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    • 3. 发明公开
    • 어피 단백질 가수분해물을 유효성분으로 포함하는 피부 보습 및 탄력 개선용 화장료 조성물
    • 用于增湿和改善包含ALASKA POLLACK蛋白的酶水解产物的皮肤弹性的化妆品组合物
    • KR1020140073837A
    • 2014-06-17
    • KR1020120141771
    • 2012-12-07
    • 부경대학교 산학협력단
    • 김세권안별님
    • A61K8/98A61Q19/08A61Q19/00
    • A61K8/985A61K8/64A61K2800/78A61Q19/007A61Q19/08
    • The present invention relates to a cosmetic composition containing a protein hydrolysate of Alaska pollack skin as an active ingredient and, more specifically, to a cosmetic composition which has functions of moisturizing skin and improving skin elasticity and contains a protein hydrolysate of Alaska pollack skin as an active ingredient. The protein hydrolysate of Alaska pollack skin according to the present invention has safety to cause no side effects on the skin, and can maintain skin moisturizing through an antioxidant effect and improve skin elasticity through an increase in the expression of hyaluronan synthase genes. Therefore, the composition of the present invention containing the protein hydrolysate of Alaska pollack skin as an active ingredient can be used as a material for functional cosmetics for moisturizing skin and improving skin elasticity without causing skin irritation.
    • 本发明涉及一种含有阿拉斯加鳕鱼皮的蛋白质水解物作为活性成分的化妆品组合物,更具体地说,涉及具有保湿皮肤和改善皮肤弹性的作用的化妆品组合物,其含有阿拉斯加鳕鱼皮的蛋白质水解物作为 有效成分。 根据本发明的阿拉斯加鳕鱼皮的蛋白质水解物具有安全性,不会对皮肤产生副作用,并且可以通过抗氧化作用保持皮肤保湿,并通过增加透明质酸合酶基因的表达来改善皮肤弹性。 因此,含有阿拉斯加麸皮蛋白质水解物作为活性成分的本发明的组合物可以用作功能性化妆品用于保湿皮肤和改善皮肤弹性而不引起皮肤刺激的材料。
    • 10. 发明公开
    • 항산화 활성을 갖는 아미노에틸 키토올리고당
    • 具有抗氧化活性的氨基乙酰胆碱酯酶
    • KR1020100062137A
    • 2010-06-10
    • KR1020080120583
    • 2008-12-01
    • 부경대학교 산학협력단
    • 김세권김문무
    • A61K31/722A61P39/06
    • A61K31/722A23L29/30
    • PURPOSE: A pharmaceutical composition and health food of antioxication containing aminoethyl chito-oligosaccharide(AE-COS) are provided to improve COS antioxdation, to remove free radical, and to prevent activity of myeloperoxidase. CONSTITUTION: A pharmaceutical composition for antioxidation cotnains aminoethyl chito-oligosaccharides(AE-COS) of chemical formula 1 as an active ingredient. In chemical formula 1, R is (CH_2)_2NH_2, R1 is H or COCH_3, and n is 20-5,000. A health food for antioxidation contains AE-COS as an active ingredient. A method for preparing the AE-COS comprises: a step of adding chloroethylamino hydrochloride to COS; a step of dropping NaOH to reaction mixture; a step of stirring for 48 hours; a step of filtering the solution; and a step of acidifying the solution with HCl and freeze-drying.
    • 目的:提供含有氨乙乙基低聚糖(AE-COS)的抗氧化药物组合物和保健食品,以改善COS抗氧化,去除自由基,防止髓过氧化物酶的活性。 构成:化学式1的抗氧化青蒿素氨基乙基低聚半乳糖(AE-COS)作为活性成分的药物组合物。 在化学式1中,R为(CH 2)2 NH 2,R 1为H或COCH 3,n为20-5,000。 抗氧化保健食品含有AE-COS作为活性成分。 制备AE-COS的方法包括:向COS中加入氯乙基氨基盐酸盐的步骤; 将NaOH滴加到反应混合物中的步骤; 搅拌48小时的一步; 过滤溶液的一个步骤; 和用HCl酸化溶液并冷冻干燥的步骤。