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1. 发明公开

EP4364748A1 USE OF TRADITIONAL CHINESE MEDICINE COMPOSITION IN PREPARATION OF DRUG FOR TREATING COUGH VARIANT ASTHMA 审中-实审
公开(公告)号：EP4364748A1
公开(公告)日：2024-05-08
申请号：EP22831964.6
申请日：2022-06-27
申请人： Shandong New Time Pharmaceutical Co., Ltd.
发明人： ZHANG, Guimin , LI, Xin , LIU, Dongguang
IPC分类号： A61K36/75 , A61K36/538 , A61K36/484 , A61K36/34 , A61K36/238 , A61K36/237 , A61K36/236 , A61K36/233 , A61K36/232 , A61K36/23 , A61K36/076 , A61P11/06
CPC分类号： A61K36/75 , A61K36/233 , A61K36/232 , A61P11/06 , A61K36/484 , A61K36/34 , A61K36/076 , A61K36/23 , A61K36/538 , A61K36/238 , A61K36/237 , A61K36/236
摘要： A traditional Chinese medicinal composition is prepared from herba schizonepetae, radix saposhnikoviae, notopterygium root, radix angelicae pubescentis, radix bupleuri, common hogfennel root, rhizoma chuanxiong, fructus aurantii, poria cocos, radix platycodonis, and liquorice root. The traditional Chinese medicinal composition can reduce the cough frequency of a guinea pig model with cough variant asthma, a percentage of eosinophils in a bronchoalveolar lavage fluid, and a level of serum eosinophil cationic proteins, and has a prevention and treatment effect on the cough variant asthma.

2. 发明公开

EP3892118A1 EISEN-ENTHALTENDE FORMULIERUNG, ERNÄHRUNGSPHYSIOLOGISCHE ZUSAMMENSETZUNG, WELCHE DIESE ENTHÄLTE, UND VERWENDUNG DERSELBEN 审中-公开
公开(公告)号：EP3892118A1
公开(公告)日：2021-10-13
申请号：EP21166880.1
申请日：2021-04-06
申请人： artgerecht GmbH
发明人： Baum, Matthias , Reheis, Daniel
IPC分类号： A23L33/15 , A23L33/165 , A23L33/19 , A61K31/375 , A61K33/26 , A61K36/738 , A61K36/75 , A61K38/40 , A61P1/00 , A61P3/02
摘要： Die Erfindung betrifft eine Formulierung, die Lactoferrin, Eisenverbindungen und Vitamin C umfasst. Sie betrifft ferner eine ernährungsphysiologische Zusammensetzung mit dieser Formulierung und eine magensäurestabile Kapsel mit dieser Formulierung oder dieser ernährungsphysiologischen Zusammensetzung. Schließlich umfasst die Erfindung eine Verwendung der Formulierung oder ernährungsphysiologischen Zusammensetzung für eine ergänzend bilanzierte Diät zur Anwendung bei einem erhöhten Eisenbedarf bei entzündlichen Darmerkrankungen und Unverträglichkeit von Eisensalzen.

3. 发明公开

EP3226880A1 BUCHU PREPARATIONS 无效
标题翻译： BUCHU编制
公开(公告)号：EP3226880A1
公开(公告)日：2017-10-11
申请号：EP15864807.1
申请日：2015-12-01
申请人： Cape Kingdom Nutraceuticals (Pty) Ltd.
发明人： STANDER, Michael Duncombe
IPC分类号： A61K36/75 , A61P31/04 , A61P31/12
CPC分类号： A61K36/75 , A61K9/0014 , A61K9/06 , A61K47/14 , Y02A50/473
摘要： The invention discloses a topical composition, which includes at least one buchu oil extract and at least one buchu water or aqueous extract. The composition includes at least one active ingredient originating from at least one buchu oil extract and at least one buchu water or aqueous extract or bio-active fraction thereof in a pharmaceutically acceptable form. The Buchu oil extract includes about 60% of a betulina buchu variety and about 40% of a crenulata buchu variety. The Buchu oil extract forms about 0.25 weight % of the entire topical formulation. The invention also extends to a sports recovery drink composition, which includes buchu oil, glutamine and beta-carotene.
摘要翻译：本发明公开了局部组合物，其包含至少一种布草油提取物和至少一种布氏水或水性提取物。该组合物包含至少一种源自至少一种布氏油提取物的活性成分和至少一种布可水或其含水提取物或其生物活性部分，其为药学上可接受的形式。 Buchu油提取物包括约60％的金缕梅（Betulina buchu）品种和约40％的布氏（crenulata buchu）品种。 Buchu油提取物形成整个局部制剂的约0.25重量％。本发明还涉及一种运动恢复饮料组合物，其包含buchu油，谷氨酰胺和β-胡萝卜素。

4. 发明授权

EP2554177B1 Cosmetic use of Elemi oil for improving rough skin resulting from the malfunction of the circadian rhythm 有权转让
标题翻译：化妆品使用榄油对由于昼夜节律的故障改善皮肤粗糙
公开(公告)号：EP2554177B1
公开(公告)日：2016-04-27
申请号：EP11762282.9
申请日：2011-03-30
申请人： SHISEIDO COMPANY, LTD.
发明人： GOZU, Yoko , HAZE, Shinichiro , MORI, Keiko , UMISHIO, Kenichi
IPC分类号： A61K36/185 , A61K31/025 , A61K36/00 , A61K36/05 , A61K36/53 , A61K36/73 , A61K36/75 , A61P25/00 , A61P43/00 , A61K36/14 , A61K36/15 , A61K36/324
CPC分类号： A61K36/53 , A61K36/05 , A61K36/14 , A61K36/15 , A61K36/185 , A61K36/28 , A61K36/324 , A61K36/63 , A61K36/67 , A61K36/73 , A61K2300/00

5. 发明公开

EP2883549A4 ANTIMICROBIAL COMPOSITION COMPRISING FILOBASIDIUM-SUPPRESSING AGENT DERIVED FROM NATURAL SUBSTANCE 有权转让
标题翻译：与Filobasidium抗菌成分进行抑制的一种天然物质获得的资金
公开(公告)号：EP2883549A4
公开(公告)日：2016-04-06
申请号：EP13825689
申请日：2013-05-06
申请人： UNIV CHUNG ANG IND
发明人： KIM WON YONG , PARK SANG GUE , PARK HEE KUK
IPC分类号： A61K36/744 , A61K36/75 , A61K36/78 , A61P31/04
CPC分类号： A61K36/75 , A61K8/97 , A61K36/185 , A61K36/31 , A61K36/42 , A61K36/744 , A61K36/78 , A61K2800/59 , A61Q5/006 , A61Q17/005 , A61K2300/00
摘要： The present invention relates to an antimicrobial composition derived from a natural substance. Since the composition effectively suppresses Filobasidium , an organism that has been newly identified as causing dandruff, the present invention can effectively prevent and/or treat seborrhoeic dermatitis and dandruff. Also, since the antimicrobial composition of the present invention includes a natural substance as an active ingredient, little consumer aversion will result. Also, it is expected that the antimicrobial composition of the present invention can be used for developing an antidandruff agent having a reduced content of materials which are typically used as antidandruff agents and the safety of which is questionable.

6. 发明授权

EP2624702B1 ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING 有权
标题翻译：抗生物膜组合物及使用方法
公开(公告)号：EP2624702B1
公开(公告)日：2016-03-02
申请号：EP11831602.5
申请日：2011-10-06
申请人： The Board of Trustees of The University of Arkansas
发明人： QUAVE, Cassandra L. , SMELTZER, Mark S. , COMPADRE, Cesar M. , HENDRICKSON, Howard
IPC分类号： A01N43/90 , A01N65/00 , A01N65/34 , A01P1/00 , A61K38/14 , A61K38/15 , A61K36/75 , A61K36/76 , A61K36/77 , A61K36/87 , A61K36/88
CPC分类号： A01N43/90 , A01N65/00 , A01N65/34 , A61K31/19 , A61K31/192 , A61K31/352 , A61K31/366 , A61K31/43 , A61K31/431 , A61K31/496 , A61K31/65 , A61K31/7048 , A61K31/7056 , A61K36/185 , A61K36/21 , A61K36/23 , A61K36/24 , A61K36/28 , A61K36/40 , A61K36/45 , A61K36/48 , A61K36/49 , A61K36/51 , A61K36/52 , A61K36/53 , A61K36/57 , A61K36/61 , A61K36/73 , A61K36/75 , A61K36/76 , A61K36/77 , A61K36/87 , A61K36/88 , A61K36/896 , A61K38/12 , A61K38/14 , A61K38/15 , Y02A50/478 , A61K2300/00
摘要： The present invention provides polyphenolic compositions derived from a plant that inhibit the formation of a biofilm. Also provided are combinations that comprise at least one phenolic phytochemical and at least one antimicrobial agent that inhibit the growth of an established biofilm. Further, the present invention provides methods for inhibiting the formation and growth of biofilms.

7. 发明公开

EP2939672A1 IGF-1 PRODUCTION PROMOTER 审中-公开
标题翻译： PROMOTER DER IGF-1-PRODUKTION
公开(公告)号：EP2939672A1
公开(公告)日：2015-11-04
申请号：EP13866826.4
申请日：2013-06-28
申请人： Morinaga Milk Industry Co., Ltd.
发明人： OSHIO, Kazutaka , NAKAMURA, Hirohiko , SAKATA, Yasuyuki
IPC分类号： A61K31/352 , A23L1/30 , A61K36/00 , A61K36/75 , A61K47/40 , A61P21/00 , A61P43/00
摘要： An extract of Citrus depressa, preferably a water and/or organic solvent extract of a fruit of leaf of Citrus depressa, a supercritical extract of a fruit of leaf of Citrus depressa, or a subcritical extract of a fruit of leaf of Citrus depressa, which comprise 0. 3 mass % or more of a polymethoxyflavonoid more than in terms of solid matter, for example, an extract of Citrus depressa comprising 0.2 mass % or more of nobiletin and/or 0.1 mass % or more of tangeretin in terms of solid matter, or a polymethoxyflavonoid such as nobiletin or tangeretin is used as an active ingredient of an IGF-1 production-promoting agent.
摘要翻译：柑橘柑橘的提取物，优选柑橘落叶的果实果实的水和/或有机溶剂提取物，柑橘叶的果实的超临界提取物或柑橘叶的果实的亚临界提取物，其中包含比固体物质多0.3质量％以上的多聚甲氧基黄酮，例如，含有0.2质量％以上的诺贝利蛋白和/或固体物质0.1质量％以上的苦参碱的柑橘提取物，或多甲氧基类黄酮如诺贝利或赛替尼作为IGF-1生产促进剂的有效成分。

8. 发明公开

EP2889027A2 Oral preparation, injection preparation, external skin preparation and cosmetic method for preventing or improving wrinkles 有权
标题翻译：口服制剂，注射制剂，用于预防或改善皱纹外用和美容方法皮肤准备
公开(公告)号：EP2889027A2
公开(公告)日：2015-07-01
申请号：EP14167736.9
申请日：2009-03-31
申请人： Shiseido Co., Ltd.
发明人： Iriyama, Shunsuke , Matsunaga, Yukiko , Amano, Satoshi , Umishio, Kenichi , Kusakari, Ken , Hiruma, Takuya
IPC分类号： A61K8/46 , A61K8/49 , A61K31/17 , A61K31/4184 , A61K36/00 , A61K36/18 , A61K36/23 , A61K36/73 , A61K36/75 , A61K36/81 , A61K36/896 , A61K45/00 , A61P17/00 , A61Q19/08
CPC分类号： A61K36/00 , A61K8/4946 , A61K8/66 , A61K8/97 , A61K9/0014 , A61K9/0019 , A61K9/0053 , A61K31/17 , A61K31/4184 , A61K36/14 , A61K36/18 , A61K36/185 , A61K36/23 , A61K36/725 , A61K36/73 , A61K36/75 , A61K36/752 , A61K36/81 , A61K36/896 , A61K36/8962 , A61K36/8967 , A61K2800/5922 , A61K2800/91 , A61K2800/92 , A61Q19/007 , A61Q19/08 , G01N33/573 , G01N2333/924 , G01N2500/04 , G01N2500/10
摘要： Wrinkles are improved by applying an oral preparation, injection preparation or external skin preparation having a substance that controls heparanase as an active ingredient thereof.
摘要翻译：皱纹通过施加于口服制剂，注射剂或具有物质做对照肝素酶作为其活性成分的皮肤外用剂的改善。

9. 发明公开

EP2883548A1 FILAGGRIN GENE EXPRESSION PROMOTER 有权
标题翻译：聚角蛋白微丝-GEN-EXPRESSIONSPROMOTER
公开(公告)号：EP2883548A1
公开(公告)日：2015-06-17
申请号：EP13828308.0
申请日：2013-03-29
申请人： Shiseido Company Ltd.
发明人： GOZU, Yoko , HAZE, Shinichiro
IPC分类号： A61K36/00 , A61K8/37 , A61K8/41 , A61K8/97 , A61K31/235 , A61K31/245 , A61K36/18 , A61K36/23 , A61K36/53 , A61K36/73 , A61K36/75 , A61P17/00 , A61P43/00 , A61Q13/00 , A61Q19/00 , A61Q19/10 , C12N15/09
CPC分类号： A61K8/97 , A61K8/37 , A61K8/411 , A61K8/44 , A61K8/445 , A61K8/4926 , A61K8/922 , A61K9/0014 , A61K9/06 , A61K9/2018 , A61K9/2068 , A61K9/5042 , A61K31/235 , A61K31/245 , A61K36/14 , A61K36/185 , A61K36/23 , A61K36/53 , A61K36/67 , A61K36/73 , A61K36/758 , A61K47/10 , A61K47/14 , A61K47/44 , A61K2800/70 , A61K2800/74 , A61Q19/00 , A61Q19/007 , A61K2300/00
摘要： The present invention provides a novel substance that promotes expression of filaggrin gene involved in improvement of the moisture retention function of skin. The inventors of the present invention found that expression of filaggrin gene fluctuates rhythmically over a roughly 24 hour cycle, screened candidate substances based on the time at which expression reaches a maximum following addition of the candidate substance, and identified zanthoxylum extract, 3-(1'-piperidine)propionic acid, geranium oil, cypress oil, rose oil, galvanum oil, pepper oil, basil oil, methyl-o-toluate, methyl anthranilate and dimethyl anthranilate as filaggrin gene expression promoting agents.
摘要翻译：本发明提供促进丝聚蛋白基因表达的新型物质，其涉及改善皮肤的保湿功能。本发明的发明人发现丝聚蛋白基因的表达在大约24小时周期内有节奏地波动，基于候选物质添加后表达达到最大值的时间筛选候选物质，并鉴定了花椒提取物3-（1 β-哌啶）丙酸，天竺葵油，柏油，玫瑰油，原油，胡椒油，罗勒油，甲基邻甲苯甲酸酯，邻氨基苯甲酸甲酯和邻氨基苯甲酸二甲酯作为丝胶蛋白基因表达促进剂。

10. 发明公开

EP2606874A3 Nouvelles compositions cosmetiques et/ou pharmaceutiques et leurs applications 有权转让
标题翻译：新的化妆品和/或药物组合物以及它们的应用
公开(公告)号：EP2606874A3
公开(公告)日：2013-08-14
申请号：EP12186394.8
申请日：2008-02-08
申请人： Legacy Healthcare Holding Ltd.
发明人： Ulmann, André , Sturer, Jean-Frédéric
IPC分类号： A61K8/27 , A61K8/97 , A61Q5/00 , A61Q7/00 , A61Q19/00 , A61K36/00 , A61K36/896 , A61K8/896 , A61K36/75 , A61K36/76
CPC分类号： A61K36/88 , A61K8/27 , A61K8/97 , A61K36/00 , A61K36/185 , A61K36/75 , A61K36/752 , A61K36/76 , A61K36/77 , A61K36/896 , A61K36/8962 , A61K2800/92 , A61Q5/00 , A61Q7/00 , A61Q19/00
摘要： Compositions, caractérisées en ce qu'elles renferment à titre de principes actifs : un extrait d'Allium species, un extrait de Citrus species et,
- soit un extrait de Paullinia species et un extrait de Theobroma species,
- soit un extrait de Salix species et du sulfate de zinc
Procédé de préparation de ces compositions.
Application cosmétique et/ou pharmaceutique de ces compositions.
摘要翻译：组合物，其包括葱属和柑橘提取物和泡林藤和可可提取物的组合或柳提取物和硫酸锌的组合是新的。因此独立claimsoft包括例如通过制备母液含葱属和柑橘提取物和用泡林藤和可可提取物的组合或柳提取物和硫酸锌的组合混合母液生产如上述的组合物。活动：皮肤病; 伤药; 角质; Vasotropic。无生物数据给出。作用机理：没有给出。

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