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71. 发明专利

JP2005500031A Apparatus and method for pre-treating the sperm 审中-公开
公开(公告)号：JP2005500031A
公开(公告)日：2005-01-06
申请号：JP2003504846
申请日：2002-06-18
申请人：ファーティリティ・メディカル・イクイップメント・(スコットランド)・リミテッドFertility Medical Equipment (Scotland) Ltd
发明人：ファルハング・アベド
IPC分类号： A01K67/02 , A61B17/425 , A61B17/43 , C12M1/24 , C12N5/06
CPC分类号： A61B17/43
摘要：精子を含む精液サンプルから運動精子を分離するためのデバイス（１２）は、内部に狭窄部（２０）を備えた管状の導管（１４）を含む。狭窄部は、そこを通過する流体の毛細管流を生成するような寸法にされる。サンプルは、精液を同伴して狭窄部を通過する流体培地とともに、より大きい断面積を有するデバイスの上流側端部（１６）に入れられる。運動精子は、狭窄部を通過して、流れに逆らって泳ぎ、導管の遠位端部の採取ゾーンで収集され、この採取ゾーンからそれらは吸引され得る。非運動精子は、デバイスから流出させられる。

72. 发明专利

JP3588303B2 Vitrification tool and method of the egg or embryo 有权
公开(公告)号：JP3588303B2
公开(公告)日：2004-11-10
申请号：JP2000069862
申请日：2000-03-14
申请人：兵庫県
发明人：由佳子 ▲はま▼田 , 敬一郎冨永
IPC分类号： A01K67/02 , A61B17/42 , A61B17/425 , A61B17/43 , A61D19/00 , A61J3/00

73. 发明专利

JP2001252293A TOOL AND METHOD FOR VITRIFYING OVUM OR EMBRYO 失效
公开(公告)号：JP2001252293A
公开(公告)日：2001-09-18
申请号：JP2000069862
申请日：2000-03-14
申请人： HYOGO PREFECTURE
发明人： TOMINAGA KEIICHIRO , HAMADA YUKAKO
IPC分类号： A01K67/02 , A61B17/42 , A61B17/425 , A61B17/43 , A61D19/00 , A61J3/00
摘要： PROBLEM TO BE SOLVED: To provide a method and tool for simply vitrifying an ovum or embryo of a mammal at an ultrahigh speed to stably achieve a high survival rate. SOLUTION: The tool for vitrifying an ovum or an embryo includes a cylindrical extremely fine pipe part 1 and the connection part continued to the extremely fine pipe part to be mounted on a suction and discharge instrument. Since the shortest distance between two points opposed to each other at the cavity part having a vertical cross section with respect in the longitudinal direction of the extremely fine pipe part is shorter than the twice of the minimum outer diameter of the ovum or embryo and longer than the maximum diameter thereof, it prevented that two or more OVUM or embryos enter the extremely fine pipe part to be arranged on the surface vertical to the extremely fine pipe part in the longitudinal direction.

74. 发明专利

JP2001190560A OVUM COLLECTION NEEDLE AND WASHING AND ABSORBING OVUM COLLECTION DEVICE USING THE SAME 失效
公开(公告)号：JP2001190560A
公开(公告)日：2001-07-17
申请号：JP2000001278
申请日：2000-01-07
申请人： NIPRO CORP
发明人： HIEJIMA NORIHIRO
IPC分类号： A61B17/42 , A61B17/425 , A61B17/43 , A61D19/00 , A61M25/00
摘要： PROBLEM TO BE SOLVED: To provide can ovum collection needle capable of ensuring an inside diameter of an ovum collection route to a size allowing an ovum to pass and ensuring a flow rate of a washing route sufficiently and provide a washing and absorbing ovum collection device using the ovum sampling needle. SOLUTION: This ovum collection needle comprises an outer needle 1 made of synthetic resin, a rigid inner needle 2 which is inserted and fitted in the outer needle 1 and is provided with a blade tip 22 at its tip, and a branched connector 3 fixing terminal parts of the outer needle 1 and the inner needle 2, respectively. A restriction part 12 adhering on a tip part of the inner needle 2 closely is formed in a tip part of the outer needle 1, and a groove 23 in the longitudinal direction for flowing washing liquid is provided on an outer surface of the inner needle 2 corresponding to the restriction part 12.

75. 发明专利

JPH10512468A 失效
公开(公告)号：JPH10512468A
公开(公告)日：1998-12-02
申请号：JP52225296
申请日：1995-12-08
IPC分类号： A61M25/00 , A61B17/425 , A61M25/01 , A61B17/43

76. 发明专利

JPH08502035A 失效
公开(公告)号：JPH08502035A
公开(公告)日：1996-03-05
申请号：JP50391294
申请日：1993-07-09
IPC分类号： A61B17/425 , A61K31/715 , A61K35/16 , A61K38/00 , A61K38/46 , A61K38/55 , A61L27/22 , A61P13/02 , A61P15/00 , A61B17/43 , A61K31/725

77. 发明专利

JPH082360B2 失效
公开(公告)号：JPH082360B2
公开(公告)日：1996-01-17
申请号：JP50592786
申请日：1986-11-07
申请人： RANOUX CLAUDE
发明人： RANOUX CLAUDE
IPC分类号： A61B17/42 , A61B17/425 , A61B17/435 , A61B19/02 , A61H1/00 , C12M1/00 , A61B17/43
摘要： PCT No. PCT/FR86/00378 Sec. 371 Date Jul. 6, 1987 Sec. 102(e) Date Jul. 6, 1987 PCT Filed Nov. 7, 1986 PCT Pub. No. WO87/02879 PCT Pub. Date May 21, 1987.The invention relates to a container for fertilization of human ovocytes in the absence of CO2 which may be done in an incubuator at 37 DEG C. or in the vaginal cavity. The container of cylindrical shape has smooth and rounded walls 1 whose thickness is 2 mm in the body 2 of the cylinder but only 1 mm at the neck 3. On the outer wall of the neck is seen a screwthread 4 permitting external screwing on of the plug 12 whose sides are smooth and rounded. The blind end 5 of the container is rounded, the other 6 is flat and has a round orifice 7, which orifice is closed by a fine membrane 9 permitting hermeticity of the tube in order to avoid disorders of the culture medium 8 present in the container as of manufacture. Above the liquid remains about 200 mu l of gas 10. The inner walls 11 are smooth and rounded. After depositing the ovocytes and spermatozoa necessary for fertilization, and therefore after rupture of the membrane, hermeticity will be effected by two seals, after screwing on the plug, a circular one 13 at the neck of the tube, the other 14 on the endwall of the plug which will be flattened against the orifice of the tube 7 by a relief portion, located on the endwall of the plug 15, whose diameter is substantially that of the orifice. The container will be held in the posterior fornix of the vaginal cavity by a flexible ring comprised of a metal strip 17 sheathed in rubber 18 to which is fixed a rubber pouch 19 in which the container is placed. This device thus permits inter-vaginal, fertilization of human ovocytes in the absence of CO2-enriched air, the vaginal cavity replacing the incubator conventionally used.

78. 发明专利

JPH06178634A METHOD FOR SCREENING GOOD SPERM 失效
公开(公告)号：JPH06178634A
公开(公告)日：1994-06-28
申请号：JP33298292
申请日：1992-12-14
申请人： JINNO MASAO
发明人： JINNO MASAO
IPC分类号： A01K67/02 , A61B17/425 , A61B17/43 , A61K35/52 , B01D15/00 , G01N33/50
摘要： PURPOSE:To screen the good sperm by passing a sperm suspension through a PSA-affinitive glass bead column container and allow glass beads to adsorb the sperm having intact acrosome thereon. CONSTITUTION:Glass wool is spread on the bottom of a vertical container, and washed glass beans are charged in the container. A phosphoric acid buffer solution containing PSA in a concentration of 0.1-1mg/ml is filled in the container and subsequently allowed to stand at 4 deg.C for 3-21 days. A sperm suspension is passed through the obtained PSA-affinitive glass bead column container, and allowed to stand for approximately 15min at room temperature to adsorb sperms having intact acrosome. Non-adsorbed sperms are eluted with a phosphoric acid buffer solution, and subsequently a phosphoric acid buffer solution containing mannose is poured to the container at room temperature for 10min to release the adsorbed sperms for their recovery.

79. 实用新型

JPH0349703Y2 失效
公开(公告)号：JPH0349703Y2
公开(公告)日：1991-10-23
申请号：JP9567988
申请日：1988-07-21
IPC分类号： A61M25/00 , A61B17/425 , A61B17/43 , A61M37/02

80. 发明专利

JPH0199572A INJECTION CATHETER FOR ARTIFICIAL INSEMINATION 失效
公开(公告)号：JPH0199572A
公开(公告)日：1989-04-18
申请号：JP25630587
申请日：1987-10-13
申请人： KITASATO SUPPLY KK
发明人： INOUE TAMOTSU
IPC分类号： A61B17/425 , A61B17/43 , A61M25/00
摘要： PURPOSE:To surely suck high-concentration semen without block with vaginal foreign substances at the time of insertion, by stopping the tip of a catheter tube, and by providing only the cross-sectional unilateral region on the tip side with a side hole communicating with the inside and outside of the tube. CONSTITUTION:After the catheter tube 12 of a catheter 10 is inserted gradually from vaginal 16 into the opening of uterus 17, semen is slowly injected into intrauterine cavity 18. Since the tip of the catheter tube 12 is not open, vaginal foreign substances are prevented from invading into the catheter tube 12 or from adhering to side hole 13, resulting in no block of the semen injection path of the catheter tube 12. When a small volume of semen present on the bottom of a test tube set in inclivation is to be sucked into syringe barrel 11, turning the catheter tube 12 with side hole 13 downward to the bottom of the test tube allows suction of the whole semen. As a result, high-concentration semen can surely be sucked.

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