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1. 发明专利

JP2013201968A Lactobacillus/acidophilus-containing food and beverage 审中-公开
标题翻译： Lactobacillus /含有食物的食物和饮料
公开(公告)号：JP2013201968A
公开(公告)日：2013-10-07
申请号：JP2012074264
申请日：2012-03-28
申请人： Calpis Co Ltd , カルピス株式会社
发明人： HIROTA TATSUHIKO , GOTO HIROAKI
IPC分类号： A23L1/30 , A23L2/52
摘要： PROBLEM TO BE SOLVED: To provide a food and beverage composition which is excellent in safety, capable of being used continuously, further improved in useful effect such as antiallergic action of lactobacillus belonging to lactobacillus/acidophilus, and expected to develop the effect in a short period of time: and to provide lactobacillus/acidophilus-containing food and beverage using the composition.SOLUTION: A food and beverage composition contains lactobacillus belonging to lactobacillus/acidophilus, and edible raw material being other than the lactobacillus and showing antiallergic action through oral intake, and is usable for various kinds of beverages and various kinds of foods such as candy, ice cream and powdered milk.
摘要翻译：要解决的问题：提供一种安全性优异，能够连续使用的食品饮料组合物，进一步提高有用效果，例如属于乳酸杆菌/嗜酸乳杆菌的乳杆菌的抗过敏作用，并预期在短时间内产生效果一段时间：使用该组合物提供含乳酸菌/含嗜酸菌的食品和饮料。解决方案：食品和饮料组合物含有属于乳酸杆菌/嗜酸乳杆菌的乳杆菌，以及不同于乳杆菌的可食用原料，通过口服摄取显示抗过敏作用，可用于各种饮料和各种食品如糖果，冰淇淋和奶粉。

2. 发明专利

JP2012031139A Peptide which has cerebral function improvement action 有权
标题翻译：已经进行了胚胎功能改善的肽
公开(公告)号：JP2012031139A
公开(公告)日：2012-02-16
申请号：JP2011119960
申请日：2011-05-30
申请人： Calpis Co Ltd , カルピス株式会社
发明人： OSAWA KAZUHITO , UCHIDA NAOTO , OKI KOJI , GOTO HIROAKI
IPC分类号： C07K7/00 , A61K38/00 , A61P25/18 , A61P25/24 , A61P25/28 , C07K14/00
CPC分类号： A61K38/04 , C07K7/08
摘要： PROBLEM TO BE SOLVED: To provide a composition for improving the brain function.SOLUTION: The peptide contains X-Pro-Pro-Leu-Thr-Gln-Thr-Pro-Val-Val-Val-Pro-Pro-Phe-Leu-Gln-Pro-Glu-Y (wherein (i) X represents Asn-Ile; and Y is nil or represents Val-Met or (ii) X is nil or represents Ile and Y is nil) or the peptide contains X-Val-Val-Val-Pro-Pro-Phe-Leu-Gln-Pro-Glu (wherein X is nil or represents Leu-Thr-Gln-Thr-Pro or Pro) or a salt of the same.
摘要翻译：要解决的问题：提供用于改善脑功能的组合物。解决方案：肽含有X-Pro-Pro-Leu-Thr-Gln-Thr-Pro-Val-Val-Val-Pro-Pro-Phe-Leu-Gln-Pro-Glu-Y（其中（i） X表示Asn-Ile; Y为零或表示Val-Met，或（ii）X为无或表示Ile，Y为无）或肽含有X-Val-Val-Val-Pro-Pro-Phe-Leu- Gln-Pro-Glu（其中X为无或表示Leu-Thr-Gln-Thr-Pro或Pro）或其盐。版权所有（C）2012，JPO＆INPIT

3. 发明专利

JP2013005757A Production method of casein-derived peptide by lactic acid fermentation 有权
标题翻译：通过酸化发酵生产蛋白衍生肽的方法
公开(公告)号：JP2013005757A
公开(公告)日：2013-01-10
申请号：JP2011140737
申请日：2011-06-24
申请人： Calpis Co Ltd , カルピス株式会社
发明人： UCHIDA NAOTO , GOTO HIROAKI , OSAWA KAZUHITO , OKI KOJI
IPC分类号： C12P21/02 , A23L1/305 , A61K38/00 , A61P25/28 , C07K7/08 , C07K14/00 , C12N1/20
CPC分类号： C07K14/4732 , A23L33/17 , A23L33/18 , A23L33/19 , A61K38/00 , C07K7/06 , C07K7/08 , C12P21/06
摘要： PROBLEM TO BE SOLVED: To provide a simple and efficient method for producing a safer chemical compound which prevents and ameliorates conditions and ailments caused by a deterioration in brain function and is suitable for use in medicines and food products.SOLUTION: The production method of a peptide composed of an amino acid sequence set forth in one of sequence Nos.1-4 and 16 includes: fermenting mammalian milk or milk protein using at least one lactic acid bacterium and/or a processed product thereof, and extracting the peptide from the resultant fermented milk.
摘要翻译：要解决的问题：提供一种简单有效的方法来制备更安全的化合物，其防止和改善由脑功能的恶化引起的病症和疾病，并且适用于药物和食品。解决方案：由序列号1-4和16中任一项所述的氨基酸序列构成的肽的制备方法包括：使用至少一种乳酸菌和/或加工的发酵哺乳动物乳或乳蛋白产物，并从所得发酵乳中提取肽。版权所有（C）2013，JPO＆INPIT

4. 发明专利

JP2013005763A Enzymatic production method for brain-function-improving peptide 有权
标题翻译：用于脑功能改善肽的酶促生产方法
公开(公告)号：JP2013005763A
公开(公告)日：2013-01-10
申请号：JP2011141101
申请日：2011-06-24
申请人： Calpis Co Ltd , カルピス株式会社
发明人： UCHIDA NAOTO , GOTO HIROAKI , OSAWA KAZUHITO , OKI KOJI
IPC分类号： C12P21/06 , A23L1/305 , A61K38/00 , A61K38/17 , A61P25/28 , C07K1/12 , C07K14/47
CPC分类号： C12N9/52 , A23J3/344 , A23L2/66 , A23L33/17 , A23L33/19 , A61K38/018 , A61K38/04 , C07K14/47 , C07K14/4732 , C12P21/06
摘要： PROBLEM TO BE SOLVED: To provide an enzymatic production method for a brain-function-improving peptide.SOLUTION: The method for producing a brain-function-improving peptide includes: hydrolysing milk casein by an enzymatic catalyst including a protease to produce a hydrolysate including (i) a peptide including a specific amino acid sequence or a peptide including an amino acid sequence including deletion, substitution or addition of one or two amino acid residues in this amino acid sequence; (ii) a peptide including another specific amino acid sequence or a peptide including an amino acid sequence including deletion, substitution or addition of one or two amino acid residues in this amino acid sequence set; or (iii) a mixture of the peptides of (i) and (ii). The generation yield of each of the peptides is at least 2% or the total generation yield of the mixture is at least 10%. A food product, drink, or medicinal composition including the hydrolysate is also provided.
摘要翻译：待解决的问题：提供脑功能改善肽的酶促制备方法。解决方案：制备脑功能改善肽的方法包括：通过包括蛋白酶的酶催化剂水解乳酪蛋白以产生水解产物，其包括（i）包含特定氨基酸序列的肽或包含氨基酸的肽酸序列，包括在该氨基酸序列中缺失，取代或添加一个或两个氨基酸残基; （ii）包含其他特定氨基酸序列的肽或包含氨基酸序列的肽，所述氨基酸序列包括在该氨基酸序列组中缺失，取代或添加一个或两个氨基酸残基; 或（iii）（i）和（ii）的肽的混合物。每种肽的产生产率至少为2％，或者混合物的总代谢产率为至少10％。还提供了包含水解产物的食品，饮料或药用组合物。版权所有（C）2013，JPO＆INPIT

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