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    • 1. 发明专利
    • Obesity-preventing agent
    • 防止发烧剂
    • JP2006328056A
    • 2006-12-07
    • JP2006120652
    • 2006-04-25
    • Kinjirushi Kk金印株式会社
    • OKUNISHI ISAONAGAI MASANAITO MICHITAKAFUKUCHI YOSHIKO
    • A61K36/18A23L1/30A61K31/192A61K31/26A61K31/353A61K36/00A61P3/04A61P43/00
    • PROBLEM TO BE SOLVED: To provide an obesity-preventing agent in which in vivo lipid metabolism is improved and accumulated fat is actively decreased and body weight is healthfully decreased. SOLUTION: The obesity-preventing agent comprises a plant body of a cruciferous plant, e.g. Japanese horseradish, preferably a leaf of Japanese horseradish or an extract obtained by carrying out pulverizing treatment and grinding-down treatment of the cruciferous plant, extraction treatment of the cruciferous plant with a solvent and drying treatment of the cruciferous plant alone or in combination thereof as an active ingredient. The obesity-preventing agent improves lipid metabolism and healthfully decreases the fat amount in the body and body weight. COPYRIGHT: (C)2007,JPO&INPIT
    • 待解决的问题:提供体内脂质代谢改善的肥胖症预防剂,积极降低积累的脂肪,并且体重健康地降低。 解决方案:肥胖症预防剂包括十字花科植物的植物体,例如, 日本辣根,优选日本辣根叶或通过进行十字花科植物的粉碎处理和粉碎处理获得的提取物,用溶剂进行十字花科植物的提取处理和单独或组合的十字花科植物的干燥处理作为 活性成分。 肥胖预防剂改善脂质代谢,健康地降低身体和体重中的脂肪量。 版权所有(C)2007,JPO&INPIT
    • 4. 发明专利
    • Method for detecting pungent taste raw material in processed food
    • 检测加工食品中的原料的原料的方法
    • JP2006101722A
    • 2006-04-20
    • JP2004289663
    • 2004-10-01
    • Kinjirushi Kk金印株式会社
    • NAGAI MASAMURATA MITSUYOSHIMINAMI MOTOYASUOISHI YUICHI
    • C12Q1/68A23L27/10
    • PROBLEM TO BE SOLVED: To detect a pungent taste raw material of Eutrema wasabi or Armoracia rusticana contained in a processed food with high precision, by using PCR (polymerase chain reaction) in relatively simple operations. SOLUTION: The method comprises detecting the pungent taste raw material of the Eutrema wasabi or the Armoracia rusticana contained in the processed food based on an electrophoretic pattern of a PCR amplification product, wherein the PCR amplification product is given by using a primer which specifically amplifies only a DNA of the Eutrema wasabi and comprises a sequence derived from a chlorophyll, a primer which specifically amplifies only a DNA of the Armoracia rusticana and comprises a sequence derived from the chlorophyll, or a combination of the primers, so that DNA fragments specific to the pungent taste raw materials are qualitatively detected, respectively. COPYRIGHT: (C)2006,JPO&NCIPI
    • 待解决的问题:通过在相对简单的操作中使用PCR(聚合酶链式反应),以高精度检测加工食品中所含的芥末或芥子油的刺鼻味原料。 解决方案:该方法包括基于PCR扩增产物的电泳图案检测加工食品中所含的Eutrema wasabi或者防锈防锈剂的刺鼻味原料,其中PCR扩增产物通过使用引物 特异性地仅扩增伊曲玛的DNA,并且包含衍生自叶绿素的序列,其仅特异性扩增耐腐蚀的植物DNA的引物,并且包含源于叶绿素的序列或引物的组合,使得DNA片段 分别定性检测出刺鼻味原料的特异性。 版权所有(C)2006,JPO&NCIPI
    • 6. 发明专利
    • Elastase activity inhibitor and cosmetic
    • 弹性酶活性抑制剂和化妆品
    • JP2006008562A
    • 2006-01-12
    • JP2004186463
    • 2004-06-24
    • Kinjirushi Kk金印株式会社
    • OKUNISHI ISAOYAMADA KAZUNOMURATA MITSUYOSHIKOBAYASHI KAZUMITSU
    • A61K36/18A61K8/30A61K8/96A61K31/275A61P17/00A61P43/00
    • PROBLEM TO BE SOLVED: To obtain a cosmetic which inhibits degeneration of elastin by inhibiting the activity of elastase produced and secreted by dermal fibroblasts and exerts an inhibitory action against skin aging. SOLUTION: The elastase activity inhibitor contains an ingredient contained in a cruciferous plant as an active ingredient and inhibits degeneration of elastin by inhibiting the activity of elastase to inhibit skin aging. The ingredient contained in the cruciferous plant is obtained by employing a physical means such as grinding and grating of the cruciferous plant, a solvent extraction means, a drying means or a combination thereof, and its representative example is 6-methylsulfinylhexyl isothiocyanate. COPYRIGHT: (C)2006,JPO&NCIPI
    • 待解决的问题:通过抑制由真皮成纤维细胞产生并分泌的弹性蛋白酶的活性,获得抑制弹性蛋白酶退化的化妆品,并且对皮肤老化起到抑制作用。 解决方案:弹性蛋白酶活性抑制剂含有十字花科植物中含有的成分作为活性成分,通过抑制弹性蛋白酶的活性抑制皮肤老化,抑制弹性蛋白的变性。 通过采用诸如十字花科植物的研磨和格栅等物理手段,溶剂提取装置,干燥装置或其组合来获得十字花科植物中所含的成分,其代表性实例是异硫氰酸6-甲基亚硫酰基己基酯。 版权所有(C)2006,JPO&NCIPI
    • 9. 发明专利
    • Allergic disease-suppressing composition
    • 过敏性疾病抑制组合物
    • JP2009292735A
    • 2009-12-17
    • JP2008144531
    • 2008-06-02
    • Kinjirushi Kk金印株式会社
    • NAGAI MASAICHIKAWA YOSHINOBU
    • A61K31/26A61K8/46A61K8/92A61K47/44A61P11/02A61P11/06A61P17/00A61P27/14A61P37/08A61Q19/00
    • PROBLEM TO BE SOLVED: To provide an allergic disease-suppressing composition that suppresses or mitigates various symptoms of allergic diseases. SOLUTION: The allergic disease-suppressing composition comprises isothiocyanates and a perfume as effective ingredients, where the isothiocyanates are one or more selected from the group consisting of a ω-methylthioalkyl isothiocyanate, a ω-methylsulfinylalkyl isothiocyanate, a ω-methylsulfonylalkyl isothiocyanate and a ω-alkenyl isothiocyanate and the perfume is one or more selected from the group consisting of indoles, ethers, esters, ketones, fatty acids, aliphatic higher alcohols, aliphatic higher aldehydes, aliphatic higher hydrocarbons, thioethers, thiols, terpene hydrocarbons, phenol ethers, phenols, furfurals, aromatic aldehydes, aromatic alcohols, lactones, furans, and natural perfumes. COPYRIGHT: (C)2010,JPO&INPIT
    • 要解决的问题:提供抑制或减轻过敏性疾病的各种症状的过敏性疾病抑制组合物。 过敏性疾病抑制组合物包含异硫氰酸酯和香料作为有效成分,其中异硫氰酸酯是选自ω-甲硫基烷基异硫氰酸酯,ω-甲基亚磺酰基烷基异硫氰酸酯,ω-甲基磺酰基烷基异硫氰酸酯 和ω-链烯基异硫氰酸酯,并且香料是选自吲哚,醚,酯,酮,脂肪酸,脂族高级醇,脂族高级醛,脂族高级烃,硫醚,硫醇,萜烯烃,苯酚中的一种或多种 醚类,酚类,糠醛类,芳香族醛类,芳族醇类,内酯类,呋喃类和天然香料。 版权所有(C)2010,JPO&INPIT
    • 10. 发明专利
    • Method for utilizing isothiocyanate-containing plant
    • 利用含异硫氰酸盐的植物的方法
    • JP2009225698A
    • 2009-10-08
    • JP2008073005
    • 2008-03-21
    • Kinjirushi Kk金印株式会社
    • ICHIKAWA YOSHINOBUNAGAI MASA
    • A23L1/30A61K36/00A61P3/02
    • PROBLEM TO BE SOLVED: To provide a method for utilizing an isothiocyanate-containing plant by which raw material for food or drug medicine stably and highly efficiently containing isothiocyanate is obtained from isothiocyanate-containing plant raw material such as genuine Wasabia japonica, Armoracia rusticana or watercress. SOLUTION: The method for utilizing an isothiocyanate-containing plant includes: crushing the isothiocyanate-containing plant raw material; making the raw material initiate enzymatic reaction so as to generate isothiocyanate; and drying the plant raw material to eliminate moisture therefrom followed by extracting the isothiocyanate with non-aqueous solvent; and utilizing the obtained extract liquid as raw material for food or drug medicine. COPYRIGHT: (C)2010,JPO&INPIT
    • 要解决的问题:提供一种利用含有异硫氰酸酯的植物,其中通过使用含有异硫氰酸酯的植物原料,例如真正的Wasabia japonica,Armoracia获得含有异硫氰酸酯的食品或药物药物的原料, 锈菌或水田芥。 解决方案:利用含异硫氰酸酯的植物的方法包括:粉碎含异硫氰酸酯的植物原料; 使原料引发酶反应,生成异硫氰酸酯; 并干燥植物原料以除去水分,然后用非水溶剂萃取异硫氰酸酯; 利用得到的提取液作为食品或药物的原料。 版权所有(C)2010,JPO&INPIT