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    • 1. 发明专利
    • Analyte recovery device and analyte recovery method
    • 分析恢复装置和分析恢复方法
    • JP2007003490A
    • 2007-01-11
    • JP2005187202
    • 2005-06-27
    • Fujifilm Holdings Corp富士フイルムホールディングス株式会社
    • FUJIKURA TATSUO
    • G01N33/566G01N21/27G01N33/53G01N33/543
    • G01N35/08G01N21/253G01N21/553G01N21/554G01N2035/00158
    • PROBLEM TO BE SOLVED: To provide an analyte recovery device and an analyte recovery method for bonding efficiently an analyte to a ligand in a prescribed amount of analyte solution and recovering the bonded analyte.
      SOLUTION: It is determined whether bonding between the ligand D and the analyte A is in the saturated state or not based on bonding state data acquired by measuring processing. When determined that the bonding is not in the saturated state, the analyte solution YA recovered by a pipette chip CPB is injected from a discharge port 45B into a liquid passage 45, and the analyte solution YA discharged from the supply port 34A side is recovered by the pipette chip CPA. Hereby, the analyte solution YA in the liquid passage 45 is replaced with the analyte solution YA sucked into the pipette chip CPB. The analyte solution YA is stirred by the replacement operation, and concentration unevenness of the analyte A in the liquid passage 45 is removed, to thereby accelerate bonding to the ligand D.
      COPYRIGHT: (C)2007,JPO&INPIT
    • 要解决的问题:提供分析物回收装置和分析物回收方法,用于将分析物有效地结合到规定量的分析物溶液中的配体上并回收结合的分析物。 解决方案:基于通过测量处理获得的结合状态数据,确定配体D和分析物A之间的结合是否处于饱和状态。 当确定接合不处于饱和状态时,通过移液管芯片CPB回收的分析物溶液YA从排出口45B注入到液体通道45中,从供给口34A侧排出的分析物溶液YA通过 移液器芯片CPA。 由此,液体通道45中的分析物溶液YA被吸入移液管芯片CPB中的分析物溶液YA代替。 通过置换操作搅拌分析物溶液YA,除去液体通道45中的分析物A的浓度不均匀,从而加速与配体D的结合。(C)2007,JPO&INPIT
    • 2. 发明专利
    • Measuring device using total reflection attenuation
    • 使用总反射衰减测量装置
    • JP2007071837A
    • 2007-03-22
    • JP2005262362
    • 2005-09-09
    • Fujifilm Holdings Corp富士フイルムホールディングス株式会社
    • FUJIKURA TATSUO
    • G01N21/27G01N21/05G01N35/10G01N37/00
    • PROBLEM TO BE SOLVED: To prevent inclination of a sensor unit generated when inserting/extracting a pipette. SOLUTION: Inclination prevention members 85a-85d are provided on four spots on the bottom surface of a pressing part 80b of a pressing member. Each inclination prevention member 85a-85d has a wedge-shaped constitution equipped with a surface 86 orthogonal to the bottom surface 80e of the pressing part 80b and a slope 87 inclined toward the orthogonal surface 86. When the sensor unit 12 is set on a measuring position, the pressing member 80 is started to be lowered. Each line contact is generated during a lowering time, between the slope 87 of each inclination prevention member 85a, 85b and a ridgeline 12e of the sensor unit 12, and between the slope 87 of each inclination prevention member 85c, 85d and a ridgeline 12c of the sensor unit 12. Hereby, the sensor unit 12 is held in the pressed state onto a rail 70. COPYRIGHT: (C)2007,JPO&INPIT
    • 要解决的问题:为了防止在插入/拔出移液管时产生的传感器单元的倾斜。 解决方案:倾斜防止构件85a-85d设置在按压构件的按压部80b的底面上的四个点上。 每个倾斜防止构件85a-85d具有楔形构造,其具有与按压部80b的底面80e正交的表面86和朝向正交表面86倾斜的斜面87.当传感器单元12设置在测量 位置时,按压部件80开始降低。 每个线接触在下降时间,每个倾斜防止构件85a,85b的斜面87与传感器单元12的脊线12e之间以及各个倾斜防止构件85c,85d的斜面87和脊线12c之间产生 传感器单元12.因此,传感器单元12被保持在按压状态到轨道70上。版权所有:(C)2007,JPO&INPIT
    • 3. 发明专利
    • Dispenser
    • 饮水机
    • JP2007064942A
    • 2007-03-15
    • JP2005255012
    • 2005-09-02
    • Fujifilm Holdings Corp富士フイルムホールディングス株式会社
    • MURAISHI KATSUAKIFUJIKURA TATSUOTAKAI SHINYA
    • G01N35/10G01N21/27
    • B01L3/021B01L2200/022B01L2300/0829G01N21/553G01N35/1095
    • PROBLEM TO BE SOLVED: To provide a dispenser for selectively lowering a pair of pipettes in suction and measurement of liquid. SOLUTION: The pair of pipettes are constituted of suction/delivery pipettes 30 to be used in suction and measurement of the liquid, and the pipettes 35 for suction to be used only in measurement. The suction/delivery pipettes 30 are provided on the first head 101, and the pipettes 35 for suction are provided on the second head 102. The first head 101 is freely elevatable to the holding part 111, and the second head 102 is provided freely elevatable to the first head 101. At the liquid suction position by the blocking rods 141, the lowering of the second head 102 is blocked, so only the first head 101 is lowered. In the measurement time, the second head 102 is lowered following to the lowering of first head 101, because no blocking rod is arranged. COPYRIGHT: (C)2007,JPO&INPIT
    • 要解决的问题:提供一种用于在抽吸和测量液体中选择性地降低一对移液管的分配器。 解决方案:一对移液管由用于抽吸和测量液体的抽吸/输送移液管30和用于吸入的移液管35仅用于测量。 吸入/输送移液管30设置在第一头101上,用于吸引的移液管35设置在第二头102上。第一头101可自由地升高到保持部111,并且第二头102设置成可自由升高 通过阻挡杆141在液体吸入位置处,第二头部102的下降被阻挡,因此仅第一头部101降低。 在测量时间中,由于没有设置阻挡杆,第二头102随着第一头101的下降而下降。 版权所有(C)2007,JPO&INPIT
    • 4. 发明专利
    • Passage block, sensor unit, and measuring device utilizing total reflection attenuation
    • 通道块,传感器单元和使用总反射衰减的测量装置
    • JP2007010439A
    • 2007-01-18
    • JP2005190770
    • 2005-06-29
    • Fujifilm Holdings Corp富士フイルムホールディングス株式会社
    • OGURA NOBUHIKOSHIMIZU HITOSHIFUJIKURA TATSUOKURUMA KOJI
    • G01N21/27G01N21/05G01N21/11G01N21/17G01N21/41G01N33/543
    • G01N21/553G01N21/05
    • PROBLEM TO BE SOLVED: To suppress an influence of nonspecific adsorption without preventing throughput heightening of a sensor unit.
      SOLUTION: Two passages 20, 21 are formed in a passage member 12. Each of passages 20, 21 is formed approximately in a U-shape by linear groove parts 20c, 21c formed on the bottom surface of the passage member 12 and sending/discharging liquid pipes 20d, 20e and 21d, 21e for forming a gateway to each of groove parts 20c, 21c penetratingly upward from both ends of each of groove parts 20c, 21c. Each of groove parts 20c, 21c is set along the longitudinal direction of a body 12a, overlapping partially in the longitudinal direction. Hereby, each of passages 20, 21 can be densely arranged, and provision for acquiring a measuring signal and a reference signal by dividing the passages does not cause enlargement of the sensor unit, throughput heightening is not prevented.
      COPYRIGHT: (C)2007,JPO&INPIT
    • 要解决的问题:抑制非特异性吸附的影响而不防止传感器单元的通过量增加。 解决方案:在通道构件12中形成两个通道20,21。每个通道20,21通过形成在通道构件12的底表面上的直线槽部分20c,21c形成为大致U形, 从每个槽部20c,21c的两端向上方突出地向每个槽部20c,21c形成用于形成通道的液体管20d,20e,21d,21e。 每个槽部20c,21c沿主体12a的长度方向设置,在长度方向上部分重叠。 因此,通道20,21中的每一个可以密集地布置,并且通过分割通道来获取测量信号和参考信号的设置不会导致传感器单元的放大,不能防止通过量增加。 版权所有(C)2007,JPO&INPIT
    • 5. 发明专利
    • Sensor unit
    • 传感器单元
    • JP2007003464A
    • 2007-01-11
    • JP2005186598
    • 2005-06-27
    • Fujifilm Holdings Corp富士フイルムホールディングス株式会社
    • FUJIKURA TATSUO
    • G01N21/27G01N21/11G01N35/02
    • PROBLEM TO BE SOLVED: To provide a sensor unit capable of keeping high adhesiveness by preventing application of a stress onto a prism and a passage member.
      SOLUTION: This sensor unit 12 used for a measuring device utilizing total reflection attenuation comprises the prism 21 and the passage member 22. A metal film (thin film layer) 26 is formed on the upper surface of the prism 21. A passage 31 for sending liquid to the metal film 26 is formed on the passage member 22. Since the bottom surface of the passage member 22 and the upper surface of the prism 21 are bonded together by laser welding or the like, a holding member or the like is not required, and a stress is not applied.
      COPYRIGHT: (C)2007,JPO&INPIT
    • 要解决的问题:提供一种能够通过防止在棱镜和通道构件上施加应力而能够保持高粘合性的传感器单元。 解决方案:用于使用全反射衰减的测量装置的传感器单元12包括棱镜21和通道构件22.金属膜(薄膜层)26形成在棱镜21的上表面上。通道 在通道构件22上形成用于将液体送到金属膜26的31.由于通道构件22的底表面和棱镜21的上表面通过激光​​焊接等粘接在一起,保持构件等 不需要,不施加压力。 版权所有(C)2007,JPO&INPIT
    • 6. 发明专利
    • Dispensing device
    • 分配设备
    • JP2007071838A
    • 2007-03-22
    • JP2005262364
    • 2005-09-09
    • Fujifilm Holdings Corp富士フイルムホールディングス株式会社
    • FUJIKURA TATSUO
    • G01N35/10
    • PROBLEM TO BE SOLVED: To prevent inclination of a sensor unit when inserting a pipette chip into a liquid sending tube. SOLUTION: A position adjusting part 73 is provided on a nozzle 60 constituting a pipette head 51, and disposed in a hollow part 81 of a guide part 80 provided rigidly. When the pipette head 51 is lowered in the D-direction in the figure toward a sensor cell set on a measuring position, if the tip of the pipette chip 50 abuts on a tapered face 42c of an introduction port 42b, the tip of the pipette chip 50 is rust-jointed onto the tapered face 42c. In this case, since the hollow part 81 of the guide part 80 is larger than the position adjusting part 73, the pipette head 51 is slid in the E-direction in the figure. Hereby, the tip of a pipette 25 is inserted into an injection port 16a in the state where the center of the pipette chip 50 agrees with the center of the injection port 16a. COPYRIGHT: (C)2007,JPO&INPIT
    • 要解决的问题:为了防止在将移液管芯片插入送液管时传感器单元的倾斜。 解决方案:在构成移液管头51的喷嘴60上设置位置调节部73,并且设置在刚性地设置的引导部80的中空部81中。 当移液管头51沿着图中的D方向朝着设置在测量位置的传感器单元下降时,如果移液管芯片50的尖端与导入口42b的锥形面42c抵接,则移液管的尖端 芯片50在锥面42c上生锈接合。 在这种情况下,由于引导部80的中空部81大于位置调整部73,因此吸头51沿图中的E方向滑动。 因此,在移液管芯片50的中心与注射口16a的中心一致的状态下,将移液管25的前端插入注射口16a。 版权所有(C)2007,JPO&INPIT