글루코피라노시드] (8-Methoxy Quercetin 3-
O -[6”-(3”'-hydroxy-3”'-methyl-glutaroyl)-
β -D-glucopyranoside]), 퀘르세틴3-오-[6”-(3”′-하이드록시-3”′-메틸-글루타로일)-베타-디-글루코피라노시드] (Quercetin 3-
O -[6”-(3”'-hydroxy-3”'-methyl-glutaroyl)-
β -D-glucopyranoside]) 및 5,6,7,8,3',4'-헥사메톡시퀘르세틴3-오-[6”-(3”'-하이드록시-글루타로일)-베타-디-글루코피라노시드](5,6,7,8,3',4'-HexaMethoxyQuercetin3-O-[6”-(3”'-hydroxy-3”'-methyl-glutaroyl)-β-D-glucopyranoside])로 이루어진 군으로부터 선택된 하나 이상의 화합물을 포함하는 비만 예방 또는 치료용 조성물에 관한 것이다. 또한, 본 발명은 상기 비만 예방 또는 치료용 조성물을 포함하는 약제학적 조성물 및 건강 기능성 식품에 관한 것이다.
온주밀감, 미성숙과, 비만

6. 发明公开

KR1020080020738A 항염활성 및 골대사 관련인자 억제활성을 나타내는까마귀쪽나무 추출물 有权
标题翻译：具有抗炎活性和骨代谢因子抑制活性的LITSEA JAPONICA提取物
公开(公告)号：KR1020080020738A
公开(公告)日：2008-03-06
申请号：KR1020060083944
申请日：2006-09-01
申请人： 재단법인 제주테크노파크
发明人： 박수영 , 정용환 , 윤원종 , 이정아 , 김지영 , 오대주 , 유은숙 , 이혜자
IPC分类号： A61K36/54 , A61P39/06
CPC分类号： A61K36/54 , A23V2200/304 , A61K2236/33 , Y10S514/825
摘要： A composition comprising the extract of Litsea japonica is provided to prevent and treat inflammatory disease and metabolic bone disease including osteoporosis and osteopetrosis by inhibiting inflammation and bone metabolic factors including IL-6(interleukin-6), COX-2(cyclooxygenase-2) and PGE2(prostaglandin E2) without side effects. A composition for preventing and treating inflammatory disease and metabolic bone disease comprises the extract of Litsea japonica which is prepared by drying leaf, stem or fruit of Litsea japonica juss in the shade, pulverizing the dried Litsea japonica juss, dipping the pulverized Litsea japonica juss in 80% ethanol, sonicating the Litsea japonica juss solution for 1 hour, repeating the sonication in three times to prepare the ethanol extract of Litsea japonica juss, collecting the supernatant and concentrating the supernatant under reduced pressure, suspending the concentrate in distilled water, and extracting the suspension with hexane, dichloromethane, ethyl acetate and butanol sequentially, and is formulated as food additives or drink.
摘要翻译：提供包含日本蓟马提取物的组合物，通过抑制炎症和包括IL-6（白细胞介素-6），COX-2（环氧合酶-2）和骨质疏松素-2）在内的骨代谢因子来预防和治疗包括骨质疏松和骨质疏松的炎性疾病和代谢性骨病， PGE2（前列腺素E2）无副作用。用于预防和治疗炎性疾病和代谢性骨疾病的组合物包括通过在树荫下干燥荔枝枣的叶，茎或果实制备的荔枝提取物，粉碎干燥的枸杞，将粉碎的荔枝粳稻 80％乙醇，将Litsea japonica juss溶液超声处理1小时，三次重复超声处理，制备日本it杷的乙醇提取物，收集上清液，减压浓缩上清液，将浓缩物悬浮于蒸馏水中，萃取依次用己烷，二氯甲烷，乙酸乙酯和丁醇悬浮，配制成食品添加剂或饮料。

7. 发明公开

KR1020080020736A 항산화활성 및 골대사 관련인자 억제활성을 나타내는청동풍뎅이 추출물 失效
标题翻译：具有抗氧化活性和骨代谢因子抑制活性的异马隆阿尔卑斯提取物
公开(公告)号：KR1020080020736A
公开(公告)日：2008-03-06
申请号：KR1020060083942
申请日：2006-09-01
申请人： 재단법인 제주테크노파크
发明人： 박수영 , 정용환 , 이정아 , 윤원종 , 김지영 , 오대주 , 김상범 , 이가은 , 전형식
IPC分类号： A61K35/64 , A61K9/14
CPC分类号： A61K9/14 , A61K35/63
摘要： A composition comprising the extract of Anomala albopilosa is provided to inhibit oxidation, inflammation and bone metabolism factors, so that the composition is useful for prevention and treatment of diseases caused by oxidation, inflammation and bone metabolism disorders including cancer, inflammation, arteriosclerosis, liver disease, rheumatoid arthritis, osteoporosis and osteopetrosis. A composition for preventing and treating diseases caused by oxidation, inflammation and bone metabolism factors comprises the extract of Anomala albopilosa which is prepared by drying imago or larva of Anomala albopilosa in the shade, pulverizing the dried Anomala albopilosa, dipping the dried Anomala albopilosa in 80% ethanol, and extracting the solution with ultrasonic wave in three times for 1 hour in each time, and has at least one effect selected from DPPH(diphenylpicrylhydrazyl) radical removal, xanthine oxidase inhibition, superoxide radical removal and nitric oxide production inhibition.
摘要翻译：提供了包含Anomala albopilosa的提取物的组合物以抑制氧化，炎症和骨代谢因子，使得该组合物可用于预防和治疗由氧化，炎症和骨代谢障碍引起的疾病，包括癌症，炎症，动脉硬化，肝脏疾病，类风湿性关节炎，骨质疏松症和骨硬化症。用于预防和治疗由氧化，炎症和骨代谢因素引起的疾病的组合物包括通过在阴凉处干燥成虫或黑僵菌的成虫或幼虫制备的黑马的提取物，粉碎干燥的阿诺玛菌（Anomala albopilosa），将干燥的阿诺玛拉（Anomala albopilosa）浸入80 ％乙醇，每次用超声波提取溶液3次，每次1小时，并具有至少一种选自DPPH（二苯基丙基酰肼基）自由基去除，黄嘌呤氧化酶抑制，超氧自由基去除和一氧化氮生成抑制作用。

8. 发明公开

KR1020110027856A 신장 증가용 조성물 无效
标题翻译：用于增加身体高度的组合物
公开(公告)号：KR1020110027856A
公开(公告)日：2011-03-17
申请号：KR1020090082975
申请日：2009-09-03
申请人： 재단법인 제주테크노파크 , 농업회사법인 제주마산업 주식회사
发明人： 강대평 , 박수영 , 최한 , 김동희 , 오승현 , 변지언 , 함영민 , 윤원종 , 김길남 , 강세찬 , 김윤정 , 이정아
IPC分类号： A61K35/32 , A23L33/00 , A23L2/52
CPC分类号： A61K35/32 , A23L2/52 , A23L33/105 , A23L33/00
摘要： PURPOSE: A composition containing horse bone for increasing height is provided to prevent and treat dwarfism. CONSTITUTION: A composition for increasing height contains horse bone extract. The horse bone extract is obtained by isolating with methanol, ethanol, acetone, ethyl acetate, saturated normal butanol, chloroform, methylene chloride, water, or mixture solvent thereof. The composition further contains deer antlet powder or extract, Cibotii Rhizoma powder or extract, and Acanthopanacis Cortex powder or extract. The composition is a food composition, beverage.
摘要翻译：目的：提供含有增加高度的马骨的组合物，以预防和治疗侏儒症。构成：增加高度的组合物含有马骨提取物。通过用甲醇，乙醇，丙酮，乙酸乙酯，饱和正丁醇，氯仿，二氯甲烷，水或其混合溶剂分离得到马骨提取物。所述组合物还含有鹿茸粉或提取物，Cibotii Rhizoma粉或提取物，以及刺五加皮质粉或提取物。组合物是食物组合物，饮料。

9. 发明公开

KR1020090104519A 송악 추출물을 함유하는 미백 화장료 조성물 无效
标题翻译：化妆品组合物，用于包含HEDERA RHOMBEA的提取物的皮肤白化
公开(公告)号：KR1020090104519A
公开(公告)日：2009-10-06
申请号：KR1020080029970
申请日：2008-03-31
申请人： 재단법인 제주테크노파크
发明人： 김기옥 , 한종헌 , 고광효 , 이정아 , 김행범 , 강민철 , 이주엽 , 김봉석 , 고영국 , 진호경 , 안승현 , 진희철 , 이건국 , 이강태
IPC分类号： A61K8/97 , A61Q19/02
CPC分类号： A61K8/97 , A61K36/25 , A61Q19/02 , Y10S514/844
摘要： PURPOSE: A whitening cosmetic composition containing Rhombea extract is provided to suppress melanogenesis and tyrosinase activity and prevent skin aging. CONSTITUTION: A method for manufacturing Rhombea extract with activity of melanogenesis and inhibiting tyrosinase comprises: a step of washing Rhombea; a step of drying and pulverizing the Rhombea; a step of dropping organic solvent and filtering; a step of concentrating filtering liquid to obtain powder; and a step of fractioning the Rhombea extract with organic solvent.
摘要翻译：目的：提供含有Rhombea提取物的美白化妆品，以抑制黑素生成和酪氨酸酶活性，并防止皮肤老化。构成：制造具有黑色素生成活性和抑制酪氨酸酶活性的菱形提取物的方法，包括：洗涤菱角的步骤; 干燥和粉碎罗汉亚的一个步骤; 滴加有机溶剂并过滤的步骤; 浓缩过滤液以获得粉末的步骤; 和用有机溶剂分级罗氏提取物的步骤。

10. 发明公开

KR1020090081287A 비만 예방 또는 치료용 조성물 有权
标题翻译：用于预防或治疗肥胖的组合物
公开(公告)号：KR1020090081287A
公开(公告)日：2009-07-28
申请号：KR1020080007278
申请日：2008-01-23
申请人： 재단법인 제주테크노파크
发明人： 김기옥 , 한종헌 , 고광효 , 이정아 , 김행범 , 강민철 , 이주엽 , 김봉석 , 진호경 , 안승현 , 진희철
IPC分类号： A61K31/35 , A61K31/352 , A61K36/752 , A61P3/04
摘要： A composition for preventing and treating obesity is provided to reduce the content of cholesterol and neutral lipid in blood and effectively prevent and treat obesity by reducing weight. A composition for preventing or treating obesity comprises a citrus extract or compound of the chemical formulas 1 to 4 isolated from the extract. The citrus extract is contained in 0.01 to 50 weight% based on the weight of total composition. The compound is contained in 0.001 to 50 weight% based on total weight.
摘要翻译：提供了用于预防和治疗肥胖症的组合物，以减少血液中胆固醇和中性脂质的含量，并通过减轻重量来有效预防和治疗肥胖。用于预防或治疗肥胖症的组合物包括从提取物中分离的柑橘提取物或化学式1至4的化合物。基于总组合物的重量，柑橘提取物的含量为0.01至50重量％。该化合物的含量占总重量的0.001〜50重量％。

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