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    • 4. 发明专利
    • METHOD AND APPARATUS FOR REACTING MICROORGANISM
    • JPS57166985A
    • 1982-10-14
    • JP5081281
    • 1981-04-03
    • KAWASAKI HEAVY IND LTDRIKAGAKU KENKYUSHO
    • TAKAHATA TOSHIOITOU HAYAMIZUNAGAI KOUZOUENDOU ISAOINOUE ICHIROU
    • C12M1/40C12P1/00
    • PURPOSE:To carry out the biochemical reaction, in high efficiency, by forming a plurality of spaces with porous material layers, feeding a liquid containing microorganisms or enzymes to some of the spaces and feeding raw material liquid to the other spaces, and passing the liquid through the porous layers reciprocally by the pressure difference. CONSTITUTION:The reactors 1,2 are divided into the inner space 4 and the outer space 5 by the porous material layer 3 having micropores which inhibit the passage of microorganisms and enzymes and obtained by sintering the fine particles of metals, ceramics, etc. Microorganisms and its medium, immobilized enzyme and a buffer solution, etc. are circulted in the inner space 4, and the raw material liquid is circulated in the outer space 5. The circulation system is furnished with electromagnetic valves, pumps, etc. to enable the reversion of the flow direction of the liquid. Pressure difference is applied between the inner space and the outer space in a manner to permeate the raw material liquid from the outer space to the inner space 4 in the reaction unit 1, and from the inner space to the outer space 5 through the layer 3 in the unit 2. The product is taken out through the pipe 15 and separated. The clogging of the layer can be removed by reverting flow direction of the liquid.