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1. 发明专利

JP2010053062A Oral cavity composition 审中-公开
标题翻译：口腔组成
公开(公告)号：JP2010053062A
公开(公告)日：2010-03-11
申请号：JP2008218964
申请日：2008-08-28
申请人： Sunstar Inc , サンスター株式会社
发明人： SAITO TORU , SHIMIZU YASUMITSU , HAYASHI YOSHIKO
IPC分类号： A61K35/74 , A23G4/00 , A23L1/30 , A61K8/99 , A61P1/02 , A61Q11/00
摘要： PROBLEM TO BE SOLVED: To provide an oral cavity composition used for preventing and treating oral diseases while inhibiting the growth of pathogenic bacteria present in the oral cavity including a biofilm formed in the oral cavity. SOLUTION: The incorporation of lactic acid bacteria belonging to the genus Leuconostoc into an oral cavity composition causes co-aggregation of the main oral cavity bacteria which form a biofilm in the oral cavity and allows such lactic acid bacteria to attach to the oral cavity mucosa and to be fixed in the oral cavity and as a result, the prevention and treatment of oral diseases can be carried out while efficiently inhibiting the growth of the pathogenic bacteria present in the oral cavity. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：待解决的问题：提供用于预防和治疗口腔疾病的口腔组合物，同时抑制口腔中存在的病原细菌的生长，包括在口腔中形成的生物膜。解决方案：将属于明串珠菌属的乳酸菌掺入口腔组合物中导致在口腔中形成生物膜的主要口腔细菌的共聚集，并允许这样的乳酸菌附着于口腔腔粘膜并固定在口腔中，结果可以在有效抑制存在于口腔中的致病菌的生长的同时进行口腔疾病的预防和治疗。版权所有（C）2010，JPO＆INPIT

2. 发明专利

JP2014187948A Crushed fruit product with suppressed change in color tone, and manufacturing method thereof 有权
标题翻译：具有抑制变色的粉碎水果产品及其制造方法
公开(公告)号：JP2014187948A
公开(公告)日：2014-10-06
申请号：JP2013067286
申请日：2013-03-27
申请人： Sunstar Inc , サンスター株式会社
发明人： YASUDA NAOMI , SHIMIZU YASUMITSU , SUIDO HIROHISA
IPC分类号： A23L2/02 , A23L2/00
摘要： PROBLEM TO BE SOLVED: To provide a fruit skin-mixed crushed fruit product with significantly suppressed change in appearance during heating in manufacturing or during storage and a manufacturing method thereof; and a beverage composition blended with the fruit skin-mixed crushed fruit product.SOLUTION: Due to fermentation treatment of a fruit skin-mixed crushed fruit product with lactic acid bacteria of genus lactobacillus, the storage stability (suppressed change in appearance and suppressed change in flavor) of the fruit skin-mixed crushed fruit product is significantly enhanced. In addition, a beverage composition blended with the fruit skin-mixed crushed fruit product also has significant improvement in the color change due to heating in manufacturing and in the appearance change due to storage of the product.
摘要翻译：要解决的问题：提供在制造或储存期间加热期间显着抑制外观变化的水果皮混合碎果产品及其制造方法; 与水果皮混合粉碎水果制品混合的饮料组合物。解决方案：由于乳酸杆菌乳酸菌与水果皮混合粉碎水果产品的发酵处理，储存稳定性（抑制外观变化和抑制变化风味）的水果皮混合粉碎水果产品显着增强。此外，与水果皮混合的破碎水果产品混合的饮料组合物也由于制造中的加热和由于产品的储存引起的外观变化而引起的颜色变化的显着改善。

3. 发明专利

JP2005104911A Oral composition 审中-公开
标题翻译：口腔组成
公开(公告)号：JP2005104911A
公开(公告)日：2005-04-21
申请号：JP2003341057
申请日：2003-09-30
申请人： Sunstar Inc , サンスター株式会社
发明人： SHIMIZU YASUMITSU , KOBAYASHI TOSHIMI , IMANAKA HIROSANE
IPC分类号： A61K8/40 , A61K8/00 , A61K8/20 , A61K8/23 , A61K8/34 , A61K8/36 , A61K8/365 , A61K8/44 , A61Q11/00 , A61K7/22 , A61K7/16 , A61K7/24
摘要： PROBLEM TO BE SOLVED: To obtain an oral composition having excellent sense of use by reducing bitterness derived from a quaternary ammonium salt-type antimicrobial agent and an anti-plasmin agent such as tranexamic acid without reducing the drug actions of them.
SOLUTION: The oral composition contains the quaternary ammonium salt-type antimicrobial agent and/or the tranexamic acid, and a water-soluble calcium salt.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：待解决的问题：通过降低源自季铵盐型抗微生物剂和抗纤维蛋白溶解剂如氨甲环酸的苦味来获得具有优异使用感的口服组合物，而不会降低药物作用。口服组合物含有季铵盐型抗微生物剂和/或氨甲环酸，以及水溶性钙盐。版权所有（C）2005，JPO＆NCIPI

4. 发明专利

JP2004026816A Composition for oral cavity 审中-公开
公开(公告)号：JP2004026816A
公开(公告)日：2004-01-29
申请号：JP2003128936
申请日：2003-05-07
申请人： Sunstar Inc , サンスター株式会社
发明人： SHIMIZU YASUMITSU , KISHIMOTO SHUICHI , NAKAMURA TOMOMI , MATSUURA MASAHIRO , NAESHIRO HIDEKAZU
IPC分类号： A61K8/00 , A61K8/20 , A61K8/24 , A61K8/25 , A61K8/33 , A61K8/34 , A61K8/36 , A61K8/365 , A61K8/46 , A61K8/49 , A61K8/60 , A61K8/64 , A61K8/66 , A61K8/73 , A61K8/86 , A61K8/97 , A61Q11/00 , A61K7/16
摘要： PROBLEM TO BE SOLVED: To obtain a new tablet type composition for applying to the oral cavity, quickly dispersed with saliva when the composition is put in mouth, cleaned by using a teeth brush, or the like, and imparted with excellent feeling in use in the oral cavity by adding a binding agent and a foaming (whipping) agent in a proper ratio.
SOLUTION: A sugar alcohol and a disintegrating agent are added to an abrasive, the foaming (whipping) agent, the binding agent and a humectant by combining them in a specific ratio.
COPYRIGHT: (C)2004,JPO

5. 发明专利

JP2014187949A Fermented fig product and beverage blended therewith 审中-公开
标题翻译：发酵图形和饮料混合
公开(公告)号：JP2014187949A
公开(公告)日：2014-10-06
申请号：JP2013067287
申请日：2013-03-27
申请人： Sunstar Inc , サンスター株式会社
发明人： YASUDA NAOMI , SHIMIZU YASUMITSU , SUIDO HIROHISA
IPC分类号： A23L19/00 , A23L2/38 , A23L2/52
摘要： PROBLEM TO BE SOLVED: To provide a lactic acid bacteria-fermented product made from crushed product of whole fruit fig, having enhanced antioxidative activity of the crushed product of whole fruit fig; and a beverage which contains the lactic acid bacteria-fermented product.SOLUTION: A crushed product of whole fruit fig is fermented with use of Lactobacillus pentosus, so that a fermented product having an enhanced antioxidative activity is produced. A container-packaged beverage is made from the fermented product.
摘要翻译：要解决的问题：提供由全果无花果粉碎产品制成的乳酸菌发酵产品，具有增强整个无花果粉碎产品的抗氧化活性; 和含有乳酸菌发酵产品的饮料。解决方案：使用乳酸乳杆菌发酵全果无花果的粉碎产物，从而产生具有增强的抗氧化活性的发酵产品。容器包装的饮料由发酵产品制成。

6. 发明专利

JP2006241122A Recalcification-promoting composition 有权
标题翻译：回收促进组合物
公开(公告)号：JP2006241122A
公开(公告)日：2006-09-14
申请号：JP2005062693
申请日：2005-03-07
申请人： Sunstar Inc , サンスター株式会社
发明人： YASUDA TAKAKO , TAKATSUKA TSUTOMU , SHIMIZU YASUMITSU
IPC分类号： A61K8/21 , A23G3/34 , A23L1/30 , A61Q11/00
摘要： PROBLEM TO BE SOLVED: To provide a composition enabling teeth recalcification to be promoted. SOLUTION: The recalcification-promoting composition comprises glucosamine and/or chitosan oligosaccharide and a fluorine ion-releasing substance. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供能够促进牙齿再钙化的组合物。解淀粉促进组合物包含葡糖胺和/或壳聚糖寡糖和氟离子释放物质。版权所有（C）2006，JPO＆NCIPI

7. 发明专利

JPH07267867A TREATING AGENT HAVING ANTIENDOTOXIN ACTIVITY 失效
公开(公告)号：JPH07267867A
公开(公告)日：1995-10-17
申请号：JP8590394
申请日：1994-03-30
申请人： SUNSTAR INC
发明人： SHIMIZU YASUMITSU , FUJII YUKO , EGUCHI TORU
IPC分类号： A61K9/00 , A61K8/00 , A61K8/49 , A61K9/70 , A61K31/70 , A61P1/02 , A61P9/00 , A61Q11/00 , A61K31/71 , A61K7/16
摘要： PURPOSE:To obtain the subject agent capable of efficiently neutralizing an endotoxin released by a gram-negative bacterium and useful as a treating agent for endotoxin shock, a pretreating agent for e.g. a regeneration treatment of periodontal tissue, etc. CONSTITUTION:This is a toxin inhibitor against an endotoxin of a gram-negative bacterium containing a macrolide antibiotic having a 14-membered ring, preferably at least one kind selected from an erythromycin, a clarithromycin, a triacetyloleandomycin and a roxithromycin. In the case of medical use, this inhibitor is preferably used as an oral preparation or an injection which is a directly administrable preparation, i.e., an intravenous injection and in the case of dental use, as an ointment or a film which has sustained releasability and is directly administrable into a periodontal pocket. In the case of oral preparation which is systemically administered, a preferable dose is 300-1500mg/ day and in the case of an external preparation, etc., which is topically administered, 15mg/day.

8. 发明专利

JP2003238391A SUSTAINED RELEASE OINTMENT OF LOCAL ADMINISTRATION TYPE 审中-公开
公开(公告)号：JP2003238391A
公开(公告)日：2003-08-27
申请号：JP2002041638
申请日：2002-02-19
申请人： SUNSTAR INC
发明人： TOKIOKA KYOHEI , SHIMIZU YASUMITSU
IPC分类号： A61K9/06 , A61K9/00 , A61K31/65 , A61K47/06 , A61K47/08 , A61K47/14 , A61K47/30 , A61K47/34 , A61P1/02 , A61P31/04
摘要： PROBLEM TO BE SOLVED: To provide a sustained release ointment having character suitable for administration using a syringe, instantaneously solidifiable upon contacting with water after administered, and also stably compoundable with an unstable biologically active medicament such as a tetracycline-based antibiotic, to provide a method for producing the ointment, and to provide a kit for treating periodontal diseases enabling the ointment to easily be administered into periodontal pockets using a syringe. SOLUTION: The sustained release ointment of local administration type comprises a biodegradable polymer, a polyethylene glycol and a biologically active medicament. This ointment has such a property as to be instantaneously solidified upon contacting with water. The method for producing the ointment comprises the steps of heating both the biodegradable polymer and the polyethylene glycol to 70-120°C to effect liquefaction and homogeneously mixing them together. The kit for treating periodontal diseases is obtained by encapsulating the ointment into a syringe for administering it into periodontal pockets. COPYRIGHT: (C)2003,JPO

9. 发明专利

JPH06287133A NON-AQUEOUS PASTY COMPOSITION FOR ORAL CAVITY APPLICATION 失效
公开(公告)号：JPH06287133A
公开(公告)日：1994-10-11
申请号：JP9852993
申请日：1993-03-31
申请人： SUNSTAR INC
发明人： SHIMIZU YASUMITSU , YOSHIMURA MIKIKO , EGUCHI TORU
IPC分类号： A61K8/00 , A61K8/20 , A61K8/23 , A61K8/34 , A61K8/36 , A61K8/365 , A61K8/73 , A61K9/06 , A61Q11/00 , A61K7/16
摘要： PURPOSE:To provide a non-aqueous pasty composition exhibiting excellent adhesion and retention on the mucosa of oral cavity, having proper extensibility and resistant to discoloration with heat. CONSTITUTION:The non-aqueous pasty composition for oral cavity application is produced by compounding a calcium salt and/or a barium salt to a non- aqueous pasty composition composed of glycerol and/or ethylene glycol and a water-soluble polymeric compound having hydroxyl group (one or more kinds of compounds selected from carboxymethyl cellulose sodium, sodium alginate, polyvinyl alcohol, carrageenan, locust bean gum, guar gum, hydroxymethylcellulose, hydroxyethylcellulose, xanthan gum, tragacanth gum, starch and succinoglucan).

10. 发明专利

JP2000107298A MEDICAMENT INJECTOR 失效
公开(公告)号：JP2000107298A
公开(公告)日：2000-04-18
申请号：JP28390998
申请日：1998-10-06
申请人： NISSHO KK , SUNSTAR INC
发明人： HIRAYAMA TOSHIKAZU , HASEGAWA SHUJI , TOCHIYAMA TOSHIO , EGUCHI TORU , SHIMIZU YASUMITSU , YONEDA JUNKO
IPC分类号： A61C19/06 , A61M5/32 , A61M5/34 , A61M35/00
摘要： PROBLEM TO BE SOLVED: To improve convenience by fitting a nozzle so as to be freely attachable/detachable, which consists of an attaching part at the side of a base end provided with an attaching means to a nozzle fitting part and of a discharge part extending from the attaching part after bending by a prescribed angle in a barrel where the nozzle fitting part is disposed at a tip and a gasket is fitted inside. SOLUTION: A medicament injector is provided with the barrel 1 having the nozzle fitting part 11 at its tip, a plunger 2 having the gasket 21 at its tip and the nozzle 3 being freely attachable/detachable in the nozzle fitting part 11 and the nozzle 3 is constituted of the attaching part 31 to the barrel 1 and the discharge part 32 extending from the attaching part 31 after bending by a prescribed angle. The barrel 1 is provided with the flange 12 at the base end, by which fingers are hooked at the time of an injecting operation, and is formed by providing a tip 111 by which the nozzle fitting part 11 is fitted to the inner cavity 312 of the attaching part 31 in the nozzle 3 and a female screw 112 to be screwed onto a male screw 311 arranged at the base end of the nozzle 3. The plunger 2 is provided with the gasket 21 at the tip of a plunger rod 22 and inserted from the rear end of the barrel 1.

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