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    • 101. 发明公开
    • 용암해수염을 함유하는 조성물
    • 包含LAVA海水盐的组合物
    • KR1020080053614A
    • 2008-06-16
    • KR1020060125363
    • 2006-12-11
    • 에스케이바이오랜드 주식회사
    • 김기호김영희김진국김경태양홍철이수희김지연
    • A61K8/19A61K8/97A61Q19/00
    • A composition comprising lava seawater salt is provided to improve skin-moisturizing effects and skin elasticity and inhibit inflammation in the skin, so that the composition is useful for skin protection and improvement and decayed tooth prevention. A cosmetic composition comprises lava seawater salt, which is prepared by collecting lava seawater from the underground at the depth of 30-150m in Jeju island, and subjecting the collected lava seawater to sterile filtration, heat evaporation, vacuum evaporation, and sun drying or wind drying, and at least one selected from green tea, black tea, aloe, grape, banana and apple extracts, and is formulated as skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nutrition lotion, massage cream, nutrition cream, moisture cream, hand cream, foundation, essence, nutrition essence, pack, soap, cleansing foam, cleansing lotion, cleansing cream, body lotion or body cleanser. Further, the extracts are extracted by a solvent selected from polar solvent such as carbon number 1 to 4 of lower alcohol, a non-polar solvent and a mixture thereof.
    • 提供包含熔岩海水盐的组合物以改善皮肤保湿作用和皮肤弹性并抑制皮肤的炎症,使得该组合物可用于皮肤保护和改善以及衰老的牙齿预防。 化妆品组合物包括熔岩海水盐,其通过在济州岛从30-150米的地下收集熔岩海水,并将收集的熔岩海水进行无菌过滤,热蒸发,真空蒸发和晒干或风 干燥,以及选自绿茶,红茶,芦荟,葡萄,香蕉和苹果提取物中的至少一种,并配制成皮肤洗剂,皮肤柔肤剂,皮肤调色剂,收敛剂,洗剂,乳液,湿润剂,营养乳液,按摩 奶油,营养霜,防湿霜,护手霜,粉底,精华,营养精华,包装,肥皂,清洁泡沫,清洁乳液,清洁霜,身体乳液或身体清洁剂。 此外,提取物通过选自极性溶剂如低级醇的碳数1至4的非极性溶剂及其混合物的溶剂萃取。
    • 102. 发明公开
    • 저분자량 히알루론산 또는 그 염을 함유하는 조성물
    • 包含低分子量羟丙酸或其盐的组合物
    • KR1020080026924A
    • 2008-03-26
    • KR1020060092158
    • 2006-09-22
    • 에스케이바이오랜드 주식회사
    • 김기호김기수김영희김진국박선희유희종조남석
    • A61K31/728A61P17/00
    • A61K31/728A61K8/04A61K8/735A61K9/0014A61K9/06A61K9/12A61K9/7023Y10S514/886
    • A composition comprising a low molecular weight hyaluronic acid is provided to show moisturizing, wrinkle improving, wound healing and anti-inflammatory effects and be permeated into skin more easily than a high molecular weight hyaluronic acid. A composition for moisturizing, improving wrinkles, healing wound and preventing inflammation comprises a low molecular weight hyaluronic acid having a weight average molecular weight of 500-10,000 Da and represented by the formula(1) or a salt thereof as an effective ingredient. In the formula(1), n is an integer from 1 to 25; R is H, an alkali metallic salt of Li, Na, and K, an alkali earth metallic salt of Mg and Ca, ammonia, or a salt of an organic amine such as ethylene diamine, cyclohexylamine, aniline, ethanolamine, diethanolamine, triethanolamine, ethylamine, propylamine, arylamine, diethylamine, butylamine, isobutylamine, triethylamine, pentylamine, t-butylamine, and an isopropylamine. The composition is in the form of a skin external application composition such as cream, gel, patch, spray, ointment, plaster, lotion, liniment, paste type or cataplasma, or a cosmetic composition such as skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nutritive lotion, massage cream, nutritive cream, moisture cream, hand cream, foundation, essence, nutritive essence, pack, soap, cleansing foam, cleansing lotion, cleaning cream, body lotion or body cleanser.
    • 提供包含低分子量透明质酸的组合物,以显示比高分子量透明质酸更容易渗透到皮肤中的保湿,皱纹改善,伤口愈合和抗炎作用。 用于保湿,改善皱纹,愈合伤口和预防炎症的组合物包含重均分子量为500-10,000Da并由式(1)表示的低分子量透明质酸或其盐作为有效成分。 在式(1)中,n为1〜25的整数, R是H,Li,Na和K的碱金属盐,Mg和Ca的碱土金属盐,氨,或乙二胺,环己胺,苯胺,乙醇胺,二乙醇胺,三乙醇胺等有机胺的盐, 乙胺,丙胺,芳胺,二乙胺,丁胺,异丁胺,三乙胺,戊胺,叔丁胺和异丙胺。 该组合物为皮肤外用施用组合物的形式,例如霜剂,凝胶剂,贴片剂,喷雾剂,软膏剂,石膏剂,洗剂,搽剂,糊剂或粘膜,或化妆品组合物,例如皮肤润肤剂,皮肤柔肤剂, 收敛剂,乳液,乳液,保湿乳液,营养乳液,按摩霜,营养霜,护肤霜,护手霜,粉底,精华,营养精华,包装,肥皂,清洁泡沫,清洁乳液,清洁霜,身体乳液或身体清洁剂 。
    • 103. 发明公开
    • 항노화 활성을 갖는 노르베르게닌을 함유하는 피부외용조성물
    • 包含NORBERGININ显示抗衰老活性的主题组合物
    • KR1020070108786A
    • 2007-11-13
    • KR1020060041236
    • 2006-05-08
    • 에스케이바이오랜드 주식회사
    • 김기호김영희고강일최봉락김경태이수희
    • A61K31/352A61K31/35A61P39/06
    • A topical composition comprising norbergenin having improved skin safety and storage stability in cosmetics is provided to inhibit expression of collagenase, promote synthesis of collagen, and inhibit skin wrinkles without side effects. A topical composition for inhibiting skin aging comprises 0.01-10wt.% of norbergenin isolated from Ardisia crenata, Ardisia japonica, Mallotus japonicus, Astilbe chinensis Maxim or Bergenia crassifolia, and is a pharmaceutical composition having a formulation selected from cream, gel, patch, spray, ointment, plaster, lotion, liniment, pasta or cataplasma or a cosmetic composition having a formulation selected from cosmetic lotion, skin, milk lotion, nutrition lotion, nutrition cream, massage cream, essence and pack.
    • 提供了包含具有改善的化妆品中皮肤安全性和储存稳定性的诺贝恩根素的局部组合物,以抑制胶原酶的表达,促进胶原蛋白的合成,并且抑制皮肤皱纹而没有副作用。 用于抑制皮肤老化的局部组合物包含0.01-10重量%的从赤霞珠,日本粳稻,日本梧桐,马斯客或卑尔根酵母分离的诺贝克根素,并且是具有选自霜,凝胶,贴剂,喷雾剂 ,软膏,石膏,洗剂,搽剂,面食或粘膜或具有选自化妆品乳液,皮肤,乳液,营养乳液,营养霜,按摩霜,精华和包装的制剂的化妆品组合物。