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61. 发明专利

JPH0369884B2 失效
公开(公告)号：JPH0369884B2
公开(公告)日：1991-11-05
申请号：JP2139782
申请日：1982-02-12
申请人： SEKISUI CHEMICAL CO LTD
发明人： KISHI TAKASHI , PPONDA SEIICHIRO , HOSOKAWA SEIYA , NAKAGAWA TAKASHI , ANDO MICHIHARU , YOSHIOKA SHOHACHI
IPC分类号： A61K9/70

62. 发明专利

JPH03146579A MEDICAL TACKY BASE 失效
公开(公告)号：JPH03146579A
公开(公告)日：1991-06-21
申请号：JP28652689
申请日：1989-11-02
申请人： SEKISUI CHEMICAL CO LTD
发明人： KISHI TAKASHI
IPC分类号： A61L15/58 , C09J133/04 , C09J133/06
摘要： PURPOSE:To obtain the inexpensive title base having tacky properties at >=a specific temperature, excellently bondable to the skin, readily releasable by local cooling, showing no irritation, consisting essentially of an acrylic ester having linear chain alkyl group containing >= specific carbons as ester residue, etc. CONSTITUTION:The objective base having tacky properties at least >=35 deg.C, for example, consisting essentially of (A) 20-80wt.% acrylic ester and/or methacrylic ester containing >=16C linear chain alkyl group as an ester residue thereof and (B) 20-80wt.% acrylic ester and/or methacrylic ester having alkyl group containing 2-8C on the average.

63. 发明专利

JPH0335284B2 失效
公开(公告)号：JPH0335284B2
公开(公告)日：1991-05-27
申请号：JP1757484
申请日：1984-02-01
申请人： SEKISUI CHEMICAL CO LTD
发明人： KISHI TAKASHI , FUKUDA MUTSUMI , ANDO MICHIHARU , MATSUMOTO KEIJIRO
IPC分类号： A61K9/70 , A61L15/44 , A61L15/58

64. 发明专利

JPH0332525B2 失效
公开(公告)号：JPH0332525B2
公开(公告)日：1991-05-13
申请号：JP6127282
申请日：1982-04-12
申请人： SEKISUI CHEMICAL CO LTD
发明人： KISHI TAKASHI , PPONDA SEIICHIRO , HOSOKAWA SEIYA , NAKAGAWA TAKASHI , ANDO MICHIHARU , YOSHIOKA SHOHACHI
IPC分类号： A61K9/70

65. 发明专利

JPH0331163B2 失效
公开(公告)号：JPH0331163B2
公开(公告)日：1991-05-02
申请号：JP7066083
申请日：1983-04-21
申请人： SEKISUI CHEMICAL CO LTD
发明人： ANDO MICHIHARU , NAKAGAWA TAKASHI , KOBAYASHI KAZUO , KISHI TAKASHI
IPC分类号： C09J7/02 , A61K9/70 , A61L15/58

66. 发明专利

JPH02193915A MEDICAL CATAPLASM 失效
公开(公告)号：JPH02193915A
公开(公告)日：1990-07-31
申请号：JP1267889
申请日：1989-01-20
申请人： SEKISUI CHEMICAL CO LTD
发明人： KISHI TAKASHI
IPC分类号： A61K9/70 , A61F13/02 , A61L15/58
摘要： PURPOSE:To obtain a medical cataplasm capable of readily adhering to a human body and free from moving and squeezing by laminating plural tacky adhesive layers on a backing support while inserting an intermediate sheet having releasing property on the both surfaces and each containing a crosslinking reaction component in one of the tacky adhesive layers and crosslinking components in the remainder. CONSTITUTION:The first tacky adhesive layer 2 (e.g. polymer consisting of 82mol octyl acrylate, 8mol butyl methacrylate and 10mol methacrylic acid and having 460000 weight average molecular weight), and the second tacky adhesive layer 4 containing an intermediate sheet 3 having release property on the both surface and crosslinking component (e.g. zinc octylate) for the first tacky agent layer are successively laminated and further protecting sheet 5 is laminated thereon. The protecting sheet 5 having release property is released from the tacky adhesive layer 4 and the intermediate sheet 3 is released while putting the tacky adhesive layer 4 thereon and turned upside down and the tacky adhesive layer 4 is bonded to the tacky adhesive layer 2 and the intermediate sheet 3 is released the exposed surface of the tacky adhesive layer 4 is pressed and applied upon an appointed part of skin. A medicine is contained in at least one layer of tacky adhesive layers 2 and 4.

67. 发明专利

JPH0278616A PLASTER 失效
公开(公告)号：JPH0278616A
公开(公告)日：1990-03-19
申请号：JP23084288
申请日：1988-09-14
申请人： SEKISUI CHEMICAL CO LTD
发明人： KISHI TAKASHI
IPC分类号： A61K9/70
摘要： PURPOSE:To obtain a plaster having improved transcutaneous absorbability by adding a drug having transcutaneous absorbability to a plaster base free from fluidity below body temperature and softening and flowing at or above the body temperature and embedding the obtained temperature-sensitive softenable plaster in a tacky adhesive layer applied to one side of a backing substrate. CONSTITUTION:The objective plaster 1 is composed of a backing substrate 2, a tacky adhesive layer 3, a protecting paper 5 and a temperature-sensitive softenable plaster 4 containing a transcutaneous absorption drug and embedded in the tacky adhesive layer. The plaster base constituting the temperature- sensitive softenable plaster 4 has a softening point lower than the human body temperature and is e.g., a composition composed mainly of rosin ester resin, polyterpene resin, beeswax or polyethylene glycol. The above plaster is storable without causing the bleed-out, dissipation, lowering of the activity and degradation of the drug component. It has improved drug availability, is stably storable over a long period, can contain increased amount of the drug per one sheet of the plaster and is producible at a low cost.

68. 发明专利

JPS63309572A MEDICAL SELF-ADHESIVE COMPOSITION AND ITS PRODUCTION 失效
公开(公告)号：JPS63309572A
公开(公告)日：1988-12-16
申请号：JP14548187
申请日：1987-06-10
申请人： SEKISUI CHEMICAL CO LTD
发明人： KISHI TAKASHI
IPC分类号： A61K9/70 , A61L15/16 , A61L24/00 , C08L5/00 , C09J105/00 , C09J133/04
摘要： PURPOSE:To obtain the title composition which does not dissolve rapidly even in the presence of water and can adhere for a long time, by adding an aqueous solution of a specified water-soluble polymer to a solution of a polymaltotriose and an alcoholic softener. CONSTITUTION:An aqueous emulsion or suspension of a water-insoluble polymer (B) comprising an alkyl (meth)acrylate polymer or/and its copolymer is added to a homogeneous solution containing a polymer (A) comprising maltotriose and an alcoholic softener and dispersed in it to form an emulsion or a suspension. Examples of said alcoholic softener which can be desirably used include glycerol, diglycerol, triglycerol, polyglycerol (tetramer or higher polymer) and sorbitol. According to this process, a suitable amount of said softener is added to said polymer (A) having tackiness, adhesiveness, hydrophilicity and water solubility, so that flexibility is imparted to it and its hydrophilicity is enhanced and its adhesiveness to a wet surface is improved.

69. 发明专利

JPS63280014A PLASTER COMPOSITION FOR BAD BREATH PREVENTION 失效
公开(公告)号：JPS63280014A
公开(公告)日：1988-11-17
申请号：JP11558587
申请日：1987-05-12
申请人： SEKISUI CHEMICAL CO LTD
发明人： KISHI TAKASHI , IWAKAWA MASAHARU
IPC分类号： A61K8/00 , A61K8/73 , A61Q11/00 , A61Q15/00
摘要： PURPOSE:To obtain the title composition that can suppress bad breath for many hours by using cyclodextrin or its derivative and a shape-retaining base which is soluble in water, flexible, when it absorbs water, and tacky to oral mucosa. CONSTITUTION:The subject composition contains (A) a shape-retaining base which is soluble in water, flexible, at least when it absorbs water, and sticky to oral mucous membranes, usually a 85/15-15/85 weight ratio mixture of a high polymeric compound which is soluble in water and physiologically inert such as a carboxyvinyl polymer, polyacrylic acid and a softening agent which is compatible with the high polymeric compound, physiologically inert and retains moisture or water such as glycerol or polyethylene glycol and (B) at least one from alpha-, beta- and gamma-cyclodextrins and their derivatives such as a cyclodextrin bearing maltose as a side chain. The amount of component B is over 3wt.%, usually 5-50wt.% based on the composition.

70. 发明专利

JPS63280010A PLASTER FOR PREVENTING ARMPIT ODOR 失效
公开(公告)号：JPS63280010A
公开(公告)日：1988-11-17
申请号：JP11558187
申请日：1987-05-12
申请人： SEKISUI CHEMICAL CO LTD
发明人： KISHI TAKASHI
IPC分类号： A61K8/00 , A61K8/73 , A61K8/87 , A61Q15/00
摘要： PURPOSE:To obtain the titled plaster easily applicable to human body and effective in continuously preventing armpit odor, by applying a tacky adhesive layer containing cyclodextrins to at least one surface of a substrate consisting of a specific nonwoven cloth composed mainly of polyurethane fiber. CONSTITUTION:The objective plaster for preventing armpit odor is composed of a substrate having a tacky adhesive layer on at least one surface of the substrate, wherein said substrate is composed of a nonwoven cloth having an elongation of >=100%, preferably >=150% and composed mainly of polyurethane fiber and said tacky adhesive layer contains >=3wt.%, preferably >=5wt.% of cyclodextrin and/or its derivative. Armpit odor can be eliminated continuously over a long period by applying the plaster to the armpit of human body. The plaster is resistant to peeling off and is applicable without causing disagreeable feeling or paint to the skin nor causing stuffing of the skin because the substrate is stretchable according to the stretching of the skin and has moisture permeability. Furthermore, the plaster can be easily applied to and peeled off from the skin as necessary.

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