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1. 发明专利

JPH04207191A METHOD AND DEVICE FOR EXTRACTING INTRACELLULAR INGREDIENT 失效
公开(公告)号：JPH04207191A
公开(公告)日：1992-07-29
申请号：JP34073190
申请日：1990-11-30
申请人： HITACHI PLANT ENG & CONSTR CO , MEIJI SEIKA KAISHA , TOTO LTD
发明人： FUKUSHIMA YUKIO , KON MASAHIRO , UOTANI KAZUMICHI , YAMANO SHIGERU
IPC分类号： C12M1/00 , B01D33/21 , C12M1/12 , C12N1/00
摘要： PURPOSE:To efficiently obtain the objective substance in a high yield and at a low cost by filtering off only the liquid from a culture solution in an extraction device, washing the substance remaining in the device with pure water, and subsequently charging a solvent in the device to extract the ingredient from the cells. CONSTITUTION:A culture solution is fed into an extraction device, and only the liquid in the culture solution is filtered off. The filtrate is taken out from the device. Pure water is charged in the extraction device, and substances remaining in the extraction device are discharged from the device together with the water. A solvent is charged in the extraction device, and the objective substance contained in cells is dissolved in the solvent. Finally, the solution is filtered and taken out from the extraction device, and the objective substance is separated from the solution.

2. 发明专利

JPH04126068A METHOD FOR CULTURING CELL AND APPARATUS THEREFOR 失效
公开(公告)号：JPH04126068A
公开(公告)日：1992-04-27
申请号：JP24663890
申请日：1990-09-17
申请人： HITACHI PLANT ENG & CONSTR CO , TOTO LTD
发明人： KON MASAHIRO , FUKUSHIMA YUKIO , SUZUKI SHIGEMI , YAMANO SHIGERU , MAEHASHI NOBUYUKI
IPC分类号： C12M3/00 , C12M3/06 , C12N5/07 , C12N5/071
摘要： PURPOSE:To culture a large amount of cells at a high density by feeding a fresh culture solution through a through hole formed in a supporting shaft into a hermetically closed container, supplying nutriments and oxygen to cells stuck to perforated plates of a filter unit communicating with the through hole and simultaneously removing waste products. CONSTITUTION:Steam is fed from a boiler 40 through an inflow port 22 into a hermetically closed container 12 to carry out empty sterilization. Warm water is then circulated from warm water feed port 52 to a jacket 25 of the container 1 to keep the container 12 at a prescribed temperature. A compressor 30 and a vacuum pump 32 are then operated to feed cells from a seed cell vessel 34 into the container 12 and a culture solution is simultaneously fed from a storage tank 39 into the container 12. A buffer solution is subsequently fed from a storage tank 36 through the inflow port 22 into the container 12. The culture solution is then taken out through perforated plates 20 and a through hole 16 in a rotating shaft 14 to stick the cells to the surfaces of the perforated plates 20. A fresh culture solution containing nutriments and oxygen is subsequently fed into the container 12 to supply the nutriments and oxygen to the cells and the culture solution containing waste products is simultaneously taken out through the perforated plates 20 and the through hole 16.

3. 发明专利

JPH05103955A MEMBRANE TREATMENT 失效
公开(公告)号：JPH05103955A
公开(公告)日：1993-04-27
申请号：JP29795791
申请日：1991-10-18
申请人： TOTO LTD
发明人： YAMANO SHIGERU , OSHIMA TAKAFUMI , KANEKUNI NOBUHIKO , TABATA KENJI
IPC分类号： B01D61/14 , B01D61/58
摘要： PURPOSE:To drastically improve the yield of a product by almost using up an untreated original liquid in a circulation type membrane treatment. CONSTITUTION:If the original liquid in the original liquid tank 1 used up or becomes below a prescribed quantity, the 1st separation by a 1st circulation type membrane treatment device is finished and the 2nd separation by a 2nd circulation type membrane treatment device is prepared for use. As the preparation, in the state that the valves V1, V2, V7 and V10 are opened and one more valve is closed, hot water from a hot water tank 2 is fed to the 1st circulation type membrane device 11 to supply the original liquid held respectively in the 1st order side of membrane modules M1, M2, M3 and M4 to a cushion tank 22. As the next preparation, in the state that the valves V1, V8, V9 and V10 are opened and one more valve is closed, the hot water from the hot water tank 2 is fed only to a return pipe line 14 to feed the residual original liquid in the pipe line 14 to the cushion tank 22.

4. 发明专利

JPH04243529A 失效
公开(公告)号：JPH04243529A
公开(公告)日：1992-08-31
申请号：JP2399191
申请日：1991-01-24
申请人： TOTO LTD
发明人： YAMANO SHIGERU , NOGAKI HISASHI , MAEHASHI NOBUYUKI
IPC分类号： B01D65/02
摘要： PURPOSE:To wash a filter membrane in order to recover the filtering capacity thereof. CONSTITUTION:A supply solution is supplied to the primary side of a membrane 5 under pressure and a concentrated solution is circulated through a pipe joint 9 and the transmitted solution issued to the secondary side of the membrane 5 is recovered through a transmitted solution flow passage 11. The flow passage 11 of the transmitted solution on the secondary side is cyclically opened and closed by an opening and closing valve 12 while the treated solution on the primary side is circulated during operation. When the flow passage of the transmitted solution on the secondary side is opened and closed at a predetermined cycle while the treated solution on the primary side of the membrane is circulated, the treated solution flows along the membrane during a period when the flow passage of the transmitted solution on the secondary side is closed without being transmitted through the membrane and, as a result, the cake layer formed on the surface of the membrane becomes thin and filtering capacity is recovered.

5. 发明专利

JPS63242340A CERAMICS SEPARATION MEMBRANE FOR ENZYME IMMOBILIZATION 失效
公开(公告)号：JPS63242340A
公开(公告)日：1988-10-07
申请号：JP7934387
申请日：1987-03-30
申请人： TOTO LTD
发明人： KOGA NAOKI , MAEHASHI NOBUYUKI , YAMANO SHIGERU
IPC分类号： C12N11/14 , B01J20/02 , B01J20/28
摘要： PURPOSE:To increase the amount of enzyme to be immobilized, by forming a glass layer to the surfaces of ceramics aggregate particles and bonding the ceramics aggregate particles to each other through said glass layer to constitute a ceramics separation membrane. CONSTITUTION:A glass layer 3 bonding ceramics aggregate particles 2 to each other is formed to the surfaces of said particles 2 to constitute a ceramics separation membrane 1 having a porous structure wherein pores 4 allowing the inside and outside to communicate with each other are formed between each of the particles 2. As the material quality of the ceramics aggregate particles 2, alumina, silica or mullite is used and the particle size thereof is set to about 1-100mum and the size of the pores 4 formed between the particles 2 is set to about 0.1-50mum. As the glass layer 3 covering the surfaces of the particles 2, it is pref. to use borosilicate glass rich in SiO2 and the wt. ratio thereof to the ceramics aggregate particles is pref. 5-20%.

6. 发明专利

JPH04132796A PRODUCTION OF VEGETABLE OIL 失效
公开(公告)号：JPH04132796A
公开(公告)日：1992-05-07
申请号：JP25413790
申请日：1990-09-26
申请人： MITSUBISHI KAKOKI KK , TOTO LTD
发明人： SUZUKI SHIGEMI , MAEHASHI NOBUYUKI , YAMANO SHIGERU , NOGAKI HISASHI , TAMAKI AKIO , NOGUCHI AKITERU
IPC分类号： C11B3/16 , B01D61/14 , B01D71/02 , C11B3/00
摘要： PURPOSE:To economically and rapidly obtain high-quality vegetable oils with hardly any contamination of phospholipids, etc., by permeating miscellas prepared from plant seeds through an ultrafiltration membrane at a specific temperature and then removing impurities in the miscellas. CONSTITUTION:Plant seeds such as soybean, rapeseed, safflower, corn, sunflower or rice bran are extracted with an organic solvent preferably composed of n-hexane to provide miscellas, which are then heated at 50-120 deg.C (preferably 50-90 deg.C). In this state, the miscellas are subsequently permeated through an ultrafiltration membrane composed of an inorganic micromembrane having 30-100Angstrom pore diameter. Impurities such as phospholipids contained in the miscellas are removed to afford the objective vegetable oil.

7. 发明专利

JPH03155776A PREPARATION OF PURE 'SAKE' 失效
公开(公告)号：JPH03155776A
公开(公告)日：1991-07-03
申请号：JP29635689
申请日：1989-11-15
申请人： TOKYO ELECTRIC POWER CO , TOTO LTD , MITSUBISHI KAKOKI KK
发明人： KURODA SHOICHI , SHIBATA SOICHIRO , SUZUKI SHIGEMI , YAMANO SHIGERU , MATSUOKA KEIICHIRO , FUKUCHI TADAJIROU
IPC分类号： C12G3/02 , B01D61/14 , B01D71/02
摘要： PURPOSE:To prepare pure SAKE (Japanese rice wine) having freshness and natural feeling by removing residues such as enzymes from raw SAKE using an ultrafiltration membrane produced by forming a zirconia thin film having a pore size falling within a prescribed range on the surface of a porous ceramic substrate. CONSTITUTION:A fermented raw SAKE is passed through an ultrafiltration membrane produced by forming a zirconia(ZrO2) thin film having a pore diameter of 130-220Angstrom on the surface of a porous ceramic substrate. The residues such as enzymes ca be removed from the raw SAKE by this process to obtain the objective pure SAKE.

8. 发明专利

JPH06339681A ACTIVE CARBON REGENERATION-TYPE WATER PURIFIER 失效
公开(公告)号：JPH06339681A
公开(公告)日：1994-12-13
申请号：JP15303093
申请日：1993-05-31
申请人： TOTO LTD
发明人： YAMANO SHIGERU , ENOMOTO KAZUYUKI , WATANABE KAZUYUKI , ANDO SHIGERU
IPC分类号： B01D63/02 , C02F1/28 , C02F1/44
摘要： PURPOSE:To use a hollow fiber membrane filter combinedly in an active carbon regeneration-type water-purifier by preventing deterioration of the hollow fiber membrane filter due to heat and occurrence of vapor lock due to steam. CONSTITUTION:In an active carbon regeneration-type water-purifier, an active carbon cartridge 84, and a heater 158 for heating and regenerating the active carbon are provided. Further, a hollow fiber membrane filter 52 for beforehand removing particle components in the tap water by filtration is disposed upstream of the active carbon cartridge, the hollow fiber membrane filter and the active carbon cartridge are connected to each other through water-tight tap water passages 74 and 78.

9. 发明专利

JPH06339680A ACTIVE CARBON REGENERATION-TYPE WATER PURIFIER 失效
公开(公告)号：JPH06339680A
公开(公告)日：1994-12-13
申请号：JP15302993
申请日：1993-05-31
申请人： TOTO LTD
发明人： YAMANO SHIGERU , OSHIMA TAKAFUMI , TOKIDA MASAHIRO , KASUKAWA ATSUHIKO
IPC分类号： B01J20/34 , C02F1/28 , C02F1/44
摘要： PURPOSE:To provide an active carbon regeneration-type water purifier which is capable of regenerating and sterilizing active carbon by simply boiling by energizing a heater and is suited for automatic regeneration. CONSTITUTION:This active carbon regeneration-type water purifier regenerates active carbon by allowing tap water to come in contact with active carbon stored in a container to purify tap water, then regenerates the active carbon by heating the container at any time using a heating means to boil the water which is resident in the container, and at the same time, sterilizes the water by boiling. The outlet 102 of the container is connected to a purified water discharge passage 130 and a heated water/vapor discharge path 152 through an automatic switching valve 128. In addition, the outlet of the container is connected to the purified water discharge passage during supply of purified water so that the purified water is discharged from the purified water discharge passage. Further, when the heating means is operated, the outlet of the container is automatically switched to the discharge passage to allow the discharge of heated water or steam from the discharge passage.

10. 发明专利

JPH0265783A IMMOBILIZATION OF ENZYME 失效
公开(公告)号：JPH0265783A
公开(公告)日：1990-03-06
申请号：JP21465188
申请日：1988-08-29
申请人： NAT FOOD RES , TOTO LTD
发明人： WATANABE ATSUO , NAKAJIMA MITSUTOSHI , OTANI TOSHIRO , NABEYA HIROSHI , YAMANO SHIGERU , MAEHASHI NOBUYUKI , NOGAKI HISASHI
IPC分类号： C12N11/14
摘要： PURPOSE:To obtain immobilized enzyme containing large amount of immobilized enzyme and having high safety for food industry, etc., by refluxing solution of Zr-based crosslinking agent through porous immobilized carrier, physically bonding said crosslinking agent to the surface of the pore, refluxing enzyme solution and bonding enzyme to the crosslinking agent. CONSTITUTION:An aqueous solution of zirconium-based crosslinking agent (e.g., zirconyl carbonate ammonium) filled in a tank 12 is refluxed through porous immobilized carrier 1 (e.g., ceramics) by pump 11 and the zirconium-based crosslinking agent 3 is physically bonded to the surface of pores of the immobilized carrier in laminar state, then the immobilized carrier 1 is connected to a vessel 16 filled with enzyme solution, thus the enzyme solution is refluxed through the immobilized carrier 1 by pressure of a bomb 15 and the enzyme 4 is chemically bonded to the zirconium-based crosslinking agent 3 to afford the aimed immobilized enzyme.

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