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41. 发明专利

JPH0318452B2 失效
公开(公告)号：JPH0318452B2
公开(公告)日：1991-03-12
申请号：JP3823585
申请日：1985-02-27
申请人： YOKOGAWA ELECTRIC CORP
发明人： HIRATA TAKAAKI , MATSURA HIROYUKI , SUGYAMA SUNAO , IWAOKA HIDETO
IPC分类号： A61B10/00 , A61B5/055 , G01R33/48 , G01R33/50 , G06F3/00 , G06F3/01

42. 发明专利

JPH01502723A 失效
公开(公告)号：JPH01502723A
公开(公告)日：1989-09-21
申请号：JP50257288
申请日：1988-03-15
IPC分类号： A61B5/055 , G01R33/48 , G01R33/50 , G01R33/561

43. 发明专利

JPS62189055A METHOD FOR GENERATING NMR IMAGE 失效
公开(公告)号：JPS62189055A
公开(公告)日：1987-08-18
申请号：JP30897786
申请日：1986-12-26
申请人： GEN ELECTRIC
发明人： JIEEMUZU RATSUSERU MAKUFUAARU , GARII HARORUDO GUROOBAA
IPC分类号： A61B10/00 , A61B5/055 , G01R33/48 , G01R33/50 , G01R33/56

44. 发明专利

JPS61148357A NMR IMAGING APPARATUS 失效
公开(公告)号：JPS61148357A
公开(公告)日：1986-07-07
申请号：JP27040584
申请日：1984-12-21
申请人： HITACHI LTD
发明人： TSUDA MUNETAKA , HIGUCHI KAZUTOSHI
IPC分类号： A61B10/00 , A61B5/055 , G01R33/48 , G01R33/50 , G01R33/54
摘要： PURPOSE:To relieve a person to be inspected of a pain with the reduced inspection time of a sample, by applying a series of continuous high frequency magnetic field pulses containing a gradient magnetic field sequentially to the sample to take a plurality of NMR images simultaneously. CONSTITUTION:A system control section 11 is connected to a frequency synthesizer 9 to allow the application of a frequency control signal thereto for the generation of pulse trains as illustrated. Then, a pi pulse is applied with the resonance frequency of 6.375MHz corresponding to the first slicing position. A pi pulse is applied with the resonance frequency of 6.3763MHz corresponding to the second slicing position. Likewise, a pi pulse is applied with the resonance frequency of 6.3776MHz corresponding to the third slicing position and a pipulse done with the resonance frequency of 6.3789MHz corresponding to the fourth slicing position. In this manner, high frequency magnetic field pulses are applied sequentially to take a plurality of NMR images simultaneously thereby relieving a person to be inspected of a pain with a reduced inspection time of the sample.

45. 发明专利

JPS61122851A Method and apparatus for performing non-invasion test of breast 失效
标题翻译：用于进行乳腺非侵入性测试的方法和装置
公开(公告)号：JPS61122851A
公开(公告)日：1986-06-10
申请号：JP21360685
申请日：1985-09-26
申请人： Southwest Res Inst
发明人： UIRIAMU ERU ROORUUITSUTSU
IPC分类号： A61B10/00 , A61B5/055 , A61B8/08 , G01R33/34 , G01R33/38 , G01R33/48 , G01R33/50
CPC分类号： G01R33/34053 , A61B8/0825 , A61B8/406 , G01R33/383 , G01R33/50
摘要： A method and apparatus for testing for cancer cells in the human breast is set forth. In the preferred and illustrated embodiment, a pendulant breast exposed to a magnetic field is tested by nuclear magnetic resonant (NMR). The magnetic field is varied to provide the requisite field intensity in selected segmented sections of the pendulant breast within the field. The field intensity is varied to thereby observe all of the breast extending toward the thorax cavity, obtaining test data from section after section aggregating test data from the entire breast within the pole pieces of the magnet and sufficiently therebeyond to obtain full interrogation. The NMR response focuses on hydrogen nuclei in the water in the breast region, determines the voltage proportional to the density of hydrogen nuclei and the binding of the water described by the relaxation times T1 and T2 for each binding level for water. The data so obtained in sequence is examined. Difference values from sequentially obtained signals are evaluated, yielding a plot of different signals as a function of breast length, thereby yielding abnormalities. Such abnormalities are shown in the difference signal from NMR interrogation as a result the concentration and relaxation time (T1 and T2

46. 发明专利

JPS60230043A MEASURING METHOD OF LONGITUDINAL RELAXATION TIME 失效
公开(公告)号：JPS60230043A
公开(公告)日：1985-11-15
申请号：JP8660884
申请日：1984-04-27
申请人： ASAHI CHEMICAL IND , ASAHI MEDICAL CO
发明人： YAMAZAKI TATSUO , HATASE AKIRA
IPC分类号： A61B10/00 , A61B5/055 , G01R33/48 , G01R33/50
摘要： PURPOSE:To improve measurement precision by using >=3 IR and/or SR pulses which differ in wait time as high-frequency pulses and measuring a longitudinal relaxation time from a nuclear magnetic resonance signal (NMR signal). CONSTITUTION:High-frequency pulses irradiate a body 13 to be measured from an RF coil 16 use >=3 IR and/or SR pulses which have different wait times tau and a space distribution is calculated from plural obtained NMR signals at intervals of the wait time tau. Then plural NMR signals at a corresponding point in the space distribution are used to calculate longitudinal relaxation time T1 at the point by a repetitive time correction nonlinear type minimum square-law approximating method, thereby obtaining longitudinal relaxation time distribution information. Thus, the longitudinal relaxation time is calculated in a relatively short measurement time with high precision.

47. 发明专利

JPS60149953A NMR IMAGING APPARATUS 失效
公开(公告)号：JPS60149953A
公开(公告)日：1985-08-07
申请号：JP481684
申请日：1984-01-17
申请人： HITACHI LTD
发明人： MATSUI SHIGERU , YAMAMOTO ETSUJI , SHIONO HIDEKI , KOUNO HIDEKI
IPC分类号： A61B10/00 , A61B5/055 , G01N24/08 , G01R33/50
摘要： PURPOSE:To make it possible to perform the measurement and imaging of a transverse relaxation time (T2) value in a good SN ratio, by using a steady state free precession (SSFP) method. CONSTITUTION:A high frequency pulse with intensity H1 and a width tau is continuously applied to a spin system at time intervals T sufficiently shorter than T1 but about 1/4 times of T2. In this case, for example, in order to selectively obtain only the signal in a plane of Z=Z0, a vibration magnetic field gradient G is applied in a Z-direction as shown by the drawing (d) and, in order to further obtain the projected image of the intra-plane signal selected as shown by the drawing (c) toward various directions in an XY-plane, a rotary magnetic field gradient GXY is applied in the XY-plane. At this time, a signals appearing steadily directly after and before the high frequency pulse are independently added at a high speed and data processing such as Fourier conversion or reverse projection is performed. If the ratio of two obtained images is taken, because T is known, the image of a T2-value can be obtained by using formula (wherein S+ and S- are signals similar directly after and before the high frequency pulse).

48. 发明专利

JPS59231438A INSPECTION METHOD AND APPARATUS BY NUCLEAR MAGNETIC RESONANCE 失效
公开(公告)号：JPS59231438A
公开(公告)日：1984-12-26
申请号：JP10578483
申请日：1983-06-15
申请人： YOKOGAWA HOKUSHIN ELECTRIC
发明人： IWAOKA HIDETO , SUGIYAMA SUNAO , MATSUURA HIROYUKI
IPC分类号： A61B10/00 , A61B5/055 , G01R33/48 , G01R33/50 , G01R33/561 , G01N24/08
摘要： PURPOSE:To calculate transition times T1 and T2 simply with the magnetization M forcibly turned in the Z' direction by determining at least one 2-D and/or 3-D image of a spin-lattice transition time T1, a spin-spin transition time T2 and a nuclear density from intensity values of a plurality of nuclear magnetic resonance signals through an inter-image computation. CONSTITUTION:A control circuit 2 of a static magnetic field coil 1 contains, for example, a DC stabilization power source. A grade magnetic field coil 3 contains a Z grade magnetic field coil 31, (y) grade magnetic field coils 32 and 33 and an (x) grade magnetic field coil which is the same in the shape as (y) grade magnetic field coils 32 and 33 not illustrated and set turned by 90 deg.. This grade magnetic field coil generates a magnetic field having straight grade respectively in the (x), (y) and (z) axis directions by a magnetism in the same direction as an even static magnetic field H0. Numeral 60 indicates the controller of a control circuit 4. An excitation coil 5 gives a body to be inspected an RF pulse of a fine frequency spectrum (f) as an electromagnetic wave. A detection coil 7 for detecting an NMR resonance signal in the body being detected is the same as the excitation coil and is set turned by 90 deg. with respect to the excitation coil 5. Thus, when energization is forcibly returned to the normal using a pulse series after applied, the transition times T1 and T2 and the proton density M can be determined simply by a computation observing the current intensity of the NMR signal.

49. 发明专利

JPS59214745A High-speed nuclear magnetic resonance image forming system 失效
标题翻译：高速核磁共振成像系统
公开(公告)号：JPS59214745A
公开(公告)日：1984-12-04
申请号：JP2945184
申请日：1984-02-17
申请人： Makofusukii Arubaato
发明人： ARUBAATO MAKOFUSUKII
IPC分类号： A61B10/00 , A61B5/04 , A61B5/055 , G01R33/48 , G01R33/50 , G01R33/54 , G01R33/561 , G01N24/08
CPC分类号： G01R33/561 , G01R33/50 , G01R33/54
摘要： A cross-sectional relaxation time sensitive image of the NMR activity in the body is formed by taking a sequence of projections, each having a different transverse gradient structure. The sequence of projection signals are processed so as to represent an acquisition at a specific desired time.

50. 发明专利

JP2019529871A 周辺分布を使用した多次元分光NMRおよびMRI 审中-公开
公开(公告)号：JP2019529871A
公开(公告)日：2019-10-17
申请号：JP2019506625
申请日：2017-08-11
申请人：ザユナイテッドステイツオブアメリカ, アズリプレゼンテッドバイザセクレタリー, デパートメントオブヘルスアンドヒューマンサービシーズ
发明人：バッサー, ピータージェイ. , ベンジャミニ, ダンエイチ.
IPC分类号： A61B5/055 , G01N24/00 , G01N24/12 , G01R33/561 , G01R33/50 , G01N24/08
摘要：試料に関連付けられた多次元スペクトルが、より低次元のスペクトルを制約として使用して再構成される。例えば、拡散率およびスピン格子緩和時間に関連付けられた2次元スペクトルが、それぞれ、拡散率およびスピン格子緩和時間に関連付けられた1次元スペクトルを制約として使用して得られる。完全な2次元スペクトルに関するデータは、取得されず、著しく低減されたデータ取得時間につながる。一実施形態において、磁気共鳴(MR)システムは、MRデータ取得システムと、MRデータ取得システムに結合されているMRデータプロセッサとを備え、MRデータプロセッサは、第1および第2の周辺分布を制約として使用して試料に関連付けられた2次元MRスペクトルを再構成するように動作可能である。

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