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    • 1. 发明专利
    • Dentifrice composition
    • DENTIFRICE组成
    • JP2003292426A
    • 2003-10-15
    • JP2002383532
    • 2002-12-25
    • Lion Corpライオン株式会社
    • AKAHA YASUHIROFUKAZAWA SATORUIDE YASUHIKOYAMAMOTO TAKASHI
    • A61K8/00A61K8/33A61K8/39A61Q11/00A61K7/16
    • PROBLEM TO BE SOLVED: To provide a dentifrice composition having sufficient antimicrobial activities even after a long-term preservation because of little adsorption of a nonionic antimicrobial agent on a polyethylene container, a polypropylene container or the like, and enabling a dentifrice composition to be set with high degree of freedom.
      SOLUTION: The dentifrice composition contains a slightly water-soluble nonionic antimicrobial agent and a polyoxyethylene alkyl ether having a 14-18C alkyl group, and packed in a container having the most inner layer comprising a plastic having high compatibility with the slightly water-soluble nonionic antimicrobial agent.
      COPYRIGHT: (C)2004,JPO
    • 待解决的问题:为了提供即使在长期保存后也具有足够的抗微生物活性的洁牙剂组合物,因为非离子型抗微生物剂几乎不吸附在聚乙烯容器,聚丙烯容器等上,并且使牙粉组合物 被设定在高度的自由度。 解决方案:洁齿剂组合物含有微溶于水的非离子型抗微生物剂和具有14-18C烷基的聚氧乙烯烷基醚,并且包装在具有最内层的容器中,该容器具有与微水相容性高的塑料 可溶性非离子型抗菌剂。 版权所有(C)2004,JPO
    • 5. 发明专利
    • Dentifrice composition
    • DENTIFRICE组成
    • JP2005343839A
    • 2005-12-15
    • JP2004166729
    • 2004-06-04
    • Lion Corpライオン株式会社
    • YAMAMOTO KOJIFUKAZAWA SATORUHIRATSUKA SUSUMU
    • A61K8/21A61K8/24A61K8/26A61K8/34A61Q11/00A61K7/18
    • PROBLEM TO BE SOLVED: To obtain a dentifrice composition having proper tooth-polishing property injuring no tooth, sufficiently exerting effectiveness derived from a fluorine compound and xylitol and having excellent smoothing effect on the tooth surface.
      SOLUTION: This dentifrice composition comprises (A) calcium hydrogenphosphate, (B) aluminum oxide of ≤90% alfatized degree, (C) a fluorine compound and (D) xylitol, wherein the mass ratio of (A) ingredient to (B) ingredient is from 100:1 to 100:20 and the total compounded amount of the (A) ingredient and the (B) ingredient is 30-60 mass%.
      COPYRIGHT: (C)2006,JPO&NCIPI
    • 要解决的问题:为了获得具有适当的牙齿抛光性能的牙粉组合物,没有损伤牙齿,充分发挥来自氟化合物和木糖醇的功效,并且对牙齿表面具有优异的平滑效果。 解决方案:该洁齿剂组合物包含(A)磷酸氢钙,(B)≤90%脱脂度的氧化铝,(C)氟化合物和(D)木糖醇,其中(A)成分与(A) B)成分为100:1〜100:20,(A)成分和(B)成分的总配合量为30〜60质量%。 版权所有(C)2006,JPO&NCIPI
    • 6. 发明专利
    • Dentifrice composition
    • DENTIFRICE组成
    • JP2007169234A
    • 2007-07-05
    • JP2005371632
    • 2005-12-26
    • Lion Corpライオン株式会社
    • FUKAZAWA SATORUHIRATSUKA SUSUMU
    • A61K8/49A61K8/19A61K8/23A61K8/26A61K8/44A61Q11/00
    • PROBLEM TO BE SOLVED: To obtain a dentifrice composition that has reduced polishing force derived from calcium carbonate and low polishing force in spite of using calcium carbonate as an abrasive, does not cause a liquid separation, has improved foaming, excellent formulation stability and sense of use.
      SOLUTION: The dentifrice composition comprises (A) calcium carbonate, (B) aluminum hydroxide, (C) sodium sulfate, (D) sodium lauryl sulfate and (E) at least one amphoteric surfactant selected from 2-alkyl-N-carobxymethyl-N-hydroxyethylimidazolinium betaine, alkyldimethylaminoacetic acid betaine and fatty acid amidopropyl betaine in the mixing ratio of component (E)/(D) by mass ratio of 0.25-1.0.
      COPYRIGHT: (C)2007,JPO&INPIT
    • 待解决的问题:为了获得尽管使用碳酸钙作为研磨剂,具有减少由碳酸钙衍生的抛光力和低抛光力的洁齿剂组合物,不会引起液体分离,具有改善的起泡性,优异的配制稳定性 和使用感。 (A)碳酸钙,(B)氢氧化铝,(C)硫酸钠,(D)十二烷基硫酸钠和(E)至少一种两性表面活性剂,其选自2-烷基-N- 按照质量比为0.25-1.0的组分(E)/(D)的混合比例,焦磷酸甲基-N-羟乙基咪唑鎓甜菜碱,烷基二甲基氨基乙酸甜菜碱和脂肪酸酰胺丙基甜菜碱。 版权所有(C)2007,JPO&INPIT
    • 7. 发明专利
    • Dentifrice composition
    • DENTIFRICE组成
    • JP2007045743A
    • 2007-02-22
    • JP2005231889
    • 2005-08-10
    • Lion Corpライオン株式会社
    • FUKAZAWA SATORUHIRATSUKA SUSUMUYAMAMOTO TAKASHI
    • A61K8/00A61Q11/00
    • PROBLEM TO BE SOLVED: To provide a dentifrice composition having promoted trans-mucous membrane absorptivity of acetyleugenol having excellent effects for blocking alveolar bone absorption, providing no irritation to the mucous membrane, hardly causing liquid separation of the dentifrice, having good foamability and effective for prevention and treatment of periodontal disease. SOLUTION: The dentifrice composition comprises (A) 0.1-3.0 mass% acetyleugenol, (B) 0.5-3.0 mass% linear water-soluble polyphosphoric acid salt represented by general formula M n+2 P n O 3n+1 (wherein, M is Na or K; and n is 2 or 3), (C) 0.5-10 mass% nonionic surfactant, regulated so that the mass ratio (B)/(A) of the components (B) to (A) may be 0.2-5.0. The dentifrice composition further comprises 0.5-10 mass% ampholytic surfactant besides them. COPYRIGHT: (C)2007,JPO&INPIT
    • 要解决的问题:提供具有促进阻断牙槽骨吸收效果优异的乙酰丁香酚的透粘膜吸收性的洁牙剂组合物,不会对粘膜造成刺激,几乎不引起洁齿剂的液体分离,具有良好的发泡性 有效预防和治疗牙周病。 < P>解决方案:洁牙剂组合物包含(A)0.1-3.0质量%的乙酰丁烯醇,(B)0.5-3.0质量%的由通式M表示的直链水溶性多磷酸盐 (其中,M为Na或K; n为2或3),(C)为0.5-10质量%的非离子表面活性剂,调节为 组分(B)至(A)的质量比(B)/(A)可以为0.2-5.0。 除了它们之外,洁齿剂组合物还包含0.5-10质量%的两性表面活性剂。 版权所有(C)2007,JPO&INPIT