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1. 发明专利

JP2015029793A 放射線治療システム有权
标题翻译：放射治疗系统
公开(公告)号：JP2015029793A
公开(公告)日：2015-02-16
申请号：JP2013162656
申请日：2013-08-05
申请人：株式会社日立製作所 , Hitachi Ltd , 国立大学法人北海道大学 , Hokkaido Univ
发明人： UMEKAWA TORU , HIRAMOTO KAZUO , BABA RIKA , SASAKI YOSHIE , NAGAMINE YOSHIHIKO , SHIMIZU SHINICHI , TAKAO SEISHIN , MIYAMOTO NAOKI , MATSUURA TAEKO , UMEGAKI KIKUO
IPC分类号： A61N5/10 , A61B6/02 , A61B6/03 , A61B6/12
CPC分类号： A61B6/032 , A61B6/5294 , A61B6/541 , A61N5/1049 , A61N5/1081 , A61N2005/1061
摘要：【課題】放射線治療の患者位置決めにおいて必要とされる、治療放射線照射状態での標的や放射線通過領域、及び危険臓器の位置関係を把握可能な画像を取得することができる放射線治療システムを提供する。【解決手段】放射線治療システムは、回転しながら複数の方向から被検体にX線を照射しX線撮影するX線撮影装置45と、X線撮影装置45によって取得したX線画像から被検体1内の標的2の3次元位置を認識する標的認識装置9と、X線撮影装置45によって取得したX線画像の中から、標的認識装置9によって認識した標的2の位置が動体追跡治療の治療放射線照射条件を満たす画像を選択して画像再構成を行い、コーンビームCT画像を生成するCT画像生成装置10,11,12とを備える。【選択図】図1A
摘要翻译：要解决的问题：提供一种能够捕获图像的放射治疗系统，其有助于了解治疗射线照射状态，放射线通过区域和定位患者进行放射治疗所需的关键器官的位置关系。解决方案：放射治疗系统包括：X射线成像装置45，其通过在旋转时从多个方向照射被检体的X射线进行X射线成像; 由X射线摄像装置45拍摄的X射线图像识别对象1中的目标2的三维位置的目标识别装置9; 以及CT图像生成装置10,11,12，其从由X射线摄像装置45拍摄的X射线图像中选择由目标识别装置9识别的目标2的位置满足处理的图像用于运动身体跟踪处理的放射线照射条件进行图像重建并产生锥形束CT图像。

2. 发明专利

JP2014144122A Particle beam treatment system 有权
标题翻译：颗粒束处理系统
公开(公告)号：JP2014144122A
公开(公告)日：2014-08-14
申请号：JP2013014153
申请日：2013-01-29
申请人： Hitachi Ltd , 株式会社日立製作所 , Hokkaido Univ , 国立大学法人北海道大学
发明人： TAKAYANAGI TAISUKE , MATSUDA KOJI , SHINAGAWA RYOSUKE , NAKAJIMA CHIHIRO , NISHIMURA ARAO , SHIRATO HIROKI , MATSUURA TAEKO , SHIMIZU SHINICHI , ONIMARU RIKIYA , UMEGAKI KIKUO
IPC分类号： A61N5/10
CPC分类号： A61N5/1043 , A61N5/10 , A61N5/1031 , A61N5/1045 , A61N5/1065 , A61N5/1077 , A61N5/1081 , A61N2005/1087 , A61N2005/1095
摘要： PROBLEM TO BE SOLVED: To improve penumbra in a short-range region without being accompanied by increase in costs, increase in penumbra in the outside of the short-range region, and increase in burden imposed on an operator, in a particle beam treatment system using a scanning irradiation method.SOLUTION: A particle beam treatment system comprises an irradiation compensator 101 targeted for a short-range region composed of an energy absorber 302, a first collimator 303, and a second collimator 304. The irradiation compensator 101 includes an attaching/detaching mechanism for the energy absorber 302, the first collimator 303, and the second collimator 304. The first collimator 303 is disposed in an upstream side where the beam diameter is small to help restrain the breadth of the compensator 101, thereby contributing the size reduction and weight saving of the compensator 101. The second collimator 304 is disposed in a downstream side, thereby contributing to the improvement of penumbra.
摘要翻译：要解决的问题：为了在短距离区域内改善半影，而不伴随着成本的增加，在短距离区域外的半暗带的增加以及对操作者施加的负担的增加，在粒子束处理系统使用扫描照射方法。解决方案：粒子束处理系统包括针对由能量吸收器302，第一准直器303和第二准直器304组成的短程区域的照射补偿器101.照射补偿器101包括附接 /分离机构，第一准直仪303和第二准直仪304.第一准直仪303设置在光束直径小的上游侧，以帮助抑制补偿器101的宽度，从而有助于尺寸补偿器101的减少和重量减轻。第二准直器304设置在下游侧，从而有助于半暗带的改进。

3. 发明专利

JP2014057738A Corpuscular beam irradiation system and treatment planning device 有权
标题翻译：。AR。。。。。。。。。。。。。。。。。。
公开(公告)号：JP2014057738A
公开(公告)日：2014-04-03
申请号：JP2012204767
申请日：2012-09-18
申请人： Hitachi Ltd , 株式会社日立製作所 , Hokkaido Univ , 国立大学法人北海道大学
发明人： FUJII YUSUKE , FUJIMOTO RINTARO , UMEZAWA MASUMI , MATSUURA TAEKO , MIYAMOTO NAOKI , SHIMIZU SHINICHI , TORAMATSU CHIE , TAKAO SEISHIN , NIHONGI HIDEAKI , HIRATA YUICHI , UMEGAKI KIKUO
IPC分类号： A61N5/10
CPC分类号： A61N5/1067 , A61N5/103 , A61N5/1043 , A61N5/1049 , A61N2005/1087
摘要： PROBLEM TO BE SOLVED: To provide a corpuscular beam irradiation system and a treatment planning device capable of forming dose distribution as planned and reducing irradiation time (treatment time) in a corpuscular beam irradiation system by a scanning irradiation method.SOLUTION: An operation device 101 of a treatment planning device 41 determines an emission permission range for each irradiation position. A control device 48 of a corpuscular beam irradiation system by a scanning irradiation method changes the size of the emission permission range for each irradiation position using the emission permission range for each irradiation position determined by the operation device 101 of the treatment planning device 41, and emits the corpuscular beam.
摘要翻译：要解决的问题：提供一种能够通过扫描照射方法在粒子束照射系统中按计划形成剂量分布并减少照射时间（处理时间）的红细胞束照射系统和治疗计划装置。解决方案：操作装置101 治疗计划装置41确定每个照射位置的排放允许范围。通过扫描照射方法的粒子束照射系统的控制装置48使用由处理计划装置41的操作装置101确定的每个照射位置的发射允许范围来改变每个照射位置的发射允许范围的大小，以及发射红细胞束。

4. 发明专利

JP2014161706A Particle beam therapy system and range adjustment device 审中-公开
标题翻译：颗粒束治疗系统和范围调整装置
公开(公告)号：JP2014161706A
公开(公告)日：2014-09-08
申请号：JP2013038411
申请日：2013-02-28
申请人： Hitachi Ltd , 株式会社日立製作所 , Hokkaido Univ , 国立大学法人北海道大学
发明人： FUJITAKA SHINICHIRO , UMEZAWA MASUMI , FUJIMOTO RINTARO , MATSUDA KOJI , SHIRATO HIROKI , MATSUURA TAEKO , MIYAMOTO NAOKI , NIHONGI HIDEAKI , UMEGAKI KIKUO , HIRATA YUICHI
IPC分类号： A61N5/10
CPC分类号： A61N5/1077 , A61N2005/1087 , A61N2005/1095
摘要： PROBLEM TO BE SOLVED: To provide a range adjustment device and a particle beam therapy system capable of performing scanning irradiation with improved uniformity of radiation dose to the affected part compared with the prior art, thereby solving the problem that the radiation dose distribution SOBP in a depth direction is likely to degrade from a predetermined uniform distribution in a conventional elongated Bragg peak when a target moving due to breathing is irradiated for scanning.SOLUTION: A Bragg peak is enlarged by a structure in which a ridge filter part and a range shifter part are integrally fabricated, or a range adjustment device having a structure in which a ridge filter part and a range shifter part are disposed in contact with each other, or by arranging a plurality of range adjustment devices having the aforementioned structure.
摘要翻译：要解决的问题：提供一种距离调整装置和粒子束治疗系统，其能够与现有技术相比，能够对患部进行具有改善的辐射剂量均匀性的扫描照射，从而解决了在现有技术中辐射剂量分布SOBP 当由于呼吸而导致的目标移动被照射用于扫描时，深度方向可能从常规细长布拉格峰中的预定均匀分布降解。解决方案：布拉格峰通过其中脊过滤器部分和范围移位部分整体制造的范围调整装置，或具有将脊部过滤器部分和范围移动部件彼此接触设置的结构，或通过布置具有上述结构的多个范围调节装置的范围调整装置。

5. 发明专利

JP2013111406A System and mtehod for charged particle irradiation 有权
标题翻译：充电粒子辐射的系统和麦克风
公开(公告)号：JP2013111406A
公开(公告)日：2013-06-10
申请号：JP2011262978
申请日：2011-11-30
申请人： Hitachi Ltd , 株式会社日立製作所 , Hokkaido Univ , 国立大学法人北海道大学
发明人： FUJII YUSUKE , UMEKAWA TORU , UMEZAWA MASUMI , SHIRATO HIROKI , UMEGAKI KIKUO , MIYAMOTO NAOKI , MATSUURA TAEKO
IPC分类号： A61N5/10
CPC分类号： A61N5/1068 , A61N5/1077 , A61N2005/1074 , A61N2005/1087
摘要： PROBLEM TO BE SOLVED: To provide a system and a method for charged particle irradiation which is capable of shortening the irradiation time and shortening the treatment time by performing efficient irradiation even when irregular variation occurs in an object to be irradiated during gate irradiation.SOLUTION: Beam emission is stopped by regular emission permission end signal reception by regular movement signals. In the meantime, an emission possible state maintaining function 46b is activated by emission permission end signal reception. When set standby time elapses without receiving an emission permission start signal again during standby, the operation of the emission possible state maintaining function 46b ends. A charged particle beam generator 1 decelerates the beam. Sometimes the beam emission is stopped by irregular emission permission end signal reception during irradiation. In the meantime, the emission possible state maintaining function 46b is activated by the emission permission end signal reception, and the charged particle beam generator 1 maintains an emission possible state. When the emission permission start signal is received again during standby, the beam emission is restarted.
摘要翻译：要解决的问题：提供一种带电粒子照射的系统和方法，即使在栅极照射期间待照射物体发生不规则变化时，能够缩短照射时间并缩短处理时间。
解决方案：通过常规运动信号的常规发射许可结束信号接收停止光束发射。同时，通过发射允许结束信号接收来激活发射可能状态保持功能46b。当在待机期间再次没有接收到发射许可开始信号而经过了待机时间时，可能的状态保持功能46b的操作结束。带电粒子束发生器1使光束减速。有时通过在照射期间的不规则发射允许结束信号接收来停止光束发射。同时，通过发射允许结束信号接收来激活可发射状态保持功能46b，并且带电粒子束发生器1保持发射可能状态。当在待机期间再次接收到发射许可开始信号时，重新发射光束。版权所有（C）2013，JPO＆INPIT

6. 发明专利

JP2014124206A Particle beam treatment apparatus 有权
标题翻译：颗粒束处理装置
公开(公告)号：JP2014124206A
公开(公告)日：2014-07-07
申请号：JP2012280795
申请日：2012-12-25
申请人： Hitachi Ltd , 株式会社日立製作所 , Hokkaido Univ , 国立大学法人北海道大学
发明人： NISHIMURA ARAO , MATSUDA KOJI , SHINAGAWA RYOSUKE , TAKAYANAGI TAISUKE , TADOKORO MASAHIRO , KITANI TAKAO , NIHONGI HIDEAKI , UMEGAKI KIKUO , MATSUURA TAEKO
IPC分类号： A61N5/10
CPC分类号： A61B6/542 , A61N5/1049 , A61N5/1067 , A61N5/1071 , A61N5/1075 , A61N5/1077 , A61N2005/1061 , A61N2005/1074 , A61N2005/1087 , F04C2270/041
摘要： PROBLEM TO BE SOLVED: To make it possible to highly accurately perform dose management in a particle beam treatment apparatus which captures an image of an affected part by X-ray irradiation during a treatment time, including an irradiation preparation period and an irradiation period of particle beams.SOLUTION: A particle beam treatment apparatus comprises: a particle beam generating device for generating a particle beam; an irradiation field forming device which is disposed in a treatment chamber and emits the particle beam to a target; a particle beam transport system 6 for communication between the particle beam generating device and the irradiation field forming device; an X-ray imaging device which is disposed in the treatment chamber and emits X rays and captures an image of the position of the target; a dosimeter 8 disposed at a position through which the particle beam passes in the irradiation field forming device; and a control device 400 for control such that X-ray measurement results are excluded from the measurement results of the dosimeter 8 when X-rays are emitted during a treatment time.
摘要翻译：要解决的问题：为了能够在包括照射准备期间和粒子的照射期间的处理时间内通过X射线照射捕获受影响部位的图像的粒子束处理装置中高度准确地进行剂量管理光束。解决方案：粒子束处理装置包括：粒子束产生装置，用于产生粒子束; 照射场形成装置，其设置在处理室中并将粒子束发射到靶; 用于粒子束产生装置和照射场形成装置之间的连通的粒子束传输系统6; X射线成像装置，其设置在所述治疗室中，并且发射X射线并捕获所述目标的位置的图像; 设置在所述粒子束通过所述照射场形成装置的位置处的剂量计8; 以及控制装置400，用于在处理时间期间发射X射线时，从剂量计8的测量结果中排除X射线测量结果。

7. 发明专利

JP2013198579A Charged particle irradiation system and irradiation planning device 有权
标题翻译：充电粒子辐射系统和辐射规划设备
公开(公告)号：JP2013198579A
公开(公告)日：2013-10-03
申请号：JP2012068047
申请日：2012-03-23
申请人： Hitachi Ltd , 株式会社日立製作所 , Hokkaido Univ , 国立大学法人北海道大学
发明人： FUJII YUSUKE , FUJIMOTO RINTARO , UMEZAWA MASUMI , MATSUURA TAEKO , MIYAMOTO NAOKI , SHIMIZU SHINICHI , TORAMATSU CHIE , TAKAO SEISHIN , NIHONGI HIDEAKI , HIRATA YUICHI , UMEGAKI KIKUO
IPC分类号： A61N5/10
CPC分类号： A61N5/103 , A61N5/1043 , A61N5/1049 , A61N5/1064 , A61N5/1068 , A61N2005/1087
摘要： PROBLEM TO BE SOLVED: To provide a charged particle irradiation system and irradiation planning device capable of shortening an irradiation time (a treatment time) and forming a dosage distribution as planned in a particle irradiation system by a scanning irradiation method.SOLUTION: A control system 7 implements: following irradiation for correcting an excitation current value of scanning electromagnets 31 and 32 on the basis of a signal from a moving body tracking device 49 as a target monitoring device and irradiating an irradiation target 26 with a charged particle beam; and gate irradiation for controlling the starting and stopping of irradiation of the charged particle beam emitted from an irradiation device 21 on the basis of a signal from the target monitoring device.
摘要翻译：要解决的问题：提供一种能够通过扫描照射方法在粒子照射系统中缩短照射时间（处理时间）并按计划形成剂量分布的带电粒子照射系统和照射规划装置。解决方案：控制系统根据来自作为目标监视装置的移动体跟踪装置49的信号，对照射对象物26照射带电粒子束的扫描电磁体31,32的激励电流值进行照射，以及栅极照射，用于根据来自目标监视装置的信号控制从照射装置21发射的带电粒子束的照射的开始和停止。

8. 发明专利

JP2014054302A Moving body tracking device, and radiation treatment system 有权
标题翻译：移动身体跟踪装置和放射治疗系统
公开(公告)号：JP2014054302A
公开(公告)日：2014-03-27
申请号：JP2012199355
申请日：2012-09-11
申请人： Hitachi Ltd , 株式会社日立製作所 , Hokkaido Univ , 国立大学法人北海道大学
发明人： UMEKAWA TORU , FUJII YUSUKE , NAGAMINE YOSHIHIKO , MIYAMOTO NAOKI , UMEGAKI KIKUO , MATSUURA TAEKO , HIRATA YUICHI , NIHONGI HIDEAKI
IPC分类号： A61N5/10 , A61B6/03
CPC分类号： A61B6/487 , A61N5/1049 , A61N2005/1061
摘要： PROBLEM TO BE SOLVED: To provide a moving body tracking device capable of continuing tracking of targets by setting search regions to proper positions following movement of the targets even when recognition of the targets becomes difficult by a change of an overlapping way between the targets and a structure.SOLUTION: A moving body tracking device calculates two-dimensional positions of a main tracking target 3 and a sub tracking target 4 from captured images of X-ray image capturing devices 5A, 5B by template matching. When it is determined that either one of matching results in the main tracking target 3 and the sub tracking target 4 is insufficient in a search region setting part 15 setting search regions on the basis of results of the matching, the moving body tracking device sets search regions 230, 240 in X-ray-captured images 200 of next frames captured in next timing in the X-ray image capturing devices 5A, 5B by use of the another two-dimensional position, and uses the search regions 230, 240 for search of the main tracking target 3 and the sub tracking target 4 in the next frames.
摘要翻译：要解决的问题：提供一种移动体跟踪装置，其能够通过在目标移动之后将搜索区域设置到适当位置，即使通过改变目标与a的重叠方式的目标变得困难，继续跟踪目标结构。解决方案：移动体跟踪装置通过模板匹配从X射线图像捕获装置5A，5B的捕获图像计算主跟踪目标3和子跟踪目标4的二维位置。当在搜索区域设定部15中确定主追踪对象3和子追踪对象4中的匹配结果中的任一个在根据匹配结果设定搜索区域时不足时，移动体跟踪装置设定搜索在X射线图像捕获装置5A，5B中通过使用另一个二维位置在下一个定时捕获的下一帧的X射线捕获图像200中的区域230,240，并且使用搜索区域230,240进行搜索的主跟踪目标3和子跟踪目标4。

9. 发明专利

JP2012254146A Charged particle beam irradiation system 审中-公开
标题翻译：充电颗粒光束辐射系统
公开(公告)号：JP2012254146A
公开(公告)日：2012-12-27
申请号：JP2011128224
申请日：2011-06-08
申请人： Hitachi Ltd , 株式会社日立製作所 , Hokkaido Univ , 国立大学法人北海道大学
发明人： FUJII YUSUKE , HIRAMOTO KAZUO , NAGAMINE YOSHIHIKO , SHIRATO HIROKI , ISHIKAWA MASAZUMI , UMEGAKI KIKUO
IPC分类号： A61N5/10 , G01T1/161
摘要： PROBLEM TO BE SOLVED: To obtain an accurate PET image in a spot scanning type charged particle beam irradiation system.SOLUTION: A PET control part 49 receives an emission stop signal from an irradiation device control part 48, and starts PET measurement after the lapse of a preset fixed time (S109). When spot irradiation for a spot number j is completed, a spot position corresponding to the spot number j +1 (S111→103) is selected. For the next spot irradiation, the irradiation device control part 48 transmits an emission start signal, and the PET control part 49 stops the PET measurement when receives the emission start signal (S105). In other words, the PET measurement is performed while the emission is stopped. A PET signal obtained in the PET measurement is recorded in a memory in the PET control part 49 as PET data just before the spot irradiation for the spot number j +1. A PET image obtaining function 49a obtains the distribution of positron emitters (the PET image) from the recorded PET data.
摘要翻译：要解决的问题：在点扫描型带电粒子束照射系统中获得精确的PET图像。 PET控制部49从照射装置控制部48接收发光停止信号，经过预定的固定时间后开始PET测定（S109）。当点号j的点照射完成时，选择与点号j + 1（S111→103）相对应的光点位置。对于下一个点照射，照射装置控制部分48发送发射开始信号，并且PET控制部分49在接收到发射开始信号时停止PET测量（S105）。换句话说，在发射停止时进行PET测量。在PET测量中获得的PET信号作为PET数据被记录在PET控制部分49的存储器中，作为点号j +的点照射之前的PET数据。 PET图像获取功能49a从记录的PET数据中获得正电子发射器（PET图像）的分布。版权所有（C）2013，JPO＆INPIT

10. 发明专利

JP2013192702A Radiation treatment controller and radiation treatment control program 有权
标题翻译：辐射处理控制器和辐射处理控制程序
公开(公告)号：JP2013192702A
公开(公告)日：2013-09-30
申请号：JP2012062215
申请日：2012-03-19
申请人： Hokkaido Univ , 国立大学法人北海道大学
发明人： MIYAMOTO NAOKI , SHIMIZU SHINICHI , MATSUURA TAEKO , TORAMATSU CHIE , TAKAO SEISHIN , NIHONGI HIDEAKI , HIRATA YUICHI , UMEGAKI KIKUO
IPC分类号： A61N5/10
CPC分类号： A61N5/1039 , A61B6/022 , A61B6/487 , A61B6/5211 , A61B2090/3966 , A61N5/1037 , A61N5/1049 , A61N2005/1061 , A61N2005/1074
摘要： PROBLEM TO BE SOLVED: To provide a radiation treatment controller and a radiation treatment control program, allowing the calculation of present positions of markers embedded in a patient by a set of radioscopic image radiographing apparatuses, and allowing the reduction of the exposure dose of the patient of radiographing radiation for radioscopy during radiation treatment.SOLUTION: This radiation treatment controller includes: a radioscopic image acquisition part 41 acquiring radioscopic images of three or more markers from a set of radioscopic image radiographing apparatuses 12; a projective line calculation part 38 calculating equations of respective projective lines; an inter-marker distance acquisition part 42 acquiring each distance between the respective markers; a marker position calculation part 43 calculating present positions of the respective markers; and a treating radiation irradiation distinction part 44 distinguishing whether or not to irradiate treating radiation.
摘要翻译：要解决的问题：为了提供一种放射线治疗控制器和放射线治疗控制程序，允许通过一组放射线图像摄影装置计算嵌入在患者体内的标记的当前位置，并且允许减少患者的暴露剂量放射线治疗的放射线检查放射线照射的放射线照射。解决方案：该放射线治疗控制器包括：放射线图像获取部41，从一组放射线图像摄影装置12获取三个以上标记的放射线图像; 投影线计算部38计算各投影线的方程式; 标记间距离获取部分42获取各个标记之间的每个距离; 标记位置计算部43计算各标记的当前位置; 以及区分是否照射治疗射线的治疗放射线照射区别部44。

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