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    • 3. 发明公开
    • 민감성 피부 진단용 바이오 마커 및 이를 이용한 진단 키트
    • 用于预测敏感性皮肤和测试套件的生物标记
    • KR1020140123034A
    • 2014-10-21
    • KR1020140124120
    • 2014-09-18
    • (주)아모레퍼시픽서울대학교산학협력단
    • 안수선김수정이은영노민수이태룡문성준김한곤은희철정진호김은주최원우
    • C12Q1/68G01N33/53
    • C12Q1/6844
    • Disclosed is a biomarker of which gene expression levels are specifically increased or reduced for sensitive skin. The biomarker specific to sensitive skin is used in such a diagnostic kit for sensitive skin and a screening method of an abirritant. The biomarker for diagnosis of sensitive skin according to the present invention contains one or more gene selected from a group consisting of HLA-C, TCEA1, IGHA1, TFRC, S100A8, LOC652128, SERPINB13, EHF, FLJ10781, TP63, CDH1, TNFRSF19, GM2A, FKBP5, PI3, PSPH, HORMAD1, SPRR2G, and ACTR2 or a group consisting of KBTBD10, TTN, ACTA1, MYBPC1, MB, MYOZ1, TPM1, CA3, CASQ1, ENO3, RBP4, GYG2, PPP1R1A, PYGM, G0S2, NEB, H19, LIPE, PLIN, H19, GPAM, FABP4, CIDEC, LPL, PCK1, ADIPOQ, PDE3B, ACVR1C, LPL, FABP4, DKFZP761N09121, TNMD, ATP6V1B1, C8orf22, and CRISP3.
    • 公开了一种生物标志物,其敏感性皮肤基因表达水平被特异地增加或降低。 敏感皮肤特异性的生物标志物用于敏感皮肤的诊断试剂盒和刺激物的筛选方法。 根据本发明的敏感性皮肤诊断用生物标志物含有选自HLA-C,TCEA1,IGHA1,TFRC,S100A8,LOC652128,SERPINB13,EHF,FLJ10781,TP63,CDH1,TNFRSF19,GM2A ,FKBP5,PI3,PSPH,HORMAD1,SPRR2G和ACTR2或由KBTBD10,TTN,ACTA1,MYBPC1,MB,MYOZ1,TPM1,CA3,CASQ1,ENO3,RBP4,GYG2,PPP1R1A,PYGM,G0S2,NEB, H19,LIPE,PLIN,H19,GPAM,FABP4,CIDEC,LPL,PCK1,ADIPOQ,PDE3B,ACVR1C,LPL,FABP4,DKFZP761N09121,TNMD,ATP6V1B1,C8orf22和CRISP3。
    • 9. 发明公开
    • 민감성 피부 진단용 바이오 마커 및 이를 이용한 진단 키트
    • 用于预测敏感性皮肤和测试套件的生物标记
    • KR1020140123035A
    • 2014-10-21
    • KR1020140124122
    • 2014-09-18
    • (주)아모레퍼시픽서울대학교산학협력단
    • 안수선김수정이은영노민수이태룡문성준김한곤은희철정진호김은주최원우
    • C12Q1/68G01N33/53
    • C12Q1/6844
    • Disclosed is a biomarker of which gene expression levels are specifically increased or reduced for sensitive skin. The biomarker specific to sensitive skin is used in such a diagnostic kit for sensitive skin and a screening method of an abirritant. The biomarker for diagnosis of sensitive skin according to the present invention includes one or more genes selected from a group consisting of HLA-C, TCEA1, IGHA1, TFRC, S100A8, LOC652128, SERPINB13, EHF, FLJ10781, TP63, CDH1, TNFRSF19, GM2A, FKBP5, PI3, PSPH, HORMAD1, SPRR2G, and ACTR2 or a group consisting of KBTBD10, TTN, ACTA1, MYBPC1, MB, MYOZ1, TPM1, CA3, CASQ1, ENO3, RBP4, GYG2, PPP1R1A, PYGM, G0S2, NEB, H19, LIPE, PLIN, H19, GPAM, FABP4, CIDEC, LPL, PCK1, ADIPOQ, PDE3B, ACVR1C, LPL, FABP4, DKFZP761N09121, TNMD, ATP6V1B1, C8orf22, and CRISP3.
    • 公开了一种生物标志物,其敏感性皮肤基因表达水平被特异地增加或降低。 敏感皮肤特异性的生物标志物用于敏感皮肤的诊断试剂盒和刺激物的筛选方法。 根据本发明的敏感性皮肤诊断用生物标志物包括选自HLA-C,TCEA1,IGHA1,TFRC,S100A8,LOC652128,SERPINB13,EHF,FLJ10781,TP63,CDH1,TNFRSF19,GM2A的一种或多种基因 ,FKBP5,PI3,PSPH,HORMAD1,SPRR2G和ACTR2或由KBTBD10,TTN,ACTA1,MYBPC1,MB,MYOZ1,TPM1,CA3,CASQ1,ENO3,RBP4,GYG2,PPP1R1A,PYGM,G0S2,NEB, H19,LIPE,PLIN,H19,GPAM,FABP4,CIDEC,LPL,PCK1,ADIPOQ,PDE3B,ACVR1C,LPL,FABP4,DKFZP761N09121,TNMD,ATP6V1B1,C8orf22和CRISP3。