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    • 1. 发明专利
    • Organic field effect transistor and production method therefor
    • 有机场效应晶体管及其生产方法
    • JP2010062183A
    • 2010-03-18
    • JP2008223369
    • 2008-09-01
    • Osaka UnivShin-Etsu Chemical Co Ltd信越化学工業株式会社国立大学法人大阪大学
    • TANIGUCHI MASATERUKAWAI TOMOJIKAWAGUCHI HIDEYUKIFUKUI IKUO
    • H01L29/786H01L51/05H01L51/30
    • H01L51/052H01L51/0036H01L51/004H01L51/0043H01L51/0545
    • PROBLEM TO BE SOLVED: To provide an OFET operated at a low voltage equivalent to ordinary amorphous silicon by turning both of semiconductor layer and insulator layer materials to an organic compound and forming the insulator layer using a mixed system of a polymer material which has a high relative dielectric constant and which does not have a hydroxyl group and a polymerizable and/or crosslinkable organic compound other than that as a material for forming the insulator layer, in a TFT having a structure of a conductor layer/an insulator layer/a semiconductor layer. SOLUTION: In the organic field effect transistor having the structure of the conductor layer/the insulator layer/the semiconductor layer, the organic field effect transistor includes the insulator layer formed by mixing the polymer material obtained by polymerizing or copolymerizing a monomer represented by the formula (1): CH 2 =CHCOO-(CH 2 ) 2 -CN and/or (2): CH 2 =C(CH 3 )COO-(CH 2 ) 2 -CN with the polymerizable and/or crosslinkable organic compound other than the monomer represented by the formulas (1) and (2), and the semiconductor layer comprising the organic compound. COPYRIGHT: (C)2010,JPO&INPIT
    • 要解决的问题:为了提供通过将半导体层和绝缘体层材料两者都转化为有机化合物的等效于普通非晶硅的低电压操作的OFET,并使用聚合物材料的混合系统形成绝缘体层, 具有高的相对介电常数,并且在具有导体层/绝缘体层/结构的结构的TFT中,除了作为形成绝缘体层的材料之外,不具有羟基和聚合性和/或可交联的有机化合物, 半导体层。 解决方案:在具有导体层/绝缘体层/半导体层的结构的有机场效应晶体管中,有机场效应晶体管包括通过将通过聚合或共聚所表示的单体获得的聚合物材料混合而形成的绝缘体层 通式(1)表示:CH 2 = CHCOO-(CH 2 )SB -CN和/或(2):CH 2 2 除了由式(1)和(2)表示的单体以外的化合物,以及包含有机化合物的半导体层。 版权所有(C)2010,JPO&INPIT
    • 2. 发明专利
    • Solid preparation containing enteric solid dispersion
    • 含固体分散体的固体制剂
    • JP2013047258A
    • 2013-03-07
    • JP2012240328
    • 2012-10-31
    • Shin-Etsu Chemical Co Ltd信越化学工業株式会社
    • HOSHINO TAKASHIKUSAKI FUMIEFUKUI IKUO
    • A61K47/38A61K9/16A61K9/20A61K47/32
    • PROBLEM TO BE SOLVED: To provide a solid preparation containing an enteric solid dispersion rapidly dissolving a drug in the preparation without damaging the dissolution properties of the solid preparation, or a method for preparing the same.SOLUTION: The solid preparation comprising a soluble drug, an enteric polymer, an excipient and a disintegrator comprises a granular product wherein a mixed powder comprising at least the excipient and the disintegrator is partly or entirely covered with the solid dispersion comprising a hardly soluble drug and the enteric polymer. The invention provides the solid preparation in which the release of the hardly soluble drug in the stomach is suppressed so that the dissolution rate of the hardly soluble drug using the Japanese Pharmacopoeia first liquid (artificial gastric fluid) after 120 minutes elapse is 10 mass% or less of the initial concentration of the drug administered, or a method for producing the same.
    • 待解决的问题:提供一种固体制剂,其含有快速溶解药物的肠溶固体分散体,而不损害固体制剂的溶解性能,或其制备方法。 解决方案:包含可溶性药物,肠溶性聚合物,赋形剂和崩解剂的固体制剂包括颗粒产品,其中至少包含赋形剂和崩解剂的混合粉末部分或完全被固体分散体覆盖,所述固体分散体包含几乎不含 可溶性药物和肠溶性聚合物。 本发明提供了抑制难溶性药物在胃中的释放的固体制剂,使得使用日本药典第一液体(人造胃液)的120分钟后难溶性药物的溶出速度为10质量% 所用药物的初始浓度较少,或其制备方法。 版权所有(C)2013,JPO&INPIT
    • 3. 发明专利
    • Solid dispersion preparation
    • 固体分散体制备
    • JP2013147512A
    • 2013-08-01
    • JP2013098337
    • 2013-05-08
    • Shin-Etsu Chemical Co Ltd信越化学工業株式会社
    • HOSHINO TAKASHIKUSAKI FUMIEFUKUI IKUO
    • A61K9/16A61K31/4422A61K47/32A61K47/38A61P9/12
    • PROBLEM TO BE SOLVED: To provide a granular preparation or a tablet preparation of a solid dispersion capable of rapidly eluting a medicine in the preparation without damaging the elution property of the solid dispersion.SOLUTION: There is provided a granular preparation of a solid dispersion containing a hardly soluble medicine, a water-soluble polymer, an excipient and a disintegrating agent, the content of the water-soluble polymer being 1 to 10 mass% and the content of the disintegrating agent being 15 to 50 mass%. There is also provided a tablet preparation of the solid dispersion containing the hardly soluble medicine, water-soluble polymer, excipient and disintegrating agent, the content of the water-soluble polymer being 1 to 5 mass% and the content of the disintegrating agent being 15 to 50 mass%.
    • 要解决的问题:提供能够在制剂中快速洗脱药物而不损害固体分散体的洗脱性能的固体分散体的颗粒制剂或片剂制剂。溶液:提供含有 难溶性药物,水溶性聚合物,赋形剂和崩解剂,水溶性聚合物的含量为1〜10质量%,崩解剂的含量为15〜50质量%。 还提供了含有难溶性药物,水溶性聚合物,赋形剂和崩解剂的固体分散体的片剂,水溶性聚合物的含量为1〜5质量%,崩解剂的含量为15 至50质量%。
    • 9. 发明专利
    • Solid preparation of solid dispersion and method for producing the same
    • 固体分散体的固体制备及其制造方法
    • JP2008133259A
    • 2008-06-12
    • JP2007206389
    • 2007-08-08
    • Shin Etsu Chem Co Ltd信越化学工業株式会社
    • HOSHINO TAKASHIKUSAKI FUMIEMARUYAMA NAOAKINISHIYAMA YUICHIFUKUI IKUOUMEZAWA HIROSHI
    • A61K47/38A61K9/14A61K31/4422A61K47/32A61P9/00
    • PROBLEM TO BE SOLVED: To provide a solid preparation comprising a solid dispersion that allows rapid dissolution of a drug in the preparation without lowering the solubility of the solid dispersion, and a method for producing the preparation.
      SOLUTION: The invention provides a solid preparation of a solid dispersion containing a sparingly soluble drug, a water-soluble polymer and a disintegrant, wherein the disintegrant is a low-substituted hydroxypropylcellulose having an average particle diameter of 10-100 μm and a specific surface area of ≥1.0 m
      2 /g determined by the BET method. The invention further provides a method for producing the solid preparation of a solid dispersion comprising the spraying of a water-soluble polymer solution containing a sparingly soluble drug dispersed or dissolved in the solution to a powder mixed with a disintegrant comprising a low-substituted hydroxypropylcellulose having an average particle diameter of 10-100 μm and a specific surface area of ≥1.0 m
      2 /g determined by the BET method, and the granulation and drying of the sprayed product.
      COPYRIGHT: (C)2008,JPO&INPIT
    • 要解决的问题:提供一种固体制剂,其包含固体分散体,其允许药物在制剂中快速溶解而不降低固体分散体的溶解度,以及制备该制剂的方法。 解决方案:本发明提供了含有微溶药物,水溶性聚合物和崩解剂的固体分散体的固体制剂,其中崩解剂是平均粒径为10-100μm的低取代羟丙基纤维素, 通过BET法测定的≥1.0μm 2 / g的比表面积。 本发明还提供一种制备固体分散体的固体制剂的方法,其包括将含有分散或溶解在该溶液中的微溶性药物的水溶性聚合物溶液喷雾到与包含低取代羟丙基纤维素的崩解剂混合的粉末中, 通过BET法测定的平均粒径为10〜100μm,比表面积≥1.0m2 / SP / g,喷雾产物的造粒和干燥。 版权所有(C)2008,JPO&INPIT
    • 10. 发明专利
    • Organic solid electrolyte and secondary battery using this
    • 有机固体电解质和二次电池使用此
    • JP2009009703A
    • 2009-01-15
    • JP2007151262
    • 2007-06-07
    • Shin Etsu Chem Co Ltd信越化学工業株式会社
    • FUKUI IKUO
    • H01M10/052H01M10/0565
    • Y02E60/122Y02T10/7011
    • PROBLEM TO BE SOLVED: To provide an organic solid electrolyte of high ion conductivity which does not react with an electrochemical active material, and a secondary battery using the electrolyte.
      SOLUTION: The organic solid electrolyte is characterized by being composed by compounding a polymer substance which is obtained by polymerizing or copolymerizing a monomer shown by a formula (1) CH
      2 =CHCOO-(CH
      2 )
      2 -CN and/or a monomer shown by a formula (2) CH
      2 =C(CH
      3 )COO-(CH
      2 )
      2 -CN and an inorganic ion salt. Since the organic solid electrolyte uses the polymer substance which has high ion conductivity and has no hydroxide group, there can be provided a secondary battery that is not accompanied the generation of gas in the substance and has a great industrial value when used, for example, as the secondary battery.
      COPYRIGHT: (C)2009,JPO&INPIT
    • 要解决的问题:提供不与电化学活性物质反应的高离子传导性的有机固体电解质和使用电解质的二次电池。 解决方案:有机固体电解质的特征在于通过将通过将式(1)所示的单体聚合或共聚而获得的聚合物物质组成:CH 2 SBB = CHCOO-(CH 3) SB> 2 )和/或由式(2)表示的单体CH 2 = C(CH 3 SB 3) >)COO-(CH 2 )SB 2 -CN和无机离子盐。 由于有机固体电解质使用具有高离子传导性并且不具有氢氧基团的聚合物物质,所以可以提供不伴随物质中产生气体并且在使用时具有很大工业值的二次电池,例如, 作为二次电池。 版权所有(C)2009,JPO&INPIT