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91. 发明专利

JP2004250352A Peptide useful as ligand 审中-公开
标题翻译：肽可用作配体
公开(公告)号：JP2004250352A
公开(公告)日：2004-09-09
申请号：JP2003040514
申请日：2003-02-19
申请人： Marine Biotechnol Inst Co Ltd , Tosoh Corp , 東ソー株式会社 , 株式会社海洋バイオテクノロジー研究所
发明人： IDE TERUHIKO
IPC分类号： C12N7/02 , C07K1/22 , C07K7/08 , C07K17/02
摘要： PROBLEM TO BE SOLVED: To obtain a binding peptide substance which can adsorb or desorb under mild conditions, has high binding specificity to immune globulins, little deteriorates the binding characteristics on a sterilization treatment or during storage, and has high stability and safety.
SOLUTION: This peptide specifically binds only to the immune globulins in the presence of a metal ion. A means for obtaining the peptide is also provided.
COPYRIGHT: (C)2004,JPO&NCIPI
摘要翻译：待解决的问题：为了获得在温和条件下可以吸附或解吸的结合肽物质，对免疫球蛋白具有高结合特异性，在灭菌处理或储存期间几乎不影响结合特性，并且具有高稳定性和安全性。解决方案：该肽在金属离子的存在下仅特异性结合免疫球蛋白。还提供了获得肽的方法。版权所有（C）2004，JPO＆NCIPI

92. 发明专利

JP2003334064A6 JP2003334064A6 - How to collect water microorganisms 审中-公开
公开(公告)号：JP2003334064A6
公开(公告)日：2004-09-02
申请号：JP2002147108A
申请日：2002-05-22
申请人：株式会社海洋バイオテクノロジー研究所
发明人：美奈安元 , 美由紀西島 , 渉幹 , 芳一志津里
摘要：【課題】水中にわずかしか存在しない菌であっても容易に採取でき、また、特定の機能を持つ微生物を優先的に採取できる方法を提供する。
【解決手段】培地を含浸させた担体を水中に設置し、前記担体に付着した微生物を回収することを特徴とする水中微生物の採取方法。
【選択図】なし

93. 发明专利

JP2004033119A Method for screening enzyme-inhibiting peptide 审中-公开
公开(公告)号：JP2004033119A
公开(公告)日：2004-02-05
申请号：JP2002195510
申请日：2002-07-04
申请人： Marine Biotechnol Inst Co Ltd , 株式会社海洋バイオテクノロジー研究所
发明人： HIYAMUTA SHUICHI
IPC分类号： C12N15/09 , C07K7/08 , C12N9/99 , C12Q1/26
摘要： PROBLEM TO BE SOLVED: To provide a method for enabling an inhibitor of an enzyme having no sharp method for measuring activities to be selected by using a diluted trace candidate material when screening the inhibitor.
SOLUTION: The method for screening an enzyme-inhibiting peptide comprises (1) a step of developing the enzyme on a gel by an electrophoresis, (2) a step of transferring the enzyme developed on the gel to a membrane, (3) a step of soaking the membrane with the transferred enzyme in a solution containing a peptide of a candidate, and (4) a step of confirming whether or not the enzyme transferred to the membrane exhibits the activities.
COPYRIGHT: (C)2004,JPO

94. 发明专利

JP3461527B2 How removal by filamentous fungi of spilled oil 失效
公开(公告)号：JP3461527B2
公开(公告)日：2003-10-27
申请号：JP11343493
申请日：1993-05-14
申请人：株式会社海洋バイオテクノロジー研究所
发明人：雅也浅野 , 勝久白井 , 時男飯塚
IPC分类号： C02F1/40 , C02F3/34 , C12N1/00 , C12N1/14 , C12R1/645 , E02B15/04
CPC分类号： Y02A20/204
摘要： PURPOSE:To effectively remove outflow oil, by diffusing filamentous fungi in the outflow oil on water surface and forming oil balls and after that, rejecting the oil balls. CONSTITUTION:Filamentous fungi which belong to phytophthora genus and have the ability to form mycelium are diffused by 0.01-0.1wt.% of outflown oil water surface. If necessary, nitrogen source like ammonium nitrate, phosphorus source like dipotassium phosphate or carbon source like saccharides are used together therewith. Other applicable filamentous fungi having the ability to form mycelium belong to the genera Saprolegnia, Basidiobolus, Conidiobolus, Cunninghamella, Mortierella, Mucor, Rhizopus, Eupenicillium, Neurospora, Phanerochaete, Aspergillus, Aureobasidium, Beauveria, Cladosporium, Fusarium, Gliocladium, Penicillium, etc.

95. 发明专利

JP2007230911A New antibiotic 有权
标题翻译：新抗生素
公开(公告)号：JP2007230911A
公开(公告)日：2007-09-13
申请号：JP2006055088
申请日：2006-03-01
申请人： Marine Biotechnol Inst Co Ltd , 株式会社海洋バイオテクノロジー研究所
发明人： ADACHI KYOKO , KAWABATA YOSHITAKA , KASAI HIROO , KATSUTA MATSUKO , SHIZURI YOSHIICHI
IPC分类号： C07K7/54 , A61K38/00 , A61P31/04 , C07K5/12 , C12N1/20 , C12N15/09 , C12P21/04
摘要： PROBLEM TO BE SOLVED: To provide a material having a chemical structure different from a well-known antibacterial material, and antibacterial activities, and exhibiting excellent antibacterial activities selective according to kinds of bacteria.
SOLUTION: The antibacterial agent contains a compound represented by formula I (wherein, R
1 is a linear hydrocarbon) or a salt thereof, and a compound represented by formula (II) (wherein, R
2 is a 1-6C linear or branched alkyl group, a 1-6C alkylthioalkyl group or a phenyl group) or a salt thereof as active ingredients.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供具有与众所周知的抗菌材料不同的化学结构的材料和抗菌活性，并且根据细菌种类选择性地表现出优异的抗菌活性。解决方案：抗菌剂含有由式I表示的化合物（其中，R SB 1是直链烃）或其盐，以及式（II）表示的化合物（其中，R 作为活性成分，作为1-6C直链或支链烷基，1-6C烷硫基烷基或苯基）或其盐。版权所有（C）2007，JPO＆INPIT

96. 发明专利

JP2007223969A New antibiotic 有权
标题翻译：新抗生素
公开(公告)号：JP2007223969A
公开(公告)日：2007-09-06
申请号：JP2006048750
申请日：2006-02-24
申请人： Marine Biotechnol Inst Co Ltd , 株式会社海洋バイオテクノロジー研究所
发明人： ADACHI KYOKO , KAWABATA YOSHITAKA , KASAI HIROO , KATSUTA MATSUKO , SHIZURI YOSHIICHI
IPC分类号： C07K5/12 , A61K38/00 , A61P31/04 , C12N1/20 , C12P21/04 , C12R1/01
摘要： PROBLEM TO BE SOLVED: To provide a new compound having a chemical structure differing from known antibacterial compounds and exhibiting excellent antibacterial activity with selectivity according to the kinds of bacteria.
SOLUTION: The new compound represented by the formula(I)[ wherein, R is -(CH
2 )
n CH
3 (n is an integer of 2-6) ] or a salt thereof is provided.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供具有与已知抗菌化合物不同的化学结构的新化合物，并且根据细菌的种类具有优异的抗菌活性和选择性。解决方案：由式（I）表示的新化合物[其中，R为 - （CH 2）2 N CH 3 n为2-6的整数）]或其盐。版权所有（C）2007，JPO＆INPIT

97. 发明专利

JP2007181456A New lipase 有权
标题翻译：新的LIPASE
公开(公告)号：JP2007181456A
公开(公告)日：2007-07-19
申请号：JP2006332622
申请日：2006-12-08
申请人： Marine Biotechnol Inst Co Ltd , Suntory Ltd , サントリー株式会社 , 株式会社海洋バイオテクノロジー研究所
发明人： NAKAO MASAHIRO , KANAMORI MASAKI , FUKAMI JIICHI , KASAI HIROO , OCHIAI MISA
IPC分类号： C12N15/09 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/20 , C12N11/02 , C12P7/64 , C12R1/01
CPC分类号： C12N9/20 , C12P7/6409 , C12P7/6436 , C12R1/01
摘要： PROBLEM TO BE SOLVED: To provide a new lipase and to provide a gene encoding the lipase. SOLUTION: The new lipase is produced by a bacterium of the genus Tetrasphaera and has about 32 kDa molecular weight. A gene has a specific sequence encoding the lipase. Furthermore, the lipase can be recognized with a medium-chain fatty acid as a substrate. Furthermore, the new lipase is produced by the bacterium belonging to the genus Tetrasphaera, can be recognized by using the medium-chain or a long-chain fatty acid as the substrate and has about 40 kDa molecular weight. Furthermore, a polynucleotide has a specific sequence encoding the lipase. In addition, an NITE P-154 strain of the bacterium belonging to the genus Tetrasphaera is provided. The lipase can be used as an immobilized enzyme and is useful in the fields such as the production of a digestant or a flavoring agent, the production of a clinical testing reagent, an enzyme for detergents or an oil and fat and the production of an optically active intermediate for agrochemicals or pharmaceuticals. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：待解决的问题：提供新的脂肪酶并提供编码脂肪酶的基因。解决方案：新型脂肪酶由Tetrasphaera属的细菌产生，分子量约32kDa。基因具有编码脂肪酶的特定序列。此外，脂肪酶可以用中链脂肪酸作为底物来识别。此外，新型脂肪酶由属于四孢属菌属的细菌产生，可以通过使用中链或长链脂肪酸作为底物并且具有约40kDa的分子量来识别。此外，多核苷酸具有编码脂肪酶的特定序列。另外，提供了属于Tetrasphaera属的细菌的NITE P-154菌株。脂肪酶可以用作固定化酶，可用于生产消化剂或调味剂，临床检测试剂的生产，洗涤剂或油脂的酶以及光学上的生产农药或药物的活性中间体。版权所有（C）2007，JPO＆INPIT

98. 发明专利

JP3905604B2 New chemical substance Koror sewing machine 失效
公开(公告)号：JP3905604B2
公开(公告)日：2007-04-18
申请号：JP18677797
申请日：1997-07-11
申请人：株式会社海洋バイオテクノロジー研究所
发明人：浩佐野 , 吉川　　和宏 , 美由紀西島 , 恭子足立 , 貴秀高寺
IPC分类号： C07D407/12 , C12P17/04 , A01N43/08 , C12N1/20 , C12R1/01

99. 发明专利

JP2006160699A New isoprenoid quinone 审中-公开
标题翻译：新ISOPRENOID QUINONE
公开(公告)号：JP2006160699A
公开(公告)日：2006-06-22
申请号：JP2004357556
申请日：2004-12-10
申请人： Marine Biotechnol Inst Co Ltd , 株式会社海洋バイオテクノロジー研究所
发明人： ADACHI KYOKO , HO MANABU , KASAI HIROO , MISAWA NORIHIKO , KATSUTA MATSUKO , SHIZURI YOSHIICHI , MATSUDA SATOSHI
IPC分类号： C07C50/14 , C12N1/20 , C12N15/09 , C12P7/66 , C12Q1/04
摘要： PROBLEM TO BE SOLVED: To provide new indicator compounds for the chemical classification of Nocardia microorganisms, to provide a method for producing the compounds using such microorganisms, and to provide a chemical classification method of the Nocardia microorganisms.
SOLUTION: The compounds are represented by formula(I) and formula(II) respectively. The method for producing the compounds using the microorganisms is provided. The method for classifying the microorganisms with these compounds as indicators is also provided.
COPYRIGHT: (C)2006,JPO&NCIPI

100. 发明专利

JP2006087407A Method for identification of alicyclobacillus acidoterrestris 审中-公开
标题翻译：鉴定ALICYCLOBACILLUS ACIDOTERRESTRIS的方法
公开(公告)号：JP2006087407A
公开(公告)日：2006-04-06
申请号：JP2004280657
申请日：2004-09-27
申请人： Marine Biotechnol Inst Co Ltd , Mitsui Norin Co Ltd , 三井農林株式会社 , 株式会社海洋バイオテクノロジー研究所
发明人： GOTO KEIICHI , ASAHARA MIKA , KASAI HIROO
IPC分类号： C12Q1/68 , C12N15/09
摘要： PROBLEM TO BE SOLVED: To provide a method for identification of Alicyclobacillus acidoterrestris suitable for quickly and easily checking presence/absence of contamination with the Alicyclobacillus acidoterrestris in various creature comforts such as beverage added with fruit juice or its raw material.
SOLUTION: This invention relates to the method for identification characterized by identifying the objective bacillus to be the Alicyclobacillus acidoterrestris by carrying out a LAMP method using the DNA of the bacillus as a template utilizing a primer set containing at least a primer having the whole or a part of a base sequence which has at least continuous 20 bases constituting a specific base sequence contained in gyrB gene encoding a β subunit of a DNA gyrase of the Alicyclobacillus acidoterrestris, and a complementary base sequence of the base sequence, and detecting an amplification of nucleic acid.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供一种鉴定酸性脂环酸杆菌酸酯的方法，适用于快速，容易地检测耐酸脂环酸杆菌的存在/不存在的各种生物舒适性，例如加入果汁或其原料的饮料。解决方案：本发明涉及鉴定方法，其特征在于通过使用使用芽孢杆菌DNA作为模板的LAMP方法鉴定作为酸性脂环酸杆菌酸性杆菌的目标杆菌，所述引物组至少含有具有至少连续20个碱基的全部或部分碱基构成构成编码酸性脂环酸杆菌的DNA促旋酶的β亚单位的gyrB基因中含有的特异性碱基序列的碱基序列，以及碱基序列的互补碱基序列，核酸扩增。版权所有（C）2006，JPO＆NCIPI

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