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11. 发明专利

JP2001131016A COMPOSITION FOR EXTERNAL USE 失效
公开(公告)号：JP2001131016A
公开(公告)日：2001-05-15
申请号：JP29190499
申请日：1999-10-14
申请人： SHISEIDO CO LTD
发明人： KUSAKARI TAKESHI , MATSUZAKI FUMIAKI , HARIKI TOSHIO , ABE KOJI
IPC分类号： A61K47/36 , A61K8/00 , A61K8/72 , A61K8/89 , A61K8/891 , A61K8/92 , A61Q19/00 , C08L83/04 , A61K7/00
摘要： PROBLEM TO BE SOLVED: To obtain a composition for external use, e.g. a cosmetic, a medicine for external use for skin, a quasi-drug or the like, which gives an excellent feeling on use without the greasy or residual touch and possesses excellent stability. SOLUTION: This composition for external use is obtained by including (1) a polysaccharide compound which contains [→3)-β-D-glucose (1→4)-β- D-glucuronic acid (1→4)-β-D-glucose(1→4)-α-L-rhamnose (1→] represented by general formula I [wherein, (n) stands for an integer] as a repeated unit and acetyl and glyceryl groups as substituents, preferably in addition, (2) a volatile oil content, e.g. a volatile silicone or the like.

12. 发明专利

JPH09252793A PRODUCTION OF ORGAN CULTURE PRODUCT OF PLANT BELONGING TO GENUS BUPLEURUM AND PRODUCTION OF SAIKOSAPONIN 失效
公开(公告)号：JPH09252793A
公开(公告)日：1997-09-30
申请号：JP9596896
申请日：1996-03-25
申请人： SHISEIDO CO LTD
发明人： FUKUNISHI HIROTADA , KUSAKARI TAKESHI , YOKOYAMA MINEYUKI
IPC分类号： C12P19/44 , C12N5/00 , C12N5/04 , C12R1/91
摘要： PROBLEM TO BE SOLVED: To provide a means capable of further improving production efficiency of saikosaponin in an organ culture of a plant belonging to the genus Bupleurum. SOLUTION: In this method for producing a saikosaponin-containing culture product by the tissue culture of a plant belonging to the genus Bupleurum and capable of producing saikosaponin, the concentration of copper ion (Cu ) in a medium for an organ culture used in the production is adjusted to >=0.2μM to give the objective method for producing saikosaponin. Saikosaponin is purified and collected from the culture product containing saikosaponin obtained by the production to provide the objective method for producing purifying and collecting saikosaponin.

13. 发明专利

JPH08163981A METHOD FOR CULTURING PLANT ORGAN OR CELL AND DEVICE THEREFOR 失效
公开(公告)号：JPH08163981A
公开(公告)日：1996-06-25
申请号：JP33290494
申请日：1994-12-15
申请人： SHISEIDO CO LTD
发明人： KUSAKARI TAKESHI , INOMATA SHINJI , YOKOYAMA MINEYUKI , WACHI YOJI , SAKAMOTO OKIHIKO
IPC分类号： C12M3/00 , C12N5/04
摘要： PURPOSE: To efficiently culture plant organs or cells by using a relevant device designed to culture plant organs or cells with the convection flow of a culture fluid from above downward along a rectified flow wall as well as the culture fluid flow in the wall crossing direction. CONSTITUTION: A porous partition board 70 to divide the inside space of a bubble tower-type culture tank 10 furnished with a porous rectified flow wall 20 inside into a culture section A and aeration section C through combining with the wall 20 is placed on the lower part of the wall 20, the culture section A is afforded, according as necessary, with a means 80 to promote oxygen feed to the medium B on the lower part of the culture section A, and a sparger 30 is attached on the lower part of the aeration section C. Using the culture tank 10 having the above-mentioned scheme, a compressed air fed via a sterile filter 60 is blown out from the sparger 30 to bring a culture fluid convection flow along the wall 20 from above downward, and concurrently, in such a state as to preserve the culture fluid flow in the wall crossing direction, plant organs or cells are cultured efficiently.

14. 发明专利

JPH05184379A PRODUCTION OF SAIKOSAPONIN 失效
公开(公告)号：JPH05184379A
公开(公告)日：1993-07-27
申请号：JP2448092
申请日：1992-01-13
申请人： SHISEIDO CO LTD
发明人： YOKOYAMA MINEYUKI , KUSAKARI TAKESHI , YANAGI MITSUO
IPC分类号： C12N5/02 , C12N5/04 , C12P19/12 , C12R1/91
摘要： PURPOSE:To remarkably increase yield of saikosaponin by culturing a tissue of a plant of the genus Bupleurum in a culture medium to which a phenol derivative is added. CONSTITUTION:When a tissue (preferably regenerated root derived from callus) of a plant of the genus Bupleurum (preferably Bupleurum scorzonera efolium willd.) is cultured to provide saikosaponin, a phenol derivative (e.g. coumarin) is added generally in an addition amount of 0.01-2mM to the culture medium. The culture is preferably carried out at 27 deg.C using a liquid medium or an agar solid medium. Saikosaponin can be separated and purified by extracting, e.g. the cultured root with a lower alcohol, etc., and then treating the extract with a high-performance liquid chromatography.

15. 发明专利

JP2010043012A Antioxidant, anti-aging agent, and external preparation for skin 审中-公开
标题翻译：抗氧化剂，抗老化剂和外用皮肤制剂
公开(公告)号：JP2010043012A
公开(公告)日：2010-02-25
申请号：JP2008206624
申请日：2008-08-11
申请人： Shiseido Co Ltd , 株式会社資生堂
发明人： YOKOI TOKIYA , KUSAKARI TAKESHI , IWAKI HARUHI
IPC分类号： A61K36/18 , A61K8/97 , A61P17/18 , A61P39/06 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide an antioxidant and an anti-aging agent each having high safety and excellent free radical scavenging ability for preventing and suppressing skin aging or skin disorders due to active oxygen (free radicals), and an external preparation for skin formulated therewith. SOLUTION: The antioxidant, anti-aging agent and external preparation for skin contain an extract of one or two or more of plants selected from the group consisting of Barringtonia racemosa, Muntingia calabura, Galphimia glauca, Koelreuteria elegans, Triplaris americana, Calliandra haematocephala Hassk, Calliandra haematocephala and Lucuma nervosa. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供一种抗氧化剂和抗老化剂，其具有高的安全性和优异的自由基清除能力，用于预防和抑制由于活性氧（自由基）引起的皮肤老化或皮肤病症，以及外用制剂用于配制的皮肤。解决方案：抗氧化剂，抗老化剂和皮肤外用剂包含一种或两种以上选自下列组的植物的提取物：选自巴林球菌，马鞭草，玻璃草，秀丽香叶，美洲Trii，美洲Calliandra 血蜱哈斯克，Calliandra haematocephala和Lucuma神经性。版权所有（C）2010，JPO＆INPIT

16. 发明专利

JP2006151822A Agent for retaining freshness of plant with cut root part and two agents mixed type agent set for retaining freshness of plant with cut root part 审中-公开
标题翻译：用于保留具有切割部分和两个代理的植物的清新的代理用于保留具有切割根部的植物的新鲜的混合类型代理
公开(公告)号：JP2006151822A
公开(公告)日：2006-06-15
申请号：JP2004340407
申请日：2004-11-25
申请人： Kumiai Chem Ind Co Ltd , Shiseido Co Ltd , クミアイ化学工業株式会社 , 株式会社資生堂
发明人： YOKOYAMA MINEYUKI , KUSAKARI TAKESHI , WATANABE SATORU
IPC分类号： A01N49/00 , A01N3/02 , A01N37/42
摘要： PROBLEM TO BE SOLVED: To provide an agent for retaining freshness of a plant with cut root part such as a cut flower and an agent set for retaining freshness of the plant.
SOLUTION: The agent for retaining freshness of a plant with cut root part comprises an α-ketol unsaturated fatty acid derivative represented by general formula (1) (R
1 is a 1-5C straight-chain alkyl group or a 2-5C straight-chain unsaturated hydrocarbon group in which the number of double bond is one or two; R
2 is a 1-15C straight-chain alkylene or a 2-15C straight-chain unsaturated hydrocarbon chain in which the number of double bond is 1-3). The two agents mixed type agent for retaining freshness of a plant with cut root part is composed of (A) a plant freshness-retaining composition and (B) another plant freshness-retaining composition for cut plants and the component B comprises, preferably, germicide, boron oxide and saccharides.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：待解决的问题：提供一种用于保持具有切割根部的切割根部的植物的新鲜度的试剂，以及用于保持植物新鲜度的试剂。解决方案：用于保持具根部的植物的新鲜度的试剂包括由通式（1）表示的α-酮醇不饱和脂肪酸衍生物（R 1 是1-5C直链 - 链状烷基或双键数为1或2的2-5C直链不饱和烃基; R SB 2是1-15C直链亚烷基或2-15C直链 - 链不饱和烃链，其中双键数为1-3）。用于保留具有根部的植物的新鲜度的两种混合型试剂由（A）植物保鲜组合物和（B）用于切割植物的另一植物保鲜组合物组成，组分B优选包含杀菌剂，氧化硼和糖类。版权所有（C）2006，JPO＆NCIPI

17. 发明专利

JPH11281559A Apparatus and method for evaluation of stickiness of liquid 失效
标题翻译：用于评估液体粘度的装置和方法
公开(公告)号：JPH11281559A
公开(公告)日：1999-10-15
申请号：JP8520898
申请日：1998-03-31
申请人： Rikagaku Kenkyusho , Shiseido Co Ltd , 株式会社資生堂 , 理化学研究所
发明人： DATE MUNEHIRO , KUSAKARI TAKESHI
IPC分类号： G01N11/00
摘要： PROBLEM TO BE SOLVED: To provide an apparatus and a method, for the evaluation of the stickiness of a liquid, in which the physical property of the liquid (e.g. an emulsion) having a correlative property with the sensitivity of a human being can be measured with high accuracy and with good reproducibility and in which the characteristic of the liquid can be evaluated objectively instead of a sensory analysis which depends on the sensitivity of the human being such as the sticky sensation of cosmetics. SOLUTION: A moving plate 12, a probe 14, an elastic member 16, a probe pressing device 18, a horizontally moving device 20 and a measuring device 22 which measures a force acting on the probe 14 are provided. The probe 14 is composed of a contact maker 14a whose rear surface is formed on an arc face around the horizontal axis (Z) at right angles to the moving direction of the probe 14 and of a holding implement 14b which supports the contact maker 14a so as to be capable of being rolled around the horizontal axis (Z). The contact maker 14a is rolled on the moving plate 12 without being slipped by sandwiching a liquid as a specimen. At this time, a sticky force (or an adhesive force or a threading force) acts as a rolling resistant force on the rear side of the contact maker 14a. On the basis of a change in its rolling force, the characteristic of the liquid is evaluated.
摘要翻译：要解决的问题：提供一种用于评估液体的粘性的装置和方法，其中可以测量与人的灵敏度具有相关性的液体（例如乳液）的物理性质具有高精度和良好的再现性，并且可以客观地评价液体的特性，而不是取决于人的敏感性（诸如化妆品的粘性感觉）的感官分析。解决方案：提供了测量作用在探针14上的力的移动板12，探针14，弹性构件16，探针按压装置18，水平移动装置20和测量装置22。探针14由接触器14a构成，该接触器14a的后表面形成在与探针14的移动方向成直角的水平轴线（Z）的圆弧面上，以及支撑接触器14a的保持工具14b 能够围绕水平轴线（Z）滚动。接触器14a在移动板12上滚动而不会被夹在液体中作为样本而滑动。此时，粘合力（或粘合力或穿线力）作为接触器14a的后侧的滚动阻力。在其滚动力的变化的基础上，评价液体的特性。

18. 发明专利

JPH11281558A Apparatus and method for evaluation of characteristic of emulsion 失效
标题翻译：用于评价乳液特性的装置和方法
公开(公告)号：JPH11281558A
公开(公告)日：1999-10-15
申请号：JP8520798
申请日：1998-03-31
申请人： Rikagaku Kenkyusho , Shiseido Co Ltd , 株式会社資生堂 , 理化学研究所
发明人： DATE MUNEHIRO , KUSAKARI TAKESHI
IPC分类号： G01N11/00
摘要： PROBLEM TO BE SOLVED: To an apparatus and a method, for the evaluation of the characteristic of an emulsion, in which the physical property of the emulsion having a correlative property with the sensitivity of a human being can be measured with high reliability and with good reproducibility and in which the characteristic of the emulsion can be evaluated objectively instead of a sensory analysis which depends on the sensitivity of the human being as in the case of cosmetics.
SOLUTION: A moving plate 12, a probe 14, an elastic member 16 whose lower end is fixed to the probe 14 and which is extended up and down, a probe pressing device 18, a back and forth moving device 20 and a measuring device 22 which measures a sliding force acting on the probe 14 are provided. The rear surface of the probe 14 is formed on an arc face around the horizontal axis (Z) at right angles to the sliding direction of the probe 14. Thereby, even when the elastic member 16 is elastically deformed by a sliding resistance (R) so as to tilt the probe 14, the shape in the contact part of the arc face of the probe 14 with the moving plate 12 is not changed. A vertical force (F) which acts during this time is constant. The probe 14 is not hooked by its back and forth moving operation because it has the arc face. Consequently, the characteristic of an emulsion can be measured on the basis of a change in the sliding force which is measured.
COPYRIGHT: (C)1999,JPO
摘要翻译：要解决的问题：对于具有与人的敏感性具有相关性的乳液的物理性能可以高可靠性和良好的测量的用于评价乳液特性的装置和方法可再现性，并且可以客观地评价乳液的特性，而不是像化妆品那样依赖于人的敏感性的感官分析。解决方案：移动板12，探针14，弹性构件16，其下端固定在探针14上并且上下延伸，探针按压装置18，前后移动装置20和测量装置22 其设置了测量作用在探头14上的滑动力。探针14的后表面与水平轴线（Z）的弧形面成直角，与探头14的滑动方向成直角。由此，即使当弹性部件16由滑动阻力（R）弹性变形时，为了使探针14倾斜，探针14的圆弧面与移动板12的接触部的形状不变化。此时作用的垂直力（F）是常数。探针14由于具有圆弧面而不因其前后移动而被钩住。因此，可以基于测量的滑动力的变化来测量乳液的特性。

19. 发明专利

JPH10279826A TREATED POWDER AND COSMETIC CONTAINING THE SAME 失效
公开(公告)号：JPH10279826A
公开(公告)日：1998-10-20
申请号：JP9663497
申请日：1997-03-31
申请人： SHISEIDO CO LTD
发明人： FUKUI HIROSHI , OSHIMA RIKA , TATE KAZUO , KANAMARU TETSUYA , SUHARA TSUNEO , NAGAYA KYOKO , KUSAKARI TAKESHI
IPC分类号： A61K8/18 , A61K8/26 , A61K8/89 , A61K8/891 , A61Q1/00 , A61Q1/02 , A61Q1/12 , C08L83/05 , C09B67/08 , C09C3/12 , C09K3/00 , A61K7/02
摘要： PROBLEM TO BE SOLVED: To obtain a treated powder excellent in water repellency and dispersibility and a powdery cosmetic material contg. no oil by coating the surface of a powder with a silicone compd. having SiH groups and adding an SiH-reactive compd. to the parts of unreacted SiH groups of the silicone compd. in a specified density. SOLUTION: At least one powder having a particle size of 10 μm or lower and selected from among org. and inorg. pigments, metal oxides and hydroxides, mica, pearlescent materials, metals, etc., is used. It may be in the form of agglomerates or moldings. A superfine powder having a particle size of 0.02 μm or lower can be modified, too. Among silicone oils, silicone resins, silicon waxes, etc., a compd. represented by the formula (R to R are each H or a hydrocarbon group optionally halogenated; R to R are each H, etc.; a is 1 or higher; b is 0, 1, or higher; c is O or 2 provided 3

20. 发明专利

JPH0967388A PRODUCTION OF SAIKOSAPONIN 失效
公开(公告)号：JPH0967388A
公开(公告)日：1997-03-11
申请号：JP24666495
申请日：1995-08-31
申请人： SHISEIDO CO LTD
发明人： INOMATA SHINJI , YOKOYAMA MINEYUKI , KUSAKARI TAKESHI
IPC分类号： C12P19/56 , C07H1/08
摘要： PROBLEM TO BE SOLVED: To efficiently produce a saikosaponin from a plant body. SOLUTION: A crude extract of a plant body containing a saikosaponin is brought into contact with an adsorbent to adsorb the saikosaponin on the adsorbent. Components other than the saikosaponin are then removed from the adsorbent to elute the saikosaponin intactly adsorbed on the adsorbent and collect the natural type saikosaponin. Otherwise, the saikosaponin adsorbed on the adsorbent is brought into contact with iron (III) ions and converted into a saikosaponin having a diene structure. The resultant converted saikosaponin is eluted to collect and afford the saikosaponin having the diene structure.

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