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1. 发明专利

JP2014014485A Biological information analysis device, imaging device, light source device and method for operating biological information analysis device 审中-公开
标题翻译：生物信息分析装置，成像装置，光源装置和操作生物信息分析装置的方法
公开(公告)号：JP2014014485A
公开(公告)日：2014-01-30
申请号：JP2012153553
申请日：2012-07-09
申请人： Sumitomo Electric Ind Ltd , 住友電気工業株式会社
发明人： AKAHANE YOSHIHIRO , NAKAMURA TAKAO , MATSUURA TAKASHI , IKEGAMI TAKATOSHI , AWAZU KUNIO , HAZAMA HISANAO
IPC分类号： A61B5/1455 , A61B5/1459 , H01S5/343
摘要： PROBLEM TO BE SOLVED: To provide a technology capable of more accurately analyzing biological information.SOLUTION: A biological information analysis device 100 has an imaging device 2, an analysis part 3, an input part 4, and a display part 5. The imaging device 2 radiates illumination light to an analysis object 1, and images the analysis object 1. The analysis object 1 may be a biological tissue extracted from a living body, and may be tissue in the living body. A light source device 10 includes a laser light source 11, a driver 12, a temperature adjustment part 13, and a light source control part 14 for controlling the driver 12 and the temperature adjustment part 13. A green semiconductor laser is used as the laser light source 11. The wavelength of a laser beam can be easily changed by changing an operation temperature in the semiconductor laser. Thereby, the accuracy of analysis of biological information can be enhanced.
摘要翻译：要解决的问题：提供能够更准确地分析生物信息的技术。解决方案：生物信息分析装置100具有成像装置2，分析部3，输入部4和显示部5.成像装置 2将照明光照射到分析对象1，并对分析对象1进行成像。分析对象1可以是从活体提取的生物组织，并且可以是生物体中的组织。光源装置10包括激光光源11，驱动器12，温度调节部13和用于控制驱动器12和温度调节部13的光源控制部14.作为激光使用绿色半导体激光光源11.通过改变半导体激光器中的工作温度，可以容易地改变激光束的波长。从而可以提高生物信息的分析精度。

2. 发明专利

JP2008086402A Medical treatment apparatus and medical treatment method 审中-公开
标题翻译：医疗处理设备和医疗处理方法
公开(公告)号：JP2008086402A
公开(公告)日：2008-04-17
申请号：JP2006268130
申请日：2006-09-29
申请人： Sumitomo Electric Ind Ltd , 住友電気工業株式会社
发明人： HATAYAMA HITOSHI , INOUE SUSUMU , SUGANUMA HIROSHI , AWAZU KUNIO
IPC分类号： A61N5/06
摘要： PROBLEM TO BE SOLVED: To provide a medical treatment apparatus and a medical treatment method for obtaining a highly reliable medical treatment effect.
SOLUTION: The medical treatment apparatus 1 is equipped with: an excitation part 2 for outputting excitation light; a medical treatment part 3 for irradiating a lesion F with light for evaporation and treating it; an illumination part 4 for illuminating the lesion F; a fluorescence detection part 5 for detecting fluorescence S; an imaging part 6 for imaging the lesion F; and an output control part 7 for controlling the output power of light emitted from the excitation part 2 and the medical treatment part 3. The specified wavelength λ
2 of the light for evaporation is in the range of 400 to 420 nm. The output control part 7 changes the output power of the light emitted from the first light emitting part 20 of the excitation part 2 and the second light emitting part 30 of the medical treatment part 3 with time.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：解决的问题：提供一种医疗处理装置和医疗处理方法，以获得高度可靠的医疗效果。解决方案：医疗装置1配备有用于输出激发光的激励部2; 用于通过光照射病变F以进行蒸发处理的医疗处理部分3; 用于照射病变F的照明部分4; 用于检测荧光S的荧光检测部5; 用于对病变F进行成像的成像部6; 以及用于控制从激励部分2和医疗处理部分3发射的光的输出功率的输出控制部分7.用于蒸发的光的指定波长λ 2 在400至 420nm。输出控制部7随时间改变从治疗部3的激发部2和第二发光部30的第一发光部20发射的光的输出功率。版权所有（C）2008，JPO＆INPIT

3. 发明专利

JP2008220361A Method of differentiation induction to osteoblast 有权
标题翻译：差异诱导OSTEOBLAST的方法
公开(公告)号：JP2008220361A
公开(公告)日：2008-09-25
申请号：JP2007217174
申请日：2007-08-23
申请人： Sumitomo Electric Ind Ltd , 住友電気工業株式会社
发明人： KUSHIBIKI TOSHIHIRO , AWAZU KUNIO , INOUE SUSUMU , SUGANUMA HIROSHI , HATAYAMA HITOSHI
IPC分类号： A61L27/00 , C12N5/077 , C12N15/09
CPC分类号： C12N5/0654 , C12N2506/1353 , C12N2529/10
摘要： PROBLEM TO BE SOLVED: To provide a technique for selectively differentiation-inducing mesenchymal stem cells, which can differentiate to cells that constitute various tissues and organs, to osteoblasts, and to provide a technique for differentiation-inducing mesenchymal stem cells to osteoblasts with a simple operation that needs only short time and that is noninvasive. SOLUTION: The inventors have found that the switch for the differentiation induction to osteoblasts is turned on by translocating biological clock-relevant factors existing in mesenchymal stem cells from the cells' cytoplasm to the cells' nucleus. The inventors have also found that the switch can be turned on by irradiating the cells for a short time with a light that is noninvasive. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种选择性分化诱导间充质干细胞的技术，其可以分化成构成各种组织和器官的细胞，成骨细胞，并提供用于分化诱导间充质干细胞成骨细胞的技术一个简单的操作只需要很短的时间，这是无创的。解决方案：本发明人已经发现，通过将存在于间充质干细胞中的生物钟相关因子从细胞质细胞转移到细胞核来开启分化诱导成骨细胞的转换。本发明人还发现，通过用非侵入性的光照射短时间的电池可以开启开关。版权所有（C）2008，JPO＆INPIT

4. 发明专利

JP2014014486A Laser treatment device, and operation method and therapeutic method of laser treatment device 审中-公开
标题翻译：激光治疗装置，以及激光治疗装置的操作方法和治疗方法
公开(公告)号：JP2014014486A
公开(公告)日：2014-01-30
申请号：JP2012153554
申请日：2012-07-09
申请人： Sumitomo Electric Ind Ltd , 住友電気工業株式会社
发明人： AKAHANE YOSHIHIRO , NAKAMURA TAKAO , MATSUURA TAKASHI , IKEGAMI TAKATOSHI , AWAZU KUNIO , HAZAMA HISANAO
IPC分类号： A61F9/008
摘要： PROBLEM TO BE SOLVED: To provide technology for determining a suitable irradiation amount of laser beams in a laser treatment device for performing the medical treatment by irradiating a laser beam to an affected part.SOLUTION: A laser treatment device 100 includes: a therapeutic laser light source 10; a monitor laser light source 11; a photo detecting part 12; a control part 2; an optical system 3; an input part 4; and an output part 6. The therapeutic laser light source 10 generates therapeutic laser light. The therapeutic laser light is irradiated to an affected part of a patient's eye 1 through the optical system 3. The monitor laser light source 11 emits monitor laser light for illuminating the interior of the patient's eye 1. The photo detecting part 12 receives the monitor laser light reflected at the ocular fundus of the patient's eye 1 through the optical system 3 to detect the intensity of the reflected light. The control part 2 compares the intensity of the reflected light detected by the photo detecting part with a reference intensity. When the detected intensity reaches the reference intensity, the control part 2 determines the end of medical treatment.
摘要翻译：要解决的问题：提供用于通过向受影响的部位照射激光来进行医疗处理的激光治疗装置中的激光束的合适的照射量的技术。解决方案：激光治疗装置100包括：治疗用激光来源10; 监视器激光光源11; 光检测部12; 控制部2; 光学系统3; 输入部分4; 和输出部6.治疗用激光光源10产生治疗激光。治疗用激光通过光学系统3照射到患者眼睛1的受影响部位。监视激光光源11发射用于照射患者眼睛1内部的监视激光。光检测部12接收监视激光通过光学系统3在患者眼睛1的眼底反射的光以检测反射光的强度。控制部2将由光检测部检测出的反射光的强度与基准强度进行比较。当检测到的强度达到参考强度时，控制部分2确定医疗结束。

5. 发明专利

JP2004361252A Method of determining phosphorylation of peptide or protein 审中-公开
公开(公告)号：JP2004361252A
公开(公告)日：2004-12-24
申请号：JP2003160157
申请日：2003-06-05
申请人： Sumitomo Electric Ind Ltd , 住友電気工業株式会社
发明人： NAKADA MOTOKI , AWAZU KUNIO
IPC分类号： G01N33/483 , C07K7/06 , G01N21/27 , G01N21/35 , G01N33/68
摘要： PROBLEM TO BE SOLVED: To determine the presence of a peptide or a protein coupled with phosphoric acid in a short time by a simple operation. SOLUTION: A spectrum in an infrared area of the peptide or the protein is measured to determine the presence of the coupling of phosphoric acid with the peptide or the protein, based on a spectrum shape or a peak position in 100-1,100 [cm -1 ] of area. A kind of amino acid is specified in the peptide or the protein coupled with the phosphoric acid. COPYRIGHT: (C)2005,JPO&NCIPI

6. 发明专利

JP2010216945A Analytical method 审中-公开
标题翻译：分析方法
公开(公告)号：JP2010216945A
公开(公告)日：2010-09-30
申请号：JP2009063063
申请日：2009-03-16
申请人： Sumitomo Electric Fine Polymer Inc , Sumitomo Electric Ind Ltd , 住友電工ファインポリマー株式会社 , 住友電気工業株式会社
发明人： KANAZAWA SHINICHI , NAKADA MOTOMI , NAKABAYASHI MAKOTO , AWAZU KUNIO , HAZAMA HISANAO
IPC分类号： G01N27/64 , G01N27/62 , H01J49/14
摘要： PROBLEM TO BE SOLVED: To provide a means for analyzing high molecular substances such as polypeptides, proteins, and glucose without having to mix them with a matrix substance.
SOLUTION: An analyte of proteins and polypeptides or cells and biological tissue containing them is mounted to a resin sheet made of, for example, a cyclic polyolefin, an aromatic nylon, and a polycarbonate. The analyte mounted on the resin sheet is irradiated with an infrared laser beam to ionize the analyte and perform detection by mass analysis.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供用于分析高分子物质如多肽，蛋白质和葡萄糖的方法，而不必将其与基质物质混合。解决方案：将蛋白质和多肽或细胞的分析物和含有它们的生物组织安装到由例如环状聚烯烃，芳香族尼龙和聚碳酸酯制成的树脂片上。用红外激光束照射安装在树脂片上的分析物，使分析物离子化，通过质量分析进行检测。版权所有（C）2010，JPO＆INPIT

7. 发明专利

JP2006038614A Phosphorylation analyzer of peptide or protein, phosphorylation determination program and recording medium of program 有权
标题翻译：肽或蛋白质的磷酸化分析仪，磷化测定程序和程序记录介质
公开(公告)号：JP2006038614A
公开(公告)日：2006-02-09
申请号：JP2004218308
申请日：2004-07-27
申请人： Sumitomo Electric Ind Ltd , 住友電気工業株式会社
发明人： NAKADA MOTOMI , AWAZU KUNIO
IPC分类号： G01N33/483 , G01N21/35
CPC分类号： G01N21/35 , G01N21/3577
摘要： PROBLEM TO BE SOLVED: To provide a phosphorylation analyzer for discrimination whether phosphoric acid is bonded to a peptide or a protein or not in a short time by a simple operation, a phosphorylation determination program and a recording medium recording the program. SOLUTION: A spectrum in an infrared domain of a peptide or a protein is measured, and the kind of an amino acid of the peptide or the protein to which phosphorylation phosphoric acid is bonded is specified from a peak position of the spectrum in the domain of 1,000-1,100 cm -1 . COPYRIGHT: (C)2006,JPO&NCIPI

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