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    • 14. 发明公开
    • 생체막 투과성 조성물
    • 生物膜渗透性组合物
    • KR1020130027078A
    • 2013-03-14
    • KR1020120093838
    • 2012-08-27
    • (주)아모레퍼시픽
    • 장지혜김재관박진우배준호
    • A61K47/42A61K47/48C07K7/08C12N15/09
    • C07K7/08C07K2319/33
    • PURPOSE: A biological membrane permeable composition is provided to produce a carrying object substance with high vitality in high yield rate, and a composition with low molecular weight protamine combined to one end or both ends. CONSTITUTION: A biological membrane permeable composition includes a carrying object substance, and low molecular weight protamine. The low molecular weight protamine is combined to one or both ends of the carrying object substance, and has an amino acid sequence which has over 70% of homology to one or more of amino acid sequence with the amino acid sequence number 1 and the amino acid sequence number 2. The carrying object substance includes one or more selected from the group consisting of protein, polypeptide, peptide, nucleoacid, mRNA, and antisense RNA. The protein includes one selected from DKK-2(Dickkopf-related protein-2), adipokine, thrombospondin, and superoxide dismutase. The carrying object substance is one or more selected from growing factors, enzymes, hormones, transcription factors, toxin, antigen, and antibody. [Reference numerals] (AA) Concentration in cells(uM)
    • 目的:提供生物膜可渗透组合物以高产率生产具有高活力的携带物质,并将低分子量鱼精蛋白组合成一端或两端。 构成:生物膜可渗透组合物包括载体物质和低分子量鱼精蛋白。 低分子量鱼精蛋白与携带对象物质的一端或两端结合,具有氨基酸序列,其氨基酸序列与氨基酸序列号1的一个或多个氨基酸序列具有超过70%的同源性,氨基酸 载体物质包括选自蛋白质,多肽,肽,核酸,mRNA和反义RNA的一种或多种。 蛋白质包括选自DKK-2(Dickkopf相关蛋白-2),脂肪因子,血小板反应素和超氧化物歧化酶的一种。 载体物质是选自生长因子,酶,激素,转录因子,毒素,抗原和抗体中的一种或多种。 (标号)(AA)细胞浓度(uM)
    • 18. 发明公开
    • 안면 리프팅기
    • 脸部起子
    • KR1020170018171A
    • 2017-02-16
    • KR1020150111040
    • 2015-08-06
    • (주)아모레퍼시픽
    • 황정환이정인오창훈이지혜박원석한지원장지혜
    • A61N1/04A61N1/08A61B5/05
    • A45D44/22A61B5/05A61N1/04A61N1/08
    • 본발명은안면리프팅기에관한것으로, 더욱상세하게는본체외부로노출된전극을러빙하여안면골격에서피부층을유지시키는인대및 SMAS(근막)을전기적인자극(저주파영역)을줌으로써안면근육을발달/강화시키는것으로, 안면의턱ㆍ볼ㆍ이마ㆍ눈ㆍ코주변의외형(골ㆍ굴곡ㆍ평평도) 또는/및신경분포도에따라, 입체적으로다른좌표에위치하면서간격과접촉면적이다르게배치된전극들을선택적으로이용하거나자극신호의레벨(강도) 및파장을달리출력하는전극들을선택적으로이용할수 있도록하여, 사용자안면의다양한부위에따라또한각 사용자의피부상태에따라최적의마사지와리프팅이이루어지도록하는안면리프팅기에관한것이다.
    • 提升装置技术领域本发明涉及一种面部提升装置,更具体地,涉及一种面部提升装置,其中通过摩擦暴露在主体外部的电极而使面部肌肉展开/加强,从而将电刺激(低频区域)赋予 韧带和保持皮肤层在面部骨骼上的SMAS(筋膜); 本发明适于使得基于下巴,脸颊,前额,面部和/或神经分布图的外部形状(凹痕,曲率和平坦度),可以选择性地使用具有 不同的间隔和接触的表面区域,或者选择性地使用在三维不同坐标位置处输出刺激信号的不同水平(强度)和波长的电极,并且使得对用户脸部上的各个区域进行按摩和提升发生优化 或用于每个用户的皮肤状态。
    • 20. 发明公开
    • 전기 천공 장치 및 전기 천공 방법
    • 电气设备和方法
    • KR1020140035133A
    • 2014-03-21
    • KR1020120101606
    • 2012-09-13
    • (주)아모레퍼시픽
    • 박진우장지혜김재관황정환박우람이지해배준호김건형
    • A61N1/18A61N1/32A61N1/30A61M37/00
    • An electroporation device according to an embodiment of the present invention comprises: multiple electrode pins touching skin to perforate the skin; a wiring board having a wiring pattern to transmit voltage to the multiple electrode pins; a voltage generating part generating the voltage transmitted to the multiple electrode pins through the wiring pattern of the wiring board; a controlling part controlling the polarity of the voltage transmitted to the multiple electrode pins to make any neighboring electrode pins among the multiple electrode pins have different polarities in every cycle; and a voltage compensating part measuring the resistance of the skin where the multiple electrode pins touch, and compensating the voltage level transmitted to the multiple electrode pins according to the resistance level. [Reference numerals] (110) Main body; (111) Power unit; (112) Voltage generating part; (113) Controlling part; (114) Operation display part; (115) Power display part; (116) Voltage compensating part; (120) Perforating part; (121) Wiring board; (122) Electrode pin; (123) Pin guide; (130) Piezo switch
    • 根据本发明的实施例的电穿孔装置包括:多个电极针接触皮肤以穿透皮肤; 具有向多个电极引脚传输电压的布线图案的布线板; 电压产生部件,通过布线板的布线图形产生传输到多个电极引脚的电压; 控制部分控制传输到多个电极引脚的电压的极性,使得多个电极引脚中的任何相邻的电极引脚在每个周期中具有不同的极性; 以及电压补偿部,其测量多个电极引脚接触的皮肤的电阻,并根据电阻水平补偿传输到多个电极引脚的电压电平。 (附图标记)(110)主体; (111)动力单元; (112)电压产生部; (113)控制部分; (114)操作显示部分; (115)电源显示部分; (116)电压补偿部; (120)穿孔部分; (121)接线板; (122)电极针; (123)引脚引导; (130)压电开关