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1. 发明公开

KR1020030050821A 알코올 흡수 억제용 두릅 추출물 및 이의 제조방법 失效
标题翻译：具有增强酒精吸收抑制活性的ARALIA ELATA萃取组合物及其生产
公开(公告)号：KR1020030050821A
公开(公告)日：2003-06-25
申请号：KR1020010081348
申请日：2001-12-19
申请人： 씨제이 주식회사
发明人： 함태진 , 강희철 , 강진아 , 조희재 , 연규정 , 김달현 , 최재묵
IPC分类号： A61K36/25 , A61P25/32
摘要： PURPOSE: A method of preparing an Aralia elata(Miq.) Seem. extract composition by extracting Aralia elata(Miq.) Seem. and then subjecting the extract to hydrolysis treatment under basic conditions is provided. Thus obtained extract has excellent alcohol absorption inhibiting effect. CONSTITUTION: The leaf, sprout, bark or skin of Aralia elata(Miq.) Seem. is ground, dried and extracted. Thereafter, the extract is subjected to hydrolysis treatment in a heating and pressure device such as an autoclave and the hydrolysate is neutralized by acid treatment. For an example, 1kg Aralia elata(Miq.) Seem. powder is extracted in 20L water for about 6hr and concentrated to produce 2,000ml of an extract having a solid content of 10%. And 500ml of the extract is added with 0.1N NaOH, heated at 120deg.C for 30min and neutralized with 0.1N HCl.
摘要翻译：目的：制备一种Aralia elata（Miq。）的方法。通过提取Aralia elata（Miq。）提取物组合物。然后提供在碱性条件下进行水解处理。这样得到的提取物具有优异的酒精吸收抑制作用。构成：Aralia elata（Miq。）的叶，芽，树皮或皮肤似乎。被磨碎，干燥并提取。然后，在高压釜等加热和加压装置中进行水解处理，并通过酸处理将水解产物中和。例如，1kg Aralia elata（Miq。）似乎。粉末在20L水中萃取约6小时，浓缩，得到2000ml固含量为10％的提取物。加入500ml萃取液，加入0.1N NaOH，120℃加热30min，用0.1N HCl中和。

2. 发明公开

KR1020030052860A 섬수 정제 엑스 및 인삼 정제 엑스를 함께 함유하면서다른 정유 생약 성분은 함유하지 않는 조루증의 예방 및치료용 조성물 有权
标题翻译：含有防腐和预处理原料的芬松提取物和金松提取物的组合物
公开(公告)号：KR1020030052860A
公开(公告)日：2003-06-27
申请号：KR1020010082978
申请日：2001-12-21
申请人： 씨제이 주식회사
发明人： 강진아 , 함태진 , 강희철 , 조희재 , 김영훈 , 정성학
IPC分类号： A61K35/65 , A61K36/258 , A61K9/06
CPC分类号： A61K36/258 , A61K35/65 , A61K9/06 , A61K2236/39
摘要： PURPOSE: A composition containing a Bufonis venenum extract and a ginseng extract without other essential oils is provided. The composition inhibits smooth muscle contraction of bufodienolide as a medicinal component of Bufonis venenum thus prolongs the duration of sexual intercourse while reducing adverse effect such as erectile dysfunction. CONSTITUTION: A pharmaceutical composition for prevention and treatment of premature ejaculation contains 0.01 to 3% by weight of a Bufonis venenum extract and 0.01 to 5% by weight of a ginseng extract containing saponin as a main ingredient without other essential oils, based on the total weight of the composition. The Bufonis venenum extract is obtained by extracting in one or more solvents selected from the group consisting of ethylacetate, dichloromethane and chloroform. The ginseng extract is obtained by extracting in ethanol and then subjecting to solvent fraction or column chromatography.
摘要翻译：目的：提供含有芦苇提取物和不含其他精油的人参提取物的组合物。该组合物抑制作为维生素A的药用成分的蟾毒多烯醇的平滑肌收缩，从而延长性交的持续时间，同时减少勃起功能障碍等不利影响。构成：用于预防和治疗早泄的药物组合物含有0.01至3重量％的芦苇提取物和0.01至5重量％的含有皂苷作为主要成分而不含其他精油的人参提取物，基于总计组合物的重量。通过在一种或多种选自乙酸乙酯，二氯甲烷和氯仿中的溶剂中萃取来获得蟾蜍提取物。人参提取物通过在乙醇中萃取，然后进行溶剂级分或柱色谱法获得。

3. 发明公开

KR1020020006895A 두릅나무 추출물을 함유한 숙취방지용 조성물 无效
标题翻译：包含ARALIA ELATA SEEM萃取物的防范组合物
公开(公告)号：KR1020020006895A
公开(公告)日：2002-01-26
申请号：KR1020000040413
申请日：2000-07-14
申请人： 씨제이 주식회사
发明人： 함태진 , 강기신 , 최재묵 , 이성학 , 김달현 , 연규정 , 조희제
IPC分类号： A23L2/38
摘要： PURPOSE: Provided is a Hangover-preventing composition which contains extract of Aralia elata SEEM, as an active ingredient, thus decreases blood ethanol concentration, removes alcohol's effects on stomach stimulation to prevent or reduce hangover. CONSTITUTION: The composition for the prevention of hangover contains 1-50 wt.%, preferably 1-30 wt.% of the extract of Aralia elata SEEM, as an active ingredient. It can be formulated into suspension, capsules, tablets and powders by using an appropriate diluent, or added to foods.
摘要翻译：目的：提供含有Aralia elata SEEM的提取物作为活性成分的防宿醉剂组合物，从而降低血液乙醇浓度，消除酒精对胃刺激的作用，以预防或减少宿醉。构成：用于预防宿醉的组合物含有1-50重量％，优选1-30重量％的Aralia elata SEEM提取物作为活性成分。它可以通过使用适当的稀释剂配制成悬浮液，胶囊，片剂和粉剂，或加入到食品中。

4. 发明公开

KR1020000040012A 퀴놀론계항균화합물의주사또는주입용수용액제제 失效
标题翻译：用于注射的喹诺酮类抗生素化合物的水溶液制备
公开(公告)号：KR1020000040012A
公开(公告)日：2000-07-05
申请号：KR1019980055541
申请日：1998-12-14
申请人： 씨제이 주식회사
发明人： 함태진 , 연규정 , 온윤성 , 김제학
IPC分类号： A61K31/44 , A61K9/08
摘要： PURPOSE: A pharmaceutically stable aqueous preparation for injection contains the hydrochloric acid salt of the compound of formula(1) as an antibacterial element and mannitol as stabilizer. CONSTITUTION: A stable aqueous preparation for non-oral administration comprises 0.01-20 w/v% of hydrochloric acid salt of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(£1alpha,5alpha,6beta|6-amino-1 -methyl-3-azabicyclo£3.3.0|heptane-3-yl)-1,8-naphtylidine-3-carboxylate (formula(1)), 0.01-20 w/v% of mannitol and water for injection as a solvent. The pH of the preparation is 2.0-7.0, desirably 3.0-5.0.
摘要翻译：目的：药学上稳定的注射用含水制剂含有作为抗菌元件的式（1）化合物的盐酸盐和作为稳定剂的甘露糖醇。构成：用于非口服给药的稳定的水性制剂包含0.01-20w / v％的1-环丙基-6-氟-1,4-二氢-4-氧代-7-（1α，5α， 6beta | 6-氨基-1-甲基-3-氮杂双环{3.3.0 |庚烷-3-基）-1,8-二氮杂环丁烷-3-羧酸酯（式（1）），0.01-20w / v％的甘露醇和注射用水作为溶剂。制剂的pH为2.0-7.0，理想的为3.0-5.0。

5. 发明授权

KR100462329B1 알코올 흡수 억제용 두릅 추출물 및 이의 제조방법 失效
标题翻译： 알코올흡수억제용두릅출물및이의제조방법
公开(公告)号：KR100462329B1
公开(公告)日：2004-12-17
申请号：KR1020010081348
申请日：2001-12-19
申请人： 씨제이 주식회사
发明人： 함태진 , 강희철 , 강진아 , 조희재 , 연규정 , 김달현 , 최재묵
IPC分类号： A61K36/25 , A61P25/32
摘要： PURPOSE: A method of preparing an Aralia elata(Miq.) Seem. extract composition by extracting Aralia elata(Miq.) Seem. and then subjecting the extract to hydrolysis treatment under basic conditions is provided. Thus obtained extract has excellent alcohol absorption inhibiting effect. CONSTITUTION: The leaf, sprout, bark or skin of Aralia elata(Miq.) Seem. is ground, dried and extracted. Thereafter, the extract is subjected to hydrolysis treatment in a heating and pressure device such as an autoclave and the hydrolysate is neutralized by acid treatment. For an example, 1kg Aralia elata(Miq.) Seem. powder is extracted in 20L water for about 6hr and concentrated to produce 2,000ml of an extract having a solid content of 10%. And 500ml of the extract is added with 0.1N NaOH, heated at 120deg.C for 30min and neutralized with 0.1N HCl.
摘要翻译：目的：一种方法准备龙牙草（Miq。）似乎。通过提取龙牙草（Miral。）提取组合物。然后在碱性条件下对提取物进行水解处理。这样得到的提取物具有优异的酒精吸收抑制作用组成：Aralia elata（Miq。）的叶，芽，树皮或皮肤。被磨碎，干燥并提取。之后，将提取物在加热加压装置如高压釜中进行水解处理，并通过酸处理中和水解产物。例如，1公斤Aralia elata（Miq。），见。粉末在20L水中提取约6小时并浓缩以产生2,000ml固含量为10％的提取物。向500ml提取物中加入0.1N NaOH，在120℃加热30分钟，并用0.1N HCl中和。

6. 发明授权

KR100517637B1 섬수 정제 엑스 및 인삼 정제 엑스를 함께 함유하면서다른 정유 생약 성분은 함유하지 않는 조루증의 예방 및치료용 조성물 有权
标题翻译：用于不含其他必需油的包装和金松净化提取物的预处理和预处理预处理组合物
公开(公告)号：KR100517637B1
公开(公告)日：2005-09-28
申请号：KR1020010082978
申请日：2001-12-21
申请人： 씨제이 주식회사
发明人： 강진아 , 함태진 , 강희철 , 조희재 , 김영훈 , 정성학
IPC分类号： A61K35/65 , A61K36/258 , A61K9/06
CPC分类号： A61K36/258
摘要： 본 발명은 섬수 정제 엑스 및 사포닌을 주성분으로 한 인삼 정제 엑스를 함께 함유하면서 다른 정유 생약 성분은 함유하지 않는 것을 특징으로 하는 조루증의 예방 및 치료용 조성물에 관한 것이다.

7. 发明授权

KR100473963B1 퀴놀론계항균화합물의주사또는주입용수용액제제 失效
标题翻译：用于注射或输注喹诺酮抗生素的水溶液
公开(公告)号：KR100473963B1
公开(公告)日：2005-08-02
申请号：KR1019980055541
申请日：1998-12-14
申请人： 씨제이 주식회사
发明人： 함태진 , 연규정 , 온윤성 , 김제학
IPC分类号： A61K31/44 , A61K9/08
摘要： 본 발명은 하기 화학식(I)로 표시되는 공지의 퀴놀론계 항균화합물인 1-사이클로프로필-6-플루오르-1,4-디하이드로-4-옥소-7-([1α ,5α ,6β ]6-아미노-1-메틸-3-아자바이사이클로[3.3.0]헵탄-3-일)-1,8-나프티리딘-3-카르복실산의 염산염을 안정화제로서 만니톨과 함께 함유하여 액체상태로 매우 안정하며 비경구적으로 투여 가능한 제약학적 수용액 제제에 관한 것이다:

8. 发明授权

KR100314405B1 의약품비드제조장치및제조방법 失效
标题翻译：药物珠制造装置和制造方法
公开(公告)号：KR100314405B1
公开(公告)日：2001-12-28
申请号：KR1019980055540
申请日：1998-12-14
申请人： 씨제이 주식회사
发明人： 온윤성 , 김성남 , 함태진 , 연규정 , 김제학
IPC分类号： A61J3/00
摘要： 본 발명은 항생제 등 열에 불아정한 의약품을 함유하는 의약품 비드를 대량으로 제조하기 위한 장치 및 이 장치를 이용하여 의약품 비드를 제조하는 방법에 관한 것인 바, 기존의 비드 제작 방법의 단점을 보완하여 의약품, 의료용 시멘트 및 액체 모노머를 혼합하고 성형하는 공정을 낮은 온도에서 시행하는 방법을 통해 고화에 걸리는 시간을 24시간 이상 연장시켜 다량의 비드 제조에 충분한 시간을 얻었으며, 사출기의 노즐 직경을 최종 비드 직경과 동일하게 하여 혼합물의 점도가 높은 경우에도 분말과 액체의 상분리가 일어나지 않게 하고, 플라스틱 재질의 구상체 주형을 사용하여 제품이 가압 롤러로부터 쉽게 분리되게 하여 가압 롤러를 세척 하지 않아도 사용이 가능하게 하여 연속적으로 비드를 생산하는 방법을 특징으로 한다.

9. 发明公开

KR1020000040011A 의약품비드제조장치및제조방법 失效
标题翻译：医疗用品的制造装置及其制造方法
公开(公告)号：KR1020000040011A
公开(公告)日：2000-07-05
申请号：KR1019980055540
申请日：1998-12-14
申请人： 씨제이 주식회사
发明人： 온윤성 , 김성남 , 함태진 , 연규정 , 김제학
IPC分类号： A61J3/00
摘要： PURPOSE: A manufacturing device of medical supplies' bead and a manufacturing method thereof are provided which are to manufacture a large quantity of the medical supplies' bead containing heat-unstable medical supplies such as antibiotic. CONSTITUTION: A device comprises: (i) a cooling injection device(1); and (ii) a bead molding device(2), wherein the cooling injection device(1) comprises: (a) a cooling portion(20) which cools a mixture of medical supplies, cement for medical treatment and liquid monomer(10); (b) a transferring portion(11) which is curved on the lower end of the cooling portion(20) and is formed as a pipe-shape; (c) a nozzle(22) which molds the mixture in fixed diameter; (d) a freezing portion(21); and (e) a cutter(30), and the bead molding device(2) comprises: (a) a container(60) which stores the cut mixture; (b) a spherical shape mold(51); (c) a pair of transferring rollers(R2, R3); and (d) a pressure roller(R1). The method comprises: (i) putting a mixture of medical supplies, cement for medical treatment and methylmethacrylate in the cooling portion; (ii) freezing the mixture; (iii) cutting the frozen mixture into fixed size; (iv) supplying the cut mixture mold to the spherical mold and pressurizing it with the pressure roller to prepare medical supplies' bead.
摘要翻译：目的：提供医疗用品珠的制造装置及其制造方法，其制造含有抗热不稳定的医疗用品如抗生素的大量医疗用品珠。构成：装置包括：（i）冷却注射装置（1）; 和（ii）珠粒成型装置（2），其中冷却注射装置（1）包括：（a）冷却医疗用品混合物，医疗用水泥和液体单体（10）的混合物的冷却部分（20）。（b）在冷却部（20）的下端弯曲并形成为管状的转印部（11）（c）将固定直径的混合物模制的喷嘴（22）; （d）冷冻部分（21）; 和（e）切割器（30），并且所述珠粒成型装置（2）包括：（a）容纳所述切割混合物的容器（60）（b）球形模具（51）; （c）一对转印辊（R2，R3）; 和（d）压力辊（R1）。该方法包括：（i）在冷却部分放置医疗用品，医用水泥和甲基丙烯酸甲酯的混合物; （ii）冷冻混合物; （iii）将冷冻混合物切成固定尺寸; （iv）将切割的混合物模具供应到球形模具并用压力辊加压，以制备医疗用品的珠粒。

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