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1. 发明专利

JP2008179564A Anti-inflammatory and analgesic plaster 有权
标题翻译：抗炎和分解性塑料
公开(公告)号：JP2008179564A
公开(公告)日：2008-08-07
申请号：JP2007014441
申请日：2007-01-25
申请人： Nichiban Co Ltd , ニチバン株式会社
发明人： OYAMA KUNIHIRO , KAWAHARA KOJI , OTA TOMOKO
IPC分类号： A61K31/192 , A61K9/70 , A61K47/18 , A61K47/32 , A61P29/00
摘要： PROBLEM TO BE SOLVED: To provide an anti-inflammatory and analgesic plaster having excellent skin permeability of felbinac and a good feeling of effects by moderate thermal sensation stimulation, without using a rosin-based resin, crotamiton and 1-menthol acting as a skin sensitizing ingredient or a skin irritating ingredient.
SOLUTION: The anti-inflammatory and analgesic plaster is provided with a pressure-sensitive adhesive layer containing the felbinac and formed on one surface of a support. In the anti-inflammatory and analgesic plaster, the pressure-sensitive adhesive layer comprises (a) a styrene-isoprene-styrene block copolymer, (b) a terpenic resin, (c) a plasticizer, (d) an antioxidant, (e) the felbinac and (f) at least one kind of thermal sensation stimulating ingredient selected from the group consisting of nonylic acid vanillylamide and capsaicin.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：待解决的问题：为了提供具有优良皮肤渗透性的消炎止痛膏，并且通过适度的热感刺激具有良好的效果感，而不使用松香类树脂，克罗他米通和1-薄荷醇作为皮肤致敏成分或皮肤刺激性成分。解决方案：抗炎镇痛膏具有含有联苯乙酸的压敏粘合剂层并形成在载体的一个表面上。在抗炎和止痛膏中，压敏粘合剂层包含（a）苯乙烯 - 异戊二烯 - 苯乙烯嵌段共聚物，（b）萜烯树脂，（c）增塑剂，（d）抗氧化剂，（e）所述联苯乙酸和（f）至少一种选自由壬酸香草酰胺和辣椒素组成的组的热感刺激成分。版权所有（C）2008，JPO＆INPIT

2. 发明专利

JP2005170833A Percutaneous absorption type patch 有权
标题翻译： PERCUTANEOUS吸收型PATCH
公开(公告)号：JP2005170833A
公开(公告)日：2005-06-30
申请号：JP2003412054
申请日：2003-12-10
申请人： Nichiban Co Ltd , ニチバン株式会社
发明人： KAWAHARA YASUSHIGE , OYAMA KUNIHIRO , HONMA TAKEYASU
IPC分类号： A61K9/70 , A61K31/4178 , A61K31/4184 , A61K31/439 , A61K31/538 , A61K47/14 , A61K47/30 , A61K47/32 , A61K47/34 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To prepare a percutaneous absorption type patch of 5-HT
3 receptor antagonist that has excellent skin permeability, storage stability and skin adhesiveness and slight skin irritation.
SOLUTION: This percutaneous absorption type patch is obtained by providing a substrate with an adhesive composition layer containing an adhesive base and a serotonin receptor antagonist. In the percutaneous absorption type patch, the adhesive base is a rubber-based adhesive comprising a styrene-isoprene-styrene block copolymer and a rosin-based tackifier or a crosslinked acrylic adhesive, the serotonin receptor antagonist is a 5-HT
3 receptor antagonist having a hydrochloride structure or a base into which at least a part of the hydrochloride is dissociated, and the adhesive composition comprises a propylene glycol monofatty acid ester.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：制备具有优异的皮肤渗透性，储存稳定性和皮肤粘合性以及轻微皮肤刺激性的5-HT 3 SB 3受体拮抗剂的经皮吸收型贴剂。解决方案：通过向基材提供含有粘合剂基质和5-羟色胺受体拮抗剂的粘合剂组合物层来获得该经皮吸收型贴剂。在经皮吸收型贴剂中，粘合剂基是包含苯乙烯 - 异戊二烯 - 苯乙烯嵌段共聚物和松香类增粘剂或交联丙烯酸粘合剂的橡胶基粘合剂，5-羟色胺受体拮抗剂是5-HT 3 具有盐酸盐结构或碱基的受体拮抗剂，其中至少部分盐酸盐被解离，并且粘合剂组合物包含丙二醇单脂肪酸酯。版权所有（C）2005，JPO＆NCIPI

3. 发明专利

JP2003063955A Percutaneously absorbable plaster 审中-公开
标题翻译： PERCUTANEOUSLY可吸收塑料
公开(公告)号：JP2003063955A
公开(公告)日：2003-03-05
申请号：JP2001259226
申请日：2001-08-29
申请人： Nichiban Co Ltd , ニチバン株式会社
发明人： KAWAHARA YASUSHIGE , OYAMA KUNIHIRO , ARAMOMI YASUHIKO , ISHII KAZUTAKA
IPC分类号： A61K9/70 , A61K47/10 , A61K47/32
摘要： PROBLEM TO BE SOLVED: To provide a percutaneously absorbable plaster of an adhesive tape type, having a good percutaneous absorbability even during the use of a hydrophilic drug, and having a good adhesiveness to a skin.
SOLUTION: In the percutaneous absorbable plaster provided with an adhesive layer containing the drug, on a support body, (1) the drug is hydrophilic and having a logarithmic value of octanol/water distribution coefficient of ≤1.0, (2) the adhesive layer contains, as a base polymer, a styrene-isoprene-styrene block copolymer (SIS), and (3) the adhesive layer contains at least one higher alcohol of 20-50 wt.% selected from the group consisting of oleyl alcohol and lauryl alcohol, based on the whole amount of the adhesive agent.
COPYRIGHT: (C)2003,JPO
摘要翻译：要解决的问题：提供即使在使用亲水性药物时具有良好的经皮吸收能力并且对皮肤具有良好的粘合性的胶带型的经皮吸收性膏药。解决方案：在具有含有药物的粘合剂层的经皮吸收石膏中，在支撑体上，（1）药物是亲水性的，其辛醇/配水系数的对数值为<= 1.0，（2）粘合剂层含有作为基础聚合物的苯乙烯 - 异戊二烯 - 苯乙烯嵌段共聚物（SIS），和（3）粘合剂层含有至少一种选自油醇和月桂醇的20-50重量％的高级醇，基于粘合剂的总量。

4. 发明专利

JP2008259716A Adhesive skin patch 有权
标题翻译：粘合皮肤贴
公开(公告)号：JP2008259716A
公开(公告)日：2008-10-30
申请号：JP2007105398
申请日：2007-04-13
申请人： Nichiban Co Ltd , ニチバン株式会社
发明人： OYAMA KUNIHIRO , OTA TOMOKO
IPC分类号： A61F13/02
摘要： PROBLEM TO BE SOLVED: To provide an adhesive skin patch in which pickup pieces are not made to return to an original place when detachment liners are detached from a division cut-off line and folded, in the adhesive skin patch having the detachment liners.
SOLUTION: The adhesive skin patch 1 includes: the division cut-off line 5; and bending lines 7 arranged at the side parts of the division cut-off line. The bending lines 7 includes: cuts 8; and joint parts 9 formed with interval close to the division cut-off line 5 from the cuts 8. Notch lines 11 are provided, which connect the cuts 8 to the joint parts 9 so as to demarcate and form tongue pieces 10 with the cuts 8 made one sides. When the liners 4 are detached from the division cut line 5 and bent, the distal end parts of the tongue pieces 10 demarcated and formed by the cuts 8 and the notch lines 11 are projected toward the adhesive skin patch layer 3 and brought into contact with the adhesive skin patch layer 3.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种粘合性皮肤贴片，其中当拆卸衬垫从分割切割线分离并折叠时，拾取片不会返回到原始位置，在具有分离的粘合性皮肤贴片中衬垫。胶粘剂皮肤贴片1包括：切割线5; 以及布置在分割截止线的侧部的弯曲线7。弯曲线7包括：切口8; 以及从切口8形成为具有接近分割切割线5的间隔的接合部分9.设置切口8将切口8连接到接合部分9上以切割并形成具有切口8的舌片10的切口线11 一方面。当内衬4与分割线5分离并弯曲时，由切口8和切口线11划定并形成的舌片10的远端部朝向粘合性皮肤贴片层3突出并与粘性皮肤贴片层3.版权所有（C）2009，JPO＆INPIT

5. 发明专利

JP2005281202A Substrate for percutaneous absorption type plaster adhesive and percutaneous absorption type adhesive plaster 审中-公开
标题翻译：用于经皮吸收型塑料粘合剂和经皮吸收型粘合剂的基材
公开(公告)号：JP2005281202A
公开(公告)日：2005-10-13
申请号：JP2004098055
申请日：2004-03-30
申请人： Nichiban Co Ltd , ニチバン株式会社
发明人： KAWAHARA YASUSHIGE , OYAMA KUNIHIRO
IPC分类号： A61K9/70
摘要： PROBLEM TO BE SOLVED: To provide a percutaneous absorption type adhesive plaster which is flexible, excels in a feeling of application, has good handling properties, and can stably obtain a high dermal permeability, and a substrate for the adhesive plaster.
SOLUTION: The substrate for the percutaneous absorption type adhesive plaster is composed of a laminated sheet obtained by laminating a polypropylene nonwoven fabric having a weight basis of 3.0-10.0 g/m
2 on one side of a polyester film having a thickness of 1.5-12 μm. The percutaneous absorption type adhesive plaster has a layer structure such that a pressure sensitive adhesive layer containing a drug is arranged on any one side of the substrate.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：解决问题：为了提供柔软的经皮吸收型粘合剂，具有优异的使用感，具有良好的操作性能，并且可以稳定地获得高的皮肤渗透性，以及用于胶粘剂的基材。解决方案：用于经皮吸收型粘合剂的基材由层压片材组成，该层压片材通过将重量基准为3.0-10.0g / m 2的SP的聚丙烯无纺布层叠在厚度为1.5-12μm的聚酯膜。经皮吸收型粘合剂具有层状结构，使得含有药物的压敏粘合剂层配置在基材的任一侧。版权所有（C）2006，JPO＆NCIPI

6. 发明专利

JP2004229830A Rolled medical adhesive tape 有权
公开(公告)号：JP2004229830A
公开(公告)日：2004-08-19
申请号：JP2003020949
申请日：2003-01-29
申请人： Nichiban Co Ltd , ニチバン株式会社
发明人： OYAMA KUNIHIRO , FUJISAWA HIROMITSU , TAKAGI YASUYO
IPC分类号： A61F13/02 , C09J7/02 , C09J107/00 , C09J153/02
摘要： PROBLEM TO BE SOLVED: To provide a rolled medical adhesive tape having superior hand-cutting property, having superior rewinding property even if being formed into a direct winding roll and being overlappedly stuck on the tape in the medical adhesive tape using a nonwoven cloth with permeability and elasticity as a support. SOLUTION: This rolled medical adhesive tape wound into a roll is formed with an adhesive layer on one face of a support. The support is formed of the nonwoven cloth having an orientation in the width direction of the adhesive tape formed of synthetic resin filaments, the rear face opposite to the adhesive layer of the support is formed with recesses/projections by embossing, the embossed surface of the support rear face is applied with release agent and the adhesive tape is formed into the roll by winding the adhesive layer with its in contact with the support rear face. COPYRIGHT: (C)2004,JPO&NCIPI

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