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1. 发明专利

JPS6017206B2 失效
公开(公告)号：JPS6017206B2
公开(公告)日：1985-05-01
申请号：JP3241277
申请日：1977-03-24
申请人： MAEDA HIROSHI , ISHIDA NAKAO
发明人： MAEDA HIROSHI , KANAMARU RYUNOSUKE , ISHIDA NAKAO
IPC分类号： C08F8/00 , A61K38/00 , A61P35/00 , C07K1/113 , C07K14/36 , C07K14/37 , C07K14/41 , C07K17/08 , C08F8/30 , C08F8/32

2. 发明专利

JPS53117095A NEOCARCINOSTACHIN DERIVATIVE AND PRODUCING PROCESS THEREOF 失效
公开(公告)号：JPS53117095A
公开(公告)日：1978-10-13
申请号：JP3241277
申请日：1977-03-24
申请人： MAEDA HIROSHI , ISHIDA NAKAO
发明人： MAEDA HIROSHI , KANAMARU RIYUUNOSUKE , ISHIDA NAKAO
IPC分类号： C08F8/00 , A61K38/00 , A61P35/00 , C07K1/113 , C07K14/36 , C07K14/37 , C07K14/41 , C07K17/08 , C08F8/30 , C08F8/32

3. 发明专利

JPS60100522A CARCINOSTATIC AGENT 失效
公开(公告)号：JPS60100522A
公开(公告)日：1985-06-04
申请号：JP19367784
申请日：1984-09-14
申请人： MAEDA HIROSHI , ISHIDA NAKAO
发明人： MAEDA HIROSHI , KANAMARU RIYUUNOSUKE , ISHIDA NAKAO
IPC分类号： A61K38/00 , A61P35/00
摘要： PURPOSE:A carcinostatic agent containing a neocarzinostatin derivative having low toxicity, being accumulated specifically in lymphocyte. CONSTITUTION:A carcinostatic agent containing a compound shown by the formula (ring N is neocarzinostatin residue; R1+R2 is residue of styrene-maleic acid copolymer having 2,500-80,000mol.wt) as an active ingredient. Administration in tissue of affected part such as primary site of cancer, site from which cancer is extracted after operation, etc., intracutaneous, hypodermic, intramuscular, intravenous, and oral medication, etc., application to the affected part, and administration of external use such as suppository may be used as the administration. A dose is 0.1-10mg/kg/time/day, preferably once-twice per week or daily administration. The compound shown by the formula as the active ingredient is obtained by reacting neocarzinostatin with a styrene-maleic acid copolymer containing at least one maleic anhydride residue in the molecule in neutrality or in weak basicity at 0-40 deg.C.

4. 发明专利

JP2006350501A MICROCOMPUTER DRIVING BOARD 审中-公开
公开(公告)号：JP2006350501A
公开(公告)日：2006-12-28
申请号：JP2005173362
申请日：2005-06-14
申请人： MAEDA HIROSHI
发明人： MAEDA HIROSHI
IPC分类号： G06F11/00 , G06F15/78
摘要： PROBLEM TO BE SOLVED: To enable a user to efficiently develop the program of a microcomputer. SOLUTION: In first embodiment, a dip switch for switching a writing execution mode is arranged so as to be physically independent of a disk switch group. Thus, it is possible for a user to easily understand the arrangement of the writing execution mode changeover switch, and to improve operability. Also, in the modification of the first embodiment, a writing execution mode can be set by using a toggle switch in addition to the dip switch, and the switching of the switch can be much more easily executed. In second embodiment, the program writing mode and a program execution mode can be switched by a remote operation by using a serial interface. Thus, it is possible to prevent the abrasion of the dip switch due to the switching of the writing execution mode. Also, it is possible for the user to switch the writing execution mode by the remote operation. COPYRIGHT: (C)2007,JPO&INPIT

5. 发明专利

JP2001247475A NEW CYSTEINE PROTEASE INHIBITOR 失效
公开(公告)号：JP2001247475A
公开(公告)日：2001-09-11
申请号：JP2000057674
申请日：2000-03-02
申请人： CHEMO SERO THERAPEUT RES INST , MAEDA HIROSHI
发明人： MAEDA HIROSHI , AKAIKE TAKAAKI , MIYAMOTO YOICHI , FUJII SHIGEMOTO , IKEBE MUNESATO , YOSHITAKE ATSUSHI , MUHAMMAD SAMIURU ALAM , OKAMOTO TATSUYA , INOUE KATSUHISA , HAMAMOTO TAKAYOSHI
IPC分类号： C12N9/99 , A61K38/55 , A61P1/16 , A61P7/00 , A61P9/10 , A61P11/00 , A61P29/00 , A61P43/00 , C07K14/81
摘要： PROBLEM TO BE SOLVED: To obtain a new cysteine protease inhibitor having a strong inhibiting action. SOLUTION: A cysteine protease inhibitor consisting essentially of S- nitrosated α1 protease inhibitor obtained by nitrosating the cysteine residue of α1 protease inhibitor. The cysteine protease inhibitor is useful as a therapeutic medicine suitable for diseases to which the increase or decrease of cysteine protease deeply relates, such as acquired pneumonia (pulmonary emphysema), fulminant hepatitis, cardiac infarction, ARDS (adult acute respiratory distress syndrome), various inflammatory diseases, or shock-like syndromes caused with bacterial toxin.

6. 发明专利

JPH1171023A TRANSFERRING-SORTING CONVEYER 失效
公开(公告)号：JPH1171023A
公开(公告)日：1999-03-16
申请号：JP27187297
申请日：1997-08-28
申请人： MAEDA HIROSHI
发明人： MAEDA HIROSHI , HARAGUCHI KAZUO
IPC分类号： B65G47/68
摘要： PROBLEM TO BE SOLVED: To prevent a pin of a slide piece for a sorting conveyer from causing trouble at a sorting point, by scooping up the pin to the transversely pre-moved slide piece by a sorting guide rail and guiding it in the sorting direction. SOLUTION: An activating device 7 provided on the upstream side of a sorting point 6 previously pushes a slide piece 3B for sorting to a sorting side, and moves a pin 301B to a sorting passage 602 outside of a straight passage. Then, the pin is guided in the sorting direction by a tip 501 of a guide rail 5 at a sorting point 6 such that the pin is scooped. The pin 301B of the slide piece 3B which is moved from the straight passage 601 to the sorting passage 602 by the activating device 7 on the upstream side of the sorting point 6 abuts to the guide rail 5 and transversely moves toward the sorting direction to a termination 502. Articles are pressed in the side by the transversely moving slide piece 3B, and due-out-sorted to a branch conveyer Y.

7. 发明专利

JPH1160499A ANTITUMOR AGENT 失效
公开(公告)号：JPH1160499A
公开(公告)日：1999-03-02
申请号：JP24023597
申请日：1997-08-22
申请人： MAEDA HIROSHI
发明人： SAWA TOMOHIRO , AKAIKE TAKAAKI , MAEDA HIROSHI
IPC分类号： A61K38/44 , A61K45/06 , A61K47/48 , A61P35/00 , C12N11/08
摘要： PROBLEM TO BE SOLVED: To obtain an antitumor agent having high antitumor activity, while extremely low in side effects against normal tissues/organs other than tumor in question. SOLUTION: This antitumor agent has a unique action mechanism making use of the cancer cell-killing action by active oxygen molecular species which is formed by reaction of hypoxanthine (HX) as the substrate of xanthine oxidase (XO) with polyethylene glycol-xanthine oxidase (PEG-XO) which is formed by chemically modifying the lysine residue of XO as active oxygen-forming enzyme with activated PEG to obviate the non-specific adsorption of XO to the vascular endothelia and raise the cumulativeness on tumor site(s).

8. 发明专利

JP2556865B2 失效
公开(公告)号：JP2556865B2
公开(公告)日：1996-11-27
申请号：JP18856087
申请日：1987-07-28
申请人： YAMANOCHI SEIYAKU KK , MAEDA HIROSHI , KURARE KK , KAYAKU KK
发明人： MAEDA HIROSHI , SUZUKI FUJIO , OKAKI ICHIRO , TANAKA SHOHEI
IPC分类号： A61K38/00 , A61K9/10 , A61K9/107 , A61K31/785 , A61K47/00 , A61K47/10 , A61K47/14 , A61K47/48 , A61P35/00 , G03C1/06 , G03C1/485

9. 发明专利

JPH0830080B2 失效
公开(公告)号：JPH0830080B2
公开(公告)日：1996-03-27
申请号：JP4126488
申请日：1988-02-24
申请人： MAEDA HIROSHI , HOORA KASEI KOGYO KK
发明人： MAEDA HIROSHI , ODA TATSUYA , MIKI TOYOHIKO , KOIDE YOSHIO , ITO AKIRA
IPC分类号： A61K38/00 , A61P35/00 , C07K1/113 , C07K14/00 , C07K14/195 , C07K14/36 , C07K14/41 , C07K17/08 , C08F8/32

10. 发明专利

JPH07121869B2 失效
公开(公告)号：JPH07121869B2
公开(公告)日：1995-12-25
申请号：JP25385393
申请日：1993-10-12
申请人： MAEDA HIROSHI , FUJI SEIYU KK
发明人： MAEDA HIROSHI , MATSUMURA YASUHIRO , TAKAMATSU SEIJI , SHIMODA TADAHISA
IPC分类号： A61K36/48 , A61K38/55 , A61P3/00 , A61P29/00 , A61P43/00 , A61K35/78

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