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1. 发明专利

JP2010181278A Dispensing apparatus 有权
标题翻译：分配装置
公开(公告)号：JP2010181278A
公开(公告)日：2010-08-19
申请号：JP2009025111
申请日：2009-02-05
申请人： Yokogawa Electric Corp , 横河電機株式会社
发明人： KEI KOSHI , NEZU TAICHIRO
IPC分类号： G01N35/10 , B01J4/00
摘要： PROBLEM TO BE SOLVED: To provide a dispensing apparatus capable of loading a chip unfailingly and performing error-free dropping. SOLUTION: The dispensing apparatus includes a dispensing pump stored in a first transporting part, a chip loading part secured to the dispensing pump, a chip rack placed on a second transporting part and keeping a plurality of detachably inserted chips, an image capturing part photographing the surface of the chip rack, an image processing part processing captured images, and a control part controlling operations of the first transporting part and the dispensing pump on the basis of the images from the image capturing part. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供一种能够可靠地加载芯片并执行无差错下落的分配装置。解决方案：分配装置包括存储在第一输送部分中的分配泵，固定到分配泵的芯片装载部分，放置在第二传送部分上并保持多个可拆卸插入的芯片的芯片架，图像捕获部分拍摄芯片架的表面，图像处理部分处理捕获的图像，以及控制部分，其基于来自图像捕获部分的图像来控制第一输送部分和分配泵的操作。版权所有（C）2010，JPO＆INPIT

2. 发明专利

JP2009282103A Confocal scanner microscope 审中-公开
标题翻译： CONFOCAL扫描仪MICROSCOPE
公开(公告)号：JP2009282103A
公开(公告)日：2009-12-03
申请号：JP2008131689
申请日：2008-05-20
申请人： Yokogawa Electric Corp , 横河電機株式会社
发明人： TAKAI HIRONORI , KOSUGI YASUHITO , KEI KOSHI
IPC分类号： G02B21/06 , G01N21/64 , G02B6/287
摘要： PROBLEM TO BE SOLVED: To provide a compact confocal scanner microscope by eliminating the need of a dichroic mirror of a light source part , and eliminating an influence of a pointing stability, while facilitating incidence of a laser beam into an optical fiber. SOLUTION: This confocal scanner microscope includes: the light source part emitting exciting light for exciting a sample; a scanner part scanning the sample using the exciting light; and a light detecting part including an imaging camera capturing an image of the sample on receiving fluorescence emitted from the sample. The light source part includes a plurality of light sources oscillating laser beams different in wavelength and configured to input the light beams from the plurality of light sources to the scanner part through a wavelength selective optical fiber coupler. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：为了提供一种紧凑的共聚焦扫描仪显微镜，通过消除对光源部分的分色镜的需要，并且消除了指向稳定性的影响，同时促进激光束入射到光纤中。解决方案：该共焦扫描仪显微镜包括：发光激发光的光源部分，用于激发样品; 扫描仪部分使用激发光扫描样品; 以及光检测部分，其包括在接收从样品发出的荧光的情况下拍摄样品的图像的成像摄像机。光源部分包括多个振荡不同波长的激光束的光源，并被配置为通过波长选择性光纤耦合器将来自多个光源的光束输入到扫描器部分。版权所有（C）2010，JPO＆INPIT

3. 发明专利

JP2006078772A Confocal microscope 审中-公开
标题翻译： CONFOCAL MICROSCOPE
公开(公告)号：JP2006078772A
公开(公告)日：2006-03-23
申请号：JP2004262610
申请日：2004-09-09
申请人： Yokogawa Electric Corp , 横河電機株式会社
发明人： MIKURIYA KENTA , KEI KOSHI , YOSHIDA TAKASHI
IPC分类号： G02B21/00
CPC分类号： G02B21/0076 , G02B21/0044 , G02B21/0064
摘要： PROBLEM TO BE SOLVED: To realize a confocal microscope capable of observing reactions of luminous stimulus and fluorescence discoloration in real time by high-speed image measurement peculiar to a Nipkow disk system by adding a function for performing the luminous stimulus to a Nipkow disk system confocal microscope.
SOLUTION: The confocal microscope is constituted of at least a microscope and a Nipkow disk system confocal scanner so as to perform the observation of a sample by a confocal image, and has a laser beam output means connected to the microscope and outputting a laser beam to stimulate the sample.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：为了实现能够通过对Nipkow盘系统特有的高速图像测量实时观察发光刺激和荧光变色的反应的共焦显微镜，通过向Nipkow添加执行发光刺激的功能磁盘系统共聚焦显微镜。解决方案：共焦显微镜由至少一台显微镜和一个Nipkow盘系统共聚焦扫描器构成，以便通过共聚焦图像进行样品的观察，并具有连接到显微镜的激光束输出装置，并输出激光束刺激样品。版权所有（C）2006，JPO＆NCIPI

4. 发明专利

JP2006058321A Three-dimensional confocal microscopic system 有权
标题翻译：三维协同微观系统
公开(公告)号：JP2006058321A
公开(公告)日：2006-03-02
申请号：JP2004236899
申请日：2004-08-17
申请人： Yokogawa Electric Corp , 横河電機株式会社
发明人： KEI KOSHI
IPC分类号： G02B21/36 , G01N21/64
摘要： PROBLEM TO BE SOLVED: To realize a three-dimensional confocal microscopic system designed such that images used for micro PIV are acquired at the same focusing position by using accurate position information from an actuator.
SOLUTION: The three-dimensional confocal microscopic system includes: a confocal scanner for acquiring the slice images of a micro conduit as confocal images via a microscope; a video camera for outputting the image data of the confocal images; an actuator for moving the focusing position of the objective lens of the microscope in the direction of its optical axis; a control section for generating a scanning waveform signal for scanning the objective lens in the direction of the optical axis via the actuator; and an image processing section for calculating the speed of a fluid in the micro conduit on the basis of at least the two image data acquired by the video camera. Based upon a position signal output from the actuator, the system acquires at least the two images in a prescribed position in the micro conduit.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：实现三维共焦显微系统，其被设计为使得通过使用来自致动器的精确位置信息在相同聚焦位置处获取用于微型PIV的图像。解决方案：三维共焦显微系统包括：共焦扫描器，用于通过显微镜获取微管道的切片图像作为共焦图像; 用于输出共焦图像的图像数据的摄像机; 用于使显微镜的物镜的聚焦位置沿其光轴方向移动的致动器; 控制部分，用于产生用于经由致动器沿光轴的方向扫描物镜的扫描波形信号; 以及图像处理部，其基于至少由摄像机获取的两个图像数据计算微导管中的流体的速度。基于从致动器输出的位置信号，系统至少在微管道中的规定位置获取两个图像。版权所有（C）2006，JPO＆NCIPI

5. 发明专利

JP2005234030A Confocal microscope 审中-公开
标题翻译： CONFOCAL MICROSCOPE
公开(公告)号：JP2005234030A
公开(公告)日：2005-09-02
申请号：JP2004040008
申请日：2004-02-17
申请人： Yokogawa Electric Corp , 横河電機株式会社
发明人： KEI KOSHI , MIKURIYA KENTA , HIRUKAWA HIDEO
IPC分类号： G01N21/64 , G02B21/00
摘要： PROBLEM TO BE SOLVED: To provide a confocal microscope which is capable of observing a sample with multicolors by using a Nipkow disk system confocal scanner and a spectroscopic unit and does not require image processing with respect to an inversion image because a transmission image and a reflection image of dichroic mirror can be corrected in the same direction in the spectroscopic optical unit.
SOLUTION: The confocal microscope has the spectroscopic unit which spectroscopes an optical image outputted from the Nipkow disk system confocal scanner and performs multicolor observation of the sample, wherein the spectroscopic unit is provided with a plurality of spectroscopic means having the different reflection and transmission characteristics according to the spectroscopy for the optical image and an inversion means that inverts the optical image reflected by the spectroscopic means.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供一种共焦显微镜，其能够使用Nipkow盘系统共聚焦扫描器和分光单元观察具有多色光标的样品，并且不需要相对于反转图像的图像处理，因为透射图像并且可以在分光光学单元中沿相同的方向校正分色镜的反射图像。共聚焦显微镜具有对从Nipkow磁盘系统共聚焦扫描仪输出的光学图像进行分光的分光单元，对样品进行多色观察，其中，分光单元具有多个具有不同反射的分光装置，根据光学图像的光谱学的透射特性以及反转由该光谱装置反射的光学图像的反转装置。版权所有（C）2005，JPO＆NCIPI

6. 发明专利

JP2004317704A Three-dimensional confocal microscope 审中-公开
标题翻译：三维共焦显微镜
公开(公告)号：JP2004317704A
公开(公告)日：2004-11-11
申请号：JP2003109934
申请日：2003-04-15
申请人： Yokogawa Electric Corp , 横河電機株式会社
发明人： AKIYAMA TAKASHI , KEI KOSHI , MIKURIYA KENTA
IPC分类号： G02B21/00 , G02B3/14 , G02B21/36
CPC分类号： G02B26/005
摘要： PROBLEM TO BE SOLVED: To provide a three-dimensional confocal microscope capable of preventing mechanical vibration from occurring in a scanning means in an optical axis direction and also performing scanning in the optical axis direction at high speed.
SOLUTION: In the confocal microscope constituted by attaching a confocal scanner to an optical microscope so that the image of a sample can be acquired as a confocal image by the confocal scanner, a surface tension control type variable focus lens having no movable part is used as the field lens of the microscope.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供能够防止在光轴方向上的扫描装置中发生机械振动并且还以高速在光轴方向上进行扫描的三维共聚焦显微镜。解决方案：在通过将共聚焦扫描仪附着到光学显微镜而构成的共聚焦显微镜中，使得可以通过共聚焦扫描器获取样品的图像作为共焦图像，表面张力控制型可变焦距透镜不具有可移动部分用作显微镜的镜头。版权所有（C）2005，JPO＆NCIPI

7. 发明专利

JP2013024906A Laser microscope 有权
标题翻译：激光显微镜
公开(公告)号：JP2013024906A
公开(公告)日：2013-02-04
申请号：JP2011156539
申请日：2011-07-15
申请人： Yokogawa Electric Corp , 横河電機株式会社
发明人： KEI KOSHI
IPC分类号： G02B21/06 , G01N21/64
摘要： PROBLEM TO BE SOLVED: To provide a laser microscope guaranteeing brightness in an acquired confocal image and improving reliability of image analysis.SOLUTION: A laser microscope includes: a flat plate turret arranged in a direction perpendicular to an optical axis of a laser beam emitted from a laser light source; a plurality of objective lenses arranged on a circumference of the turret for entering the laser beam emitted from the laser light source thereto; a sample arranged to face one of the objective lenses. The laser microscope is configured to irradiate the laser beam emitted from the laser light source on the sample through a dichroic mirror and the objective lenses, to condense fluorescent signals emitted from the irradiated sample, and to obtain a fluorescent image on an imaging plane of the imaging lens. The laser microscope is provided with a control means for controlling output of the laser beam emitted from the laser light source to be constant based on output of an optical sensor by arranging the optical sensor on the circumference of the turret on which the objective lenses are arranged.
摘要翻译：要解决的问题：提供确保获得的共聚焦图像中的亮度的激光显微镜，并提高图像分析的可靠性。解决方案：激光显微镜包括：平板转台，其布置在垂直于从激光光源发射的激光束的光轴的方向上; 多个物镜，布置在转台的圆周上，用于将从激光光源发射的激光束进入其中; 布置成面对一个物镜的样品。激光显微镜被配置为通过分色镜和物镜将从激光光源发射的激光束照射在样品上，以冷凝从被照射的样品发射的荧光信号，并且在成像平面上获得荧光图像成像镜头。激光显微镜具备控制装置，用于通过将光学传感器配置在其上配置有物镜的转台的圆周上，基于光学传感器的输出来控制从激光源发射的激光束的输出为恒定的控制装置。版权所有（C）2013，JPO＆INPIT

8. 发明专利

JP2012181243A Confocal scanner 审中-公开
标题翻译：协同扫描仪
公开(公告)号：JP2012181243A
公开(公告)日：2012-09-20
申请号：JP2011042412
申请日：2011-02-28
申请人： Yokogawa Electric Corp , 横河電機株式会社
发明人： KEI KOSHI
IPC分类号： G02B21/00 , G02B3/00
CPC分类号： G02B21/0044
摘要： PROBLEM TO BE SOLVED: To provide a confocal scanner with improved aberration for incidence of a plurality of light beams with different wavelengths.SOLUTION: A light-condensing disk used for a confocal scanner comprises a doublet-type microlens configured to make focuses of multiple wavelengths coincide.
摘要翻译：要解决的问题：为了提供具有不同波长的多个光束入射的改进的像差的共焦扫描器。解决方案：用于共聚焦扫描器的聚光盘包括配置成使多个波长的聚焦重合的双峰型微透镜。版权所有（C）2012，JPO＆INPIT

9. 发明专利

JP2010210237A Drug discovery screening apparatus 有权
标题翻译：药物发现筛选装置
公开(公告)号：JP2010210237A
公开(公告)日：2010-09-24
申请号：JP2009050065
申请日：2009-03-04
申请人： Yokogawa Electric Corp , 横河電機株式会社
发明人： KEI KOSHI , NEZU TAICHIRO , YAMAMOTO KOICHI , SUZUKI TOSHIYUKI
IPC分类号： G01N35/04 , G01N21/17 , G01N35/00 , G01N35/10
CPC分类号： G01N35/02 , G01N35/0099 , G01N35/028 , G01N2035/042 , G01N2035/0462 , G01N2035/0465 , Y10T436/113332 , Y10T436/114165
摘要： PROBLEM TO BE SOLVED: To provide a screening apparatus capable of improving a testing operation efficiency. SOLUTION: The apparatus includes an incubator unit integrally connected to an image measurement unit, a fixed stage disposed at the incubator unit, a first conveyance means for taking out one of plates stored in a carousel of the incubator unit on the fixed stage, a second conveyance means for conveying the plate taken out onto the fixed stage onto an XY stage disposed at the image measurement unit, and a control unit for controlling operation of the image measurement unit and the incubator. The second conveyance means is structured of the first conveyance arms and the second conveyance arms, respectively supported horizontally by a conveyance unit support section, and the first and second conveyance arms are constituted so as to convey the plates on the fixed stage and the plates on the XY stage in the crossed state each other. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供一种能够提高测试操作效率的筛选装置。解决方案：该装置包括与图像测量单元一体地连接的培养箱单元，设置在培养箱单元的固定台，用于取出存储在固定台上的培养箱单元的转盘中的一个板的第一输送装置用于将取出到固定台上的板传送到设置在图像测量单元上的XY台上的第二传送装置，以及用于控制图像测量单元和培养箱的操作的控制单元。第二输送装置由分别由输送单元支撑部水平地支撑的第一输送臂和第二输送臂构成，第一输送臂和第二输送臂构成为将固定台上的板和板上的板 XY阶段处于交叉状态。版权所有（C）2010，JPO＆INPIT

10. 发明专利

JP2009210889A Confocal microscope system 审中-公开
标题翻译： CONFOCAL MICROSCOPE系统
公开(公告)号：JP2009210889A
公开(公告)日：2009-09-17
申请号：JP2008054887
申请日：2008-03-05
申请人： Yokogawa Electric Corp , 横河電機株式会社
发明人： SUZUKI TOSHIYUKI , KEI KOSHI
IPC分类号： G02B21/06 , G01N21/64
CPC分类号： G02B21/0044
摘要： PROBLEM TO BE SOLVED: To provide a confocal microscope system that can have confocal properties regardless of the magnification of objective lenses. SOLUTION: The confocal microscope system is configured in such a way that a specimen is irradiated with excitation light for exciting the specimen via a confocal scanner and microscope, and a fluorescent image formed by the excitation of the specimen is input to a camera via the microscope and confocal scanner. In the confocal microscope system, the microscope has the plurality of objective lenses of different magnifications. the confocal scanner has: a Nipkow disk in which a plurality of lines of pin holes of different diameters are formed; a microlens array disk disposed opposite the Nipkow disk and having a plurality of microlenses for condensing the fluorescent image formed by the excitation, to the pin holes; and a plurality of dichroic mirrors of different thicknesses disposed between the Nipkow disk and the microlens array disk. When objective lenses with high (low) magnification are selected, the thick (thin) dichroic mirrors are disposed on the optical axis of the excitation light, thereby making the fluorescent image incident on the pin holes of large (small) diameters. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供可以具有共焦特性的共聚焦显微镜系统，而不管物镜的放大倍数。解决方案：共焦显微镜系统被配置成使得通过共聚焦扫描器和显微镜照射用于激发样品的激发光的样品，并且通过将样品的激发形成的荧光图像输入到照相机通过显微镜和共焦扫描仪。在共聚焦显微镜系统中，显微镜具有不同放大率的多个物镜。共焦扫描器具有：形成不同直径的多个销孔的线的Nipkow盘; 一个微透镜阵列盘，与微孔盘相对设置，并具有多个微透镜，用于将由激发形成的荧光图像聚焦到针孔; 以及设置在Nipkow盘和微透镜阵列盘之间的多个不同厚度的分色镜。当选择具有高（低）倍率的物镜时，厚（薄）分色镜设置在激发光的光轴上，从而使荧光图像入射到大（小）直径的针孔上。版权所有（C）2009，JPO＆INPIT

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