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    • 5. 发明专利
    • Nmr measurement device with temperature control element for sample vial
    • 具有温度控制元件的NMR测量装置
    • JP2014089178A
    • 2014-05-15
    • JP2013186333
    • 2013-09-09
    • Bruker Biospin Agブルーカー バイオシュピン アー・ゲー
    • PHILIPP GISLERDIRK WILHELMCHRISTOPH PFENNINGER
    • G01R33/31G01R33/32
    • G01R33/31
    • PROBLEM TO BE SOLVED: To provide an NMR measurement device with a temperature control element for a sample vial.SOLUTION: An NMR measurement device includes a temperature control element for a sample vial 1 where a temperature control fluid 8 brought under the temperature control of a heater 12 flows at its periphery. Further, the NMR measurement device is provided with a temperature sensor 9 such that a measurement head projects into a measurement space 14 spatially closely to the sample vial 1. A supply wire for the temperature sensor 9 is arranged in another space different from the measurement space 14. The temperature sensor 9 including the supply wire is surrounded with the sensor tube 15 at a radius distance, and a partial flow of the temperature control fluid 8 enters a free space 17 as a temperature control flow 16 from the measurement space 14 through a sensor flow entrance 26 and exits from the sensor tube 15 through a sensor flow exit 18 at an end on the opposite side from the sensor tube 15. Consequently, a temperature crossover and a temperature difference (ΔTp) between the temperature sensor 9 and sample vial 1 are both minimized.
    • 要解决的问题:提供具有用于样品瓶的温度控制元件的NMR测量装置。解决方案:NMR测量装置包括用于样品瓶1的温度控制元件,其中温度控制流体8在温度控制下 加热器12在其周边流动。 此外,NMR测量装置设置有温度传感器9,使得测量头在空间上突出到测量空间14中。温度传感器9的供应线布置在与测量空间不同的另一空间中 包括电源线的温度传感器9以半径距离被传感器管15包围,并且温度控制流体8的部分流动作为温度控制流16从测量空间14进入自由空间17,通过 传感器流入口26并通过传感器流出口18在传感器管15的相对侧的端部处从传感器管15离开。因此,温度传感器9和温度传感器9之间的温度差异(&Dgr; Tp) 样品瓶1都被最小化。
    • 10. 发明专利
    • Static magnetic field control method of nmr apparatus
    • NMR装置的静磁场控制方法
    • JP2012098159A
    • 2012-05-24
    • JP2010246164
    • 2010-11-02
    • Jeol Resonance Inc株式会社 Jeol Resonance
    • NISHIOGI NAOKI
    • G01R33/387G01R33/31G01R33/32G01R33/389
    • G01R33/3875G01R33/31G01R33/46G01R33/4804
    • PROBLEM TO BE SOLVED: To provide a static magnetic field control method of an NMR apparatus capable of realizing an uniform static magnetic field even when having a temperature gradient in a sample tube.SOLUTION: The static magnetic field control method of the NMR apparatus comprises: setting a temperature in the sample tube as a given temperature; obtaining resonance frequency distributions in the sample tube relative to two respective peaks present in the NMR spectrum of a sample for calibration from NMR measurement; obtaining a distribution of chemical shift differences in the sample tube relative to the two respective peaks, based on a difference between resonance frequency distributions relative to the two respective peaks; obtaining a temperature distribution in the sample tube at the preset temperature based on the distribution of the chemical shift differences relative to the two peaks; obtaining a chemical shift distribution of a solvent used for measurement in the sample tube at the preset temperature based on the temperature distribution in the sample tube at the preset temperature; and performing shim adjustment using a magnetic field gradient based on the chemical shift distribution of the solvent.
    • 要解决的问题:提供即使在样品管中具有温度梯度时也能够实现均匀静磁场的NMR装置的静态磁场控制方法。 解决方案:NMR装置的静磁场控制方法包括:将样品管中的温度设定为给定温度; 获得样品管中相对于存在于用于从NMR测量校准的样品的NMR光谱中的两个相应峰的共振频率分布; 基于相对于两个相应峰的共振频率分布之间的差异,获得样品管中相对于两个相应峰的化学位移差的分布; 基于相对于两个峰的化学位移差的分布,在预定温度下获得样品管中的温度分布; 基于样品管中的预定温度下的温度分布,在预定温度下获得用于样品管中的测量的溶剂的化学位移分布; 并且使用基于溶剂的化学位移分布的磁场梯度来执行垫片调整。 版权所有(C)2012,JPO&INPIT