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    • 23. 发明公开
    • 초본식물, 시스탄체 투부로사(스첸크) 위그트로부터추출되는 페닐에타노이드 글리코시드를 함유하는 의약제제, 그것의 제조방법, 및 그것의 사용
    • 生产含有从支链淀粉(SCHENK。)提取的苯乙酸甘油酯的药物制剂具有提高记忆效能,预防先天性和抑制血小板聚集的优异疗效
    • KR1020040074614A
    • 2004-08-25
    • KR1020040010530
    • 2004-02-18
    • 신파 파마세우티컬 코리미티드
    • 투펭페이송지홍레이리
    • A61K36/64A61K31/70A61K31/7028
    • A61K36/64A61K31/70A61K31/7028A61K2300/00
    • PURPOSE: A method of making a pharmaceutical preparation containing phenylethanoid glycosides extracted from Cistanche tubulosa(schenk.) wight is provided. The pharmaceutical preparation has excellent efficacy on enhancing memory, preventing senile dementia and inhibiting platelet aggregation. CONSTITUTION: The pharmaceutical preparation contains phenylethanoid glycosides extracted from Cistanche tubulosa(schenk.) wight. The phenylethanoid glycosides comprise 10 to 70% by weight of echinacoside, 1 to 40% by weight of acteoside and additionally 5% or less by weight of 2'-acetylacteoside, campneoside I, campneoside II, crenatoside, isoacteoside, syringalide A, 3'-α-L-rhamnopyranoside and tubuloside A. The phenylethanoid glycosides are obtained by: extracting Cistanche tubulosa(schenk.) wight in water or a mixture of water and ethanol; introducing the extract into a column filled with hydrophilic polymer beads; subjecting the column to an elution process with water; and then subjecting the column to an elution process with a mixture of water and ethanol.
    • 目的:提供一种制备含有从肉istan蓉(schenk。)提取的苯乙醇苷的药物制剂的方法。 该药物制剂对于增强记忆力,预防老年痴呆和抑制血小板聚集具有优异的疗效。 构成:药物制剂含有从肉istan蓉(schenk。)提取的苯乙醇苷。 苯乙醇糖苷包含10至70重量%的松果菊苷,1至40重量%的肌动蛋白,另外5重量%或更少的2'-乙酰乳糖苷,camp ne苷I,camp蛇苷II,胭脂虫苷,异睾酮, -α-L-鼠李糖苷和tubuloside A.苯乙醇糖苷通过以下方法获得:在水中或水与乙醇的混合物中提取肉istan蓉(schenk。); 将提取物引入填充有亲水性聚合物珠粒的柱子中; 使柱经水洗脱过程; 然后用水和乙醇的混合物对塔进行洗脱处理。
    • 24. 发明公开
    • 신경성장인자와 유사 작용을 갖는 육종용 추출물 및 이를함유하는 조성물
    • 具有神经生长因子活性的塞斯特林黑曲霉菌YC.MA的提取物及其组合物
    • KR1020040014757A
    • 2004-02-18
    • KR1020020047412
    • 2002-08-12
    • 경희대학교 산학협력단
    • 김선여허진영정선경
    • A61K36/64A61P25/28
    • A61K36/64
    • PURPOSE: Provided are an extract of Cistanche deserticola Y.C.MA showing enhancing activity of neurite outgrowth and neurotrophic effects and a composition containing the same. The composition is effective for protection of nerve cells and prevention and treatment of degenerative brain diseases. CONSTITUTION: A crude extract of Cistanche deserticola Y.C.MA has nerve growth factor like activities, such as increase of the growth of nerve, inhibition of nerve cell apoptosis and regeneration of damaged nerve cells. A composition for protection of nerve cells and prevention and treatment of degenerative diseases comprises the crude extract and its polar or non-polar solvent extract, wherein the polar solvent includes water, methanol, butanol or their mixture and the non-polar solvent includes hexane, chloroform, and ethylacetate.
    • 目的:提供肉istan蓉沙拉霉素Y.C.MA的提取物,其显示出神经突向外生长和神经营养作用的增强活性和含有它们的组合物。 该组合物有效保护神经细胞,预防和治疗退行性脑疾病。 构成:肉istan蓉的粗提物Y.C.MA具有神经生长因子活性,如神经生长增加,神经细胞凋亡抑制和受损神经细胞再生。 用于保护神经细胞和预防和治疗退行性疾病的组合物包括粗提物及其极性或非极性溶剂提取物,其中极性溶剂包括水,甲醇,丁醇或其混合物,非极性溶剂包括己烷, 氯仿和乙酸乙酯。
    • 25. 发明公开
    • 스태미나 증진효과가 있는 천연차 및 그 제조방법
    • 自然谷物增加STAMINA及其制作方法
    • KR1020010018592A
    • 2001-03-05
    • KR1019990034615
    • 1999-08-20
    • 남종현
    • 남종현
    • A23F3/00
    • A23F3/34A61K36/185A61K36/23A61K36/64A61K36/69A61K36/79A61K36/80A61K2300/00
    • PURPOSE: A nourishing natural tea is provided, which is made from an extract of parasitic plant for breeding and Alnus japonica(alder) or Schizandra chinensis BAILL efficacious in building physical vigor and stamina increasing body's efficiency. CONSTITUTION: The natural tea composition comprises 20-80wt% of a parasitic plant as a first ingredient and 20-80wt% of leaves, root and trunk of the alder or Schizandra chinensis BAILL. as a second ingredient and 10-70wt% of leaves, root and trunk of milkwort and Torilis japonica can be optionally added to the composition. The herb compound containing 10-20wt% of water respectively can be cut into fine pieces and hot air dried or naturally dried before mixed up, mixed, cut into pieces and pulverized, or cut, steamed and dried. The sliced herbal materials can be extracted to a herb liquid by using ethanol or water.
    • 目的:提供一种滋养天然茶,由寄生植物提取物和Al)(al der)或五味子五味子BAILL提供有效的身体活力和体力提高身体的效率。 构成:天然茶组合物含有20-80重量%的寄生植物作为第一成分,20-80重量%的al子或五味子五味子的叶,根和树干。 作为第二成分和10-70重量%的叶子,可以任选地在组合物中加入甘草和茯苓的根和干。 含有10-20%(重量)水的草本化合物可以切割成细片,热风干燥或自然干燥,然后混合,混合,切成片并粉碎,切割,蒸和干燥。 通过使用乙醇或水可将切片的草药材料提取成草药液。
    • 29. 发明公开
    • 염증성 장질환의 예방 또는 치료효과를 갖는 약학 조성물
    • 用于预防或治疗炎症性皮肤疾病的药物组合物
    • KR1020140004933A
    • 2014-01-14
    • KR1020120072390
    • 2012-07-03
    • 경희대학교 산학협력단
    • 김진주고은정이의정
    • A61K36/8965A61K36/539A61K36/79A61P29/00
    • A61K38/204A61K35/618A61K36/539A61K36/64A61K36/65A61K36/73A61K36/736A61K36/738A61K36/79A61K36/804A61K36/84A61K36/8965A61K36/904A61K38/19A61K38/191A61K38/2006A61K2300/00
    • The present invention relates to a pharmaceutical composition containing the extract of a mixture of Stemona japonica root, Asparagus cochinchinensis Merr., Scutellaria baicalensis, Schisandra chinensis, Rehmannia glutinosa, Apricot kernel, and the bark of Paeonia suffruticosa Andrews and inhibiting the onset of inflammatory bowel disease caused by cigarette smoke, a food composition containing the same extract and preventing or overcoming the inflammatory bowel disease caused by cigarette smoke, and a method for suppressing the expression of inflammatory cytokines using the pharmaceutical composition. Since the pharmaceutical composition in the present invention contains Stemona japonica root, Asparagus cochinchinensis Merr., Scutellaria baicalensis, Schisandra chinensis, Rehmannia glutinosa, Apricot kernel, and the bark of Paeonia suffruticosa Andrews, the pharmaceutical composition decreases the expression level of MMP12, which is known to destroy the inflammatory cytokines such as IL-1β, TNF-α, IL-6, and MCP-1, elastin, and collagen, concomitant to the onset of the inflammatory bowel disease, thereby can be widely used for developing safe and effective medicine against the inflammatory bowel disease. [Reference numerals] (AA) Negative control group; (BB) Positive control group; (CC) Experimental group
    • 本发明涉及含有ona ica根,芦笋,黄芩,五味子,地黄,杏仁和安氏芍药的混合物的提取物的药物组合物,抑制炎性肠的发生 由香烟烟雾引起的疾病,含有相同提取物的食物组合物和预防或克服由香烟烟引起的炎性肠病,以及使用该药物组合物抑制炎性细胞因子表达的方法。 由于本发明的药物组合物含有ona ica根,芦笋香菇,黄芩,五味子,地黄,杏仁和芍药芍药,所以药物组合物降低MMP12的表达水平, 已知可以与炎症性肠病发病相关的炎症细胞因子如IL-1β,TNF-α,IL-6和MCP-1,弹性蛋白和胶原蛋白被破坏,从而可广泛用于开发安全有效 药物抗炎性肠病。 (附图标记)(AA)阴性对照组; (BB)阳性对照组; (CC)实验组