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1. 发明公开

KR1020050037991A 자동 오염원 생물학적 병원체 검출시스템 无效
标题翻译：自动点源生物代谢检测系统
公开(公告)号：KR1020050037991A
公开(公告)日：2005-04-25
申请号：KR1020047018808
申请日：2003-05-20
申请人： 스미스 디텍션 인크. , 노드롭 그루만 코포레이션
发明人： 틸레스데이비드제이 , 디프리오,가브리엘에이. , 스미스죤씨
IPC分类号： G01N1/24 , C12Q1/00
CPC分类号： G01N35/00871 , B01L3/502 , B01L7/52 , B01L2200/10 , B01L2300/0867 , B01L2400/0487 , G01N1/10 , G01N1/2211 , G01N1/2273 , G01N1/24 , G01N1/4077 , G01N35/0099 , G01N2001/022 , G01N2001/025 , G01N2001/2217 , G01N2035/00881 , G01N2035/0436
摘要： This invention is directed to a method and apparatus using polymerase chain reaction (PCR) technology for automatically collecting air samples and identifying biological agents in the air sample. A fully automated system is provided that is capable of detecting transient events such as bacillus anthracis in a piece of mail being processed on high-speed mail processing equipment. The system includes apparatus for implementing the following features: particle collection and pre-separation using a collection hood and dry cyclone passive filtration system; continuous particle collection into a liquid sample; automated fluid transferto a PCR analysis cartridge at pre-scheduled times; automated cartridge handling and transfer to PCR bio-agent identification apparatus for detecting a bio-agent in a piece of mail; automatic retesting of the liquid sample upon various error conditions; automatic confirmation testing upon preliminary positive results; automated fluid transfer to archive containers at the completion of analysis; and, automated notification/reporting system to alert designated personnel/organizations upon the occurrence of selected events such as the presence of bacillus antracis.
摘要翻译：本发明涉及使用聚合酶链反应（PCR）技术自动收集空气样品并鉴定空气样品中的生物试剂的方法和装置。提供了一种全自动化系统，能够检测在高速邮件处理设备中处理的邮件中的瞬态事件，例如炭疽杆菌。该系统包括用于实现以下特征的装置：使用收集罩和干旋风器被动过滤系统的颗粒收集和预分离; 将连续颗粒收集到液体样品中; 以预先安排的时间自动化流体转移到PCR分析盒; 自动化处理和转移到用于检测邮件中的生物剂的PCR生物剂识别装置; 在各种错误条件下自动重新测试液体样品; 初步肯定结果自动确认测试; 在完成分析后自动化流体转移到存档容器; 以及自动通知/报告系统，以便在选定事件发生时警告指定的人员/组织，例如存在芽孢杆菌。

2. 发明公开

KR1020050084787A 오염원 생물학적 병원체 검출 시스템 无效
标题翻译：点源生物代谢检测系统
公开(公告)号：KR1020050084787A
公开(公告)日：2005-08-29
申请号：KR1020047018807
申请日：2003-05-20
申请人： 노드롭 그루만 코포레이션
发明人： 틸레스데이비드제이 , 디프리오,가브리엘에이. , 스미스죤씨
IPC分类号： C12Q1/68 , C12M1/34 , C12M3/00 , G01N1/24
CPC分类号： G01N35/00871 , B01L3/502 , B01L7/52 , B01L2200/10 , B01L2300/0867 , B01L2400/0487 , G01N1/10 , G01N1/2211 , G01N1/2273 , G01N1/24 , G01N1/4077 , G01N35/0099 , G01N2001/022 , G01N2001/025 , G01N2001/2217 , G01N2035/00881 , G01N2035/0436 , C12Q1/6844 , C12M1/34 , C12M3/00
摘要： This invention is directed to a method and apparatus using polymerase chain reaction (PCR) technologyfor collecting air samples and identifying biological agents in the air sample. The apparatus is capable ofdetecting transient events such as bacillus anthracis in a piece of mail being processed on high-speedmail processing equipment. The system includes apparatus for implementing the following features: particlecollection and pre-separation using a collection hood and dry cyclone passive filtration system; continuousparticle collection into a liquid sample; automated fluid transfer to a PCR analysis cartridge; and PCR biological identifier apparatus for detecting a bio-agent in a piece of mail following manual transport of the cartridge tothe identifier apparatus; retesting of the liquid sample upon various error conditions; confirmation testing upon preliminary positive results; fluid transfer to archive containers at the completion of analysis; and, notification/reporting system to alert designated personnel/organizations upon the occurrence of selectedevents such as the presence of bacillus anthracis.
摘要翻译：本发明涉及使用聚合酶链反应（PCR）技术来收集空气样品并鉴定空气样品中的生物制剂的方法和装置。该装置能够在高速邮件处理设备处理的邮件中检测诸如炭疽芽孢杆菌之类的瞬时事件。该系统包括用于实现以下特征的装置：使用收集罩和干旋风器被动过滤系统的粒子收集和预分离; 连续颗粒收集到液体样品中; 自动化流体转移到PCR分析盒; 以及用于在将所述盒手动传送到所述识别器装置之后检测邮件中的生物剂的PCR生物识别装置; 在各种错误条件下重新测试液体样品; 初步肯定结果确认; 在完成分析后将流体转移到档案馆; 以及通知/报告制度，以便在选定的事件发生时警告指定的人员/组织，例如炭疽芽孢杆菌的存在。

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