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1. 发明专利

JP2007268183A Iontophoresis apparatus 审中-公开
标题翻译： IOPOPHORESIS设备
公开(公告)号：JP2007268183A
公开(公告)日：2007-10-18
申请号：JP2006100752
申请日：2006-03-31
申请人： Transcutaneous Technologies Inc , トランスキュー・テクノロジーズ株式会社
发明人： MATSUMURA TAKEHIKO , NAKAYAMA HATOO , SHIBATA TSUTOMU , SERIZAWA KOJI
IPC分类号： A61N1/30
摘要： PROBLEM TO BE SOLVED: To make it possible to prevent the corrosion of the power source 60 by a vaporized medical liquid due to the vaporization from the part where the medical liquid is held. SOLUTION: The iontophoresis apparatus 10 has an apparatus body 50 percutaneously administering an ionized medical drug by iontophoresis, a power source 60 supplying electricity to the apparatus body 50, and the flexible connector 70 extending from the apparatus body 50 and electrically connected to the apparatus body 50 and the power source 60, the power source 60 is arranged on the face opposite to the face contacting with the skin in the apparatus body 50 with the connector 70 curved. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：为了能够防止由于来自保持医用液体的部分的气化而导致的蒸发的医用液体的电源60的腐蚀。离子电渗疗法装置10具有通过离子电渗法经皮给药离子化药物的装置体50，向装置主体50供电的动力源60以及从装置主体50延伸出的电连接到设备主体50和电源60，电源60设置在与连接器70弯曲的装置主体50中与皮肤接触的面相反的表面上。版权所有（C）2008，JPO＆INPIT

2. 发明专利

JP2007097689A Iontophoresis apparatus and photodynamic therapy system using iontophoresis apparatus 审中-公开
标题翻译： IOPOPHORESIS设备和使用IOPOPHORESIS设备的光电治疗系统
公开(公告)号：JP2007097689A
公开(公告)日：2007-04-19
申请号：JP2005288811
申请日：2005-09-30
申请人： Transcutaneous Technologies Inc , トランスキュー・テクノロジーズ株式会社
发明人： KAWAKAMI HIROYOSHI , SHIBATA TSUTOMU , AKIYAMA HIDEO , NAKAYAMA HATOO , MATSUMURA TAKEHIKO , MATSUMURA AKIHIKO
IPC分类号： A61N1/30 , A61K31/409 , A61P35/00
摘要： PROBLEM TO BE SOLVED: To provide an iontophoresis apparatus which can administer photosensitive matter to only a malignant tumor cell. SOLUTION: The iontophoresis apparatus is equipped with an electrode 22A connected to a power source 12, an electrolyte holding section 26A which is arranged in the front of the electrode 22A and holds an electrolyte, an anion exchange membrane 28A which is arranged in the front of the electrolyte holding section 26A and passes an anion selectively, a liquid medicine holding section 30A which is arranged in the front of the anion exchange membrane 28A and holds a photosensitization reactant, a cation exchange membrane 32A which is arranged in the front of the liquid medicine holding section 30A and passes a cation selectively, a working side electrode structure 20A which is arranged in a part on the front side of the cation exchange membrane 32A and has at least a release-inhibiting layer 40 to control the release of the photosensitization reactant, and a position index which is formed in the working side electrode structure 20A and can specify the position of a pasting face 60A to a living body. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供一种可以将光敏物质仅施用于恶性肿瘤细胞的离子电渗疗法。解决方案：离子电渗仪装置配备有连接到电源12的电极22A，布置在电极22A的前面并保持电解质的电解质保持部26A，阴离子交换膜28A 电解质保持部26A的前方，通过阴离子选择性地配置在阴离子交换膜28A的前方并保持有光敏性反应物的液体药剂保持部30A，配置在阴离子交换膜28A的前方的阳离子交换膜32A 液体药剂保持部30A选择性地通过阳离子，设置在阳离子交换膜32A的前侧的一部分中的工作侧电极结构20A，并具有至少一个释放抑制层40，以控制阳离子交换膜32A的释放。光敏反应物和在工作侧电极结构20A中形成的位置指数，并且可以将粘贴面60A的位置指定为活体。版权所有（C）2007，JPO＆INPIT

3. 发明专利

JP2007089821A Iontophoresis apparatus 审中-公开
标题翻译： IOPOPHORESIS设备
公开(公告)号：JP2007089821A
公开(公告)日：2007-04-12
申请号：JP2005283112
申请日：2005-09-28
申请人： Transcutaneous Technologies Inc , トランスキュー・テクノロジーズ株式会社
发明人： MATSUMURA TAKEHIKO , KANEMURA KIYOSHI , NAKAYAMA HATOO , AKIYAMA HIDEO , MATSUMURA AKIHIKO
IPC分类号： A61N1/30 , A61N1/04
摘要： PROBLEM TO BE SOLVED: To provide an iontophoresis apparatus capable of receiving a procedural advantage for granting an approval and a registration on the safety and the efficacy executed by government organizations. SOLUTION: This iontophoresis apparatus is provided with a first conductivity type ion exchange membrane doped with first conductivity type medicine ions, and a voltage impressing member for impressing a voltage to the first ion exchange membrane; and the voltage impressing member includes an electrode, an electrolyte retaining section retaining electrolyte coming into contact with the electrode and a detachable impermeable separator disposed in the front face side of the electrolyte retaining section. This iontophoresis apparatus is constituted to dose the medicine ions in such a state that the separator is detached and the first ion exchange membrane is disposed in the front face side of the electrolyte retaining section. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供一种离子电渗仪器，能够获得批准和注册政府机构执行的安全性和效力的程序优势。解决方案：该离子电渗仪设置有掺杂有第一导电型药物离子的第一导电型离子交换膜和用于向第一离子交换膜施加电压的电压施加构件; 并且电压施加构件包括电极，与电极接触的保持电解质的电解质保留部分和设置在电解质保持部的正面侧的可拆卸的不可渗透隔板。该离子电渗疗法装置构成为以分离器分离的状态剂量药物离子，第一离子交换膜设置在电解质保持部的正面侧。版权所有（C）2007，JPO＆INPIT

4. 发明专利

JP2007089776A Low-frequency treating device 审中-公开
标题翻译：低频处理装置
公开(公告)号：JP2007089776A
公开(公告)日：2007-04-12
申请号：JP2005282222
申请日：2005-09-28
申请人： Transcutaneous Technologies Inc , トランスキュー・テクノロジーズ株式会社
发明人： AKIYAMA HIDEO , NAKAYAMA HATOO , MATSUMURA TAKEHIKO , MATSUMURA AKIHIKO
IPC分类号： A61N1/36 , A61N1/04 , A61N1/30
摘要： PROBLEM TO BE SOLVED: To promote treating effect in a low-frequency treating device having a different electrode and an indifferent electrode. SOLUTION: The low-frequency treating device 10 has a different electrode pad 12, an indifferent electrode pad, and a low-frequency power source 16 connected to the different electrode pad 12 and the indifferent electrode pad, and further is equipped with an iontophoresis device 18 capable of being installed in the different electrode pad 12. The iontophoresis device 18 is constituted including: an action side electrode structure for administering a drug ion by iontophoresis; a non-action side electrode structure which becomes a counter electrode when administering the drug ion from the action side electrode structure; and a DC power source connected to the action side electrode structure and the non-action side electrode structure in different polarities. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：解决的问题：为了促进具有不同电极和无电极的低频处理装置的处理效果。解决方案：低频处理装置10具有不同的电极焊盘12，无关电极焊盘和连接到不同电极焊盘12和无电极焊盘的低频电源16，并且还配备有离子电渗疗装置18，其特征在于，具有：离子电渗疗法给予药物离子的动作侧电极结构体，非作用侧电极结构，当从动作侧电极结构施用药物离子时成为对电极; 以及以不同极性连接到动作侧电极结构和非动作侧电极结构的DC电源。版权所有（C）2007，JPO＆INPIT

5. 发明专利

JP2007089664A Iontophoresis apparatus 审中-公开
标题翻译： IOPOPHORESIS设备
公开(公告)号：JP2007089664A
公开(公告)日：2007-04-12
申请号：JP2005280336
申请日：2005-09-27
申请人： Transcutaneous Technologies Inc , トランスキュー・テクノロジーズ株式会社
发明人： NAKAYAMA HATOO , TSUJI KAZUYUKI , MATSUMURA TAKEHIKO , AKIYAMA HIDEO , MATSUMURA AKIHIKO
IPC分类号： A61N1/30
摘要： PROBLEM TO BE SOLVED: To provide an iontophoresis apparatus which can be carried and can be used as a single unit. SOLUTION: This iontophoresis apparatus is equipped with a main body section 100 and a power source section 200 which is a separate body from the main body section 100. In this case, the main body section has a first electrode member 152, a second electrode member 154, a chemical holding section 124, and a pair of inputting electrodes 132 and 134 to which a voltage is fed. The first electrode member 152 is charged with a voltage having the same polarity as an ionized medicine. The second electrode member 154 is charged with a voltage having a different polarity from the first electrode member 152. The chemical holding section 124 holds the medicine in an electric field between the first electrode member 152 and the second electrode member 154. The power source section 200 has a power source and outputting electrodes 242 and 244 for feeding the output of the power source to the outside, and forms an electric potential difference between the inputting electrodes 132 and 134 through the outputting electrodes 242 and 244 when being fitted on the main body section 100. In an initial stage, the main body section 100 and the power source section 200 are packaged in a manner to be electrically and chemically isolated from each other. When the packaging is unpacked, and the power source section 200 is fitted on the main body section 100, the iontophoresis device becomes operable. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供可携带并可用作单个单元的离子电渗疗法装置。解决方案：该离子电渗疗法装置具有主体部分100和与主体部分100分开的主体部分200。在这种情况下，主体部分具有第一电极部件152，第二电极部件154，化学保持部124以及供给电压的一对输入电极132,134。第一电极构件152以与离子化药物相同极性的电压进行充电。第二电极部件154以与第一电极部件152的极性不同的电压进行充电。化学保持部124将药物保持在第一电极部件152和第二电极部件154之间的电场中。电源部 200具有电源，并且输出用于将电源的输出馈送到外部的电极242和244，并且当安装在主体上时通过输出电极242和244在输入电极132和134之间形成电位差在初始阶段，主体部分100和电源部分200以彼此电气和化学隔离的方式被封装。当包装被包装并且电源部分200装配在主体部分100上时，离子电渗疗装置变得可操作。版权所有（C）2007，JPO＆INPIT

6. 发明专利

JP2007075501A Absorption accelerating type iontophoresis device 审中-公开
标题翻译：吸收式加速型异构体装置
公开(公告)号：JP2007075501A
公开(公告)日：2007-03-29
申请号：JP2005270337
申请日：2005-09-16
申请人： Transcutaneous Technologies Inc , トランスキュー・テクノロジーズ株式会社
发明人： AKIYAMA HIDEO , NAKAYAMA HATOO , MATSUMURA TAKEHIKO , MATSUMURA AKIHIKO
IPC分类号： A61N1/30
摘要： PROBLEM TO BE SOLVED: To provide an iontophoresis device, giving a dose of drug to the interior of a living body at a high permeable quantity. SOLUTION: This iontophoresis device includes: a power supply device; a first electrode structure connected to the power supply device to emit an ionic drug by iontophoresis and perform percutaneous administration to the living body; and a second electrode structure as a counter electrode for the first electrode structure, wherein the first electrode structure holds an absorption accelerator and the absorption accelerator and ionic drug are given from the first electrode structure to the living body. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供一种离子电渗疗法装置，以高渗透量给予活体内部的药物剂量。该离子电渗装置包括：电源装置; 连接到电源装置的第一电极结构，通过离子电渗法发射离子药物，并对生物进行经皮给药; 以及作为第一电极结构的对电极的第二电极结构，其中，所述第一电极结构保持吸收促进剂，并且所述吸收促进剂和离子药物从所述第一电极结构体向所述活体赋予。版权所有（C）2007，JPO＆INPIT

7. 发明专利

JP2007061277A Assembly kit for iontophoresis equipment 审中-公开
标题翻译：装配设备的装配工具
公开(公告)号：JP2007061277A
公开(公告)日：2007-03-15
申请号：JP2005249399
申请日：2005-08-30
申请人： Transcutaneous Technologies Inc , トランスキュー・テクノロジーズ株式会社
发明人： TSUJI KAZUYUKI , NAKAYAMA HATOO , MATSUMURA TAKEHIKO , AKIYAMA HIDEO , MATSUMURA AKIHIKO
IPC分类号： A61N1/30
摘要： PROBLEM TO BE SOLVED: To provide an assembly kit for assembling an electrode structure speedily and simply in the case of using iontophoresis equipment.
SOLUTION: The assembly kit for the iontophoresis equipment comprises: a disk-like support member 22 having a prescribed thickness; a functional layer 23 which is arranged so as to fit detachably into a recess part or a blanked part formed at the support member 22 and composed of one or more layers constituting the iontophoresis equipment; and a cover film 24 provided separably so as to cover, hermetically seal and protect the exposed surface of the functional layer 23.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供一种用于在使用离子电渗疗法设备的情况下快速且简单地组装电极结构的组装工具。解决方案：用于离子电渗疗法装置的装配工具包括：具有规定厚度的盘状支撑构件22; 功能层23被布置成可拆卸地装配到形成在支撑构件22上的由构成离子电渗疗法设备的一个或多个层构成的凹部或冲切部中; 以及可分离地设置以覆盖，密封并保护功能层23的暴露表面的覆盖膜24.版权所有（C）2007，JPO＆INPIT

8. 发明专利

JP2007050136A Iontophoresis apparatus 审中-公开
标题翻译： IOPOPHORESIS设备
公开(公告)号：JP2007050136A
公开(公告)日：2007-03-01
申请号：JP2005238026
申请日：2005-08-18
申请人： Transcutaneous Technologies Inc , トランスキュー・テクノロジーズ株式会社
发明人： NAKAYAMA HATOO , KANEMURA KIYOSHI , MATSUMURA TAKEHIKO , AKIYAMA HIDEO , MATSUMURA AKIHIKO
IPC分类号： A61N1/30
CPC分类号： A61N1/0444 , A61N1/0448
摘要： PROBLEM TO BE SOLVED: To simplify manufacture processes, to automate manufacture, to perform mass production or to reduce a manufacture cost in an iontophoresis apparatus of a type that first conductivity type medicament ions are doped to a first conductivity type ion exchange membrane arranged on a biological interface or an iontophoresis apparatus of a type that two ion exchange membranes of an opposite conductivity type are interposed between an electrolyte holding part and a medicament liquid holding part including the first conductivity type medicament ions. SOLUTION: At least one electrode structure of the iontophoresis apparatus is constituted so as to be provided with a composite ion exchange membrane composed of the laminated body of the first ion exchange membrane of the first conductivity type / the second ion exchange membrane of the second conductivity type or the laminated body of the first ion exchange membrane of the first conductivity type / a semi-permeable membrane / the second ion exchange membrane of the second conductivity type, for which the respective membranes are integrally joined. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：为了简化制造工艺，自动化制造，进行批量生产或降低离子电渗疗法装置中的制造成本，其中第一导电型药物离子被掺杂到第一导电型离子交换膜布置在生物界面或离子电渗疗法装置上，其类型是将两个相反导电类型的离子交换膜置于电解质保持部分和包含第一导电型药物离子的药物液体保持部分之间。解决方案：离子电渗装置的至少一个电极结构构成为具有由第一导电型/第二离子交换膜的第一离子交换膜的层叠体构成的复合离子交换膜第一导电型/第二导电类型的半透膜/第二离子交换膜的第一离子交换膜的第二导电类型或层叠体，各个膜整体接合。版权所有（C）2007，JPO＆INPIT

9. 发明专利

JP2007044258A Percutaneous absorption patch with a syringe needle insertion hole 审中-公开
标题翻译： PERCUTANEOUS吸收管配有针刺针插入孔
公开(公告)号：JP2007044258A
公开(公告)日：2007-02-22
申请号：JP2005231824
申请日：2005-08-10
申请人： Transcutaneous Technologies Inc , トランスキュー・テクノロジーズ株式会社
发明人： NAKAYAMA HATOO , MATSUMURA TAKEHIKO , AKIYAMA HIDEO , MATSUMURA AKIHIKO
IPC分类号： A61M37/00 , A61K9/70 , A61N1/30
摘要： PROBLEM TO BE SOLVED: To make it possible to inject a substance having synergistic effects with a percutaneously absorbed drug on the site fitted with a percutaneous absorption patch without peeling off the patch. SOLUTION: The percutaneous absorption patch is designed to introduce a drug into a living body by percutaneous absorption with one side of the surface attached on the living body and comprises a syringe needle insertion hole 12 for penetrating through from one side of the surface to the other side. COPYRIGHT: (C)2007,JPO&INPIT

10. 发明专利

JP2007037640A Iontophoresis apparatus 审中-公开
标题翻译： IOPOPHORESIS设备
公开(公告)号：JP2007037640A
公开(公告)日：2007-02-15
申请号：JP2005222893
申请日：2005-08-01
申请人： Transcutaneous Technologies Inc , トランスキュー・テクノロジーズ株式会社
发明人： MATSUMURA TAKEHIKO , KANEMURA KIYOSHI , NAKAYAMA HATOO , AKIYAMA HIDEO , MATSUMURA AKIHIKO
IPC分类号： A61N1/30
CPC分类号： A61N1/0448 , A61N1/0436 , A61N1/0444
摘要： PROBLEM TO BE SOLVED: To provide an iontophoresis apparatus which can keep a medical solution for a long period of time without discoloring the medical solution, depositing crystals in a medical solution retaining part, reducing medicinal effects, and generating harmful substances due to the alteration of the medical substance.
SOLUTION: In the iontophoresis apparatus equipped with an electrolyte retaining part for retaining an electrolytic solution dissociated into first electrolytic ions of a first conductive type and second electrolytic ions of a second conductive type in a solution and the medical solution retaining part which is disposed in front of the electrolyte retaining part and keeps a solution of the medical substance dissociated into medical ions, or ions produced by ionic dissociation of the medical substance, of the first conductive type and medical counter ions, or the counter ions of the medical ions, of the second conductive type in the solution, a first ion-exchange membrane where an ion-exchange group of the first conductive type is introduced and a second ion-exchange membrane where an ion-exchange group of the second conductive type is introduced are disposed between the electrolyte retaining part and the medical solution retaining part.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供一种离子电渗疗法，其可以长时间保持药液而不会使医用溶液变色，将晶体沉积在药液保留部分中，减少药物作用，并由于产生有害物质而产生有害物质药物的改变。解决方案：在配备有用于保持电解液的电解质保留部分的离子电渗疗法装置中，所述电解质保留部分用于保持溶解在第一导电类型的第一电解离子中的电解溶液和溶液中的第二导电类型的第二电解离子，设置在电解质保持部件的前面，并且使医疗物质的溶液离解成医疗离子，或由药物的离子离解产生的离子，第一导电类型和医用抗衡离子或医用离子的抗衡离子所述溶液中的第二导电类型的第一导电类型的离子交换基团被引入第一离子交换膜和引入第二导电类型的离子交换基团的第二离子交换膜是第一导电类型的第一离子交换膜，设置在电解质保持部和药液保持部之间。版权所有（C）2007，JPO＆INPIT

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