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    • 6. 发明公开
    • Cyclohexanedione derivatives, their use as herbicides, herbicidal compositions containing them, and methods of preparing them
    • 环己烷衍生物,它们作为除草剂的用途,含有它们的除草剂组合物及其制备方法
    • EP0086588A3
    • 1983-11-16
    • EP83300491
    • 1983-01-31
    • ICI AUSTRALIA LIMITED
    • Serban, AlexanderWatson, Keith GeoffreyBird, Graham JohnCross, Lindsay EdwinFarquharson, Graeme John
    • C07C131/00A01N35/10C07C143/86
    • C07C1/22C07C17/35C07C45/455C07C45/46C07C45/65C07C45/673C07C45/74C07C47/546C07C47/55C07C47/575C07C49/657C07C49/697C07C49/747C07C49/753C07C49/835C07C2602/08C07C13/465C07C25/22C07C49/80C07C49/67C07C49/225
    • The invention concerns novel compounds of the formula I
      wherein:
      W are selected from alkyl, alkenyl and alkynyl; X are selected from halogen, nitro, cyano, alkyl, substituted alkyl, hydroxy, alkoxy, substituted alkoxy, alkenyl, alkynyl, alkenyloxy, alkynyloxy, acyloxy, alkoxycarbonyl, alkylthio, alkylsulfinyl, alkylsulfonyl, sulfamoyl, substituted sulfamoyl, amino, substituted amino, and the groups formyl and alkanoyl and the oxime, imine and Schiff base derivatives thereof, and an alkylene group which bridges two adjacent carbon atoms of the benzene ring; R 1 is selected from hydrogen, alkyl, alkenyl, alkynyl, substituted alkyl, alkylsulfonyl, arylsulfonyl, acyl and an inorganic or organic cation; R 2 is selected from alkyl, substituted alkyl, alkenyl, haloalkenyl, alkynyl and haloalkynyl; R 3 is selected from alkyl, fluoroalkyl, alkenyl, alkynyl, and phenyl; p is zero or an integer selected from 1 to 4; n is zero or an integer selected from 1 to 3; and m is zero or an integer selected from 1 to 3. The compounds of the invention show cereal selective herbicidal properties and plant growth regulating properties and in further embodiments the invention provides processes for the preparation of the compounds of formula I, intermediates useful in the preparation of the compounds of formula I, compositions containing as active ingredient a compound of formula 1, and herbicidal and plant growth regulating processes utilizing compounds of formula I.
    • 本发明涉及式I的新型化合物其中:W选自烷基,烯基和炔基; X选自卤素,硝基,氰基,烷基,取代的烷基,羟基,烷氧基,取代的烷氧基,烯基,炔基,烯氧基,炔氧基,酰氧基,烷氧基羰基,烷硫基,烷基亚磺酰基,烷基磺酰基,氨磺酰基,取代氨磺酰基,氨基,取代的氨基, 并且甲酰基和烷酰基及其肟和亚胺衍生物以及桥接苯环的两个相邻碳原子的亚烷基; R 1选自氢,烷基,烯基,炔基,取代的烷基,烷基磺酰基,芳基磺酰基,酰基和无机或有机阳离子; R 2选自烷基,取代的烷基,烯基,卤代烯基,炔基和卤代炔基; R3选自烷基,氟烷基,烯基,炔基和苯基; p为零或选自1至4的整数; n为0或选自1至3的整数; 本发明的化合物显示出谷物选择性除草性质和植物生长调节性质,并且在进一步的实施方案中,本发明提供了制备式I化合物的方法,可用于 式I化合物的制备,含有式I化合物作为活性成分的组合物,以及利用式I化合物的除草和植物生长调节方法。
    • 10. 发明公开
    • Imidodisulfamide derivatives, their preparation and use in pharmaceutical compositions
    • Imidodisulfamide,ihre Herstellung und ihre Verwendung in pharmazeutischen Zusammensetzungen。
    • EP0034462A2
    • 1981-08-26
    • EP81300548.5
    • 1981-02-11
    • SMITHKLINE BECKMAN CORPORATION
    • Ali, Fadia ElfehallKrell, Robert DonaldSnader, Kenneth Means
    • C07C143/86A61K31/095
    • C07C307/02
    • Compounds of formula (1):-
      and pharmaceutically acceptable salts thereof are disclosed with a process for their preparation.
      In formula (I) A is a covalent bond, an alkylene chain -(CH 2 )n- in which n is a positive integer 2,3,4 or 6, a branched alkylene chain of from 2 to 4 carbon atoms, or phenylmethylene; R 1 is hydrogen, 3- or 4-bromo, 3- or 4-chloro or 3-or 4-trifluoromethyl; and
      R 2 is hydrogen, with the proviso that when n is 2, R 1 is 4-chloro, 4-bromo, 4-methoxy or 3-trifluoromethyl and R 2 is hydrogen or together with R 1 in adjacent positions forms either a 3,4-dichloro substitution or a fused benzo ring, and further with the proviso that when A is a covalent bond R 1 is not hydrogen or 4-chloro.
      The compounds of the invention are SRS-A antagonists.
    • 公开了其制备方法式(1)的化合物: - ... ...及其药学上可接受的盐。 在式(I)中,A是共价键,亚烷基链 - (CH 2)n - ,其中n是正整数2,3,4或6,支链亚烷基链2至4碳 原子或苯基亚甲基; R1是氢,3-或4-溴,3-或4-氯或3-或4-三氟甲基; 并且R 2为氢,条件是当n为2时,R 1为4-氯,4-溴,4-甲氧基或3-三氟甲基,R 2为氢或与R 1在相邻位置形成3,4- 二氯取代或稠合的苯并环,另外条件是当A是共价键时,R 1不是氢或4-氯。 本发明的化合物是SRS-A拮抗剂。