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    • 5. 发明公开
    • 향부자 추출물을 유효성분으로 함유하는 지방간 치료 또는 예방용 약학조성물
    • 用于治疗或预防包含CYPERI RHIZOMA提取物的脂肪肝疾病的药物组合物
    • KR1020120118736A
    • 2012-10-29
    • KR1020110036298
    • 2011-04-19
    • 울산대학교 산학협력단주식회사 고암바이오알앤디수
    • 김승환곽종환오균식
    • A61K36/8905A61P1/16A61P1/00
    • PURPOSE: A pharmaceutical composition for treating and preventing steatosis which contains cyperi rhizoma extracts is provided to obstruct inter-combination between LSR and TRAP80. CONSTITUTION: A pharmaceutical composition for treating and preventing steatosis contains cyperi rhizoma extracts. The steatosis is alcohol steatosis or vial call steatosis. The cyperi rhizoma suppresses lipogenesis by controlling inter-combination between TRAP80 and LXR. The cyperi rhizoma extract selectively controls transcription of SREBP-1c. The cyperi rhizoma extract is extracted with C1-4 alcohol, hexane, cychlohexan, methylene chloride, chloroform, ether(ethyl ether), ethyl acetate, water or a mixed solvent thereof. The cyperi rhizoma extract is obtained by the following steps: extracting the cyperi rhizoma with methanol or ethanol; suspending the methanol or ethanol extract in distilled water; adding identical amount of hexane as distilled water and partitioning thereof.
    • 目的:提供含有铁杆菌提取物的治疗和预防脂肪变性的药物组合物,以阻止LSR和TRAP80之间的组合。 构成:用于治疗和预防脂肪变性的药物组合物含有萤石提取物。 脂肪变性是酒精脂肪变性或小瓶呼吸脂肪变性。 Cyperi根茎通过控制TRAP80和LXR之间的组合来抑制脂肪生成。 仙人掌提取物选择性控制SREBP-1c的转录。 提取物用C 1-4醇,己烷,环己烷,二氯甲烷,氯仿,乙醚,乙酸乙酯,水或其混合溶剂萃取。 通过以下步骤获得苦参提取物:用甲醇或乙醇萃取桂皮; 将甲醇或乙醇提取物悬浮于蒸馏水中; 加入等量的己烷作为蒸馏水并分配。