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1. 发明专利

JP2002335883A METHOD FOR PRODUCING RAW ROYAL JELLY 失效
公开(公告)号：JP2002335883A
公开(公告)日：2002-11-26
申请号：JP2001146108
申请日：2001-05-16
申请人： POLA CHEM IND INC
发明人： KAMAKURA MASAKI , MIYAZAKI HIROTAKA , FUKUSHIMA MAKOTO , ODA TADANOBU
IPC分类号： A23L21/20 , A23L1/076
摘要： PROBLEM TO BE SOLVED: To provide a method for producing a raw royal jelly while keeping the active ingredients. SOLUTION: The method for producing a fresh raw royal jelly while keeping the protein of 57 kD which is an active ingredient of the jelly is provided. The method comprises collection of royal jelly in spring or autumn, a preservation treatment within 48 hr after collection and a quick cooling for preservation. The preservation treatment is composed of a filtering step, a homogenizing step, a dividing step, a quick cooling step at

2. 发明专利

JP2001213795A MEDICINE FOR RELIEVING STRESS AND DERMATOLOGIC MEDICINE CONTAINING THE SAME 失效
公开(公告)号：JP2001213795A
公开(公告)日：2001-08-07
申请号：JP2000025795
申请日：2000-02-03
申请人： POLA CHEM IND INC , ISHIDA KINJI , TSUJI KUNIO
发明人： ISHIDA KINJI , TSUJI KUNIO , MATSUMOTO KATSUO , NISHIMORI YASUTOMO , KAWAI MITSUO , MITANI MAKOTO , FUKUSHIMA MAKOTO
IPC分类号： A61K8/96 , A61K8/97 , A61K36/18 , A61P17/00 , A61K35/78 , A61K7/00
摘要： PROBLEM TO BE SOLVED: To provide a means for preventing the adverse effects of loaded stress on a living body. SOLUTION: The medicine for relieving stress that consists of plant essence of (Japanese) honeysuckle family and is allowed to be contained in the composition of cosmetics, dermatologic medicines, oral drugs to obtain prophylactic and/or therapeutic compositions to eliminate the adverse effects of stress on a living body.

3. 发明专利

JP2000290129A PURIFICATION OF PHYSIOLOGICALLY ACTIVE SUBSTANCE INCLUDED IN SOYBEAN 失效
公开(公告)号：JP2000290129A
公开(公告)日：2000-10-17
申请号：JP9442999
申请日：1999-04-01
申请人： POLA CHEM IND INC , CHANSON KESHOHIN KK
发明人： TANAKA MASATO , TSUNEKI AKIRA , FUKUSHIMA MAKOTO , MITANI MAKOTO
IPC分类号： A23G3/34 , A23G3/00 , A23L1/30 , A61K8/00 , A61K8/49 , A61K8/96 , A61K8/97 , A61K31/00 , A61K36/48 , A61P1/00 , A61P1/10 , A61P7/00 , A61P7/10 , A61Q19/10 , A61K7/00 , A61K7/50 , A61K35/78
摘要： PROBLEM TO BE SOLVED: To obtain a physiologically active substance included in soybean in high yield by solvent/solvent extracting the nonvolatile constituent with water and an organic solvent immiscible with water in arbitrary ratio after extracting soybean or its finished articles with a polar solvent. SOLUTION: The physiologically active substance (e.g.; soybean isoflavone and its glucoside or the like) is obtained by extracting soybean and/or its finished articles [e.g.; soybean itself, julienne of dried soybean and its embryo bud, residue of oil and fat squeeze or solvent extract residue (oil cake of soybean) or husk, embryo bud or the like], using 1-10 times of a polar solvent (e.g.; alcohols or the like), leaving alone a few days at room temperature, or a few hours at the temperature close to boiling point of the solvent, under agitation if necessary, after immersing and extracting the nonvolatile ingredient of the above described extract is solvent/solvent extracted with water and the organic solvent (e.g.; normal butanol or the like) immiscible with water in arbitrary ratio, removing organic solvent by vacuum concentration or the like from the obtained organic solvent layer.

4. 发明专利

JP2000103718A COMPOSITION FOR IMPROVING ACTIVITY OF LIVING BODY 失效
公开(公告)号：JP2000103718A
公开(公告)日：2000-04-11
申请号：JP29001998
申请日：1998-09-28
申请人： POLA CHEM IND INC
发明人： KOSUGE TAKUO , FUKUSHIMA MAKOTO , MITANI MAKOTO , MATSUMOTO KATSUO , NISHIMORI YASUTOMO , KAWAI MITSUO
IPC分类号： A23L1/30 , A61K8/00 , A61K8/23 , A61K8/25 , A61K8/96 , A61K8/97 , A61K8/98 , A61K31/00 , A61K36/00 , A61P1/00 , A61P3/00 , A61P7/00 , A61P7/10 , A61P17/00 , A61P43/00 , A61Q19/00 , A61K7/00 , A61K7/48 , A61K35/78
摘要： PROBLEM TO BE SOLVED: To obtain a composition not only improving activity of living body such as skin care action and improving action on dermatosis such as atopic dermatitis, eczema, dermatomycosis, pigmentation, psoriasis vulgaris, senile xeroderma, senile keratoma, burn, hair growth promoting action, sweating promoting action, digestive fluid secretion promoting action, diuretic action, constipation promoting action, or the like, but also further bettering activity mainly of a supply system of a substance group related to the development of function of human body. SOLUTION: This composition for improving activity of living body, such as a health food, a medicine, a cosmetic contains one or more kinds selected from essences of crude medicines and their active ingredients having promoting actions on metabolism related to body fluid such as digestive fluid, saliva, urine, and one or more selected from essences of crude medicines having hematic action and blood activating action.

5. 发明专利

JPH11228434A ENERGY UTILIZATION PROMOTER 失效
公开(公告)号：JPH11228434A
公开(公告)日：1999-08-24
申请号：JP4285698
申请日：1998-02-09
申请人： POLA CHEM IND INC
发明人： FUKUSHIMA MAKOTO , YAMAMOTO MAKOTO , FUKUDA TOSHIYUKI , ABE SHINOBU
IPC分类号： A23L1/30 , A61K36/18 , A61K36/23 , A61K36/73 , A61K36/75 , A61P3/00 , A61P43/00 , A61K35/78
摘要： PROBLEM TO BE SOLVED: To provide a means for raising the avaliability of glycogen and fat or the like accumulate but not utilized in vivo to remedy various symptoms caused by such supply energy shortage. SOLUTION: This means comprises incorporating a composition such as food with at least one kind of the subject energy utilization promoter selected from the respective essences of lonicerae flos, Crataegus cuneata, Glycyrrhiza glabra, cassia seed, Citrus aurantium, Mentha herb, cassia, Glehnia littoralis, Sesamum indicum, adenophorae radix, Platycodon grandiflorum, Zizyphus vulgaris, eriobotryae folium, Cornus officinalis, Indian saffron, Cucumis sativus, Plantago seed, raw persimmon, Ganoderma lucidum, Curculiginis rhizoma and, etc.

6. 发明专利

JPH10114652A IMPROVER FOR AQUEOUS BODY FLUID AND COMPOSITION FOR ORAL ADMINISTRATION COMPRISING THE SAME 失效
公开(公告)号：JPH10114652A
公开(公告)日：1998-05-06
申请号：JP27272596
申请日：1996-10-15
申请人： DOCTORS COSMETICS KK , POLA CHEM IND INC
发明人： KOSUGE MASANORI , KOSUGE TAKUO , FUKUSHIMA MAKOTO , INAOKA YASUNORI , OKUDA TAKEHIRO
IPC分类号： A23L1/30 , A61K8/00 , A61K8/30 , A61K8/36 , A61K8/365 , A61K31/20 , A61P1/00 , A61P1/10 , A61P3/00 , A61P7/10 , A61P17/00 , A61P29/00 , A61P43/00 , A61Q5/00 , A61Q19/00 , A61K7/00 , A61K7/06 , A61K7/48
摘要： PROBLEM TO BE SOLVED: To prepare an improver for aqueous body fluids (water), capable of improving actions of the aqueous body fluids and a composition for oral administration such as a food or a medicine comprising the humor improving agent. SOLUTION: This improver for aqueous body fluids (water) comprises a hydroxy-fatty acid and/or its physiologically permissible salt (10-hydroxydecenoic acid, ipurolic acid, hydroxystearic acid, 9,10-dihydroxystearic acid, etc.). The improver for the aqueous body fluids is compounded to afford a composition for oral administration such as a food or a medicine.

7. 发明专利

JPH09188629A MEDICINE FOR INHIBITING ANTIBODY-PRODUCING CELL AND COMPOSITION CONTAINING THE SAME 失效
公开(公告)号：JPH09188629A
公开(公告)日：1997-07-22
申请号：JP1719096
申请日：1996-01-06
申请人： POLA CHEM IND INC
发明人： NISHIMURA KEIICHI , FUKUSHIMA MAKOTO , YAMAMOTO MAKOTO , FUKUDA TOSHIYUKI , ABE SHINOBU
IPC分类号： A23G3/34 , A23G3/00 , A23L1/30 , A61K38/00 , A61P17/00
摘要： PROBLEM TO BE SOLVED: To obtain the subject highly safe medicine capable of inhibiting the antibody-producing cells of a spleen, etc., and useful for treating and preventing autoimmune diseases such as atopic dermatitis and systemic lupus erythematous by utilizing a specific natural polymer. SOLUTION: This medicine for inhibiting antibody-producing cells contains a silk-related polymer as an active ingredient. The silk-related polymer is either of silk, a silk extract and the enzymatic degradation product of the silk. The antibody-producing cell-inhibiting medicine is high in the effect for preventing autoimmune diseases, especially atopic dermatitis appearing in dependence on seasons, because the antibody-producing cell-inhibiting medicine can be administered in good timing, before the immune reaction is flared up. One or more kinds of the antibody-producing cell-inhibiting medicines can be added to a medicine composition, a food composition, a skin preparation for external use, a cosmetic, etc. The content of the antibody-producing cell-inhibiting medicine is approximately 0.1-60wt.% in the medicine composition, approximately 0.1-80wt.% in the food composition, and approximately 0.05-30wt.% in the skin preparation for external use or the cosmetic.

8. 发明专利

JPH0930944A AROMATIC AGENT AND CLOTHES CONTAINING THE SAME 失效
公开(公告)号：JPH0930944A
公开(公告)日：1997-02-04
申请号：JP18582695
申请日：1995-07-21
申请人： POLA CHEM IND INC
发明人： OKA NORIAKI , FUKUSHIMA MAKOTO , SAKATA KANZO , USUI YASUICHI , WATANABE SHUJI
IPC分类号： A61F13/42 , A61F5/44 , A61F13/49 , A61K8/33 , A61Q13/00 , C12N9/24 , C12S99/00 , A61K7/46 , C12S13/00
摘要： PROBLEM TO BE SOLVED: To obtain an aromatic agent capable of deodorizing or masking preferably odors contained in a specific ingredient. SOLUTION: This aromatic agent contains a glycoside, having a compound residue having the aromaticity as a constituent element and capable of producing a compound having the aromaticity by hydrolysis with an enzyme as an active ingredient. The saccharide residue which is the constituent element of the glycoside is preferably a residue of oligosaccharides of monosaccharides and/or di-or polysaccharides and the compound having the aromaticity is preferably an alcoholic aromatic compound (e.g. a monoterpene alcohol). Furthermore, the aromatic agent is contained in clothes such as underwear, diapers or sanitary articles so as to provide 0.001-10wt.% content thereof expressed in terms of the glycoside based on the total amount of the clothes to thereby deodorize or mask unpleasant odors such as perspiration or excretions, etc., or the emission thereof can be informed by the aroma. The hydrolase for the glycoside is a glycosidase and/or an oligoglycosidase.

9. 发明专利

JPH0840922A AGENT FOR INHIBITING EXCESSIVE RESPONSE OF HUMAN BODY 失效
公开(公告)号：JPH0840922A
公开(公告)日：1996-02-13
申请号：JP18024194
申请日：1994-08-01
申请人： POLA CHEM IND INC
发明人： FUKUSHIMA MAKOTO , KOSUGE TAKUO
IPC分类号： A61K33/34 , A61K35/14 , A61K35/36 , A61K35/37 , A61K35/413 , A61K35/56 , A61K35/618 , A61K35/62 , A61K35/64 , A61K36/00 , A61K36/18 , A61K36/185 , A61K36/21 , A61K36/234 , A61K36/28 , A61K36/282 , A61K36/286 , A61K36/324 , A61K36/328 , A61K36/35 , A61K36/36 , A61K36/42 , A61K36/48 , A61K36/505 , A61K36/53 , A61K36/533 , A61K36/537 , A61K36/56 , A61K36/65 , A61K36/73 , A61K36/736 , A61K36/80 , A61K36/88 , A61K36/889 , A61K36/8905 , A61K36/906 , A61K36/9066 , A61P29/00 , A61P37/00 , A61P37/06 , A61P37/08 , A61K35/78
摘要： PURPOSE:To obtain a medicine capable of sufficiently inhibiting the excessive response of a living body causing allergic diseases and autoimmune diseases. CONSTITUTION:This agent for inhibiting the excessive response of a human body contains a Chinese medicine having a blood-activating action as an active ingredient preferably in an amount of 1-50wt.%, especially 5-30wt.%. The Chinese medicine includes Ligusticum wallichii, Salvia miltiorrhiza, Millettia reticulata, Irex pubescens Hook. et Arn. Corydalis bulbosa DC., Curcuma aromatica Salisb., Curcuma longa L., Lconurus heterophillus Sweet, Leonurus heterophillus Sweet, Lycopus lucidus Turcz, Camsis gradiflora (Thunb.) Loisei, natural copper, Daemonorops draco Bl., Caesalpinia sappan L., Impatiens balsamina L., Petaurista xanthotis Milne-Edwards, Area granosa L., Manispentadactyla L., Whitmania pigra Whitman, Eupolyphaga sinensis Walk., Naemorhedusgoral Hardwicke, Bas taurusdomesticus Gmelin, and the like. The inhibiting agent is effective for the therapy or preventive therapy of allergic diseases such as pollinosis, hay fever, atopic dermatitis and delayed contact dermatitis, and autoimmune diseases such as systemic lupus erythematosus, periarteritis nodosa, scleroderma, dermatomyositis and chronic articular rheumatism.

10. 发明专利

JPH01287009A COSMETIC 失效
公开(公告)号：JPH01287009A
公开(公告)日：1989-11-17
申请号：JP11406187
申请日：1987-05-11
申请人： POLA CHEM IND INC
发明人： FUKUSHIMA MAKOTO , INAOKA YASUNORI , TANAKA MIKA
IPC分类号： A61K8/49 , A61K8/00 , A61K8/60 , A61K8/96 , A61K8/97 , A61Q19/00
摘要： PURPOSE:To obtain a cosmetic having good feeling of use and stability, presenting effects of skin-beauty and skin-conditioning such as strongness, gloss, smoothness and fresh-looking, etc., in applying to skin, containing skin-beauty component having remedy action of wound, by mixing aloenin, etc. CONSTITUTION:Aloenin expressed by the formula and/or salt of the aloenin obtained by extraction from Aloe in Liliaceae is contained as an active ingredient and mixed a water-soluble polymeric material having >=2,000 molecular weight, such as polypeptide, as necessary to obtain the aimed cosmetic. Aloenins expressed by said formula is white, non-odor powder and readily handled and excellent in mixing properties and solubility to other cosmetic components and capable of applying to all type of agent. Mixing fraction of the aloenins is 0.005-5wt.% of total cosmetic. In extraction of the aloenin expressed by the formula, dried leaf of plant of Aloe, etc., Aloe arborescenes Mill. var. natalensis Berger is roughly clashed, extracted twice by water or organic solvent and purified with a resin column to afford the aloenin expressed by the formula having high purity of 95-99%.

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