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    • 3. 发明专利
    • Skin care preparation
    • 皮肤护理准备
    • JP2012006875A
    • 2012-01-12
    • JP2010144778
    • 2010-06-25
    • Shiseido Co Ltd株式会社 資生堂
    • OZAWA HIROAKIHASEGAWA SAYOKOHIRUMA YUKIKOARAKI HIDEFUMIMEYA TAKATSUGUYOSHIKAWA NORINOBUNOMURA TOMONORI
    • A61K8/25A61K8/81A61Q15/00
    • PROBLEM TO BE SOLVED: To provide a skin care preparation obtained by mixing silver ion-carrying antimicrobial zeolite with water and a polymer having a polyacrylic acid amide skeleton, which has remarkably improved dispersion stability of silver ion-carrying antimicrobial zeolite powder without causing discoloring and a liquid skin care preparation especially mixed with a large amount of water, which secures discoloration stability and/or dispersion stability and is stable.SOLUTION: The skin care preparation comprises the polymer having the polyacrylic acid amide skeleton that is a thickener composed of microgel obtained by dissolving dimethylacrylamide and 2-acrylamide-2-methylpropanesulfonic acid or its salt in a dispersion phase and performing radical polymerization in the dispersion phase in a composition comprising an organic solvent or an oil as a dispersion medium and water as the dispersion phase under a condition that the composition contains a surfactant and forms a single phase microemulsion or a fine W/O emulsion.
    • 待解决的问题:提供通过将含银离子的抗微生物沸石与水和具有聚丙烯酸酰胺骨架的聚合物混合而获得的护肤制剂,其具有显着提高的带有银离子的抗微生物沸石粉末的分散稳定性,而没有 导致变色和特别与大量水混合的液体护肤制剂,其确保变色稳定性和/或分散稳定性并且稳定。 皮肤护理制剂包括具有聚丙烯酸酰胺骨架的聚合物,其是由分散相中将二甲基丙烯酰胺和2-丙烯酰胺-2-甲基丙磺酸或其盐溶解并进行自由基聚合而获得的微凝胶组成的增稠剂 在包含有机溶剂或油作为分散介质的组合物中的分散相以及水作为分散相,在组合物含有表面活性剂并形成单相微乳液或细W / O乳液的条件下。 版权所有(C)2012,JPO&INPIT
    • 5. 发明专利
    • Skin care preparation
    • 皮肤护理准备
    • JP2012006859A
    • 2012-01-12
    • JP2010143451
    • 2010-06-24
    • Shiseido Co Ltd株式会社 資生堂
    • OZAWA HIROAKIHASEGAWA SAYOKOHIRUMA YUKIKOARAKI HIDEFUMIMEYA TAKATSUGUYOSHIKAWA NORINOBUNOMURA TOMONORI
    • A61K8/25A61K8/02A61K8/04A61K8/06A61K8/19A61K8/27A61K8/34A61K8/46A61K8/81A61Q15/00
    • PROBLEM TO BE SOLVED: To provide a skin care preparation obtained by mixing silver ion-carrying antimicrobial zeolite with ethanol, which has remarkably improved dispersion stability of silver ion-carrying antimicrobial zeolite powder without causing discoloring and a liquid skin care preparation mixed with silver ion-carrying antimicrobial zeolite powder especially treated with an MQ resin, which prevents flocculation and discoloration of the antimicrobial zeolite powder, secures redispersibility and is stable.SOLUTION: The skin care preparation is obtained by mixing (a) 0.001-20 mass%, based on the total of the skin care preparation, of silver ion-carrying antimicrobial zeolite with (b) 50-99.6 mass%, based on the total of the skin care preparation, of ethanol, (c) 0-50 mass%, based on the total of the skin care preparation, of water and (d) 0.2-4 mass%, based on the total of the skin care preparation, of a polymer having a polyacrylic acid amide skeleton.
    • 待解决的问题:提供通过将含银离子的抗微生物沸石与乙醇混合而获得的护肤制剂,其显着提高了携带银离子的抗微生物沸石粉末的分散稳定性而不引起褪色,并且液体护肤制剂混合 具有特别用MQ树脂处理的银离子携带抗微生物沸石粉末,其防止抗微生物沸石粉末的絮凝和变色,确保再分散性并且稳定。 解决方案:通过将(a)基于皮肤护理制剂的总量的0.001-20质量%的带银离子的抗微生物沸石与(b)基于50-99.6质量% 对皮肤护理制剂,乙醇的总量,(c)0-50质量%,基于皮肤护理制剂的总和,和(d)0.2-4质量%,基于皮肤总量 护理制备具有聚丙烯酸酰胺骨架的聚合物。 版权所有(C)2012,JPO&INPIT
    • 7. 发明专利
    • Skin external preparation
    • 外用皮肤制剂
    • JP2010159214A
    • 2010-07-22
    • JP2009000663
    • 2009-01-06
    • Shiseido Co Ltd株式会社資生堂
    • KAMIYA YUKIKOARAKI HIDEFUMIMEYA TAKATSUGUYOSHIKAWA NORINOBUNOMURA TOMONORI
    • A61K8/26A61K8/06A61K8/19A61K8/46A61K8/81A61Q15/00A61Q19/00
    • PROBLEM TO BE SOLVED: To provide an external preparation for the skin, obtained by formulating silver ion-carrying antimicrobial zeolite and water, hardly causing discoloration, and having extremely improved dispersion stability of the silver ion-carrying antimicrobial zeolite powder. SOLUTION: The external preparation for the skin is obtained by further formulating a polymer having a polyacrylic acid amide skeleton with the external preparation for the skin obtained by formulating the silver ion-carrying antimicrobial zeolite and the water. The preferable polymer having the polyacrylic acid amide skeleton is a thickener comprising a microgel obtained by dissolving dimethylacrylamide and 2-acrylamido-2-methylpropanesulfonic acid or a salt thereof in a dispersion phase under a condition of the composition containing a surfactant and forming a single phase microemulsion or a fine W/O emulsion, and carrying out a radical polymerization in the dispersion phase. COPYRIGHT: (C)2010,JPO&INPIT
    • 要解决的问题:为了提供通过配制带有银离子的抗微生物沸石和水而获得的皮肤的外用制剂,几乎不引起变色,并且具有非常提高的带有银离子的抗微生物沸石粉末的分散稳定性。 解决方案:通过进一步配制具有聚丙烯酸酰胺骨架的聚合物,通过配制载有银离子的抗微生物沸石和水而获得的皮肤外用制剂,获得外用皮肤制剂。 具有聚丙烯酸酰胺骨架的优选聚合物是包含通过将二甲基丙烯酰胺和2-丙烯酰胺基-2-甲基丙磺酸或其盐在含有表面活性剂的组合物形成单相的条件下在分散相中溶解获得的微凝胶的增稠剂, 微乳液或细W / O乳液,并在分散相中进行自由基聚合。 版权所有(C)2010,JPO&INPIT