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    • 2. 发明专利
    • Method for detecting biological sample
    • 检测生物样品的方法
    • JP2009047705A
    • 2009-03-05
    • JP2008263867
    • 2008-10-10
    • Hayashibara Biochem Lab Inc株式会社林原生物化学研究所
    • YAMAMURA MASAHIROTANIMOTO TADAOKURIMOTO MASASHI
    • G01N33/53
    • PROBLEM TO BE SOLVED: To provide method for detecting any biological sample extracted from a test subject which comprises partial amino acid sequence shown in sequence numbers 1, 2, 3 and 4 of sequence listing, and in which the protein level inducing production of interferon-gamma in immunocompetent cell is higher than that of the biological sample extracted from a normal subject.
      SOLUTION: Monoclonal antibody specific to the protein having particular amino acid sequence is placed in contact with the biological sample extracted from a test subject to design this method for detecting any biological sample in which the protein level inducing production of interferon-gamma in immunocompetent cell is higher than that of the biological sample extracted from a normal subject, based on antigen-antibody reaction between the above monoclonal antibody and the biological sample, solving related problems.
      COPYRIGHT: (C)2009,JPO&INPIT
    • 待解决的问题:提供检测从测试对象提取的任何生物样品的方法,其包括序列表中序号1,2,3和4所示的部分氨基酸序列,其中蛋白质水平诱导产生 的免疫活性细胞中的干扰素γ高于从正常受试者提取的生物样品。 解决方案:将具有特定氨基酸序列的蛋白质特异性的单克隆抗体与从测试对象提取的生物样品接触,设计该方法,用于检测其中产生干扰素-γ的蛋白质水平的任何生物样品 基于上述单克隆抗体与生物样品之间的抗原 - 抗体反应,免疫活性细胞高于从正常受试者提取的生物样品的免疫活性细胞,解决相关问题。 版权所有(C)2009,JPO&INPIT