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    • 1. 发明专利
    • 細胞塊取得装置
    • 细胞质量采集装置
    • JP2015000017A
    • 2015-01-05
    • JP2013125102
    • 2013-06-13
    • 学校法人立命館Ritsumeikan旭光電機株式会社Kyokko Electric Co Ltd
    • KONISHI SATOSHITABATA YASUHIKOWADA TAKASHIHAGIWARA FUMIHIRO
    • C12M1/26C12M1/00C12M3/00
    • 【課題】細胞培養容器において培養した細胞塊を、化学的な標識を行ったり、物理的なダメージを与えたりすることなく、取得することができる細胞塊取得装置の提供。【解決手段】エア射出ノズル11からエアを射出し、エア射出開口111からマイクロウェルMの底面へと向かう液体培地Lの流れa41、マイクロウェルMの底面から通路空間PSへと向かう液体培地Lの流れa43、通路空間PSを上昇する液体培地Lの流れa45、さらに、通路空間PSから上昇した後、下降し、マイクロウェルMの側壁から離れるように、細胞塊受容凹部S133へと向かう液体培地Lの流れa47を形成することができる。マイクロウェルMから剥離された細胞塊Cは、液体培地Lの流れa41、a43、a45、a47に乗って、最終的に、細胞塊受容凹部S133に落下する。これにより、細胞塊Cを細胞塊受容凹部形成部133の細胞塊受容凹部S133によって取得できる。【選択図】図4
    • 要解决的问题:提供能够获取在细胞培养容器中培养的细胞团而不进行化学标记或引起物理损伤的细胞质量获取装置。解决方案:空气从空气喷射喷嘴11喷射,并流动41液体 将从空气喷射口111流向微孔M的底面的培养基L流入从微孔M的底面流向液体培养基L的液体培养基L43流过液体培养物 介质L在通道空间PS中上升,此外,液体培养基L的流动a47流向细胞容量接收凹部S133,以在从通道空间PS升高之后下降,并从侧壁 可以形成微孔M。 从微孔M剥离的细胞质量C最终落入沿着液体培养基L的流动a41,a43,a45,a47移动的细胞容量接收凹部S133中。因此,可以通过 电池容量凹部形成部133的电池容量凹部S133。
    • 2. 发明专利
    • Sample analysis apparatus
    • 样品分析仪
    • JP2014181908A
    • 2014-09-29
    • JP2013054411
    • 2013-03-15
    • Kyokko Electric Co Ltd旭光電機株式会社Ritsumeikan学校法人立命館
    • KONISHI SATOSHIWADA TAKASHIHAGIWARA FUMIHIRO
    • G01N21/27G01N21/03
    • PROBLEM TO BE SOLVED: To provide an inexpensive and small-sized analytical sample-holding device using detection light.SOLUTION: A sample analysis apparatus 100 analyzes blood to be a biological sample held on a biological sample-holding analysis chip C100 by using analysis light. In the sample analysis apparatus 100, a sample is irradiated with analysis light from an LED set 103 and a light quantity of the analysis light transmitted through the sample is detected as an electric signal quantity by using a photodiode 105. Since transmission properties of detection light based on a wavelength are different in accordance with samples, the sample can be analyzed based on a ratio of the electric signal quantity. The analysis light is reflected by a reflection member 107, passed through a substrate 101, and then introduced into the biological sample-holding analysis chip C100. The analysis light passed through the biological sample-holding analysis chip C100 is received by the photodiode 105. Consequently an inexpensive and small-sized analytical sample-holding device can be provided.
    • 要解决的问题:提供一种使用检测光的便宜且小型的分析样品保持装置。解决方案:样品分析装置100通过使用分析光分析作为保持在生物样本保持用分析用芯片C100上的生物样品的血液 。 在样本分析装置100中,利用来自LED组103的分析光照射样品,通过使用光电二极管105将通过样品透射的分析光的光量检测为电信号量。由于检测光的透射特性 基于波长的波长根据样本不同,可以基于电信号量的比率来分析样本。 分析光被反射构件107反射,通过基板101,然后被引入生物样本保持分析芯片C100。 通过生物样本保持分析芯片C100的分析光被光电二极管105接收。因此,可以提供便宜且小型的分析样本保持装置。
    • 3. 发明专利
    • Analysis sample holding apparatus, sample analysis device and method of manufacturing analysis sample holding apparatus
    • 分析样品控制装置,样品分析装置和制造分析样品控制装置的方法
    • JP2012202881A
    • 2012-10-22
    • JP2011068991
    • 2011-03-25
    • Kyokko Denki KkRitsumeikan学校法人立命館旭光電機株式会社
    • KONISHI SATOSHIKOBAYASHI TAIZOWADA TAKASHIHAGIWARA FUMIHIRO
    • G01N21/03G01N21/27
    • PROBLEM TO BE SOLVED: To provide a small-sized analysis sample holding apparatus and sample analysis device suitable for analyzing a predetermined sample in a colorimetric manner.SOLUTION: Analysis light r5 made incident to a diffraction grating G101 is dispersed by the diffraction grating G101 and vertically moves toward an analysis light derivation unit A101 formed on a surface P101 of a first substrate part 101 as dispersed analysis light r6. Thus, since the diffraction grating G101 is disposed inside an organic sample analysis chip, it is not necessary to disperse the analysis light of a predetermined wavelength from white light before flooding the organic sample analysis chip. Furthermore, it is not necessary, either, to prepare a plurality of light sources each emitting analysis light of the predetermined wavelength corresponding to items of analysis. Therefore, the analysis device can be small-sized.
    • 要解决的问题:提供适合于以比色方式分析预定样品的小型分析样品保持装置和样品分析装置。 解决方案:入射到衍射光栅G101的分析光r5被衍射光栅G101分散,并且垂直移向形成在作为分散分析光r6的第一基板部分101的表面P101上的分析光导出单元A101。 因此,由于衍射光栅G101设置在有机样品分析芯片的内部,因此在充满有机样品分析芯片之前不必将预定波长的分析光从白光分散。 此外,也不需要准备多个光源,每个光源发射对应于分析项目的预定波长的分析光。 因此,分析装置可以小型化。 版权所有(C)2013,JPO&INPIT
    • 5. 发明专利
    • Analysis sample holding apparatus and method of manufacturing analysis sample holding apparatus
    • 分析样品控制装置和制造分析样品控制装置的方法
    • JP2012202833A
    • 2012-10-22
    • JP2011067857
    • 2011-03-25
    • Kyokko Denki KkRitsumeikan学校法人立命館旭光電機株式会社
    • KONISHI SATOSHIKOBAYASHI TAIZOWADA TAKASHIHAGIWARA FUMIHIRO
    • G01N21/03
    • PROBLEM TO BE SOLVED: To provide a small-sized and low-priced analysis sample holding apparatus.SOLUTION: A biological sample analysis chip 100 comprises a first substrate part 101 comprised of a transparent polymer resin such as, e.g., polycarbonate and a second substrate part 103. The biological sample analysis chip 100 is formed by joining the first substrate part 101 including a first reflection plane M101 and a second reflection plane M102 and the second substrate part 103 including a third reflection plane M103 and a fourth reflection plane M104. The biological sample analysis chip 100 can be manufactured by a general joint technique using a low-priced resin, thereby manufacturing a low-priced biological sample analysis chip 100. In the biological sample analysis chip 100, analysis light is reflected multiple times inside the biological sample analysis chip 100. Therefore, a length (irreducibly minimum length) capable of absorbing analysis light for the minimum quantity required for colorimetric analysis can be ensured in accordance with a progress length of analysis light r2 to r5 inside a sample holding path R100.
    • 要解决的问题:提供一种小型和低价的分析样品保持装置。 解决方案:生物样品分析芯片100包括由诸如聚碳酸酯的透明聚合物树脂和第二基底部分103组成的第一基底部分101.生物样品分析芯片100通过将第一基底部分 101包括第一反射面M101和第二反射面M102,第二基板部103包括第三反射面M103和第四反射面M104。 生物样品分析用芯片100可以通过使用低价树脂的一般接头技术来制造,从而制造低价生物样品分析芯片100.在生物样品分析芯片100中,生物样品分析芯片100在生物样品分析芯片100内多次反射 因此,可以根据样本保持路径R100内的分析用光r2〜r5的进行长度来确保能够吸收分光用的比色测定分析所需的最小量的长度(不可约束的最小长度)。 版权所有(C)2013,JPO&INPIT
    • 7. 发明专利
    • Long tool and fiber scope
    • 长工具和纤维范围
    • JP2013212258A
    • 2013-10-17
    • JP2012083981
    • 2012-04-02
    • Ritsumeikan学校法人立命館
    • KONISHI SATOSHI
    • A61B1/00G02B23/24
    • PROBLEM TO BE SOLVED: To provide a fiber scope (long tool) in which the flexibility of an insertion portion (soft portion) can be prevented from being deteriorated, compared with conventional ones.SOLUTION: A fiber scope includes: an operation portion 2 to be operated by a user; an insertion portion 3 having a movable portion 5 extending from the operation portion 2 and being operable so as to be bent to a front portion 3a side, and having a deformable soft portion 6 formed on the side from the movable portion 5 to the operation portion 2; and a drive mechanism portion 4 for operating the movable portion 5 so as to be bent. The drive mechanism portion 4 has: an operation wire 11 which operates the movable portion 5 so as to be bent; an air cylinder 12 which is incorporated in the vicinity of the movable portion 5 and pulls the operation wire 11; and a tube 13 which supplies air to the air cylinder 12 and can be deformed by following the soft portion 6. The tube 13 is formed along the soft portion 6 from the air cylinder 12 to the operation portion 2 side.
    • 要解决的问题:提供一种与以往相比可以防止插入部分(软部分)的柔性变差的纤维范围(长工具)。解决方案:一种光纤范围包括:操作部分2至 由用户操作; 插入部分3具有从操作部分2延伸的可移动部分5,并且可操作地弯曲到前部3a侧,并且具有形成在可动部分5的一侧上的可变形的软性部分6到操作部分 2; 以及驱动机构部分4,用于操作可动部分5以弯曲。 驱动机构部分4具有:操作线11,其使可动部分5弯曲; 气缸12,其结合在可动部5附近并拉动操作线11; 以及向气缸12供给空气并且可以通过跟随软部分6而变形的管13.管13沿着柔性部分6从气缸12形成到操作部分2侧。
    • 8. 发明专利
    • Treatment instrument and endoscope using the same
    • 治疗仪器和内窥镜使用相同
    • JP2010187854A
    • 2010-09-02
    • JP2009034272
    • 2009-02-17
    • Ritsumeikan学校法人立命館
    • KONISHI SATOSHIKOBAYASHI DAIZO
    • A61B1/00A61B1/06A61B17/32A61B17/34
    • PROBLEM TO BE SOLVED: To provide a treatment instrument suppressing shade formed on a treatment section and to provide an endoscope using the same.
      SOLUTION: This treatment instrument includes: a surface emission means 5 which has an outgoing surface emitting a light entering from a light source as a planar light, and a treatment section 6 which is formed in the outgoing surface side of the surface emission means 5 for performing a predetermined treatment to biotissue. The outgoing surface 8c for emitting the light as the planar light of a light guide plate 8 is integrally formed with a blade section 10 and an oppression surface 11 of the treatment section 6. This constitution can suppress the shade formed on the treatment section 6 and facilitate the treatment of the biotissue.
      COPYRIGHT: (C)2010,JPO&INPIT
    • 要解决的问题:提供一种抑制形成在处理部分上的色调的治疗仪器,并提供使用其的内窥镜。 解决方案:该治疗仪器包括:表面发射装置5,其具有发射从光源入射的光作为平面光的出射表面;以及处理部分6,其形成在表面发射的出射表面侧 用于对生物组织进行预定处理的装置5。 作为导光板8的平面光而发出光的出射面8c与处理部6的叶片部10和压迫面11一体形成。该结构能够抑制处理部6上形成的阴影, 促进生物组织的治疗。 版权所有(C)2010,JPO&INPIT
    • 9. 发明专利
    • Endoscope system
    • 内窥镜系统
    • JP2009219743A
    • 2009-10-01
    • JP2008069174
    • 2008-03-18
    • Fujinon CorpRitsumeikanShiga Univ Of Medical Scienceフジノン株式会社国立大学法人滋賀医科大学学校法人立命館
    • KONISHI SATOSHITANI TORUKURUMI YOSHIMASAISHIKAWA RYO
    • A61B1/00A61B18/12
    • PROBLEM TO BE SOLVED: To minimize a restriction applied to an observation field of view, to secure a broad observation field of view and to improve the safety and operability of an operation by a high-frequency treatment instrument in mucosal dissection for dissecting a submucosal layer located in the lower part of the incised mucosa.
      SOLUTION: When dissecting mucosa after incising the mucosa with a high-frequency knife 13 of the high-frequency treatment instrument 1, which is inserted in a treatment instrument insertion channel 27 of an insertion section 22 of an endoscope 20, a pressure fluid is supplied to the interior of a flexible bag 33 of a retractor member 31 to curve an elastic plate piece 32 in the direction of separating from the axial center of the insertion section 22 and lift the mucosa.
      COPYRIGHT: (C)2010,JPO&INPIT
    • 要解决的问题:为了最小化对观察视野的限制,确保广泛的观察视野,并且通过高频治疗仪器在粘膜解剖中提高手术的安全性和可操作性,以进行解剖 位于切口粘膜下部的粘膜下层。 解决方案:在用插入到内窥镜20的插入部22的治疗仪器插入通道27中的高频处理器具1的高频刀13切开粘膜之后解剖粘膜时, 流体被供应到牵开器构件31的柔性袋33的内部,以使弹性板件32沿与插入部分22的轴向中心分离的方向弯曲并提起粘膜。 版权所有(C)2010,JPO&INPIT
    • 10. 发明专利
    • Balloon actuator, end-effector and medical implement
    • 气球执行器,终端效应器和医疗执行
    • JP2006204612A
    • 2006-08-10
    • JP2005021730
    • 2005-01-28
    • Ritsumeikan学校法人立命館
    • KONISHI SATOSHITEI GYOKUSAN
    • A61B19/00A61B17/28
    • PROBLEM TO BE SOLVED: To perform operations different from before such as a two-direction operation. SOLUTION: A balloon actuator (5a, 5b, 5c) is provided in which the film body (11, 12) of a surface is expanded while being stretched by the fluid pressure of a fluid supplied to the inside and bending motion is performed by tensile stress generated by the stretch. The film body (11, 12) is provided with: a first film body (11) to be stretched by a fluid pressure; and a second film body (12) constituted so that it is to be stretched by the fluid pressure and the tensile stress generated by the stretch is different from the first film body (11), and joined to the first film body (11) so as to supply the fluid between the first film body (11) and the second film body (12). COPYRIGHT: (C)2006,JPO&NCIPI
    • 要解决的问题:执行与以前不同的操作,例如双向操作。 解决方案:提供一种气囊致动器(5a,5b,5c),其中表面的膜体(11,12)在被供应到内部的流体的流体压力拉伸的同时被膨胀,并且弯曲运动是 由拉伸产生的拉伸应力进行。 薄膜体(11,12)设有:通过流体压力拉伸的第一薄膜体(11); 以及第二膜体(12),其被构造成通过流体压力拉伸并且由拉伸产生的拉伸应力与第一膜体(11)不同,并且与第一膜体(11)接合 以便在第一膜体(11)和第二膜体(12)之间供应流体。 版权所有(C)2006,JPO&NCIPI