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1. 发明专利

JP2015057081A 潤滑コート剤および当該潤滑コート剤で被覆されてなる医療デバイス审中-公开
标题翻译：润滑涂层材料和涂有润滑涂料的医疗装置
公开(公告)号：JP2015057081A
公开(公告)日：2015-03-26
申请号：JP2012005564
申请日：2012-01-13
申请人：テルモ株式会社 , Terumo Corp
发明人： OMATA RIKIYA , SHINODA SAYAKA
IPC分类号： A61L29/00 , A61L31/00
CPC分类号： A61L29/085 , A61L29/14 , A61L2400/10 , C08L71/02
摘要：【課題】十分な潤滑維持性を有する潤滑性被膜を形成できる潤滑コート剤を提供する。【解決手段】繰り返し単位を有する分子量が100以上の親水性側鎖を有する親水性単量体由来の構成単位を有する親水性ドメインと、エポキシ基を有する単量体由来の構成単位を有する反応性ドメインと、を有するブロックコポリマーを含有する、潤滑コート剤。【選択図】なし
摘要翻译：要解决的问题：提供一种具有足够润滑可持续性的润滑剂涂膜的润滑剂涂料。溶剂：润滑剂涂料含有嵌段共聚物，其包括：具有衍生自具有亲水侧的亲水性单体的结构单元的亲水结构单元具有重复单元的分子量为100以上的链; 和具有衍生自具有环氧基的单体的结构单元的反应性域。

2. 发明专利

JP2013146504A Medical implement and method for producing the same 有权
标题翻译：医疗实施方法及其生产方法
公开(公告)号：JP2013146504A
公开(公告)日：2013-08-01
申请号：JP2012011532
申请日：2012-01-23
申请人： Terumo Corp , テルモ株式会社
发明人： SHINODA SAYAKA , SAWADA KENJI , OMATA RIKIYA
IPC分类号： A61L27/00 , A61M25/00 , A61M25/06 , A61M25/09
摘要： PROBLEM TO BE SOLVED: To provide a medical implement wherein a surface lubricant layer has an uneven structure to exert excellent water holding properties, and to provide a method for producing the same.SOLUTION: This medical implement includes: a base material layer; and a surface lubricant layer consisting of a hydrophilic polymer having reactive monomers covering at least a part of the base material layer. The surface lubricant layer is formed with a plurality of recessed parts, the number of the recessed parts per unit area is 1-1×10/mm, the average hole diameter of the recessed part is 1-500 μm, and the average depth Rc of the recessed part is 0.3-5 μm.
摘要翻译：要解决的问题：提供一种表面润滑剂层具有不均匀结构以发挥优异的保水性的医疗用具，并提供其制造方法。解决方案：该医疗器具包括：基材层; 以及由具有覆盖基材层的至少一部分的反应性单体的亲水性聚合物构成的表面润滑剂层。表面润滑剂层形成有多个凹部，每单位面积的凹部的数量为1-1×10 / mm，凹部的平均孔径为1-500μm，平均深度Rc 的凹部为0.3-5μm。

3. 发明专利

JP2012161372A Medical instrument and method for manufacturing the same 审中-公开
标题翻译：医用仪器及其制造方法
公开(公告)号：JP2012161372A
公开(公告)日：2012-08-30
申请号：JP2011021928
申请日：2011-02-03
申请人： Terumo Corp , テルモ株式会社
发明人： ANZAI TAKAKIMI , SHINODA SAYAKA
IPC分类号： A61L29/00 , A61L31/00 , A61M25/00 , A61M25/09
摘要： PROBLEM TO BE SOLVED: To provide a medical instrument in which a hydrophilic polymer is strongly fixed on the surface of a substrate comprising a polyamide.SOLUTION: The medical instrument includes: a substrate at least a part of the surface of which is the polyamide; an adhesive layer formed on the surface of the substrate and including a polyamide soluble in an organic solvent; and a crosslinked, surface lubricated layer formed on the upper part of the adhesive layer, and including the hydrophilic polymer having at least one reactive functional group selected from the group consisting of an epoxy group, acid chloride group, and isocyanate group, and the method for manufacturing it is provided.
摘要翻译：要解决的问题：提供一种其中亲水性聚合物牢固地固定在包含聚酰胺的基材的表面上的医疗器械。解决方案：医疗器械包括：其表面的至少一部分是聚酰胺的基底; 形成在所述基材的表面上并且包含可溶于有机溶剂的聚酰胺的粘合剂层; 以及形成在粘合剂层的上部的交联的表面润滑层，并且包括具有至少一个选自环氧基，酰氯基和异氰酸酯基的反应性官能团的亲水性聚合物，并且该方法为制造提供。版权所有（C）2012，JPO＆INPIT

4. 发明专利

JP2012000240A Medical tool having surface lubricity in wetting 审中-公开
标题翻译：具有表面润湿性的医用工具
公开(公告)号：JP2012000240A
公开(公告)日：2012-01-05
申请号：JP2010137344
申请日：2010-06-16
申请人： Terumo Corp , テルモ株式会社
发明人： OMATA RIKIYA , SAWADA KENJI , SHINODA SAYAKA , ANZAI TAKAKIMI
IPC分类号： A61L29/00 , A61L31/00
摘要： PROBLEM TO BE SOLVED: To provide a medical tool for permanently exhibiting excellent surface lubricity during use by firmly immobilizing various polymeric base materials and a surface lubricating layer with a simple method.SOLUTION: The medical tool includes: a base material layer comprising a polymeric material at least on the surface; compounds each of which is carried by at least a part of the base material layer and has a plurality of thiol groups in a molecule; and surface lubricating layers each of which covers the compound having the plurality of thiol groups in the molecule and comprises hydrophilic polymers with a reactive functional group. The medical tool has the surface lubricity in wetting, where the compounds having the thiol groups are carried by the base material layer by radiating ionized gas plasma containing nitrogen and also the surface lubricating layers are joined with the base material layers by reacting the compounds having the thiol groups with the hydrophilic polymers with the reactive function group.
摘要翻译：要解决的问题：提供一种用于通过以简单的方法牢固地固定各种聚合物基材和表面润滑层来在使用期间永久地显示出优异表面润滑性的医疗工具。解决方案：医疗工具包括：至少在表面上包含聚合材料的基材层; 化合物各自由至少一部分基材层承载，并且在分子中具有多个硫醇基; 和表面润滑层，其各自覆盖分子中具有多个硫醇基的化合物，并且包含具有反应性官能团的亲水性聚合物。医疗用具具有表面润湿性，其中具有硫醇基的化合物通过辐射含有氮的离子化气体等离子体而被基材层承载，并且表面润滑层通过使具有硫醇基团与亲水性聚合物与反应性官能团。版权所有（C）2012，JPO＆INPIT

5. 发明专利

JP2013192885A Medical implement and method for producing the same 审中-公开
标题翻译：医疗实施方法及其生产方法
公开(公告)号：JP2013192885A
公开(公告)日：2013-09-30
申请号：JP2012065973
申请日：2012-03-22
申请人： Terumo Corp , テルモ株式会社
发明人： SHINODA SAYAKA , OMATA RIKIYA
IPC分类号： A61L29/00 , A61L31/00 , A61M25/00 , A61M25/09
摘要： PROBLEM TO BE SOLVED: To provide a medical implement including a surface lubricant layer having island-shaped projecting parts to exert excellent water holding properties, and to provide a method for producing the same.SOLUTION: A method for producing a medical implement includes processes of preparing a solution B by adding hydrophilic polymers and a substance A into a solvent soluble to the hydrophilic polymer and insoluble to the substance A, and forming a film on a base material layer by coating the base material layer with the solution B, and forming a surface lubricant layer having island-shaped projecting parts by immersing the base material layer formed with the film into a solution C insoluble to the hydrophilic polymer and soluble to the substance A. An average particle diameter of the substance A exceeds a thickness of the film formed on the base material layer.
摘要翻译：要解决的问题：提供一种包括具有岛状突出部分的表面润滑剂层以发挥优异的保水性的医疗器具，并提供其制造方法。解决方案：一种医疗器具的制造方法，包括以下步骤：通过将亲水性聚合物和物质A添加到可溶于亲水性聚合物的溶剂中并且不溶于物质A来制备溶液B，并通过用溶液B涂覆基材层而在基材层上形成膜，并形成通过将由膜形成的基材层浸渍在不溶于亲水性聚合物并溶解于物质A的溶液C中，形成岛状突起部的表面润滑剂层。物质A的平均粒径超过形成的膜的厚度在基材层上。

6. 发明专利

JP2013150656A Lumen insertion tool and method for manufacturing the same 有权
标题翻译： LUMEN插入工具及其制造方法
公开(公告)号：JP2013150656A
公开(公告)日：2013-08-08
申请号：JP2012011920
申请日：2012-01-24
申请人： Terumo Corp , テルモ株式会社
发明人： OMATA RIKIYA , SHINODA SAYAKA
IPC分类号： A61M25/14 , A61M25/00 , A61M25/09
摘要： PROBLEM TO BE SOLVED: To provide a method for manufacturing a lumen insertion tool which has a surface lubricating layer having minute voids and exhibits excellent lubrication maintenability.SOLUTION: A method for manufacturing a lumen insertion tool 10 includes steps of: coating a base material layer 1 with a coating solution containing hydrophilic polymer and microbubbles; and drying the base material layer 1 coated with the coating solution and forming a surface lubricating layer 2 with voids 3. The microbubbles have an average diameter of 50-5,000 nm, and are contained in the coating solution at 10-10bubbles/mL. The lumen insertion tool 10 has the base material layer 1 and the surface lubricating layer 2 carried on at least a part of the base material layer 1. The tool has 1-1,000 voids 3 per mmhaving an average diameter of 50-5,000 nm in the surface lubricating layer 2.
摘要翻译：要解决的问题：提供一种具有具有微小空隙的表面润滑层并且具有优异的润滑稳定性的管腔插入工具的制造方法。解决方案：一种用于制造内腔插入工具10的方法，包括以下步骤：将基材层 1与含有亲水性聚合物和微泡的涂布溶液; 并干燥涂覆有涂层溶液的基材层1并形成具有空隙3的表面润滑层2.微泡的平均直径为50-5,000nm，以10-10巴/ mL的比例包含在涂布溶液中。管腔插入工具10具有基材层1和承载在基材层1的至少一部分上的表面润滑层2.该工具在平均直径为50-5,000nm的范围内具有1-1000个空隙3，平均直径为50-5,000nm 表面润滑层2。

7. 发明专利

JP2011245102A Medical tool whose surface has lubricability when getting wet 有权
标题翻译：表面湿润时表面具有润滑性的医用工具
公开(公告)号：JP2011245102A
公开(公告)日：2011-12-08
申请号：JP2010122853
申请日：2010-05-28
申请人： Terumo Corp , テルモ株式会社
发明人： SAWADA KENJI , OMATA RIKIYA , SHINODA SAYAKA , ANZAI TAKAKIMI
IPC分类号： A61L29/00 , A61L31/00
摘要： PROBLEM TO BE SOLVED: To provide a medical tool permanently exhibiting excellent surface lubricability when using by strongly fixing various kinds of polymer base materials and a surface lubricating layer in a simpler technique.SOLUTION: The medical tool whose surface has lubricability when getting wet has: a base material layer at least a surface of which comprises a polymer material; a compound carried on at least a part of the base material layer and having a plurality of thiol groups in a molecule; and the surface lubricating layer covering the compound having the plurality of thiol groups in the molecule and comprising a hydrophilic polymer having reactive functional groups, wherein the medical tool is characterized in that the compound having the thiol groups is carried on the base material layer by emitting ionized gas plasma including oxygen, and the surface lubricating layer is bonded to the base material layer by reacting the compound having the thiol groups and the hydrophilic polymer having the reactive functional groups.
摘要翻译：要解决的问题：提供一种在简单的技术中强力固定各种聚合物基材和表面润滑层的使用时，永久表现出优异的表面润滑性的医疗工具。解决方案：表面在变湿时具有润滑性的医疗工具具有至少一个表面包含聚合物材料的基材层; 在基材层的至少一部分上承载并在分子中具有多个硫醇基的化合物; 并且所述表面润滑层覆盖在分子中具有多个硫醇基的化合物，并且包含具有反应性官能团的亲水性聚合物，其中所述医疗工具的特征在于，具有硫醇基的化合物通过发射被承载在基材层上包括氧的离子化气体等离子体，并且通过使具有硫醇基的化合物和具有反应性官能团的亲水性聚合物反应，将表面润滑层与基材层接合。版权所有（C）2012，JPO＆INPIT

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