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1. 发明专利

JP2009000523A Tubular prosthesis and associated kit 审中-公开
标题翻译：管状预防和相关工具包
公开(公告)号：JP2009000523A
公开(公告)日：2009-01-08
申请号：JP2008160129
申请日：2008-06-19
申请人： Lab Perouse , ラボラトワール・ペルーズ
发明人： STYRC WITOLD
IPC分类号： A61F2/07 , A61F2/848 , A61F2/95
CPC分类号： A61F2/07 , A61F2/848 , A61F2/90 , A61F2002/072 , A61F2002/9511 , A61F2220/0083 , A61F2250/0039
摘要： PROBLEM TO BE SOLVED: To provide a tubular prosthesis capable of attaining highly reliable engagement in the lattice of the tubular prosthesis in a blood vessel. SOLUTION: The tubular prosthesis 100 is radially deformable and comprises a lattice 112 that is deformable between a retracted state of small diameter and an expanded state of larger diameter. The prosthesis 100 comprises at least two outer hooks 118, 119 delimiting between them a clamp 116 for engaging in an outer tissue. The two hooks 118, 119 are carried by the lattice 112 and can be moved between a spaced-apart position in which the clamp 116 is open and a closer-together position in which the clamp 116 is closed. The prosthesis 100 comprises a guiding member 120 for moving at least one of the hooks 118, 119 during deformation of the prosthesis 100. The guiding member 120 delimits a guide passage in which at least one of the hooks 118, 119 is engaged. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：解决的问题：提供能够在血管中实现管状假体的格子的高度可靠接合的管状假体。解决方案：管状假体100是可径向变形的并且包括格子112，其可以在小直径的缩回状态和较大直径的扩张状态之间变形。假体100包括至少两个在它们之间限定的外钩118,119，用于接合外部组织的夹具116。两个钩118,119由格子112承载，并且可以在夹紧件116打开的间隔位置和夹紧件116关闭的更靠近的位置之间移动。假体100包括用于在假体100变形期间移动钩118,119中的至少一个的引导构件120.引导构件120界定引导通道，其中钩118,119中的至少一个接合。版权所有（C）2009，JPO＆INPIT

2. 发明专利

JP2008302230A Kit to be transplanted inside blood circulation vessel 有权
标题翻译：在血液循环中运输的工具包
公开(公告)号：JP2008302230A
公开(公告)日：2008-12-18
申请号：JP2008149817
申请日：2008-06-06
申请人： Lab Perouse , ラボラトワール・ペルーズ
发明人： STYRC MIKOLAJ
IPC分类号： A61F2/24 , A61F2/95
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2002/9534 , A61F2250/006
摘要： PROBLEM TO BE SOLVED: To provide a kit to be transplanted inside a blood circulation vessel which can be inserted in the body of a patient without the diameter of the frame increased in size and can be transplanted to fix a prosthetic valve accurately within the tubular frame previously transplanted.
SOLUTION: The kit 11 comprises a tubular intracorporeal artificial organ 19 having an inner surface 57 determining the Y-Y' directional boundary of a flowing passage 58 and a prosthetic valve 17 to be transplant within the flowing passage 58, the prosthetic valve 17 comprising a supporting frame 25 having an outer surface 31 abutting the inner surface 57 and a flexible shutter 27 connected to the frame 25, wherein the intracorporeal artificial organ 19 comprises stoppers 63, 65 to anchor the supporting frame 25, the stoppers 63, 65 obstructing the outer surface 31 from moving axially along the inner surface 57 at least in the first direction. The stoppers 63, 65 are composed of at least a flexible binding part 69 which is positioned above the inner surface 57 to expand across the flowing passage 58 between two binding points 71 positioned at a certain angle of interval around the longitudinal axis Y-Y'.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种待移植到血液循环容器内的试剂盒，该试剂盒可以插入患者体内，而不需要增加体型尺寸，并可移植，以便将人工瓣膜精确地固定在先前移植的管状框架。解决方案：试剂盒11包括管状体内人造器官19，其具有确定流动通道58的YY方向边界的内表面57和待流动通道58内移植的人工瓣膜17，人造瓣17包括具有与内表面57邻接的外表面31的支撑框架25和连接到框架25的柔性挡板27，其中体内人造器官19包括止动件63,65以锚固支撑框架25，阻挡件63,65阻止外表面31至少沿第一方向沿着内表面57轴向移动。止动件63,65由至少一个位于内表面57上方的柔性装订部分69构成，以在纵向轴线Y-Y'周围以一定角度定位的两个装订点71之间横过流动通道58扩张。。版权所有（C）2009，JPO＆INPIT

3. 发明专利

JP4909265B2 Injection device provided with a pull-out mechanism 有权
公开(公告)号：JP4909265B2
公开(公告)日：2012-04-04
申请号：JP2007512257
申请日：2005-05-02
申请人：ラボラトワール・ペルーズ
发明人：トマヴァルテ、 , エリクペルーズ、
IPC分类号： A61M5/158 , A61M5/32 , A61M25/06 , A61M39/02
CPC分类号： A61M39/0208 , A61M5/158 , A61M5/3243 , A61M25/0612 , A61M2005/1581 , A61M2005/1583 , A61M2209/045

4. 发明专利

JP2009006142A Treatment of implantable medical device resistant to calcification 有权
标题翻译：针对计算的可植入医疗器械的治疗
公开(公告)号：JP2009006142A
公开(公告)日：2009-01-15
申请号：JP2008160002
申请日：2008-06-19
申请人： Lab Perouse , ラボラトワール・ペルーズ
发明人： SHEN MING
IPC分类号： A61F2/24 , A61L27/00
CPC分类号： A61L27/22 , A61L27/3604 , A61L27/3625 , A61L27/3641 , A61L27/3645 , A61L27/3687 , Y02P20/582
摘要： PROBLEM TO BE SOLVED: To provide a protein-based implant having biocompatibility, restraining calcification to a degree enough to avoid periodic replacement of implant. SOLUTION: This method for treating an implant having a protein-based substrate includes: (A) a process of treating the protein-based substrate with a compound containing at least one aldehyde group; then (B) a process of treating the substrate with a compound containing a borohydride; and then (C) a process of treating the substrate resulting from the process (B) with a derivative containing a silane group. The invention also relates to the treated protein-based implant obtained as the result of this method. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：为了提供具有生物相容性的基于蛋白质的植入物，将钙化抑制到足以避免植入物的周期性更换。解决方案：用于处理具有蛋白质底物的植入物的方法包括：（A）使用含有至少一个醛基的化合物处理蛋白质基底物的方法; 然后（B）用含有硼氢化物的化合物处理底物的方法; 然后（C）用含有硅烷基团的衍生物处理由方法（B）得到的基材的方法。本发明还涉及作为该方法的结果获得的经处理的基于蛋白质的植入物。版权所有（C）2009，JPO＆INPIT

5. 发明专利

JP2007007442A Expansible endoprosthesis for treating human or animal tubular organ, and fitting tool for use thereof 审中-公开
标题翻译：用于治疗人或动物管状体的可扩展的内源性物质及其使用的接头工具
公开(公告)号：JP2007007442A
公开(公告)日：2007-01-18
申请号：JP2006246637
申请日：2006-09-12
申请人： Lab Perouse Implant , ラボラトワールペルーズエプラ
发明人： RICHARD THIERRY , PEROUSE ERIC
IPC分类号： A61F2/00 , A61F2/90 , A61F2/95 , A61F2/97
CPC分类号： A61F2/90 , A61F2/95 , A61F2/97 , A61F2002/3008 , A61F2002/30199 , A61F2002/30327 , A61F2230/0063 , A61F2230/0078 , A61F2250/0039 , A61F2250/0098
摘要： PROBLEM TO BE SOLVED: To provide an expansible endoprosthesis capable of preventing a muscular tissue from entering a gap of a net shape material so as to not only make a trauma but generate a turbulent flow in a blood stream.
SOLUTION: The endoprosthesis includes an extensible tubular mesh covered with a plastic or elastomer extensible film. A tool for positioning the endoprosthesis includes a tulip-shaped housing 4 and a tube-shaped guide 8 provided at its distal end of the same. Cutting threads cause the housing 4 to open longitudinally into several petal-like parts. The endoprosthesis is sutable to endoluminal treatment of aneurisms and dilations for a medical use.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供能够防止肌肉组织进入网状材料的间隙的可膨胀内用假体，以便不仅造成创伤，而且在血流中产生湍流。解决方案：内用假体包括用塑料或弹性体可延展膜覆盖的可伸缩管状网。用于定位内置假体的工具包括郁金香形壳体4和设置在其前端的管状引导件8。切割螺纹使得壳体4纵向打开成几个花瓣状部件。内置假体适用于腔内治疗动脉瘤和扩张用于医疗用途。版权所有（C）2007，JPO＆INPIT

6. 发明专利

JP2010508109A A method of manufacturing an implantable prosthesis from the base element made of porous material, the prosthesis on it, and, use the 审中-公开
公开(公告)号：JP2010508109A
公开(公告)日：2010-03-18
申请号：JP2009535104
申请日：2007-11-05
申请人：ラボラトワール・ペルーズ
发明人：バシャリ，エヴァ , モンド，ヨハンネ , ワルター，トマ
IPC分类号： A61L27/00 , A61F2/06 , A61L29/00
CPC分类号： A61L27/54 , A61K9/0024 , A61L27/34 , A61L27/56 , A61L31/10 , A61L31/14 , A61L31/16 , A61L2300/802 , C08K3/32 , C08K5/092 , C08L5/16 , C08L33/02 , C09D105/16 , C09D133/02 , C08L2666/04
摘要：本発明は、多孔質材製のベースエレメントから埋め込み型プロテーゼを製造する方法、それに関するプロテーゼ、および、その使用に関する。本発明の方法は、コーティング（１４）を本体（１２）に施す工程（５０）を含み、ここで、このコーティングは、シクロデキストリン、および／または、シクロデキストリン誘導体、および／または、シクロデキストリン包接錯体、または、ポリカルボン酸、および、触媒を含む生物活性剤を受容する。この方法は、本体（１２）を、１００℃〜２２０℃の温度で１〜９０分間加熱する工程（５８）と、それに続く、本体（１２）を水中で洗浄し乾燥する工程とを含む。また、この方法は、本体を、少なくとも１の生物活性剤の濃縮液に含浸させる任意の連続する工程を含み得る。乾燥工程の後に、本体（１２）に密封コーティングを設け、その後、本体（１２）が内部の密封液体循環チャンネルを規定する。

7. 发明专利

JP2007536045A Injection device provided with a pull-out mechanism 有权
公开(公告)号：JP2007536045A
公开(公告)日：2007-12-13
申请号：JP2007512257
申请日：2005-05-02
申请人：ラボラトワール・ペルーズ
发明人：トマヴァルテ、 , エリクペルーズ、
IPC分类号： A61M5/158 , A61M5/32 , A61M25/06 , A61M37/00 , A61M39/02
CPC分类号： A61M39/0208 , A61M5/158 , A61M5/3243 , A61M25/0612 , A61M2005/1581 , A61M2005/1583 , A61M2209/045
摘要：注射装置（１０）は、針サポート（２４）と、針サポート（２４）に固定され、針サポート（２４）と間隔を空けて配置された自由端（２８）を有する注射針（２２）と、ベース（５２）と、針（２２）の使用位置と引き抜き位置との間をベース（５２）に対して移動可能な押し部材（５４）と、を有する、注射針（２２）の引き抜き機構（５０）と、を有する。ベース（５２）は針サポート（２４）に固定され、引き抜き機構（５０）の非作動位置と作動位置との間を針サポート（２４）に対して相対移動可能である。薬剤の投与分の注射に用いられる。

8. 发明专利

JP5265253B2 Processing of the implantable medical device resistant to calcification 有权
公开(公告)号：JP5265253B2
公开(公告)日：2013-08-14
申请号：JP2008160002
申请日：2008-06-19
申请人：ラボラトワール・ペルーズ
发明人：ミン・シェン
IPC分类号： A61F2/24 , A61L27/00
CPC分类号： A61L27/22 , A61L27/3604 , A61L27/3625 , A61L27/3641 , A61L27/3645 , A61L27/3687 , Y02P20/582
摘要： Treating an implant comprising protein-based substrate involves (A) treating protein-based substrate with a compound containing at least one aldehyde group; (B) treating substrate with a compound containing a borohydride; and (C) treating substrate with a derivative containing a silane group.

9. 发明专利

JP4476296B2 Tubular prosthesis 有权
公开(公告)号：JP4476296B2
公开(公告)日：2010-06-09
申请号：JP2006552659
申请日：2005-02-09
申请人：ラボラトワール・ペルーズ
发明人：ペルース，エリック
IPC分类号： A61F2/07 , A61F2/848 , A61F2/90 , A61F2/95
CPC分类号： A61F2/07 , A61F2/848 , A61F2/90 , A61F2/95 , A61F2002/072 , A61F2002/8486 , A61F2002/9511 , A61F2220/0008 , A61F2220/0016 , A61F2230/0013 , A61F2230/0054
摘要： The prosthesis has a metallic lattice (12) deformable between a retracted state of reduced diameter and a dilated state of larger diameter, and three clamps (16) regularly and angularly distributed at its periphery. Each clamp has two hooks (18) carried by the lattice. The hooks are movable with respect to each other between a deployed position, in which the clamp is opened and a closure position, in which the clamp is closed. - An INDEPENDENT CLAIM is also included for a blood vessel treatment kit comprising a tubular prosthesis.

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