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    • 26. 发明专利
    • METHOD AND APPARATUS FOR HEATING AND COOLING OF FERMENTOR
    • JPS5480496A
    • 1979-06-27
    • JP14604477
    • 1977-12-07
    • HITACHI LTD
    • HONDA TERUMICHITSUCHIDA AKIRA
    • C12H1/18C12N1/00
    • PURPOSE:To prevent the concentration of chlorine ion, to economize the latent heat of evaporation of water, and to prevent the steam hammering at the cooling stage, by maintaining the pressure in a cooling coil placed in a fermentor to a value sufficiently high to keep the water liquid, during the heating stage. CONSTITUTION:A fermentor 1 is provided with a cooling coil 2, through which cooling water flows via an inlet 3, outlet 4 and a valve 6, during the cultivation. After the completion of the cultivation, the valve 5 is closed to stop the flow of the cooling water, the cultivation liquid is discharged from the fermentor 1, the fermentor is cleaned, and then fresh cultivation medium is charged into the fermentor. During the sterilization of the medium by introducing steam thereto, the valve 6 is closed and the valve 7 is opened, thereby discharging the expanded water in the coil 2 through a pressure regulating valve 8. The setting pressure of the valve 8 is selected to keep the water liquid at the highest temperature during the sterilization process.