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1. 发明专利

JPH03197840A PARTICLE ANALYZING DEVICE 失效
公开(公告)号：JPH03197840A
公开(公告)日：1991-08-29
申请号：JP33762289
申请日：1989-12-26
申请人： CANON KK
发明人： ITO YUJI
IPC分类号： G01N33/48 , G01N15/14
摘要： PURPOSE:To detect more detailed type information on particles to be inspected by making a scan with a light beam in a direction intersecting a flow of particles to be inspected and detecting the polarized light of scattered light or fluorescent light from the particles to the inspected in a specific direction. CONSTITUTION:The laser beam L projected by a light source 4 is deflected by an optical deflecting element 16 and then converged 18 to irradiate the distribution part 3a of a flow cell 3. The input signal of the element 16 is controlled to scan a different position of the particles S0 to be inspected with the beam L. The forward scattered light from the distribution part 3a is photodetected by a photodetector 32 through a condenser lens 19. The sideward scattered light is passed through a condenser lens 23, transmitted through a half-mirror 24, and photodetected by a photodetector 26. Luminous flux is reflected by a mirror 24 and only its luminous flux which is polarized in a direction crossing the deflection direction at right angles is photodetected by a photodetector 29 as polarized light extinction light. The polarized light extinction light is generated by the anisotropic structure in the particles S0, the multiple scattering, etc., of the beam L, so the more detailed type information on the particles S0 is obtained from the photodetection information.

2. 发明专利

JPH02138851A PARTICLE MEASURING APPARATUS 失效
公开(公告)号：JPH02138851A
公开(公告)日：1990-05-28
申请号：JP29156688
申请日：1988-11-18
申请人： CANON KK
发明人： MIYAMOTO MORITOSHI , ITO YUJI
IPC分类号： G01N15/14
摘要： PURPOSE:To obtain highly accurate information concerning a shape by a method wherein first and second photometry means to measure scattered light due to sample particles arranged at a position to which first and second light irradiation means correspond and output values of both the photometry means are compared with a comparison means and an identification is performed to determine whether the sample particles are spherical or not spherical from the results of the comparison. CONSTITUTION:A first light irradiation means is composed of a laser light source 1 with a wavelength lambda1 of a particle measuring device and an image forming optical system 3 while a second light irradiation means is composed of a laser light source 11 with a wavelength lambda2 and an image forming optical system 13. Irradiation light from both the irradiation means is made to irradiate the sample particles flowing sequentially through a passage section 2 within a flowcell 4 and scattered light from the sample particles is detected selectively first and second photo detectors 10 and 18 arranged in respective optical axes. Detection outputs thereof are stored into first and second memory sections of a memory means 19 in such a manner that a larger data and a smaller data correspond to the first and second memory sections among detection data from one sample particle and values thereof are computed by a computing means 20 to determine a shape of the sample particle.

3. 发明专利

JPH01305338A PARTICLE ANALYZING APPARATUS 失效
公开(公告)号：JPH01305338A
公开(公告)日：1989-12-08
申请号：JP13681388
申请日：1988-06-02
申请人： CANON KK
发明人： ITO YUJI
IPC分类号： G01N15/14
摘要： PURPOSE:To facilitate alignment operation and the replacement of members and to enable automation of an apparatus by integrating a part of an optical member with a flow cell. CONSTITUTION:A laser beam from a laser light source is imaged by an imaging lens 17 and irradiates specimen particles flowing through a circulation element 1a of a flow cell 1. A forward scattered light thereof is made to enter a photodetector 8 through a condenser lens 7 and information on the size of the specimen particle is obtained therefrom mainly. Besides, a 90 deg. scattered light and fluorescence from the specimen particles are made to enter a photodetector 13 through a condenser lens 9 and an information on the shape of the specimen particle is obtained therefrom mainly. Since the flow cell 1 and the lenses 17, 7 and 9 are retained by the same retaining member 16 in this constitution, alignment is completed only by adjusting the light source 4 and detector retaining members 21 and 22 for the two detectors 8 and 13 beforehand in relation to the position whereat the specimen particles inside the circulation element 1a flows.

4. 发明专利

JPH01207663A METHOD AND INSTRUMENT FOR SAMPLE INSPECTION 失效
公开(公告)号：JPH01207663A
公开(公告)日：1989-08-21
申请号：JP3348288
申请日：1988-02-15
申请人： CANON KK
发明人： ITO YUJI
IPC分类号： G01N21/51 , G01N21/53 , G01N33/543
摘要： PURPOSE:To increase the efficiency of immunity inspection by measuring light beams which are scattered by carrier particles in 1st and 2nd directions, detecting the aggregation state and kind of the carrier particles, and inspecting the antigen or antibody of the sample to be inspected. CONSTITUTION:A sample liquid container 15 and a sheath liquid container 14 are raised in pressure and sample liquid flows in a flow cell 4 while sheathed with sheath liquid. At this time, individual latex particles contained in the sample liquid are separated and flow in order. Those latex particles are irradiated with the laser light from a laser light source 1 and the light is converged through cylindrical lenses 2 and 3 to generate scattered light. The front scattered light of this scattered light is measured by a photodetector 6 through a condenser lens 5. Further, the sideward scattered light is converged 7, reflected 8, and measured by a photodetector 11. Further, green fluorescent light which is reflected 9 with respect to fluorescent light passed through a mirror 8 is detected by a photodetector 12 and red fluorescent light which is reflected 10 is detected by a photodetector 13. The signals of the detectors 6, and 11-13 are inputted to an arithmetic circuit to perform analyze the particles.

5. 发明专利

JPS63217318A OPTICAL SCANNER 失效
公开(公告)号：JPS63217318A
公开(公告)日：1988-09-09
申请号：JP5177387
申请日：1987-03-05
申请人： CANON KK
发明人： ITO YUJI
IPC分类号： G02B26/12 , G02B26/10 , H04N1/04 , H04N1/113 , H04N1/23
摘要： PURPOSE:To reduce the influence of the cutting of a scanning surface upon the shape of a spot scanning on a screen and to reduce a subscanning-direction irregularity due to the distortion of the spot shape by controlling light other than the light of 0th order of an optical scanner. CONSTITUTION:A laser beam 2 from a laser light source 1 is compressed by a beam compressor 3 to a proper beam diameter, its intensity is A/O-modulated 4, and the projection diameter is varied by a beam expander 5 to the image formation size of a recording film 11. This light beam is made incident on a polygon mirror 9 through a reflecting mirror 6 and a cylindrical lens 7. A beam B from this rotating mirror 9 is made incident on an Ftheta lens 10 to scan the film 11 on a rotary drum 12. A half-mirror M1 is arranged between this lens 7 and mirror 9 and a half-mirror M2 is arranged on the optical path of the beam B from the mirror 9. Then a light beam size control means 5 prevents light which is incident on and diffracted by the lens 10 according to the pitch of the mirror 9 except the light of 0th order from being mixed.

6. 发明专利

JPS63212329A BLOOD FLOWMETER 失效
公开(公告)号：JPS63212329A
公开(公告)日：1988-09-05
申请号：JP4634887
申请日：1987-02-28
申请人： CANON KK
发明人： ITO YUJI
IPC分类号： A61B5/026 , A61B5/02 , B41J13/00 , B65H3/06 , B65H3/52

7. 发明专利

JPS63201554A PARTICLE ANALYZING DEVICE 失效
公开(公告)号：JPS63201554A
公开(公告)日：1988-08-19
申请号：JP3407887
申请日：1987-02-17
申请人： CANON KK
发明人： ITO YUJI
IPC分类号： G01N21/64 , G01N15/14 , G01N21/53
摘要： PURPOSE:To measure accurate flow velocity regardless of the size of a particle to be inspected by providing a light intensity distribution which is separated into >=2 to a light beam projected on a detection part. CONSTITUTION:Sample liquid 11 made to flow toward the flow cell 1 at the center part of a container part 9 through a tube 10 is covered with sheath liquid 13 flowing in sideward through a tube 12. The beam from a laser light source 2 is shaped by a beam expander 13 to proper size and then diffracted by a diffraction grating 4 to form a spectrum image which has plural separated intensity distributions B1-B3 in the flow cell 1 through an image forming lens 5. When a stopper 6 cuts off light of a normal image forming beam, only scattered light is obtained and guided to a photodetector 8 through a condenser lens 7. Times t1 and t2 when a signal waveform obtained by letting the particle S to be inspected cross pieces of luminous flux B1-B3 has its peak are found to obtain the speed.

8. 发明专利

JPS63165815A OPTICAL SCANNER 失效
公开(公告)号：JPS63165815A
公开(公告)日：1988-07-09
申请号：JP31268286
申请日：1986-12-27
申请人： CANON KK
发明人： ITO YUJI
IPC分类号： G02B26/12 , G02B26/10
摘要： PURPOSE:To reduce the influence of uneven cutting to be exerted upon a scanning mirror surface by arranging a 1st slit having long sides in an optical beam scanning direction and short sides in its rectangular direction between a scanning mirror and an image forming optical system and arranging a 2nd slit in front of an image forming face. CONSTITUTION:In the optical scanner, a slit A is arranged between a polygon mirror 9 and an image formation lens 10 and a slit B is arranged between the lens 10 and a recording film 11. The slits A, B are the means for restricting diffraction beam component in the direction intersecting with the scanning direction and their aperture are formed so as to have long sides in the scanning direction and short sides in the intersecting direction. When laser beams are radiated from a light source 1 to the polygon mirror 9, diffraction is generated by the uneven cutting work on the reflecting face of the mirror 9, but the influence of the uneven cutting to be exerted upon the scanning mirror surface can be reduced by arranging the slits A, B for transmitting 0th-order diffraction light.

9. 发明专利

JPS6396537A GRAIN ANALYZER 失效
公开(公告)号：JPS6396537A
公开(公告)日：1988-04-27
申请号：JP24474386
申请日：1986-10-14
申请人： CANON KK
发明人： ITO YUJI
IPC分类号： G01N15/14 , G01N21/53 , G01N33/49
摘要： PURPOSE:To easily execute an alignment focus adjustment by providing a reticle on a conjugated position of a grain to be inspected, of a photodetecting or photometric system. CONSTITUTION:A flow part 1a of a sample, and a laser light source 2 are provided on the center part of a flow cell 1, and one side, respectively. An image formation optical system 3 is placed along an optical axis of a laser light which is emitted, and an objective lens 4 and a photodetector 5 are placed on the opposite side of the flow cell 1. Also, in the direction orthogonal to the optical axis of the laser light and the flow direction of the flow part 1a, respectively, an objective lens 6, a reticle 7, a condensing lens 8, dichroic mirrors 9, 10, a condensing lens 11, a barrier filter 12, and a photodetector 13 are arranged successively. The reticle 7 is provided on a rotary late 21 together with an aperture 20, so that it can move selectively by a motor 22. The reticle 7 is installed to a conjugate position to the flow part 1a with regard to the objective lens 6.

10. 发明专利

JPS6359930A BLOOD FLOW METER 失效
公开(公告)号：JPS6359930A
公开(公告)日：1988-03-15
申请号：JP20453186
申请日：1986-08-30
申请人： CANON KK
发明人： ITO YUJI
IPC分类号： A61B5/026 , A61B5/02

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