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1. 发明公开

KR1020080059208A 수면 호흡 장애를 예방 및 치료하는 방법과 그 수단 无效
标题翻译：预防和治疗睡眠障碍性呼吸的方法和手段
公开(公告)号：KR1020080059208A
公开(公告)日：2008-06-26
申请号：KR1020087008998
申请日：2006-09-04
申请人： 세레우사이언스 아베
发明人： 헤드너잔 , 그로테루드거 , 스텐로에프카이
IPC分类号： A61K31/16 , A61K31/137 , A61K31/424 , A61P11/00
CPC分类号： A61K31/137 , A61K31/16 , A61K31/424 , A61K31/433 , A61K31/454 , A61K31/522 , A61K31/57 , A61K31/7004
摘要： A method of treating or preventing snoring, obstructive sleep apnea (OSA) and/or central sleep apnea (CSA) comprises administering a pharmacologically effective amount a salt of acetylhomotaurine (AcHT) such as calcium acamprosate (CA) to a patient. Also disclosed is the use of AcHT and CA for the manufacture of a medicament for treating or preventing snoring, OSA and/or CSA and of a diagnostic device, kit or composition; a protective patch comprising AcHT or CA; and a pharmaceutical composition comprising AcHT or CA and an agent capable of alleviating the effects of snoring OSA and/or CSA, in combined amounts effective in the treatment of snoring OSA and/or CSA, and a carrier.
摘要翻译：治疗或预防打鼾，阻塞性睡眠呼吸暂停（OSA）和/或中枢性睡眠呼吸暂停（CSA）的方法包括向患者施用药理学有效量的乙酰高马诺酸（AcHT）的盐，例如阿坎酸钙（CA）。还公开了使用AcHT和CA来制备用于治疗或预防打鼾，OSA和/或CSA以及诊断装置，试剂盒或组合物的药物; 包括AcHT或CA的保护性贴剂; 以及包含AcHT或CA的药物组合物和能够有效治疗打鼾OSA和/或CSA以及载体的组合量的能够减轻打鼾OSA和/或CSA的作用的药剂。

2. 发明公开

KR1020080078075A 하지 불안 증후군의 치료 및 진단을 위한 방법 및 조성물 无效
标题翻译：用于治疗和诊断无症状综合症的方法和组合
公开(公告)号：KR1020080078075A
公开(公告)日：2008-08-26
申请号：KR1020087017787
申请日：2006-12-06
申请人： 세레우사이언스 아베
发明人： 그로트루드게르 , 헤드너잔 , 스텐로에프카이
IPC分类号： A61K31/48 , A61K31/428 , A61K31/198 , A61P25/00
CPC分类号： A61K31/428 , A61K31/135 , A61K31/137 , A61K31/198 , A61K31/4045 , A61K31/48 , A61K33/26 , A61K2300/00
摘要： A method of treating Restless Legs Syndrome (RLS) comprises the joint administration of an agent selected from dopamine turnover increasing agent and dopaminergic receptor exciting agent, in particular pramipexole, and iron in a biologically usable form, in pharmacologically effective combined amounts. Also disclosed is a corresponding use; a pharmaceutical composition comprising an agent selected from dopamine turnover increasing agent and dopaminergic receptor exciting agent, in particular pramipexole, and iron in a biologically usable form, and a pharmaceutically acceptable carrier; a package comprising a pharmaceutical composition for per-oral administration comprising an agent selected from dopamine turnover increasing agent and dopaminergic receptor exciting agent and a pharmaceutically acceptable carrier and a pharmaceutical composition for per-oral administration comprising iron in a biologically usable form and a pharmaceutical acceptable carrier.
摘要翻译：治疗不宁腿综合征（RLS）的方法包括以药理学有效的组合量联合施用选自多巴胺营养增加剂和多巴胺能受体激动剂（特别是普拉克索）和生物可用形式的铁的药剂。还公开了相应的用途; 药物组合物，其包含选自多巴胺营养增加剂和多巴胺能受体激动剂，特别是普拉克索，以及生物可用形式的铁和药学上可接受的载体的药剂; 一种包含用于每口服给药的药物组合物的包装，其包含选自多巴胺营养增加剂和多巴胺能受体激动剂的药剂和药学上可接受的载体和用于全口服给药的药物组合物，其包含生物可用形式的铁和药学上可接受的载体。

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