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1. 发明专利

JP2009227616A Osteogenesis promoter containing oleuropein and/or hydroxytyrosol as active ingredient 审中-公开
标题翻译：含有作为活性成分的奥昔布宁和/或羟喹诺酮类的促肾上腺皮质激素
公开(公告)号：JP2009227616A
公开(公告)日：2009-10-08
申请号：JP2008075967
申请日：2008-03-24
申请人： Toin Gakuen , Univ Of Tsukuba , 国立大学法人筑波大学 , 学校法人桐蔭学園
发明人： HAGIWARA YOSHIMI , MIYAZAKI HITOSHI
IPC分类号： A61K31/05 , A23L1/30 , A61K31/7048 , A61K36/00 , A61K36/18 , A61P19/08 , A61P19/10 , C07H17/04
摘要： PROBLEM TO BE SOLVED: To provide an osteogenesis accelerator which acts to promote osteogenesis and inhibit bone resorption. SOLUTION: The osteogenesis promoter includes oleuropein and/or hydroxytyrosol as an active ingredient and a pharmaceutical composition includes this osteogenesis promoter as an active ingredient. Further, the oleuropein and/or hydroxytyrosol is used for producing the osteogenesis promoter. Furthermore, a food composition includes oleuropein and designates that it is to be used for improving osteodystrophy and bone metabolic disorders. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：待解决的问题：提供促进成骨并抑制骨吸收的成骨促进剂。骨源性促进剂包括橄榄苷和/或羟基酪醇作为活性成分，并且药物组合物包括该成骨促进剂作为活性成分。此外，使用橄榄精和/或羟基酪醇来生产成骨促进剂。此外，食物组合物包括橄榄苦蛋白，并且表示其用于改善骨营养不良和骨代谢紊乱。版权所有（C）2010，JPO＆INPIT

2. 发明专利

JP2009048946A Dye-sensitized photoelectric conversion element 审中-公开
标题翻译： DYE-SENSITIZED光电转换元件
公开(公告)号：JP2009048946A
公开(公告)日：2009-03-05
申请号：JP2007216282
申请日：2007-08-22
申请人： Teijin Dupont Films Japan Ltd , Toin Gakuen , 学校法人桐蔭学園 , 帝人デュポンフィルム株式会社
发明人： MIYASAKA TSUTOMU , IKEDA NOBUYUKI
IPC分类号： H01M14/00 , H01L31/04
CPC分类号： H01G9/2009 , H01G9/2013 , H01G9/2031 , H01G9/2059 , H01G9/2095 , H01L51/0086 , Y02E10/542
摘要： PROBLEM TO BE SOLVED: To provide an all-solid dye-sensitized photoelectric conversion element having high efficiency based on a dye-sensitized system. SOLUTION: The dye-sensitized photoelectric conversion element has a porous photo-electrode 5 comprising a dye-sensitized porous semiconductor particle layer 3, a charge transport layer, and a facing electrode layer 1 in this order, the charge transport layer is composed of a solid mixture containing 0.1 to 50 wt.% carbon material and 50 to 99.9 wt.% ionic liquid 4 based on the total weight of the carbon material and the ionic liquid 4, and 1 wt.% iodine and 0.9 wt.% p-type conductive polymer are contained or not contained. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供基于染料敏化系统具有高效率的全固体染料敏化光电转换元件。解决方案：染料敏化光电转换元件具有包括染料敏化多孔半导体颗粒层3，电荷传输层和面向电极层1的多孔光电极5，电荷传输层为由含有0.1至50重量％碳材料和50至99.9重量％离子液体4的固体混合物组成，基于碳材料和离子液体4的总重量，以及1重量％的碘和0.9重量％包含或不包含p型导电聚合物。版权所有（C）2009，JPO＆INPIT

3. 发明专利

JP2008303197A Agent for increasing intracellular protoporphyrin ix accumulation amount and composition containing the same for use in photodynamic diagnosis or medical treatment 审中-公开
标题翻译：用于增加细胞内原生质体的累积量IX及其含量的组合物用于光化学诊断或医疗处理
公开(公告)号：JP2008303197A
公开(公告)日：2008-12-18
申请号：JP2007153914
申请日：2007-06-11
申请人： Toin Gakuen , 学校法人桐蔭学園
发明人： TOKUOKA YOSHIICHI , KOSOBE TOSHIYUKI
IPC分类号： A61K41/00 , A61K31/197 , A61K31/198 , A61K31/405 , A61P35/00 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide an agent for increasing intracellular protoporphyrin IX accumulation amount, which can increase the accumulation amount of protoporphyrin IX in diseased tissues safely and simply without increasing the dose of 5-aminolevulinic acid.
SOLUTION: The agent for increasing intracellular protoporphyrin IX accumulation amount comprises an aromatic amino acid as an effective ingredient, in which the aromatic amino acid is at least one selected from phenyl alanine and tryptophan.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供增加细胞内原卟啉IX积累量的试剂，其可以安全且简单地增加患病组织中原卟啉IX的积累量，而不增加5-氨基乙酰丙酸的剂量。解决方案：用于增加细胞内原卟啉IX积累量的试剂包含芳族氨基酸作为有效成分，其中芳族氨基酸是选自苯丙氨酸和色氨酸中的至少一种。版权所有（C）2009，JPO＆INPIT

4. 发明专利

JP2008161478A Shoe and sockliner for the same 审中-公开
标题翻译： SHOE和SOCKLINER相同
公开(公告)号：JP2008161478A
公开(公告)日：2008-07-17
申请号：JP2006354871
申请日：2006-12-28
申请人： Toin Gakuen , Yokohama National Univ , 国立大学法人横浜国立大学 , 学校法人桐蔭学園
发明人： SATSUMOTO YAYOI , TAKEUCHI MASAAKI
IPC分类号： A43B17/08
摘要： PROBLEM TO BE SOLVED: To provide a sockliner for a shoe, capable of effectively promoting a bellows phenomenon by sufficiently discharging air existing in a prescribed part of the shoe, and to provide the shoe.
SOLUTION: The sockliner for the shoe includes: a first air path having an air chamber with two first communicating parts, thereby introducing air from one first communicating part to the air chamber and discharging the introduced air from the other communicating part; and a second air path having an air chamber with two second communicating parts, thereby introducing air from one second communicating part which is arranged closer to the other first communicating part of the first air path than to one air communicating part, and discharging the introduced air from the other second communicating part. The first and second communication paths perform introduction/discharge by a compression operation with respect to the first and second air paths.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种用于鞋的袜子，其能够通过充分排出存在于鞋子的规定部分中的空气并且提供鞋子来有效地促进波纹管现象。解决方案：鞋的鞋垫包括：第一空气路径，具有具有两个第一连通部分的空气室，从而将空气从一个第一连通部分引入到空气室中，并将引入的空气从另一个连通部分排出; 以及第二空气路径，具有具有两个第二连通部的空气室，从而从布置成比第一空气通道的另一个第一连通部更靠近的一个第二连通部引入空气，而不是一个空气连通部从另一个第二通信部分。第一和第二通信路径通过相对于第一和第二空气路径的压缩操作来执行引入/排出。版权所有（C）2008，JPO＆INPIT

5. 发明专利

JP2006341336A ROBOT ARM 审中-公开
公开(公告)号：JP2006341336A
公开(公告)日：2006-12-21
申请号：JP2005168675
申请日：2005-06-08
申请人： TOIN GAKUEN
发明人： KOYANAGI EIJI
IPC分类号： B25J17/00
摘要： PROBLEM TO BE SOLVED: To provide a robot arm, securing a wide rotating angle range in comparatively simple constitution and more easily controlling the rotation. SOLUTION: In this robot arm, the end parts of two arms 1A, 1B are connected to each other to relatively turn along a predetermined plane. A joint part 10 is provided with a sub-arm 2 rotatable with respect to two arms 1A, 1B, and the end parts of two arms 1A, 1B are respectively provided with gears 7, 8, which are meshed with each other. In the thus constructed robot arm, the sub-arm 2 is rotated to the arm 1A by a driving mechanism provided on one arm 1A, thereby rotating the other arm 1B to the arm 1A. COPYRIGHT: (C)2007,JPO&INPIT

6. 发明专利

JP2005160822A Ultrasonic sonde 有权
标题翻译：超声波SONDE
公开(公告)号：JP2005160822A
公开(公告)日：2005-06-23
申请号：JP2003405267
申请日：2003-12-03
申请人： Toin Gakuen , 学校法人桐蔭学園
发明人： TAKEUCHI SHINICHI , SUZUKI TAKAHIRO , KATSURA NAOKI , SATO TOSHIO , KAWASHIMA NORIMICHI , ISHIKAWA MUTSUO , KUROSAWA MINORU , OHIRA ETSUZO
IPC分类号： A61B8/00 , H01L41/083 , H01L41/09 , H04R17/00
摘要： PROBLEM TO BE SOLVED: To provide an ultrasonic sonde with a simple structure in which a piezoelectric element capable of covering up to a high-frequency band is mounted on a small-diameter rod capable of enhancing a spatial resolution to enable the measurement of an ultrasonic sound field.
SOLUTION: In the ultrasonic sonde constituted of an acoustic waveguide composed of an electroconductive rod whose one end is formed on a sound receiving face and which is also used as a ground side electrode, a piezoelectric element film arranged surrounding the electroconductive rod in the vicinity of the end portion opposite to the sound receiving face, and a signal side electrode coming into contact with the surface of the piezoelectric element film arranged insulated from the electroconductive rod, the piezoelectric element is formed by bringing a part consisting of a titanium material to a strong alkaline solution including a piezoelectric element forming component to carry out hydrothermal reaction under a high temperature and a high pressure.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：为了提供一种具有简单结构的超声波探头，其中能够覆盖高频带的压电元件安装在能够提高空间分辨率的小直径杆上以使得能够测量的超声波声场。解决方案：在由导电棒构成的声波导管构成的超声波探头中，导电棒的一端形成在接收面上并且也用作接地侧电极，在导电棒周围布置的压电元件膜与声音接收面相反的端部附近和与导电棒绝缘的压电元件膜的表面接触的信号侧电极，通过使由钛材料构成的部分涉及包含压电元件形成组分的强碱性溶液，以在高温和高压下进行水热反应。版权所有（C）2005，JPO＆NCIPI

7. 发明专利

JP2002273433A METHOD AND DEVICE FOR GENERATING ACTIVE OXYGEN 失效
公开(公告)号：JP2002273433A
公开(公告)日：2002-09-24
申请号：JP2001074708
申请日：2001-03-15
申请人： TOIN GAKUEN
发明人： MORITA KENICHI
IPC分类号： A61L9/015 , B01J19/00 , C01B13/02 , C02F1/46 , C02F1/461 , C02F1/467 , C02F1/50 , C02F1/72 , C25B1/02 , C25B11/06
摘要： PROBLEM TO BE SOLVED: To provide a method which is convenient and efficient and a device which is compact and can be miniaturized, for continuously generating water or air which contains a considerable amount of active oxygen by using a redox polymer having the active oxygen generating activity such as polyaniline. SOLUTION: In this method of generating active oxygen, an anode and a redox polymer-carrying cathode are disposed to face mutually oppositely, a direct current is applied between both electrodes, thereby, the active oxygen is generated from the cathode, therein, the redox polymer-carrying cathode is constituted in such a manner that the plurality of sheets of redox polymer-carrying cathodes are arranged in parallel with a constant interval, at the same time, the interval between an anode plate and each cathode plate is made capable of ionic conductive and the active oxygen is generated by letting oxygen or water pass through gaps between the respective cathodes. This device for generating active oxygen houses the anode plates and modules which consist of the plurality of sheets cathode plates while opposing each other therein, is provided with a mechanism for energizing a box-type case which has a fluid introducing port and a fluid discharging port and the electrodes and, therein, is constituted in such a manner that the cathode plate modules and the plural sheets of redox polymer-carrying cathode plates are arranged in parallel with a prescribed gap.

8. 发明专利

JP2000178208A CONTRAST MEDIUM FOR ULTRASONIC WAVES 失效
公开(公告)号：JP2000178208A
公开(公告)日：2000-06-27
申请号：JP37810998
申请日：1998-12-18
申请人： TOIN GAKUEN
发明人： KAWAN STANT , SATO TOSHIO
IPC分类号： A61K49/00 , A61B8/00
摘要： PROBLEM TO BE SOLVED: To obtain the subject contrast medium for ultrasonic waves that is used for increasing the contrast of the diagnostic images in the ultrasonic water image diagnosis and can be targeted to specific sites in the body by allowing a biotin derivative to statically link to on the surface of specific fine foams. SOLUTION: (B) A biotin derivative is allowed to statically bond to the surfaces of dine foams that are coated with (A) a carboxylate salt. As a carboxylate salt (A), are used sodium laurate, sodium myristate, sodium palmitate, sodium stearate or sodium oleate, singly or in the form of a mixture. In a preferred embodiment, the component (B) is N-(2-aminoethyl)biotin amide hydrochloride represented by the formula.

9. 发明专利

JP2000143550A ULTRASONIC CONTRAST MEDIUM 失效
公开(公告)号：JP2000143550A
公开(公告)日：2000-05-23
申请号：JP35686598
申请日：1998-11-10
申请人： TOIN GAKUEN
发明人： KAWAN STANT , WATARAI HIROSHI , SATO TOSHIO
IPC分类号： A61K49/00
摘要： PROBLEM TO BE SOLVED: To obtain the subject contrast medium capable of manifesting functions to target a specific site in a body by making magnetic substance particles adsorbed onto the surfaces of microbubbles coated with a carboxylic salt. SOLUTION: Magnetic substance particles [preferably γ-Fe2O3, a high Hc type γ-Fe2O3 (Fe3O4), a Co-containing γ-Fe2O3, etc.], are adsorbed onto the surfaces of microbubbles coated with a carboxylic salt (preferably sodium laurate, sodium myristate, sodium palmitate, etc.). The contrast medium is preferably used by coating the magnetic substance particles with a cationic surfactant. The movement of the contrast medium can be controlled by an external magnetic field. Thereby, the microbubbles can timely be introduced into sites causing problems in a human body, e.g. specific regions such as tumors in various kinds of internal organs or early cancers and diseases can accurately be observed and diagnosed by ultrasonic waves.

10. 发明专利

JPH11158675A ACTIVE OXYGEN GENERATOR 失效
公开(公告)号：JPH11158675A
公开(公告)日：1999-06-15
申请号：JP32173097
申请日：1997-11-21
申请人： TOIN GAKUEN
发明人： MORITA KENICHI , KAWASHIMA NORIMICHI
IPC分类号： C02F1/46 , C25B1/30
摘要： PROBLEM TO BE SOLVED: To provide the generator capable of continuously and efficiently generating active oxygen. SOLUTION: An electrode 1 and a grain 2 carrying a redox polymer capable of generating active oxygen on its surface are set in a vessel 3, a feeble current is applied to the electrode 1, and water is introduced into the vessel 3. The oxygen dissolved in the water is brought into contact with the grain 2 and reduced by the redox polymer to generate active oxygen, and the oxidized redox polymer is reduced by receiving the electron from the cathode of the electrode 1. Active oxygen is continuously mass-produced in this way.

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