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1. 发明专利

JP5565547B2 Evaluation method of quantitative methods and test substance of damage dna 有权
公开(公告)号：JP5565547B2
公开(公告)日：2014-08-06
申请号：JP2009004976
申请日：2009-01-13
申请人：株式会社マンダム , 国立大学法人金沢大学
发明人：隆一郎倉田 , 一禎大西 , 健一栗山 , 司松永
IPC分类号： G01N33/53 , G01N21/64 , G01N33/48 , G01N33/536

2. 发明专利

JP5300223B2 Evaluation method of expression inhibitor and the test substance 有权
标题翻译：空值
公开(公告)号：JP5300223B2
公开(公告)日：2013-09-25
申请号：JP2007199726
申请日：2007-07-31
申请人：株式会社マンダム
发明人：隆一郎倉田 , 一禎大西 , 健一栗山 , 義雄辻野 , 延規藤原
IPC分类号： A61K36/71 , A61P17/16 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide a means for reducing the phenomena caused by IFN-γ in an individual, a tissue, a cell or the like of an application object and inhibiting the development of the phenomena while suppressing the load on the individual, the tissue, the cell or the like, and to provide a method for evaluating a skin-whitening agent. SOLUTION: The expression inhibitor of the INF-γ-associated factor contains an extract of Moutan Cortex. The method for evaluating the skin-whitening agent comprises evaluating whether the expression of at least one kind of factors selected from the group consisting of CXCR3, IP10, Mig and I-TAC or the expression of the nucleic acid encoding the factor is inhibited or not by the presence of a test material. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种减少应用对象的个体，组织，细胞等中由IFN-γ引起的现象的手段，并且抑制现象的发展，同时抑制对个体，组织，细胞等，并提供评价皮肤美白剂的方法。解决方案：INF-γ相关因子的表达抑制剂含有Moutan Cortex的提取物。用于评价皮肤增白剂的方法包括评价选自由CXCR3，IP10，Mig和I-TAC组成的组中的至少一种因子的表达或编码该因子的核酸的表达是否被抑制通过测试材料的存在。版权所有（C）2009，JPO＆INPIT

3. 发明专利

JP5553660B2 Dna repair accelerator and dna damage inhibitor 有权
公开(公告)号：JP5553660B2
公开(公告)日：2014-07-16
申请号：JP2010077256
申请日：2010-03-30
申请人：株式会社マンダム
发明人：隆一郎倉田 , 郁尚藤田 , 一禎大西 , 健一栗山
IPC分类号： A61K36/18 , A61K8/97 , A61P17/00 , A61P35/00 , A61P43/00 , A61Q19/00
摘要： PROBLEM TO BE SOLVED: To provide a DNA repair accelerator excellent in action of accelerating repair of damaged DNA, and a DNA damage suppressant excellent in action of suppressing production of damaged DNA.SOLUTION: The DNA repair accelerator contains a cinchona extract. The DNA damage suppressant contains at least one chosen from a cinchona extract, a comfrey extract, an arabian coffee extract, a Pueraria root extract, a burdock extract, a Coptis japonica extract, a Sophora angustifolia extract, a chlorella extract, a lavender extract, an Oenothera biennis extract, a rose extract, a Gynostemma pentaphyllum extract, a Rabdosia japonica extract, a Lamium album extract, a carrot extract, a Tilia japonica extract, a great burnet extract, a lotus extract, a tea extract and an Abelmoschus esculentus extract.

4. 发明专利

JP5220791B2 Evaluation method of melanin production-inducing agent and the test substance 有权
公开(公告)号：JP5220791B2
公开(公告)日：2013-06-26
申请号：JP2010074286
申请日：2010-03-29
申请人：株式会社マンダム
发明人：隆一郎倉田 , 郁尚藤田 , 一禎大西 , 健一栗山
IPC分类号： G01N33/50 , A61Q19/02

5. 发明专利

JP4869751B2 San burn cell formation inhibitor and dna damage repair accelerator 有权
标题翻译：空值
公开(公告)号：JP4869751B2
公开(公告)日：2012-02-08
申请号：JP2006069433
申请日：2006-03-14
申请人：株式会社マンダム
发明人：隆一郎倉田 , 一禎大西 , 健一栗山 , 義雄辻野
IPC分类号： A61K8/97 , A61K36/71 , A61P17/16 , A61P43/00 , A61Q17/04
摘要： PROBLEM TO BE SOLVED: To provide a sun burn cell formation inhibitor or DNA damage repair promoter capable of improving the resistance of skin cell itself against the skin trouble caused by ultraviolet light and consisting of a substance having high safety as an active ingredient. SOLUTION: This sun burn cell formation inhibitor or DNA damage repair promoter contains an extract of peony root as an active ingredient. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供能够提高皮肤细胞本身抵抗由紫外线引起的皮肤问题的抗性并由具有高安全性的物质组成的阳光燃烧细胞形成抑制剂或DNA损伤修复促进剂作为活性成分。
解决方案：这种阳光燃烧细胞形成抑制剂或DNA损伤修复促进剂含有牡丹根提取物作为活性成分。版权所有（C）2007，JPO＆INPIT

6. 发明专利

JP5564531B2 Evaluation method of whitening agent 有权
公开(公告)号：JP5564531B2
公开(公告)日：2014-07-30
申请号：JP2012125775
申请日：2012-06-01
申请人：株式会社マンダム
发明人：隆一郎倉田 , 一禎大西 , 健一栗山 , 義雄辻野 , 延規藤原
IPC分类号： G01N33/15 , A61Q19/02 , G01N33/50

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