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1. 发明公开

KR1020020032754A 다운증후군 관련 호르몬 측정 방법 및 측정 키트 失效
标题翻译：用于诊断下肢综合征和诊断套件的方法
公开(公告)号：KR1020020032754A
公开(公告)日：2002-05-04
申请号：KR1020000063386
申请日：2000-10-27
申请人： 김희태
发明人： 김희태 , 윤용달
IPC分类号： A61B5/145
摘要： PURPOSE: A method for diagnosing Down syndrome and a diagnosis kit thereof are provided to simultaneously analyze concentrations of four Down syndrome hormone at a space and confirm Down syndrome of a fetus fast, accurately and conveniently. CONSTITUTION: A Down syndrome diagnosis kit comprises a body(30), blood sample injecting unit(80), a second antibody storage(50) and a colorimetic indicator storage(70). The body(30) is made of transparent material has a capillary(31) branched into four tubes. The four tubes have reaction spaces(110a,120a,130a,140a) on their inner surfaces, respectively, to form an AFP analysis capillary(140) containing an antibody against the AFP, a hCG analysis capillary(130) containing an antibody against the hCG, a uE3 analysis capillary(120) containing an antibody against the uE3, and an inhibin A analysis capillary(130) containing an antibody against the inhibin A. The blood sample injecting unit(80) injects sample into the capillary(31). The second antibody storage(50) stores second antibody solution containing colorimetic enzyme to be injected into the capillary(31) for reaction with the colorimetic indicator from the colorimetic indicator storage(70).
摘要翻译：目的：提供一种诊断唐氏综合征的方法及其诊断试剂盒，以同时分析空间中四种唐氏综合征的浓度，并快速，准确，方便地确认胎儿唐氏综合征。构成：唐氏综合征诊断试剂盒包括体（30），血液注射单元（80），第二抗体储存器（50）和拟像指示剂储存器（70）。主体（30）由透明材料制成，具有分为四个管的毛细管（31）。四个管分别在其内表面上具有反应空间（110a，120a，130a，140a），以形成含有针对AFP的抗体的AFP分析毛细管（140），含有针对AFP的抗体的hCG分析毛细管（130） hCG，含有针对uE3的抗体的uE3分析毛细管（120）和含有针对抑制素A的抗体的抑制素A分析毛细管（130）。血液注射单元（80）将样品注入毛细管（31）。第二抗体储存器（50）存储含有待注射到毛细管中的拟拟酶的第二抗体溶液，用于与拟拟指示剂储存器（70）的拟拟指示剂反应。

2. 发明公开

KR1020020032753A 혈중 콜레스테롤의 농도 측정 방법 및 이를 위한 측정용키트 无效
标题翻译：用于测量血液中胆固醇浓度的方法和测量试剂盒
公开(公告)号：KR1020020032753A
公开(公告)日：2002-05-04
申请号：KR1020000063385
申请日：2000-10-27
申请人： 김희태
发明人： 김희태 , 윤용달
IPC分类号： G01N33/538
摘要： PURPOSE: A method for measuring cholesterol concentration and measuring kit for the same is provided to achieve improved accuracy of analysis result and reduce time and costs for analysis. CONSTITUTION: A method comprises a first step of mixing the blood sample with a solution, and removing blood cell by passing the mixture through a filter; a second step of injecting the blood sample into a pipe which is branched off to four capillary pipes; a third step of shifting the blood to the capillary pipes with a non-treated membrane, a membrane which is treated with an antibody with respect to a low concentration lipoprotein, a membrane which is treated with an antibody with respect to a high concentration lipoprotein, and a membrane treated with both antibodies, such that only the target lipoprotein passes through the capillary pipe by the immune reaction with antibody; a fourth step of shifting blood cell samples passed through the capillary pipe, to a membrane treated with a surface active agent, and permitting cholesterol component to be dissolved from the lipoprotein in the sample; a fifth step of shifting the solution obtained in the fourth step to membranes of each capillary pipe treated with cholesterol decomposition enzyme and color developing agent so as to permit the color developing agent to be dissolved and cholesterol to react with the enzyme; a sixth step of shifting the reaction solution to the reaction space where the enzyme for the color developing agent is fixed; and a seventh step of checking cholesterol concentration for each capillary pipe by measuring the degree of color development.
摘要翻译：目的：提供一种测定胆固醇浓度的方法和测量套件，以提高分析结果的准确性，并缩短分析的时间和成本。构成：一种方法包括将血液样品与溶液混合的第一步骤，以及通过使混合物通过过滤器去除血细胞; 将血液样本注入分支到四个毛细管的管中的第二步骤; 用未经处理的膜将血液转移到毛细管的第三步骤，用低浓度脂蛋白用抗体处理的膜，用抗体对高浓度脂蛋白进行处理的膜，和用两种抗体处理的膜，使得只有目标脂蛋白通过与抗体的免疫反应通过毛细管; 将通过毛细管的血细胞样品转移到用表面活性剂处理的膜并允许胆固醇成分从样品中的脂蛋白溶解的第四步骤; 将第四步骤中获得的溶液转移到用胆固醇分解酶和显色剂处理的每个毛细管的膜上，以使得显色剂溶解并使胆固醇与酶反应的第五步骤; 将反应溶液转移到固色用于显色剂的酶的反应空间的第六步骤; 以及通过测量显色程度来检查每个毛细管的胆固醇浓度的第七步骤。

3. 发明授权

KR100401390B1 다운증후군 관련 호르몬 측정 방법 및 측정 키트 失效
标题翻译： 다운증후군관련호르몬측정방법및측정키트
公开(公告)号：KR100401390B1
公开(公告)日：2003-10-17
申请号：KR1020000063386
申请日：2000-10-27
申请人： 김희태
发明人： 김희태 , 윤용달
IPC分类号： A61B5/145
摘要： PURPOSE: A method for diagnosing Down syndrome and a diagnosis kit thereof are provided to simultaneously analyze concentrations of four Down syndrome hormone at a space and confirm Down syndrome of a fetus fast, accurately and conveniently. CONSTITUTION: A Down syndrome diagnosis kit comprises a body(30), blood sample injecting unit(80), a second antibody storage(50) and a colorimetic indicator storage(70). The body(30) is made of transparent material has a capillary(31) branched into four tubes. The four tubes have reaction spaces(110a,120a,130a,140a) on their inner surfaces, respectively, to form an AFP analysis capillary(140) containing an antibody against the AFP, a hCG analysis capillary(130) containing an antibody against the hCG, a uE3 analysis capillary(120) containing an antibody against the uE3, and an inhibin A analysis capillary(130) containing an antibody against the inhibin A. The blood sample injecting unit(80) injects sample into the capillary(31). The second antibody storage(50) stores second antibody solution containing colorimetic enzyme to be injected into the capillary(31) for reaction with the colorimetic indicator from the colorimetic indicator storage(70).
摘要翻译：目的：提供一种诊断唐氏综合征的方法及其诊断试剂盒，用于同时分析一个空间处的四种唐氏综合征的浓度，并快速，准确和方便地确认胎儿唐氏综合征。构成：唐氏综合征诊断试剂盒包括身体（30），血液样品注射单元（80），第二抗体储存器（50）和比色指示剂储存器（70）。主体（30）由透明材料制成，具有分成四个管的毛细管（31）。四个管分别在其内表面上具有反应空间（110a，120a，130a，140a）以形成含有针对AFP的抗体的AFP分析毛细管（140），含有针对AFP的抗体的hCG分析毛细管 hCG，含有针对uE3的抗体的uE3分析毛细管（120）和含有针对抑制素A的抗体的抑制素A分析毛细管（130）。血液样品注入单元（80）将样品注入毛细管（31）中。第二抗体储存器（50）储存含有将被注入毛细管（31）中的比色学酶的第二抗体溶液，以与来自比色指示器储存器（70）的比色指示剂反应。

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