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71. 发明专利

JP5692487B2 エポキシ化合物組成物有权
标题翻译：环氧化合物的组合物
公开(公告)号：JP5692487B2
公开(公告)日：2015-04-01
申请号：JP2009537030
申请日：2008-10-03
申请人：株式会社伏見製薬所
发明人：多田祐二 , 池田憲明 , 守屋成真 , 内海圭一郎 , 小山重人 , 鈴木敦子
IPC分类号： C08L101/00 , C08L63/00 , C08G59/14
CPC分类号： C08G59/1488 , C08L63/00 , H05K1/0326

72. 发明专利

JP5531363B2 1,5-d- anhydroglucitol method of separation 有权
公开(公告)号：JP5531363B2
公开(公告)日：2014-06-25
申请号：JP2010141648
申请日：2010-06-22
申请人：国立大学法人富山大学 , 株式会社伏見製薬所
发明人：敦加藤 , 圭竹下 , 文博石川
IPC分类号： G01N30/46 , B01D15/00 , B01D15/08 , B01J39/04 , C12P7/04 , G01N30/26 , G01N30/88
摘要： PROBLEM TO BE SOLVED: To provide a separation method of 1,5-AG, capable of separately collecting 1,5-AG with high purity at a high collecting rate.SOLUTION: A method separates 1,5-AG from a liquid concentrate containing sugar including 1,5-AG with eluent water using a chromatographic separation apparatus. The liquid concentrate has a sugar concentration of equal to or more than 20 wt.%. The chromatographic separation apparatus comprises a circulation system composed of serially and endlessly connected packed towers filled with a strong acid ion exchange resin or an immobilizing enzyme, a liquid concentrate supply part and an eluent supply part to the circulation system, and a discharge part of a 1,5-AG fraction and a discharge part of a sugar fraction other than 1,5-AG from the circulation system. The respective supply parts and the respective discharge parts are arranged in a specific sequence in the circulation system and sequentially moved in a specific direction while keeping the same positional relationship among them, so that separation is performed while four zones formed in the circulation system are moving.

73. 发明专利

JP2014051634A Method for producing polyurethane open-cell porous material, polyurethane open-cell porous material and swab 有权
标题翻译：聚氨酯开环多孔材料的生产方法，聚氨酯开孔多孔材料和SWAB
公开(公告)号：JP2014051634A
公开(公告)日：2014-03-20
申请号：JP2012198601
申请日：2012-09-10
申请人： Fushimi Pharm Co Ltd , 株式会社伏見製薬所
发明人： UYAMA HIROSHI , SHAN JINYU , ITO YOSHIAKI , KUWANO TOMOMASA
IPC分类号： C08J9/26
摘要： PROBLEM TO BE SOLVED: To provide a method for producing a polyurethane open-cell porous material in which the porous material mainly composed of fine cells and excellent in liquid-absorbing property can be produced without use of a cell-generating agent, a polyurethane open-cell porous material which can be produced by this method, has fine cells and is excellent in liquid-absorbing property, and a swab using the polyurethane open-cell porous material.SOLUTION: A method for producing a polyurethane open-cell porous material comprises the steps of: dissolving a resin comprising polyurethane as a main component in a mixed solvent comprising water, a polyurethane-dissolving organic solvent A, and a polyurethane-swelling organic solvent B to obtain a polyurethane solution; cooling the polyurethane solution to precipitate a polyurethane molded body in the mixed solvent; and removing the mixed solvent from the polyurethane molded body. A polyurethane open-cell porous material which can be produced by this method, has fine cells and is excellent in liquid-absorbing property and a swab using the polyurethane open-cell porous material are also provided.
摘要翻译：要解决的问题：提供一种聚氨酯开孔多孔材料的制造方法，其中可以在不使用细胞发生剂的情况下生产主要由细胞组成的多孔材料和具有优异的液体吸收性的多孔材料，聚氨酯开口可以通过该方法制造的细胞多孔材料具有细小的细胞并且具有优异的液体吸收性，以及使用聚氨酯开孔多孔材料的棉签。解决方案：一种生产聚氨酯开孔多孔材料的方法包括将包含聚氨酯作为主要成分的树脂溶解在包含水，聚氨酯溶解性有机溶剂A和聚氨酯溶胀有机溶剂B的混合溶剂中以获得聚氨酯溶液的步骤; 冷却聚氨酯溶液使聚氨酯成型体在混合溶剂中沉淀; 并从聚氨酯成型体中除去混合溶剂。通过该方法制造的聚氨酯开孔多孔材料也具有细孔，液体吸收性优异，使用了聚氨酯开孔多孔质的棉签也被提供。

74. 发明专利

JP5330976B2 Pharmaceutical composition comprising, as an active ingredient a D- allose 有权
公开(公告)号：JP5330976B2
公开(公告)日：2013-10-30
申请号：JP2009277930
申请日：2009-12-07
申请人：株式会社伏見製薬所 , 国立大学法人香川大学 , 株式会社林原
发明人：健何森 , 雅明徳田 , 俊文板野 , 修宮本 , 俊彦石田 , 孝児村尾 , 大象田坂 , 巌宗内 , 文徳山口 , 輝和田中 , モハマドアクラムホセイン , 正明植木 , 一行廣岡 , 朝彦田港 , 桂二津▲崎▼ , 武雄高橋 , 充宏永田 , 豊石田
IPC分类号： A61K31/7004 , A23L1/09 , A23L1/30 , A61K8/60 , A61P1/16 , A61P9/10 , A61P13/12 , A61P17/00 , A61P25/00 , A61P27/02 , A61P35/00 , A61Q19/00 , C12N5/08
CPC分类号： A61Q19/00 , A23L29/30 , A23L33/10 , A61K8/60 , A61K31/7004
摘要： A method of utilizing the physiological activity of a rare saccharide, wherein physiological-activity sensitive cells are treated with the rare saccharide to modify the function of the cells. A composition containing, as an active ingredient, a rare saccharide which is introduced into physiological-activity sensitive cells and has an effect of modifying the function of the cells. The cells are human cells. The composition is a functional food, a drug, or a cosmetic. The rare saccharide is a rare saccharide belonging to aldose and/or ketose. The aldose is D-allose, and the cells are selected from the group consisting of cancer-cell proliferation inhibitory activity sensitive cells and active-oxygen production inhibitory activity sensitive cells. The ketose is D-psicose, and the cells are selected from the group consisting of chemokine secretion inhibitory activity sensitive cells, microglia migration inhibitory activity sensitive cells, and hypoglycemic activity sensitive cells.

75. 发明专利

JP5190910B2 Cyanato group-containing cyclic phosphinate compounds and methods of manufacturing the 有权
公开(公告)号：JP5190910B2
公开(公告)日：2013-04-24
申请号：JP2006268643
申请日：2006-09-29
申请人：株式会社伏見製薬所
发明人：祐二多田 , 卓思井上 , 成真守屋
IPC分类号： C08K5/5313 , C07F9/6574 , C08L101/00

76. 发明专利

JP2012232927A Oligo(phenyleneoxy) group-containing cyclic phosphazene compound modified with cyanate group, and production method of the same 有权
标题翻译：含有氰基的OLIGO（苯乙烯）基团的环状磷酸酯化合物及其制备方法
公开(公告)号：JP2012232927A
公开(公告)日：2012-11-29
申请号：JP2011102550
申请日：2011-04-29
申请人： Fushimi Pharm Co Ltd , 株式会社伏見製薬所
发明人： MORIYA NARIMASA , KAGAWA MASAMI , FUSHIMI TOSHITAKE , UTSUMI KEIICHIRO , IKEDA NORIAKI , KANAZAWA MAKOTO , TADA YUJI
IPC分类号： C07F9/6593 , C08G65/48 , C08K5/5399 , C08L71/12 , C08L101/00
摘要： PROBLEM TO BE SOLVED: To provide a cyclic phosphazene compound that increases flame retardancy and dielectric characteristics of a resin molded body without decreasing high-temperature reliability and mechanical characteristics.SOLUTION: An oligo(phenyleneoxy) group-containing cyclic phosphazene compound modified with a cyanate group is provided, which is expressed by formula (1). In formula (1), n represents an integer of 1 to 6; in a plurality of A, at least one A represents a phenyleneoxy group expressed by formula (3) and others represent an aryloxy group. In formula (3), q represents an integer of 1 to 50; and Eto Erepresent a hydrogen atom, an alkyl group or the like.
摘要翻译：要解决的问题：提供增加树脂成型体的阻燃性和介电特性的环状磷腈化合物，而不降低高温可靠性和机械特性。解决方案：提供用氰酸酯基改性的含低级（亚苯基氧基）基团的环磷腈化合物，其由式（1）表示。在式（1）中，n表示1〜6的整数，在多个A中，至少一个A表示由式（3）表示的苯撑氧基，其余的表示芳氧基。式（3）中，q表示1〜50的整数， E 6 表示氢原子，烷基等。版权所有（C）2013，JPO＆INPIT

77. 发明专利

JPWO2010106871A1 浸透圧調整剤审中-公开
公开(公告)号：JPWO2010106871A1
公开(公告)日：2012-09-20
申请号：JP2011504786
申请日：2010-02-19
申请人：国立大学法人富山大学 , 株式会社伏見製薬所
发明人：敦加藤 , 敦加藤 , 圭竹下 , 圭竹下 , 文博石川 , 文博石川
IPC分类号： A61K31/351 , A61K9/08 , A61K31/7004 , A61K47/10 , A61M1/14 , A61M1/28 , A61P7/08 , A61P13/12 , A61P27/02
CPC分类号： B01D61/243
摘要：式(I)で表わされる1,5-D-アンヒドログルシトールを含有してなる浸透圧調整剤、ならびに該調整剤を含有する腹膜透析液、眼科用組成物、及び輸液剤。本発明の浸透圧調整剤は、生体適合性に優れ、安全性に問題がなく、かつ、生体内の蓄積性がないため、腹膜透析液、眼科用組成物、輸液剤等の浸透圧調整を要する組成物に、好適に使用することができる。また、本発明の浸透圧調整剤は、他の成分と反応したり、分解したりすることもなく安定な物質であるため、該調整剤を含有する腹膜透析液、眼科用組成物、及び輸液剤は、使用直前に他の成分と配合するというような製剤学的な工夫を要しない形態をとることができる。

78. 发明专利

JP2012116842A Cyclic phosphazene compound 有权
标题翻译：环磷酸酯化合物
公开(公告)号：JP2012116842A
公开(公告)日：2012-06-21
申请号：JP2012001703
申请日：2012-01-07
申请人： Fushimi Pharm Co Ltd , 株式会社伏見製薬所
发明人： INOUE TAKASHI , KANAZAWA MAKOTO , UCHIDA TADASHI
IPC分类号： C07F9/6581 , C08G79/02 , C09K21/12
CPC分类号： Y02P20/55
摘要： PROBLEM TO BE SOLVED: To provide a cyclic phosphazene compound useful as an intermediate for producing another cyclic phosphazene compound having a reactive group such as an alkenyloxy group and an acryloyloxy group.SOLUTION: The phosphazene compound is represented by formula (15) (where n denotes an integer from 3 to 15). An example of Q is a substituted phenyloxy group represented by formula (7), where Zrepresents a protecting group formable of an OH group when it is eliminated.
摘要翻译：待解决的问题：提供可用作中间体的环状磷腈化合物，用于制备具有反应性基团如烯氧基和丙烯酰氧基的另一种环状磷腈化合物。解决方案：磷腈化合物由式（15）表示（其中n表示3至15的整数）。 Q的实例是由式（7）表示的取代的苯氧基，其中Z 1表示当除去OH基时可形成的保护基。版权所有（C）2012，JPO＆INPIT

79. 发明专利

JP4945364B2 Method for separating sugar alcohol 有权
公开(公告)号：JP4945364B2
公开(公告)日：2012-06-06
申请号：JP2007198924
申请日：2007-07-31
申请人：オルガノ株式会社 , 株式会社伏見製薬所
发明人：吉野　　彰 , 響介山田 , 圭竹下
IPC分类号： G01N30/88 , G01N30/26 , G01N30/46
摘要： PROBLEM TO BE SOLVED: To provide a method for separating solutions, respectively containing rare sugar alcohols of high purity in a high recovery ratio from a raw solution containing two kinds of sugar alcohols by operation using a pseudo moving layer under a specific condition, noticing the characteristics or functionalities of rare sugar alcohols, such as allitol, tritol, sorbital, iditol, or the like. SOLUTION: In a method for chromatographically separating sugar alcohols into respective fractions, from a raw solution containing two kinds of sugar alcohols using water as the eluent, a plurality of filling columns which are filled with a calcium type cation exchange resin as an adsorbent, having a selective adsorption capability with respect to the sugar alcohols, are endlessly connected in series, to form a circulation system; and the raw solution of which the sugar alcohol concentration is 20% or higher and the eluent are supplied to the circulation system. The circulation system is divided into four zones; the respective liquid supply parts and respective fraction-withdrawing parts are successively transferred to the downstream side in the circulating direction, while holding a predetermined positional relation to form a pseudo-moving layer of the adsorbent; and the circulating solution is chromatographically separated into respective sugar alcohol fractions. COPYRIGHT: (C)2009,JPO&INPIT

80. 发明专利

JP4725811B2 Cyanato group-containing cyclic phosphazene compounds and methods of manufacturing the 有权
公开(公告)号：JP4725811B2
公开(公告)日：2011-07-13
申请号：JP2007553965
申请日：2007-01-09
申请人：株式会社伏見製薬所
发明人：卓思井上 , 祐二多田
IPC分类号： C07F9/6581 , C07F9/6593 , C08K5/5399 , C08L101/00 , C09K21/12
CPC分类号： C09K21/12 , C07F9/65815 , C07F9/65817 , C07F9/65818 , C08G79/025 , C08K5/5399 , C08L71/126 , C09K21/14

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