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31. 发明专利

JPH0731311A NOVEL PLANT OF PERILLA, LAVANDULA AND PRODUCTION THEREOF AND REPRODUCTION METHOD 失效
公开(公告)号：JPH0731311A
公开(公告)日：1995-02-03
申请号：JP17825593
申请日：1993-07-19
申请人： POLA CHEM IND INC
发明人： SUGA CHIHOKO , SOEYA AKIJI , SATO NORIO , OKA NORIAKI , FUKUSHIMA MAKOTO , KIMURA TOMOSHI
IPC分类号： A01H5/00
摘要： PURPOSE:To obtain a plant of lavender which has a highly effective property in releasing a lot of immunoglobulins (mainly secretory immunoglobulin A) into the saliva when an odor of the flower is smelt. CONSTITUTION:Plants are obtained by first castrating unblown flowers of a lavender (Lavandula angstifolia) and applying pollens of a spike lavender (Lavandula latifolia) to the pistils of the lavender, germinating seeds derived from the above, and bringing the germinated seedlings up. Among these plants an individual plant which promotes immunoglobulin content in the saliva of those who smell the odor of the flower of the plant, is selected and the individual plant is asexually reproduced by following a conventional method.

32. 发明专利

JPH0720115A METHOD FOR MEASURING TASTE OF FRAGRANCE 失效
公开(公告)号：JPH0720115A
公开(公告)日：1995-01-24
申请号：JP18672593
申请日：1993-06-30
申请人： POLA CHEM IND INC
发明人： SUGA CHIHOKO , OKA NORIAKI , FUKUSHIMA MAKOTO , KIMURA TOMOSHI
IPC分类号： A61B10/00 , G01N33/00 , G01N33/50 , G01N33/53
摘要： PURPOSE:To measure the taste of fragrance objectively and quantitatively by measuring the concentration of immunoglobulin in a saliva sampled from a person who smelt a sample. CONSTITUTION:Saliva is sampled from a person before and after smelling a sample and immunoglobulin, especially secretory immunoglobulin A, is determined. If the concentration in the saliva is increased after smelling the sample, a decision is made that the taste of fragrance is high and the degree of taste is determined depending on the increase of concentration. This method is preferably employed in the measurement by a plurality of measuring persons because positive results can be obtained with high reproducibility. The immunoglobulin can be determined by an antibody method using an antibody for the immunoglobulin. The quantity of antigen is measured based on the quantity of antigen coupled with the immunoglobulin by direct method, sandwich method, etc. The sandwich method is preferably employed because it can be operated easily.

33. 发明专利

JPS6438013A PROMOTER FOR HAIR RESTORATION AND HAIR GROWTH 失效
公开(公告)号：JPS6438013A
公开(公告)日：1989-02-08
申请号：JP19207687
申请日：1987-07-31
申请人： POLA CHEM IND INC
发明人： INAOKA YASUNORI , FUKUSHIMA MAKOTO , KURODA HIDEO
IPC分类号： A61K8/00 , A61K8/97 , A61Q5/00 , A61Q7/00
摘要： PURPOSE:To obtain a cosmetic for hair restoration and hair growth continuously usable without strong irritation, having excellent effects, containing an active ingredient extracted from a crude drug of Ligustrum lucidum Ait., Angelica dahurica Benth, et Hook, or Curcuma zedoaria Rosc. with a water-insoluble organic solvent or a hydrous solvent thereof. CONSTITUTION:100g crude drug of Ligustrum lucidum Ait., Angelica dahurica Benth. et Hook. or Curcuma zedoaria Rosc. is extracted with 1l organic solvent such as primary alcohol (e.g. methanol or butanol), acetone, THF or dioxane alone or hydrous organic solvent containing >=50wt.% the organic solvent for 2hr each time 3 times, the extracted essence is put together, filtered by suction and concentrated under reduced pressure to give viscous essence of crude drug. 0.5-5.0wt.% of the essence as an active ingredient is directly added to a base or dissolved or dispersed in a proper solvent and diluted and added as the active ingredient to the base to give a promoter for hair restoration and growth.

34. 发明专利

JPS63198613A TRICHOGENOUS HAIR-GROWING AGENT 失效
公开(公告)号：JPS63198613A
公开(公告)日：1988-08-17
申请号：JP3125187
申请日：1987-02-13
申请人： POLA CHEM IND INC
发明人： INAOKA YASUNORI , FUKUSHIMA MAKOTO , KURODA HIDEO
IPC分类号： A61K8/00 , A61K8/97 , A61Q5/00 , A61Q7/00
摘要： PURPOSE:To produce a safe trichogenous hair-growing agent free from skin stimulation, by using an active component produced by extracting a herb drug KANTSUI (dried root of Euphorbia kantsui) or TAKUSHITSU( Euphorbia helioscopia L.) with a water-soluble organic solvent or its mixture with water. CONSTITUTION:The objective trichogenous hair-growing agent contains 0.5-5.0wt.% extract of crude drug KANTSUI or TAKUSHITSU. The above crude drug extract is a viscous substance produced by extracting KANTSUI or TAKUSHITSU with an organic solvent such as methanol, ethanol, acetone, THF, dioxane, etc., or its mixture with water 3 times for 2hr each under warming. The crude drug extract is optionally dissolved, dispersed or diluted with a proper solvent and is compounded to a base to produce a trichogenous hair- growing agent. The trichogenous hair-growing agent is safe to the skin and can be continuously applied without causing dermatitis, etc.

35. 发明专利

JPS63198612A TRICHOGENOUS HAIR-GROWING AGENT 失效
公开(公告)号：JPS63198612A
公开(公告)日：1988-08-17
申请号：JP3125087
申请日：1987-02-13
申请人： POLA CHEM IND INC
发明人： INAOKA YASUNORI , FUKUSHIMA MAKOTO , KURODA HIDEO
IPC分类号： A61K8/00 , A61K8/97 , A61Q5/00 , A61Q7/00
摘要： PURPOSE:To produce a safe trichogenous hair-growing agent free from skin stimulation, by using an active component produced by extracting a herb drug ZOKUZUISHI (dried seed of Euphorbia lathyris) or DAIGEKI (dried root of Knoxia corymbosa) with a water-soluble organic solvent or its mixture with water. CONSTITUTION:A herb drug ZOKUZUISHI or DAIGEKI is extracted with an organic solvent such as methanol, ethanol, acetone, THF, dioxane, etc., or its mixture with water 3 times for 2hr each under warming. The obtained viscous extract of the herb drug is used as an active component of the objective trichogenous hair-growing agent. The crude drug extract is optionally dissolved, dispersed or diluted with a proper solvent and is compounded to a base to produce a trichogenous hair-growing agent. The amount of the extract in the agent is 0.5-5.0wt.%. The trichogenous hair-growing agent is safe to the skin and can be continuously applied without causing dermatitis, etc.

36. 发明专利

JPS6377808A COSMETIC 失效
公开(公告)号：JPS6377808A
公开(公告)日：1988-04-08
申请号：JP22117986
申请日：1986-09-19
申请人： POLA CHEM IND INC
发明人： MAEDA TETSUO , KURIHARA TOSHIO , SUZUKI MASAMI , FUKUSHIMA MAKOTO
IPC分类号： A61K36/18 , A61K8/00 , A61K8/34 , A61K8/92 , A61K8/96 , A61K8/97 , A61P17/00 , A61Q5/00 , A61Q7/00 , A61Q19/00
摘要： PURPOSE:To obtain a cosmetic having improved suppressing effects on sebum secretion, remedying effects on pimple, etc., by blending a cosmetic with an extract prepared from Alisma plantagoaquatica L. CONSTITUTION:A cosmetic which contains preferably 0.1-5wt% based on total amount of cosmetic of an extract from Alisma plantagoaquatica L., preferably an extract with an alcohol or with a hydrous alcohol as an active ingredient, shows excellent effects on improvement in pimple, preventing effects on skin greasiness, oily gloss, etc., can prevent makeup collapse caused by excess secretion of sebum and is especially useful for pimple and acne. These effects are considered to be obtained by mechanism wherein the active ingredient acts on skin, suppresses excess secretion of sebum and maintains the amount of sebum on the skin at a proper level. The amount of fats and oils which are contained in the cosmetic and likely cause greasiness is preferably

37. 发明专利

JPS61271210A COSMETIC 失效
公开(公告)号：JPS61271210A
公开(公告)日：1986-12-01
申请号：JP11445585
申请日：1985-05-28
申请人： POLA CHEM IND INC
发明人： FUKUSHIMA MAKOTO , MATSUDA KAZUO , HOSHIZAKI SADAO
IPC分类号： A61K8/00 , A61K8/96 , A61K8/97 , A61K36/25 , A61K36/53 , A61P43/00 , A61Q5/00 , A61Q7/00 , A61Q19/02
摘要： PURPOSE:A cosmetic, containing an extract component prepared by extracting the root of Salvia miltiorrhiza Bunge, etc. as an active constituent, having improved skin beautifying effect and beautifying and whitening effect and humectant effect and capable of producing effect, e.g. tension, gloss, smoothness, etc. of the skin by using in cream, toilet water, etc. CONSTITUTION:A cosmetic containing an extract component prepared by extracting the dried root of Salvia miltorrhiza Bunge or Salvia przewalskii Maxim. var. mandarinorum Stib. as an active constituent. The Salvia miltiorrhiza Bunge or Salvia przewalskii Maxim. var. mandarinorum Stib. is a perennial plant belonging to the genus Labiatae. The extract thereof is obtained by cutting the dried root of the Salvia miltiorrhiza Bunge or Salvia przewalskii Maxim. var. mandarinorum Stib. to fragements having

38. 发明专利

JPS59116211A Hair tonic and hair growing agent 失效
标题翻译：头发和头发生长剂
公开(公告)号：JPS59116211A
公开(公告)日：1984-07-05
申请号：JP23305082
申请日：1982-12-23
申请人： Pola Chem Ind Inc
发明人： FUKUSHIMA MAKOTO , HORIKAWA TOSHIO
IPC分类号： A61K8/00 , A61K8/97 , A61Q5/00 , A61Q7/00
CPC分类号： A61K8/97 , A61Q7/00
摘要： PURPOSE:To provide the titled agent free from skin stimulation, and containing an extract prepared by extracting MANKEISHI (fruit of Vitex rotundifolia) or SHIN-I (bud of Magnolia fargesii) with a water-soluble organic solvent or a mixture of said solvent and water. CONSTITUTION:The objective hair growing and hair tonic agent contains 0.1- 5.0wt% of the extract of MANKEISHI or SHIN-I. The extract can be prepared by immersing the MANKEISHI or SHIN-I in an organic solvent such as primary alcohol, acetone, THF, dioxane or a hydrated organic solvent containing >=50wt% of the above organic solvent three times for 2hr each under heating, filtering the solution with suction, and concentrating to dryness in vacuum. The obtained viscous product, if necessary, is dissolved in, dispersed in or diluted with a solvent, etc., and compounded in a base to obtain the objective hair tonic and hair growing agent.
摘要翻译：目的：提供无皮肤刺激的标签试剂，并含有通过水溶性有机溶剂或所述溶剂和所述溶剂的混合物提取MANKEISHI（Vitex rotundifolia的水果）或SHIN-I（Magnolia fargesii的芽）制备的提取物水。构成：客观的头发生长和滋润剂含有人造石或SHIN-I提取物的0.1- 5.0重量％。提取物可以通过将MANKEISHI或SHIN-I在有机溶剂如伯醇，丙酮，THF，二恶烷或含有≥50wt％上述有机溶剂的水合有机溶剂中浸渍3次，每次加热2小时来制备，抽吸过滤溶液，真空浓缩干燥。如果需要，将得到的粘稠产物溶解于其中，分散于溶剂等中或稀释后，在碱中混合，得到客观的毛发滋养剂。

39. 发明专利

JP2003238431A STRESS MICROCIRCULATION DISORDER-IMPROVING AGENT AND COMPOSITION FOR ORAL ADMINISTRATION TO MAKE SKIN BEAUTIFUL 审中-公开
公开(公告)号：JP2003238431A
公开(公告)日：2003-08-27
申请号：JP2002035491
申请日：2002-02-13
申请人： ISHIDA KINJI , KAIKEN KK , POLA CHEM IND INC
发明人： TSUJI KUNIO , ISHIDA KINJI , SHIBATA TOSHIO , MATSUMOTO KATSUO , FUKUSHIMA MAKOTO
IPC分类号： A23L1/30 , A61K36/18 , A61P9/08 , A61P17/00 , A61P37/08 , A61K35/78
摘要： PROBLEM TO BE SOLVED: To provide an improving means for skin roughness caused by microcirculation disorder by a stress-overcoming means through a total body system. SOLUTION: A stress microcirculation disorder-improving agent consisting of the plant body and/or extract of tea of Theaceae is processed to an oral administration composition such as a medicine or food together with optional components for making a preparation. The preferable form of the stress microcirculation disorder-improving agent is provided by reducing a water content to 6-8% by irradiating for heating the leaf part of the tea at approximately 50°C and also inactivating enzymes, and then crushing for processing to ≤1 micron fine powder. The preferable form of the oral administration composition is the form of processing it to tablets and applying an enteric coating on them. COPYRIGHT: (C)2003,JPO

40. 发明专利

JP2003230363A ROYAL JELLY PREPARATION 审中-公开
公开(公告)号：JP2003230363A
公开(公告)日：2003-08-19
申请号：JP2002030197
申请日：2002-02-07
申请人： POLA CHEM IND INC
发明人： KAMAKURA MASAKI , FUKUSHIMA MAKOTO
IPC分类号： A23L21/20 , A61K9/48 , A61K35/64 , A61K35/644 , A61K47/12 , A61K47/14 , A61K47/38 , A61K47/42 , A61K47/44 , A61P3/02 , A23L1/076
摘要： PROBLEM TO BE SOLVED: To provide a royal jelly preparation stably sustaining an active ingredient. SOLUTION: This royal jelly-containing preparation for oral administration contains as the ingredient (1) a capsule coated with an enteric coating composition and (2) a royal jelly-containing composition. The royal jelly-containing composition is filled and sealed in the coated capsule to be administered by oral administration. It is preferable that the enteric coating composition contains a plasticizer and the royal jelly-containing composition contains e.g. citric acid, malic acid, succinic acid, edetic acid. COPYRIGHT: (C)2003,JPO

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